Cell counting detection optical lens module and cell counting detection device with same

Abstract

The utility model discloses a cell counting detection optical lens module and a cell counting detection device with the same. The optical lens module comprises a first lens, a second lens and a third lens which are sequentially arranged from an object side to an image side along an optical axis direction, the first lens has positive focal power, the object side surface of the first lens is a convex surface, and the image side surface of the first lens is a convex surface; the second lens has negative focal power, the object side surface of the second lens is a concave surface, and the image side surface of the second lens is a concave surface; the third lens has positive focal power, the object side surface of the third lens is a convex surface, and the image side surface of the third lens is a convex surface; wherein the optical total length TTL of the optical lens module and the effective focal length f of the optical lens module meet the condition that TTL / f is greater than 3.0 and less than 4.5. The optical lens module provided by the utility model is small in size and simple and reliable in structure, can be mounted in a small cell detection analyzer, and can be applied to a portable cell detection analyzer, so that the scene requirements of cell analysis on site or in non-special occasions are met.

Description

Technical Field

[0001] The utility model relates to an optical lens, in particular to an optical lens module for cell counting detection and a cell counting detection device having the same. Background Art

[0002] In the fields of biomedical research and clinical testing, cell analysis plays a crucial role. This technology not only provides valuable data support for basic research but also plays a key role in evaluating the physical signs of patients. Traditionally, such analysis mainly relies on professional microscopes to complete. These high-end devices can indeed achieve complex analysis tasks such as precise observation, counting, and typing of cells, providing powerful tools for researchers and medical professionals.

[0003] However, the use of professional microscopes also faces many limitations. For example, problems such as high equipment price, large volume, and professional operation make these professional microscope devices unsuitable for cell analysis in on-site or non-special occasions. For example, in specific biomedical research, when there is no condition to bring the cell sample to be tested back to the laboratory and immediate on-site analysis is required, or when community, family, village doctors, etc. need to perform blood cell analysis in other occasions such as non-inspection departments or central laboratories.

[0004] Therefore, although the existing professional microscopes perform well in terms of accuracy and functionality, their deficiencies in portability, ease of use, and popularity seriously restrict the application and promotion of cell analysis technology in a wider range of scenarios. Summary of the Utility Model

[0005] The utility model aims to at least solve one of the technical problems in the related technologies to some extent. For this purpose, the purpose of the utility model is to provide an optical lens module for cell counting detection and a cell counting detection device having the same.

[0006] To achieve the above object, on the one hand, according to an embodiment of the utility model, the optical lens module for cell counting detection includes a first lens, a second lens, and a third lens arranged in sequence from the object side to the image side along the optical axis direction;

[0007] The first lens has a positive optical power, the object side surface of the first lens is a convex surface, and the image side surface of the first lens is a convex surface;

[0008] The second lens has a negative optical power, the object side surface of the second lens is a concave surface, and the image side surface of the second lens is a concave surface;

[0009] The third lens has a positive optical power, the object side surface of the third lens is a convex surface, and the image side surface of the third lens is a convex surface;

[0010] Among them, the total optical length TTL of the optical lens module and the effective focal length f of the optical lens module satisfy: 3.0 < TTL / f < 4.5.

[0011] In addition, the cell counting detection optical lens module according to the above embodiments of the present invention may further have the following additional technical features:

[0012] According to an embodiment of the present invention, it further includes a diaphragm, the diaphragm is arranged between the first lens and the second lens, and the aperture of the diaphragm is 1.6 mm to 2.0 mm.

[0013] According to an embodiment of the present invention, a ring plane perpendicular to the optical axis is formed around the object side surface of the second lens, and the diaphragm is attached to the ring plane.

[0014] According to an embodiment of the present invention, the effective focal length f of the optical lens module and the entrance pupil diameter EPD of the optical lens module satisfy: 3.5 < f / EPD < 4.3.

[0015] According to an embodiment of the present invention, the effective focal length f1 of the first lens and the effective focal length f of the optical lens module satisfy: 0.45 < f1 / f < 0.54.

