A transcranial electrical stimulation system and method based on multi-modal feedback and MRI guidance

By using MRI guidance and a multimodal feedback system, combined with multi-channel time-domain interference current and neural monitoring, the problems of poor targeting and insufficient real-time feedback in deep brain regions in traditional transcranial electrical stimulation techniques have been solved, achieving precise, safe, and individualized neuromodulation of deep brain regions.

CN122399245APending Publication Date: 2026-07-17BEIJING HENGZHI TECH CO LTD
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Patent Information

Application Number
CN202610815974.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-08
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional transcranial electrical stimulation (TCS) techniques are difficult to achieve precise targeted stimulation of deep brain regions and lack real-time neural feedback mechanisms, resulting in significant individual differences and difficulty in ensuring safety.

Method used

By employing an MRI-guided multimodal feedback system, a closed-loop feedback mechanism is established by constructing a personalized head model and combining multi-channel time-domain interference current and multimodal neural monitoring to achieve precise stimulation and real-time parameter adjustment of deep brain regions.

Benefits of technology

It significantly improves the spatial specificity and targeting accuracy of neuromodulation, ensuring individualized adaptation and safety, and achieving precise, focused stimulation and real-time feedback to deep brain regions.

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Abstract

本申请提供一种基于多模态反馈与MRI引导的经颅电刺激系统和方法,包括:MRI结构像引导模块,用于获取目标对象的颅脑核磁共振影像,计算针对目标深部脑区的最优电极刺激位点;多通道经颅电刺激模块,用于根据所述最优电极刺激位点,通过多通道电极阵列向所述目标深部脑区输出时域干涉电流;多模态神经监测模块,用于实时采集目标对象的近红外脑功能数据和 / 或脑电信号;反馈调控处理模块,用于建立电刺激参数与神经响应的定量映射关系,动态调整所述多通道经颅电刺激模块输出的所述时域干涉电流参数。根据本申请的技术方案能够提升非侵入性神经调控的精准性、有效性与安全性。
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