Application of traditional Chinese medicine composition based on depression regulating and subsidence ascending decoction in preparation of medicine for treating qi deficiency and blood stasis type pulmonary nodule

By adjusting the formulation and preparation process of Liyu Shengxian Decoction, a traditional Chinese medicine composition honey pill suitable for pulmonary nodules of qi deficiency and blood stasis type was prepared, which solved the problem of the lack of traditional Chinese medicine solutions for directly treating pulmonary nodules of qi deficiency and blood stasis type in the existing technology and achieved significant therapeutic effects.

CN122440700APending Publication Date: 2026-07-24TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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Patent Information

Application Number
CN202610629576.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-09
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

In the existing technology, Liyu Shengxian Decoction is mainly used for conditioning and treatment of patients after pulmonary nodule resection. There are no reports of its direct application in the treatment of pulmonary nodules of qi deficiency and blood stasis type, and there is a lack of effective Chinese medicine treatment options.

Method used

The original formula of Liyu Shengxian Decoction was adjusted, omitting Anemarrhena asphodeloides and optimizing the dosage relationship of Astragalus membranaceus and Angelica sinensis. The traditional Chinese medicine composition was prepared by reflux extraction with a specific solvent and concentration and drying process to form a honey pill dosage form for the treatment of pulmonary nodules of qi deficiency and blood stasis type.

Benefits of technology

It significantly improved the treatment effect on pulmonary nodules of Qi deficiency and blood stasis type, and significantly increased the reduction rate of pulmonary nodules, providing a more effective Chinese medicine treatment plan.

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Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to application of a traditional Chinese medicine composition based on depression regulating and subsidence ascending decoction to preparation of medicine for treating qi deficiency and blood stasis type pulmonary nodules, and the traditional Chinese medicine composition is prepared from, by weight, 15-21 parts of raw radix astragali, 9-17.5 parts of angelica sinensis bodies, 7-10 parts of frankincense, 7-10 parts of myrrh, 3-5 parts of cassia twig tips and 3-5 parts of radix bupleuri. On the basis of the depression regulating and subsidence ascending decoction, the invention finds that rhizoma anemarrhenae in the original formula is omitted, the use amount relation of the raw astragalus membranaceus and the angelica sinensis is adjusted, the preparation process is optimized, and clinical verification shows that the treatment effect on the qi deficiency and blood stasis type pulmonary nodule patients can be remarkably improved. Therefore, the invention provides the traditional Chinese medicine composition for treating qi deficiency and blood stasis type pulmonary nodules based on the depression regulating and subsidence ascending decoction, the traditional Chinese medicine composition can be further prepared into traditional Chinese medicine honeyed boluses and other dosage forms and is applied to clinical treatment of qi deficiency and blood stasis type pulmonary nodules, and the traditional Chinese medicine composition is simple in formula, good in treatment effect and wide in application prospect.
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