[0016] According to an embodiment of the present invention, the effective focal length f2 of the second lens and the effective focal length f of the optical lens module satisfy: -0.36 < f2 / f < -0.29.

[0017] According to an embodiment of the present invention, the effective focal length f3 of the third lens and the effective focal length f of the optical lens module satisfy: 0.6 < f3 / f < 0.69.

[0018] On the other hand, the cell counting detection device according to the embodiment of the present invention includes a light source, an image sensor, and the cell counting detection optical lens module as described above. The light source is located on the object side of the cell counting detection optical lens module, and the image sensor is located at the imaging surface on the image side of the cell counting detection optical lens module.

[0019] The cell counting detection optical lens module and the cell counting detection device having the same according to the embodiments of the present invention can be used as an ultra-short distance microscope structure, which is small in size, simple and reliable in structure, can be installed in a small cell detection analyzer, and uses the optical lens module to project the cell image onto the image sensor. The image sensor then sends the acquired image to the calculation and processing unit inside the instrument for analysis or presents the image on the display screen. In this way, it can be applied in a portable cell detection analyzer, thereby meeting the scene requirements for cell analysis in the field or non-special occasions.

[0020] Additional aspects and advantages of the present utility model will be given in part in the following description, become apparent in part from the following description, or be understood through the practice of the present utility model. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on the structures shown in these drawings.

[0022] Figure 1 is a schematic structural diagram of the cell counting detection optical lens module according to an embodiment of the present utility model;

[0023] Figure 2 is a schematic structural diagram of the cell counting detection device according to an embodiment of the present utility model;

[0024] Figure 3 is a cross-sectional view of the cell counting detection device according to an embodiment of the present utility model.

[0025] The realization, functional features and advantages of the object of the present utility model will be further described in conjunction with the embodiments with reference to the drawings. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0026] The following will describe in detail the embodiments of the present utility model. The examples of the embodiments are shown in the drawings, where the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions throughout. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present utility model, and should not be construed as a limitation of the present utility model. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present utility model.

[0027] In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present utility model.

[0028] In addition, the terms "first" and "second" are only used for descriptive purposes and should not be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present utility model, "a plurality of" means two or more, unless otherwise specifically defined.

[0029] In the present utility model, unless otherwise clearly specified and defined, terms such as "mounted", "connected", "coupled", "fixed", etc. should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0030] In the present utility model, unless otherwise clearly specified and defined, the first feature being "above" or "below" the second feature may include the first and second features being in direct contact, or may include the first and second features not being in direct contact but being in contact through additional features therebetween. Moreover, the first feature being "above", "over" and "on top of" the second feature includes the first feature being directly above and obliquely above the second feature, or merely indicating that the first feature has a higher horizontal height than the second feature. The first feature being "below", "beneath" and "underneath" the second feature includes the first feature being directly below and obliquely below the second feature, or merely indicating that the first feature has a lower horizontal height than the second feature.

[0031] The cell counting detection optical lens module of the embodiment of the present utility model and the cell counting detection device having the same will be described in detail below with reference to the accompanying drawings.

[0032] Referring to Figure 1 As shown, the cell counting detection optical lens module according to the embodiment of the present utility model includes a first lens 10, a second lens 20, and a third lens 30 arranged in sequence from the object side to the image side along the optical axis direction.

[0033] Specifically, the first lens 10 has a positive focal power. The object side surface S10 of the first lens 10 is a convex surface, and the image side surface S11 of the first lens 10 is a convex surface, which helps to collect and focus the light from the sample to be detected. The first lens 10 is located on the object side and is used to provide good incident conditions for the subsequent optical path.

[0034] The second lens 20 has a negative optical power. The object side surface S20 of the second lens 20 is concave, and the image side surface S21 of the second lens 20 is concave. That is to say, the second lens 20 is located at the middle position, and both its object side surface S20 and image side surface S21 are concave. This second lens 20 is used to adjust the optical path, effectively reducing aberration, and at the same time also plays a role in shortening the overall optical length of the optical lens module.

