Fluorescent dye reagent split charging device
By designing a fluorescent dye reagent dispensing device equipped with a light-proof shell, refrigeration sheet and oscillator, the problem that the existing devices cannot meet the requirements of low temperature and light protection is solved, and efficient and stable fluorescent reagent dispensing is achieved, ensuring that Reagent quality and titer.
Patent Information
- Application Number
- CN202421370271.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-14
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2034-06-14
AI Technical Summary
The existing fluorescent reagent aliquoting device cannot meet the requirements of low temperature avoidance, resulting in fluorescence quenching of the reagent during the aliquoting process, affecting the reagent titer and product quality.
A fluorescent dye reagent package device is designed, using a light-proof shell, a refrigeration sheet and an oscillator to realize the functions of low temperature light-proof and shock-proof mixing.
The device can perform reagent aliquots under low temperature and light-proof conditions, avoid fluorescence quenching, ensure reagent quality and titer, and solve the problem that existing devices cannot achieve low temperature and light-proof pipetting.
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Figure CN222497068U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the field of biological reagent packaging auxiliary tools, and in particular relates to a fluorescent dye reagent packaging device. Background Art
[0002] During the packaging process of fluorescent reagents, in order to avoid fluorescence quenching, it is necessary to proceed under light-proof and low-temperature conditions.
[0003] Currently, the packaging of fluorescent reagents is done in a dark room without turning on the lights. Ice cubes or ice boxes are placed on the operating table to package the reagents. After packaging, the reagent tubes need to be placed on an oscillator for shaking and mixing. The operation is time-consuming and cumbersome. In addition, fluorescence quenching will occur when the reagent leaves the ice box, resulting in a decrease in the potency of the reagent. In severe cases, the product may be unqualified.
[0004] Currently, many packaging devices on the market, such as pipettes, are only suitable for packaging conventional reagents and cannot meet the requirements of low temperature and light protection; conventional reagent mixers on the market do not have low temperature and light protection functions. Utility Model Content
[0005] In view of the deficiencies in the prior art, the utility model provides a fluorescent dye reagent packaging device, which has the functions of light protection, low temperature control and oscillation mixing.
[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a fluorescent dye reagent dispensing device, comprising a shell and a cover plate;
[0007] The shell is a light-proof shell, a cooling plate is provided on the inner side wall of the shell, an oscillator is provided at the inner bottom of the shell, a reagent bottle is placed on the oscillator, the top of the shell is open, the cover plate is arranged at the top opening of the shell, a liquid inlet and a liquid outlet are penetrated on the cover plate, a liquid inlet pipe is inserted into the liquid inlet, the inner end of the liquid inlet pipe extends into the reagent bottle, a liquid outlet pipe is inserted into the liquid outlet, the inner end of the liquid outlet pipe extends into the reagent bottle.
[0008] Preferably, a temperature display screen is provided on the outer side wall of the shell, a thermometer is provided inside the shell, and the temperature display screen is electrically connected to the thermometer.
[0009] Preferably, a transparent scale observation window is provided on the outer side wall of the shell.
[0010] Preferably, a reagent inlet and outlet button is provided on the cover plate.
[0011] Preferably, the cover plate is provided with a reagent volume display screen and a reagent volume adjustment button.
[0012] Preferably, the top opening of the shell is a circular structure, and the cover plate is a circular cover plate.
[0013] Preferably, the device further comprises a motor for driving the oscillator to oscillate.
[0014] Preferably, a slot is provided at the bottom of the shell, and the oscillator and the motor are both mounted in the slot.
[0015] Compared with the prior art, the beneficial effects of the utility model are:
[0016] The utility model provides a fluorescent dye reagent dispensing device, wherein the light-proof housing can achieve a light-proof effect inside the housing, the cooling sheet can achieve low-temperature control inside the housing, and the oscillator can achieve oscillation and mixing of the reagent bottle, that is, the device has the functions of light-proof, low-temperature temperature control and oscillation and mixing at the same time, which can ensure that the quality of the fluorescent reagent dispensed is not affected by the external environment. The defect that the existing products cannot achieve low-temperature light-proof liquid transfer is solved. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 A schematic diagram of the three-dimensional structure of a fluorescent dye reagent packaging device provided in an embodiment of the utility model;
[0018] Figure 2 A schematic diagram of the three-dimensional structure of a housing and related parts of a fluorescent dye reagent dispensing device provided in an embodiment of the utility model;
[0019] Figure 3 A schematic diagram of the three-dimensional structure of a reagent bottle and related parts of a fluorescent dye reagent dispensing device provided in an embodiment of the utility model;
[0020] Figure 4 A schematic diagram of the top view of the cover plate of a fluorescent dye reagent dispensing device provided in an embodiment of the utility model;
[0021] Figure 5 The present invention provides a schematic cross-sectional structure diagram of a fluorescent dye reagent packaging device provided in an embodiment of the present invention.
