Sleep deprivation experiment device

Abstract

The utility model relates to the technical field of test devices, and discloses a sleep deprivation test device, which comprises a box body, wherein a cover is arranged at the top of the box body; the feeding trough is arranged in the box body; a lifting assembly is arranged in the box body, and the lifting assembly comprises a plate body arranged in the box body; the rotating rod is rotationally arranged in the box body; the extrusion block is fixedly arranged on the outer side wall of the rotating rod; according to the test device, the motor is used for driving the rotating rod to rotate through the lifting assembly, so that the extrusion block extrudes the stand column to ascend and descend and drives the platform to ascend and descend, and the laboratory mouse on the platform can be kept awake so as to observe the state of the mouse. And compared with the existing device, the sleep of the laboratory mouse can be better influenced. According to the test device, through the design of the protection assembly and the inclined plate, the laboratory mouse can climb to the platform faster along the inclined plate after falling into water, and it is avoided that the laboratory mouse drowns in water for a long time to affect experimental data.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental devices, in particular to a sleep deprivation experimental device. Background Art

[0002] Currently, at least one-tenth of the world's population suffers from neuropsychiatric disorders, resulting in trillions of dollars in medical expenses each year. The increasing incidence of neuropsychiatric diseases not only places a heavy burden on patients and society, but also poses unprecedented challenges to the treatment and research of these diseases. Against this backdrop, brain science has become one of the hot topics in international scientific research today. In brain science research, the most commonly used experimental animals are mice and rats (hereinafter referred to as laboratory mice). Conducting behavioral experiments on laboratory mice and observing their behavior is an important method in brain science research.

[0003] China's utility model CN221128382U experimental mouse water platform sleep deprivation box device has designed an experimental device. Its principle is to add water inside the box, and then set up columns inside the box. The experimental mouse is placed on the columns inside the box, so that the experimental mouse can only stay on the columns. If it moves, it will fall into the water, thereby affecting the mouse's sleep.

[0004] However, the existing device has fixed columns, which allow mice to sleep on them. This device cannot completely affect the mice's sleep, thus affecting the experimental data. Therefore, a vibrating platform was designed to address the above issues and affect the sleep of experimental mice. Utility Model Content

[0005] (1) Technical problems solved

[0006] In view of the shortcomings of the existing technology, the utility model provides a sleep deprivation experimental device, which has the advantage of having a stronger impact on mice and preventing them from sleeping, and solves the problem that the existing device cannot completely prevent mice from sleeping.

[0007] (2) Technical solution

[0008] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a sleep deprivation experimental device, comprising: a box with a lid on the top; a food trough arranged inside the box; a lifting assembly arranged inside the box, the lifting assembly comprising: a plate arranged inside the box; a rotating rod rotatably arranged inside the box; an extrusion block fixedly arranged on the outer side wall of the rotating rod; a motor arranged on the outer side wall of the box, and an output shaft of the motor inserted into the box and connected to the rotating rod; a bottom end of a cylinder passing through the plate and fixedly connected to the plate; a column arranged inside the cylinder; and a platform arranged on the top of the column.

[0009] In some embodiments, the box body and the cover are both made of transparent materials.

[0010] In some embodiments, the lifting assembly further includes: a ball disposed at the bottom of the column.

[0011] In some embodiments, the lifting assembly further includes: a spring symmetrically arranged on the top of the plate body, and the top end of the spring is connected to the platform.

[0012] In some embodiments, the lifting assembly further includes: a tube body sleeved on the outer wall of the spring, with a bottom end connected to the plate body, and a height consistent with that of the cylinder body.

[0013] In some embodiments, the lifting assembly further includes: a rubber pad disposed at the bottom of the platform.

[0014] In some embodiments, a protective component is provided inside the box, and the protective component includes: vertical plates symmetrically arranged on both sides of the platform; inclined plates symmetrically arranged on the inner wall of the box; and multiple holes are provided, all of which are opened on the top of the inclined plates.

[0015] In some embodiments, the protective component further includes: a convex strip disposed on the top of the platform.

[0016] (3) Beneficial effects

[0017] Compared with the prior art, the present invention provides a sleep deprivation experimental device with the following beneficial effects:

[0018] 1. This test device uses a motor-driven rotating rod in the lifting assembly to rotate, causing the squeezing block to move up and down, and in turn, the platform to move up and down. This allows the laboratory mice on the platform to stay awake and observe their condition. Compared with existing devices, this device can better influence the sleep of laboratory mice.

[0019] 2. The test device, through the design of the protective component inclined plate, can enable the experimental mice to climb to the platform faster along the inclined plate after falling into the water, avoiding drowning in the water for a long time and affecting the experimental data. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a schematic diagram of the structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the structure inside the box of the utility model;

[0022] Figure 3 This is a schematic diagram of the structure of the connection between the inclined plate and the box body of the utility model;

[0023] Figure 4 It is a schematic diagram of the structure inside the cylinder and tube body of the utility model.