[0035] The third lens 30 has a positive optical power. The object side surface S30 of the third lens 30 is convex, and the image side surface S31 of the third lens 30 is convex. That is to say, this third lens 30 is located on the image side, and both its object side surface S30 and image side surface S31 are convex. The function of the third lens 30 is to further focus the light to form a clear final image.

[0036] Among them, the overall optical length TTL of the optical lens module and the effective focal length f of the optical lens module satisfy: 3.0 < TTL / f < 4.5.

[0037] The advantage of this three-lens structure is that while ensuring the imaging quality, it significantly shortens the overall optical length of the optical lens module. Moreover, the proportional relationship between the overall optical length TTL and the effective focal length f makes it satisfy the condition of 3.0 < TTL / f < 4.5. The setting of this proportional relationship ensures that the optical lens module can not only maintain a short object distance (i.e., the distance between the first lens 10 and the sample to be measured), but also maintain sufficient magnification and imaging quality.

[0038] The design of the optical lens module of the present utility model enables it to be applied as an ultra-short distance microscope structure in a portable cell detection analyzer. Compared with traditional microscopes, this structure has the characteristics of small size, simple and reliable structure. It can be easily integrated into a small cell detection analyzer, and high-quality cell image acquisition can be achieved without a complex optical system.

[0039] In practical applications, this optical lens module projects the image of the cell sample onto the image sensor. The image data captured by the image sensor can then be transmitted to the computing and processing unit inside the instrument for further analysis, or directly presented on the display screen of the device. This design makes the entire cell analysis process efficient and convenient, greatly expanding the application scenarios of cell analysis technology, making a portable cell detection analyzer possible, and thus meeting the needs of cell analysis in on-site or non-special occasions. For example, it can be used in scenarios such as field scientific research investigations, community medical examinations, and home health monitoring, providing a flexible and efficient cell analysis tool for biomedical researchers and medical workers.

[0040] According to the cell counting detection optical lens module provided by the embodiments of the present utility model, it can be used as an ultra-short distance microscope structure, which is small in size, simple and reliable in structure, and can be installed in a small cell detection analyzer. The optical lens module projects the cell image onto the image sensor, and the image sensor then sends the acquired image to the calculation and processing unit inside the instrument for analysis or presents the image on the display screen. In this way, it can be realized in a portable cell detection analyzer application, so as to meet the scenario requirements of cell analysis in the field or non-special occasions.

[0041] In some embodiments of the present utility model, the optical lens module further includes a diaphragm 40, the diaphragm 40 is arranged between the first lens 10 and the second lens 20, and the aperture of the diaphragm 40 is 1.6 mm to 2.0 mm.

[0042] In this embodiment, by introducing the diaphragm 40, the amount of light entering the optical lens module can be effectively controlled. By selecting the aperture range of 1.6 mm to 2.0 mm, the diaphragm 40 can effectively block the marginal light. By controlling the amount of light, while ensuring sufficient brightness, the clarity and contrast of the image can be significantly improved. This is particularly important for cell observation, because clear boundaries and good contrast can greatly improve the accuracy of cell counting and analysis. In addition, placing the diaphragm 40 between the first lens 10 and the second lens 20 can ensure that the diaphragm 40 can play a role at a key position in the optical path. At this position, the diaphragm 40 can not only effectively control the light, but also cooperate with the designs of the first lens 10 and the second lens 20 to further optimize the optical performance of the entire optical path.

[0043] Preferably, a circular plane S22 perpendicular to the optical axis is formed around the object side surface of the second lens 20, and the diaphragm 40 is attached to the circular plane S22.

[0044] By directly attaching the diaphragm 40 to the circular plane S22 of the second lens 20, on the one hand, the reliability and stability of the installation of the diaphragm 40 are ensured, and the risk of displacement or deformation of the diaphragm 40 during use is greatly reduced. On the other hand, the diaphragm 40 attached to the circular plane S22 of the second lens 20 completely blocks the marginal light of optical interference from entering the second lens 20, which helps to further improve the contrast and clarity of the image.