[0022] In the accompanying drawings, the components represented by the reference numerals are listed as follows:
[0023] 1. Reagent volume display screen; 2. Reagent volume adjustment button; 3. Liquid inlet; 4. Liquid outlet; 5. Reagent inlet and outlet buttons; 6. Liquid inlet pipe; 7. Liquid outlet pipe; 8. Reagent bottle; 9. Oscillator; 10. Motor; 11. Refrigeration plate; 12. Temperature display screen; 13. Shell; 14. Transparent scale observation window; 15. Cover plate. DETAILED DESCRIPTION
[0024] The present invention will be further described in detail below in conjunction with specific embodiments so that those skilled in the art can understand the present invention more clearly.
[0025] It should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integrally formed structure. For ordinary technicians in this field, the specific meanings of such terms in this patent can be understood according to specific circumstances.
[0026] Example 1
[0027] like Figure 1-5 As shown, this embodiment provides a fluorescent dye reagent packaging device, including a shell 13 and a cover plate 15.
[0028] The housing 13 is a light-proof housing, that is, the housing 13 is made of a light-proof material, so that the interior of the housing 13 can achieve a light-proof function.
[0029] A cooling fin 11 is installed on the inner wall of the shell 13 . The cooling fin 11 is a semiconductor cooling fin. The low temperature control function inside the shell 13 can be achieved through the cooling fin 11 .
[0030] An oscillator 9 is provided at the bottom of the shell 13, and a reagent bottle 8 is placed on the oscillator 9. The oscillator 9 can realize the function of oscillating and mixing the reagent bottle 8. At the same time, since the reagent bottle 8 is located inside the shell 13, the device has the functions of light protection, low temperature control and oscillation mixing, which can ensure that the reagent bottle 8 is not affected by the external environment.
[0031] The shell 13 has an opening at the top and is larger than the reagent bottle 8. The opening at the top of the shell 13 is a circular structure. The cover 15 is a circular cover for easy removal or placement of the reagent bottle 8. The cover 15 is arranged at the opening at the top of the shell 13 to play a sealing role.
[0032] The cover plate 15 is provided with a liquid inlet 3 and a liquid outlet 4. A liquid inlet pipe 6 is inserted into the liquid inlet 3, and the inner end of the liquid inlet pipe 6 extends into the reagent bottle 8, that is, liquid can be introduced into the reagent bottle 8 from the outside of the shell 13 through the liquid inlet pipe 6. A liquid outlet pipe 7 is inserted into the liquid outlet 4, and the inner end of the liquid outlet pipe 7 extends into the reagent bottle 8, that is, the reagent in the reagent bottle 8 can be packaged through the liquid outlet pipe 7. The liquid inlet pipe 6 is matched with the liquid inlet 3 so that the liquid inlet pipe 6 can be stably inserted into the liquid inlet 3, and the liquid outlet pipe 7 is matched with the liquid outlet 4 so that the liquid outlet pipe 7 can be stably inserted into the liquid outlet 4.
[0033] Based on the above structure, the fluorescent dye reagent dispensing device provided in this embodiment, when performing the reagent dispensing operation, first turn on the power supply and turn on the refrigeration plate 11 for refrigeration. After waiting for about 5 minutes, the temperature in the shell 13 is 2°C-8°C, and the reagent bottle 8 is placed on the oscillator 9, covered with the cover plate 15, and the liquid inlet pipe 6 and the liquid outlet pipe 7 are inserted. The other end of the liquid inlet pipe 6 is inserted into the reagent sample tube to absorb the liquid. The liquid inlet pipe 6 needs to be replaced after each reagent absorption. During the absorption process, the oscillator 9 always maintains an oscillating state. After all reagents are absorbed, the reagent mixing is also completed. Then the other end of the liquid outlet pipe 7 is inserted into the dispensing tube, and the reagent in the reagent bottle 8 is sucked into the dispensing tube to complete the fluorescent dye reagent dispensing.
[0034] In summary, the fluorescent dye reagent packaging device provided in this embodiment has the functions of light protection, low temperature temperature control and oscillation mixing, which can ensure that the quality of the packaged fluorescent reagent is not affected by the external environment, and solves the defect that existing products cannot achieve low temperature and light-proof pipetting.
[0035] In this embodiment, a temperature display screen 12 is provided on the outer wall of the housing 13, a thermometer is provided in the housing 13, and the temperature display screen 12 is electrically connected to the thermometer. The temperature display screen 12 can display the temperature in the housing 13 in real time, which is convenient for the staff to perform low temperature control.
