Multistage biomimetic spine-like micro-robot for lung sampling and method of making the same
By designing a multi-level biomimetic spiky microrobot, and utilizing the synergistic effect of micron-level microspiky and nano-level gold spike structures, the lung sampling problem in existing technologies has been solved, achieving stable scraping of airway tissue and cells and adjustable sampling depth.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HARBIN INSTITUTE OF TECHNOLOGY (SHENZHEN) (INSTITUTE OF SCIENCE AND TECHNOLOGY INNOVATION HARBIN INSTITUTE OF TECHNOLOGY SHENZHEN)
- Filing Date
- 2026-04-20
- Publication Date
- 2026-07-17
AI Technical Summary
Existing microrobots have difficulty effectively scraping airway epithelial tissue or cells from the lungs, and lack the ability to control the sampling depth, resulting in easy sample detachment and making it difficult to meet clinical diagnostic needs.
A multi-level biomimetic spiky microrobot is designed, combining micron-level microspiky and nano-level gold spike structures. It utilizes magnetically driven rotational motion to achieve mechanical scraping and micro/nano entanglement. By integrating a magnetically driven inner cylinder with a multifunctional sampling outer shell, it achieves multi-level interactive sampling of airway tissues and stable sample anchoring.
It achieves effective scraping of airway tissue and cells, and the sample remains stably attached during the robot's movement. It can adjust the sampling depth according to the depth of the lesion to obtain samples with histological diagnostic value.
Smart Images

Figure CN122398375A_ABST