[0045] In an embodiment of the present utility model, the effective focal length f of the optical lens module and the entrance pupil diameter EPD of the optical lens module satisfy: 3.5 < f / EPD < 4.3.

[0046] In this embodiment, the ratio of the effective focal length f of the optical lens module to the entrance pupil diameter EPD of the optical lens module is selected in the range of 3.5 < f / EPD < 4.3. This range of selection ensures both sufficient light passing rate and good resolution and appropriate depth of field. Specifically, when the ratio is between 3.5 and 4.3, it ensures that the optical lens module has sufficient light collection ability. At the same time, it can also provide high resolution. In cell observation, the structure and boundary of cells can be clearly distinguished, which is beneficial to accurate cell counting and analysis. This range provides an appropriate depth of field, and clear images can still be obtained when observing samples that are not completely flat. In addition, this range helps to control optical aberrations such as spherical aberration and chromatic aberration, thereby improving the overall image quality.

[0047] In an embodiment of the present utility model, the effective focal length f1 of the first lens 10 and the effective focal length f of the optical lens module satisfy: 0.45 < f1 / f < 0.54. This proportional range ensures that the first lens 10 plays an important role in the optical lens module, not only improving the light collection ability and aberration control, but also optimizing the compactness of the optical lens module structure and the working distance. At the same time, it provides flexible control for the magnification, enabling the optical lens module to cover a sufficiently large field of view while maintaining high resolution.

[0048] In an embodiment of the present utility model, the effective focal length f2 of the second lens 20 and the effective focal length f of the optical lens module satisfy: -0.36 < f2 / f < -0.29.

[0049] By designing the second lens 20 as a negative focal length element, effective compensation and balance of the positive focal power of the first lens 10 are achieved. This configuration not only helps to control the overall aberration, especially spherical aberration and field curvature, but also significantly shortens the total optical length of the optical lens module, improving the compactness of the system. At the same time, the second lens 20 with negative focal length provides greater flexibility for the entire optical path, which is beneficial to optimizing the beam path and adjusting the magnification. In addition, the ratio of f2 / f is controlled between -0.36 and -0.29, ensuring that the optical lens module has good manufacturing feasibility and cost-effectiveness while maintaining high optical performance.

[0050] In an embodiment of the present utility model, the effective focal length f3 of the third lens 30 and the effective focal length f of the optical lens module satisfy: 0.6 < f3 / f < 0.69. The third lens 30, as a positive focal length element, has a focal length slightly greater than that of the first lens 10. This configuration not only effectively compensates for the aberrations introduced by the first lens 10 and the second lens 20, especially spherical aberration and coma aberration, but also provides the necessary positive optical power for the entire optical lens module, ensuring good imaging quality. At the same time, this design also helps to control the divergence of the light beam, optimizes the back focal length of the optical lens module, enabling the imaging plane to better match the image sensor. In addition, the precise control of the f3 / f ratio within the range of 0.6 to 0.69 is also beneficial for adjusting the magnification and working distance, enhancing the adaptability of the optical lens module under different observation conditions.

[0051] Exemplarily, the overall optical length TTL of the optical lens module is 31.1 mm, the entrance pupil diameter EPD is 2.1 mm, the effective focal length f of the optical lens module is 8.23 mm, the effective focal length f1 of the first lens 10 is 4.2 mm, the effective focal length f2 of the second lens 20 is -2.65 mm, the effective focal length f3 of the third lens 30 is 5.3 mm, and the ratio of the overall optical length of the optical lens module to the effective focal length of the optical lens module TTL / f = 31.1 / 8.23 = 3.78 mm.