[0024] In the figure: 11, box body; 12, lid; 13, trough;

[0025] 2. Lifting assembly; 21. Plate; 22. Rotating rod; 23. Extrusion block; 24. Motor; 25. Cylinder; 26. Column; 261. Ball; 27. Platform; 28. Spring; 281. Tube; 29. ​​Rubber pad; 3. Protective assembly; 31. Vertical plate; 32. Inclined plate; 33. Hole; 34. Raised strip. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0027] It should be noted that all directional indications in the embodiments of the present application are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.

[0028] In this application, unless otherwise specified or limited, the terms "connection" and "fixation" should be understood in a broad sense. For example, "fixation" can mean fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two elements or interaction between two elements, unless otherwise specified. For those skilled in the art, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0029] In addition, the descriptions of "first", "second", etc. in this application are for descriptive purposes only and should not be understood as indicating or implying their relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined as "first" or "second" may explicitly or implicitly include at least one of such features. In addition, the technical solutions between the various embodiments can be combined with each other, but this must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0030] Currently, at least one-tenth of the world's population suffers from neuropsychiatric disorders, resulting in trillions of dollars in medical expenses each year. The increasing incidence of neuropsychiatric diseases not only places a heavy burden on patients and society, but also poses unprecedented challenges to the treatment and research of these diseases. Against this backdrop, brain science has become one of the hot topics in international scientific research today. In brain science research, the most commonly used experimental animals are mice and rats (hereinafter referred to as laboratory mice). Conducting behavioral experiments on laboratory mice and observing their behavior is an important method in brain science research.

[0031] In related technologies, water is added to a chamber, and then vertical columns are installed inside the chamber. Laboratory mice are placed on these columns, forcing the mice to stay on the columns. Any movement would cause them to fall into the water, disrupting their sleep. However, the columns in existing devices are fixed, allowing mice to sleep on them. This device does not fully disrupt their sleep, thus affecting experimental data.

[0032] In order to solve the problems in the related art to a certain extent, the embodiment of the present application provides a sleep deprivation experimental device. When the experiment is needed, water needs to be added to the inside of the box 11 to a position not far below the top of the cylinder 25, and then food and water need to be added to the inside of the trough 13. Finally, the lid 12 is closed. At this time, it is only necessary to connect the motor 24 to the external power supply. The motor 24 will drive the rotating rod 22 to drive the extrusion block 23 to rotate. During the rotation, the column 26 will be squeezed to move upward. The column 26 will move downward due to its own gravity and fit into the extrusion block 23. Therefore, during the rotation of the extrusion block 23, the column 26 is pushed up and down. At this time, the platform 27 also moves up and down, making it impossible for the experimental mouse to lie stably on the platform 27, thereby stimulating the experimental mouse to stay alert and avoid falling into the water, which can effectively affect the sleep of the experimental mouse.

[0033] The present application is described below with reference to specific embodiments and with reference to the accompanying drawings:

[0034] Combine Figures 1-4 The embodiment of the present application provides a sleep deprivation experimental device, comprising: a box body 11 with a lid 12 on the top; a food trough 13 arranged inside the box body 11; a lifting assembly 2 arranged inside the box body 11, and the lifting assembly 2 comprises: a plate body 21 arranged inside the box body 11; a rotating rod 22 rotatably arranged inside the box body 11; an extrusion block 23 fixedly arranged on the outer side wall of the rotating rod 22; a motor 24 arranged on the outer side wall of the box body 11, and the output shaft is inserted into the inside of the box body 11 and connected to the rotating rod 22; the bottom end of a cylinder body 25 passes through the plate body 21 and is fixedly connected to the plate body 21; a column 26 is arranged inside the cylinder body 25; and a platform 27 is arranged on the top of the column 26.

[0035] During use, when a test is needed, first water needs to be added to the inside of the box 11 to a position not far below the top of the cylinder 25, and then food and water need to be added to the inside of the trough 13, and finally the lid 12 needs to be closed. At this time, it is only necessary to connect the motor 24 to the external power supply. The motor 24 will drive the rotating rod 22 to rotate the squeezing block 23. During the rotation, the column 26 will be squeezed to move upward. The column 26 will move downward due to its own gravity and fit into the squeezing block 23. As the squeezing block 23 rotates, the column 26 is pushed up and down. At this time, the platform 27 also moves up and down, making it impossible for the experimental mouse to lie stably on the platform 27, thereby stimulating the experimental mouse to stay alert and avoid falling into the water, which can effectively affect the sleep of the experimental mouse.

[0036] In some embodiments, the box body 11 and the cover 12 are both made of transparent materials.

[0037] The transparent material design is conducive to observing the status of experimental mice during use, thereby recording experimental data.

