An anti-inflammatory and analgesic extract tablet of radix curcumae and its preparation process

By preparing chyluria-reducing extract tablets, the problems of unstable efficacy and high toxicity of existing drugs for treating filariasis and lymphedema and other lymphatic system diseases caused by various etiologies have been solved. This provides a highly efficient, safe, and economical treatment option, achieving effective protection of the lymphatic system and promoting lymphatic return.

CN122398891APending Publication Date: 2026-07-17

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Filing Date
2026-05-06
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing drug therapies for filariasis and lymphatic system diseases such as chyluria and lymphedema caused by various etiologies suffer from unstable efficacy, high toxicity, and low patient compliance, and there is a lack of safe and effective drug treatment options.

Method used

This invention provides a tablet containing chyle-clearing extract for reducing swelling. By transforming a traditional Chinese medicine formula into a modern preparation, it employs a high drug loading formula and a stable extraction process. Combined with TLC identification and HPLC content determination methods, quality control is ensured. Its anti-inflammatory, lymphatic endothelial protective, and lymphatic drainage mechanisms are verified through animal experiments and clinical studies.

Benefits of technology

It provides efficient, safe, and economical long-term treatment options for diseases such as chyluria and lymphedema. By establishing quality control standards and clear efficacy evaluation, it ensures the high efficiency and reproducibility of the treatment, and elucidates its mechanism of action at the cellular level, significantly reducing lymphedema and inflammation.

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Abstract

本申请公开了一种消肿乳糜清浸膏片剂及其制备工艺,消肿乳糜清浸膏片剂,包括如下质量份数的质量比,生药粉0.8‑1.2:浸膏粉1.2‑0.8:辅料0.015‑0.025,其中,生药粉和浸膏粉分别为含有黄酮类、甾类和维生素类的中药材,其制备工艺是从临床验方水煎剂而来,该药材经两次煮沸提取能将有效成分完全提出。为掩盖本品的色、嗅,设计薄膜包衣片剂的制备工艺。本申请实施例的消肿乳糜清浸膏片剂及其制备工艺,不仅解决了乳糜尿、淋巴水肿等疾病长期缺乏高效安全专用药物的临床难题,更通过完整的药学、药理、毒理和临床研究,建立了该中药制剂的质量控制标准,并从细胞层面阐明了其抗炎、保护淋巴管内皮、促进淋巴回流的多靶点作用机制,是理想的天然治疗药物。
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