[0052] Referring to Figures 2 to 3 As shown in the figure, the embodiment of the present utility model also provides a cell counting detection device, including a light source 50, an image sensor 60, and the cell counting detection optical lens module as described above. The light source 50 is located on the object side of the cell counting detection optical lens module, and the image sensor 60 is located at the imaging plane on the image side of the cell counting detection optical lens module.

[0053] During detection, a sample (blood sample) can be placed on a slide 70, and the slide 70 is placed in the light output direction of the light source 50. The light of the light source 50 passes through the slide 70 and successively passes through the first lens 10, the aperture 40, the second lens 20, and the third lens 30, and then forms an image on the image sensor 60 and is recorded by the image sensor 60. The formed image is an image of the white blood cells in the blood sample after staining magnified by the optical lens module. The number of white blood cells can be distinguished within the field of view of the image, and the data structure can be calculated through the processing unit of the system, realizing the detection of white blood cell counting.

[0054] According to the cell counting detection device provided by the embodiments of the present utility model, it has the above-mentioned cell counting detection optical lens module. This optical lens module can be used as an ultra-short distance microscope structure, which is small in size, simple and reliable in structure, and can be installed in a small cell detection analyzer. The optical lens module projects the cell image onto the image sensor 60, and the image sensor 60 then sends the acquired image to the calculation and processing unit inside the instrument for analysis or presents the image on the display screen. In this way, it can be applied in a portable cell detection analyzer, thus meeting the scenario requirements for cell analysis in on-site or non-special occasions.

[0055] In the description of this specification, the description with reference to terms such as "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in a suitable manner in any one or more embodiments or examples. In addition, without contradiction, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0056] The above are only the preferred embodiments of the present utility model, and do not limit the patent scope of the present utility model accordingly. Any equivalent structural transformation made under the inventive concept of the present utility model by using the content of the specification and drawings of the present utility model, or direct / indirect application in other related technical fields, is included in the patent protection scope of the present utility model.

Claims

1. An optical lens module for cell counting detection, characterized in that, It includes a first lens, a second lens, and a third lens arranged in sequence from the object side to the image side along the optical axis direction; The first lens has a positive optical power, the object side surface of the first lens is convex, and the image side surface of the first lens is convex; The second lens has a negative optical power, the object side surface of the second lens is concave, and the image side surface of the second lens is concave; The third lens has a positive optical power, the object side surface of the third lens is convex, and the image side surface of the third lens is convex; Wherein, the total optical length TTL of the optical lens module and the effective focal length f of the optical lens module satisfy: 3.0 < TTL / f < 4.

5.

2. The cell counting detection optical lens module according to claim 1, characterized in that, It further includes a diaphragm, the diaphragm is arranged between the first lens and the second lens, and the aperture of the diaphragm is 1.6 mm to 2.0 mm.

3. The cell counting detection optical lens module according to claim 2, wherein A ring-shaped plane perpendicular to the optical axis is formed around the periphery of the object side surface of the second lens, and the diaphragm is attached to the ring-shaped plane.

4. The cell counting detection optical lens module according to claim 1, characterized in that, The effective focal length f of the optical lens module and the entrance pupil diameter EPD of the optical lens module satisfy: 3.5 < f / EPD < 4.

3.

5. The cell counting detection optical lens module according to claim 1, characterized in that, The effective focal length f1 of the first lens and the effective focal length f of the optical lens module satisfy: 0.45 < f1 / f < 0.

54.

6. The cell counting detection optical lens module according to claim 1, wherein The effective focal length f2 of the second lens and the effective focal length f of the optical lens module satisfy: -0.36 < f2 / f < -0.

29.

7. The cell counting detection optical lens module according to claim 1, wherein The effective focal length f3 of the third lens and the effective focal length f of the optical lens module satisfy: 0.6 < f3 / f < 0.

69.

8. A cell counting detection device, characterized in that, It includes a light source, an image sensor, and the cell counting detection optical lens module according to any one of claims 1 to 7, the light source is located on the object side of the cell counting detection optical lens module, and the image sensor is located at the imaging surface on the image side of the cell counting detection optical lens module.

Images