[0038] In some embodiments, the lifting assembly 2 further includes a ball 261 disposed at the bottom of the column 26 .

[0039] The design of the ball bearing 261 can reduce the friction between the column 26 and the extrusion block 23 during use.

[0040] In some embodiments, the lifting assembly 2 further includes: a spring 28 symmetrically arranged on the top of the plate 21 , and the top end of the spring is connected to the platform 27 .

[0041] During use, the spring 28 is designed to pull the platform 27 downward so that the bottom end of the column 26 always fits against the outer side wall of the extrusion block 23.

[0042] In some embodiments, the lifting assembly 2 further includes: a tube 281 sleeved on the outer wall of the spring 28 , with the bottom end connected to the plate 21 , and the height thereof being consistent with that of the cylinder 25 .

[0043] When in use, the design of the tube body 281 can wrap the spring 28 inside, and at the same time, the height is consistent with the cylinder 25 to prevent water from contacting the spring 28, thereby better protecting the spring 28.

[0044] In some embodiments, the lifting assembly 2 further includes a rubber pad 29 disposed at the bottom of the platform 27 .

[0045] The design of the rubber pad 29 can mitigate the impact between the platform 27 and the cylinder 25 during use, thereby better protecting the platform 27 and reducing the noise generated by the impact.

[0046] In some embodiments, a protective component 3 is provided inside the box 11, and the protective component 3 includes: vertical plates 31 symmetrically arranged on both sides of the platform 27; inclined plates 32 symmetrically arranged on the inner wall of the box 11; and multiple holes 33 are provided, all of which are opened at the top of the inclined plates 32.

[0047] During use, after the experimental mouse falls into the water from the platform 27, it falls onto the inclined plate 32. At this time, due to the holes 33 provided on the inclined plate 32, the water floods the inclined plate 32 through the holes 33. At this time, the mouse can climb back onto the platform 27 along the inclined plate 32. At the same time, the design of the vertical plate 31 can prevent the experimental mouse from falling under the inclined plate 32.

[0048] In some embodiments, the protection component 3 further includes: a ridge 34 disposed on the top of the platform 27 .

[0049] During use, the ridges 34 can increase the friction on the platform 27 so that the experimental mouse can hold on tightly and reduce the possibility of falling.

[0050] In the description of this specification, the reference terms "one embodiment", "some embodiments", "example", "specific example", "some examples", etc. mean that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic expressions of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art can combine and combine different embodiments or examples described in this specification.

[0051] In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the fact that ordinary technicians in this field can implement them. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0052] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A sleep deprivation experimental device, comprising: A box body (11) is provided with a cover (12) on the top; A feeding trough (13) is arranged inside the box (11); The invention is characterized in that a lifting assembly (2) is provided inside the box (11), and the lifting assembly (2) comprises: A plate (21) is arranged inside the box (11); A rotating rod (22) is rotatably arranged inside the box (11); An extrusion block (23) is fixedly arranged on the outer side wall of the rotating rod (22); A motor (24) is arranged on the outer wall of the box (11), and an output shaft is inserted into the interior of the box (11) and connected to the rotating rod (22); A cylinder (25), the bottom end of which passes through the plate (21) and is fixedly connected to the plate (21); A column (26) is arranged inside the cylinder (25); A platform (27) is arranged on the top of the column (26).

2. A sleep deprivation experimental device according to claim 1, characterized in that: The box body (11) and the cover (12) are both designed with transparent materials.

3. The sleep deprivation experimental device according to claim 1, characterized in that: The lifting assembly (2) further comprises: The ball (261) is arranged at the bottom of the column (26).

4. The sleep deprivation experimental device according to claim 1, characterized in that: The lifting assembly (2) further comprises: The spring (28) is symmetrically arranged on the top of the plate body (21), and the top end is connected to the platform (27).

5. The sleep deprivation experimental device according to claim 4, characterized in that: The lifting assembly (2) further comprises: The tube body (281) is sleeved on the outer wall of the spring (28), and the bottom end is connected to the plate body (21), and the height is consistent with that of the cylinder body (25).

6. The sleep deprivation experimental device according to claim 1, characterized in that: The lifting assembly (2) further comprises: A rubber pad (29) is arranged on the bottom of the platform (27).

7. The sleep deprivation experimental device according to claim 1, characterized in that: A protective component (3) is provided inside the box (11), and the protective component (3) comprises: Vertical plates (31) are symmetrically arranged on both sides of the platform (27); An inclined plate (32) is symmetrically arranged on the inner side wall of the box body (11); There are a plurality of holes (33), all of which are opened on the top of the inclined plate (32).

8. The sleep deprivation experimental device according to claim 7, characterized in that: The protection component (3) further comprises: The convex strip (34) is arranged on the top of the platform (27).

Images