A system and method for combined detection and evaluation of active ingredients and safety indicators of genuine medicinal materials

By employing multidimensional synchronous extraction and synergistic detection technology, the problems of high sample loss and long cycle in the testing of Chinese medicinal materials have been solved. This technology enables the synchronous detection and correlation evaluation of active ingredients and safety indicators, providing an efficient and low-loss comprehensive quality assessment method.

CN122409915APending Publication Date: 2026-07-17HEILONGJIANG ACAD OF FORESTRY SCI YICHUN BRANCH
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Patent Information

Application Number
CN202610758387.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-29
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Current methods for quality testing of Chinese medicinal materials suffer from problems such as high sample loss, long testing cycles, and fragmented data dimensions, making it difficult to achieve simultaneous, efficient, low-loss detection and correlation evaluation of active ingredients and safety indicators.

Method used

A multidimensional synchronous extraction module was used to extract authentic medicinal materials simultaneously, and a liquid chromatography-mass spectrometry (LC-MS) and inductively coupled plasma mass spectrometry (ICP-MS) detection unit were used for collaborative detection. Combined with a multidimensional data fusion and correlation evaluation module, a correlation evaluation model between active ingredients and harmful substances was established.

Benefits of technology

It enables one-stop simultaneous detection of active ingredients and safety indicators of authentic medicinal materials, shortens the detection cycle, reduces sample loss, and establishes a correlation evaluation model between active ingredients and harmful substances, providing a basis for comprehensive quality assessment.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一种道地药材活性成分与安全性指标的联检评价系统及方法,所述系统包括多维同步提取模块,用于对道地药材样品进行同步提取处理,得到含活性成分待测液和含有害物质待测液;协同检测模块包括液相色谱‑质谱联用检测单元和电感耦合等离子体质谱检测单元,用于对所述含活性成分待测液进行分离和定性定量分析,得到活性成分检测数据,以及对含有害物质待测液中的农药残留和重金属元素进行同步检测,得到安全性检测数据;多维数据融合与关联性评价模块,用于基于所述活性成分检测数据和所述安全性检测数据进行融合分析,建立活性成分与有害物质之间的关联性评价模型,输出联检评价结果。本发明能提实现一次性同步提取和一站式同步检测。
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