[0036] A transparent scale observation window 14 is provided on the outer side wall of the housing 13. Through the transparent scale observation window 14, the situation inside the housing 13 can be observed in real time, which is convenient for the staff to observe the reagent capacity in the reagent bottle 8.
[0037] like Figure 4 As shown, the cover plate 15 is provided with a reagent inlet and outlet button 5. The reagent inlet and outlet button 5 can control the inlet and outlet of liquid. For example, the liquid inlet pipe 6 and the liquid outlet pipe 7 are both provided with a suction pump, and the reagent inlet and outlet button 5 is electrically connected to the suction pump. The opening and closing of the suction pump can be controlled by the reagent inlet and outlet button 5, thereby achieving liquid inlet and outlet.
[0038] The cover plate 15 is provided with a reagent volume display screen 1 and a reagent volume adjustment button 2 .
[0039] The reagent volume adjustment button 2 can adjust the preset volume in the reagent bottle 8. For example, the suction pump is electrically connected to a single-chip microcomputer, and the single-chip microcomputer can calculate and control the suction amount of the suction pump, so that the reagent volume in the reagent bottle 8 can be preset. The reagent volume adjustment button 2 is electrically connected to the single-chip microcomputer, and the reagent volume adjustment button 2 can control the size of the preset volume.
[0040] The reagent volume display screen 1 is electrically connected to the single chip computer. The reagent volume display screen 1 can display the real-time volume and preset volume of the reagent in the reagent bottle 8.
[0041] The fluorescent dye reagent dispensing device provided in this embodiment further includes a motor 10 for driving the oscillator 9 to oscillate. Figure 5 As shown, a slot is provided at the bottom of the housing 13, and the oscillator 9 and the motor 10 are both mounted in the slot, so that the position of the oscillator 9 can be kept unchanged.
[0042] The housing 13 may be provided with a placement groove adapted to the reagent bottle 8, the size of the placement groove being slightly larger than the reagent bottle 8, the placement groove being connected to the card slot, and the placement groove may prevent the reagent bottle 8 from tipping over due to vibration. At the same time, the liquid inlet pipe 6 and the liquid outlet pipe 7 may also play a certain limiting role, preventing the reagent bottle 8 from tipping over due to excessive shaking.
[0043] The mechanisms, components and parts not specifically described in the present invention are all existing structures in the prior art and can be directly purchased from the market.
[0044] In the description of the present utility model, it should be understood that the terms "upper", "lower", "left", "right", etc. indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, and a specific direction structure and operation, and therefore, cannot be understood as a limitation on the present utility model. In addition, "first" and "second" are only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, unless otherwise specified, "multiple" means two or more.
[0045] The above is only a preferred embodiment of the utility model, and is not intended to limit the protection scope of the utility model. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.
Claims
1. A fluorescent dye reagent packaging device, characterized in that: It comprises a housing (13) and a cover plate (15); The shell (13) is a light-proof shell. A cooling plate (11) is provided on the inner side wall of the shell (13). An oscillator (9) is provided on the inner bottom of the shell (13). A reagent bottle (8) is placed on the oscillator (9). The top of the shell (13) is open. The cover plate (15) is arranged to cover the top opening of the shell (13). A liquid inlet (3) and a liquid outlet (4) are provided through the cover plate (15). A liquid inlet pipe (6) is inserted into the liquid inlet (3). The inner end of the liquid inlet pipe (6) extends into the reagent bottle (8). A liquid outlet pipe (7) is inserted into the liquid outlet (4). The inner end of the liquid outlet pipe (7) extends into the reagent bottle (8).
2. A fluorescent dye reagent packaging device according to claim 1, characterized in that: A temperature display screen (12) is provided on the outer wall of the shell (13), a thermometer is provided inside the shell (13), and the temperature display screen (12) is electrically connected to the thermometer.
3. A fluorescent dye reagent packaging device according to claim 1, characterized in that: A transparent scale observation window (14) is provided on the outer side wall of the housing (13).
4. A fluorescent dye reagent packaging device according to claim 1, characterized in that: The cover plate (15) is provided with a reagent inlet and outlet button (5).
5. A fluorescent dye reagent packaging device according to claim 1, characterized in that: The cover plate (15) is provided with a reagent volume display screen (1) and a reagent volume adjustment button (2).
6. A fluorescent dye reagent packaging device according to claim 1, characterized in that: The top opening of the shell (13) is a circular structure, and the cover plate (15) is a circular cover plate.
7. A fluorescent dye reagent packaging device according to claim 1, characterized in that: The device also includes a motor (10) for driving the oscillator (9) to oscillate.
8. A fluorescent dye reagent packaging device according to claim 7, characterized in that: The inner bottom of the housing (13) is provided with a slot, and the oscillator (9) and the motor (10) are both mounted in the slot.