Hematopoietic stem cell blood bag cryopreservation box

By designing a hematopoietic stem cell cryopreservation box with fixing plates and clamps, the problems of shaking and scratching of blood bags during cryopreservation are solved, achieving stable storage and convenient operation, and reducing storage costs.

CN223987605UActive Publication Date: 2026-03-13SHANDONG YISHENGHE BIOMEDICAL CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-17
Publication Date
2026-03-13

AI Technical Summary

Technical Problem

Existing hematopoietic stem cell cryopreservation boxes are prone to shaking during transportation and handling, which can lead to damage to the blood bags and leakage of contents. In addition, the round holes in the cryopreservation boxes can easily scratch the blood bags.

Method used

A hematopoietic stem cell cryopreservation box was designed, which includes a protective box, a lid, a freezing chamber and a placement chamber. The blood bag is fixed with a fixing plate and a clamp, and combined with materials with good thermal conductivity and an insulation pad, it ensures that the blood bag is stored stably in a low-temperature environment.

Benefits of technology

It effectively prevents blood bags from shaking and being scratched, extends storage time, reduces storage costs, and improves the convenience and safety of retrieval.

✦ Generated by Eureka AI based on patent content.

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  • Figure CN223987605U_ABST
    Figure CN223987605U_ABST
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Abstract

The utility model discloses a hematopoietic stem cell blood bag cryopreservation box, and relates to the technical field of blood bag cryopreservation boxes, the hematopoietic stem cell blood bag cryopreservation box comprises a protection box, a freezing cavity and a placing cavity are arranged in the protection box, a baffle plate is arranged between the freezing cavity and the placing cavity, the surface of the baffle plate is provided with through holes, and the through holes are communicated with the freezing cavity and the placing cavity. A plate groove is fixedly connected to the side wall of the containing cavity, a fixing plate is inserted into the plate groove, mounting blocks are arranged at the two ends of the containing cavity, movable cavities are formed in the mounting blocks in the vertical direction in a penetrating mode, and clamping plates are arranged in the movable cavities. The blood bag in the containing cavity is attached and fixed through the fixing plate, the two clamping plates clamp the sealing edge of the blood bag, the fixing plate is matched, the blood bag is further protected, shaking is reduced, and damage is avoided.
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Description

Technical Field

[0001] This utility model belongs to the technical field of blood bag cryopreservation boxes, specifically, it relates to a hematopoietic stem cell blood bag cryopreservation box. Background Technology

[0002] Hematopoietic stem cells are adult stem cells in the blood system. They are a heterogeneous population with the ability to self-renew for a long time and the potential to differentiate into various mature blood cells. They are of great significance in medical treatment and research. The blood bags storing hematopoietic stem cells are often cryopreserved by passing liquid nitrogen through a cryopreservation box.

[0003] Chinese patent CN210338964U discloses a liquid nitrogen cryopreservation box for hematopoietic stem cell blood bags, including a box body and a box lid hinged by a pivot. The upper surface of the box body has a box body cavity, in which a first baffle and a cryopreservation box are arranged sequentially from bottom to top. A groove is formed in the middle of the outer side wall of the box body away from the pivot. The lower surface of the box lid has a box lid cavity, in which a second baffle is arranged. A protrusion is formed in the middle of the inner side wall of the box lid away from the pivot, and a handle is formed in the middle of the outer side wall of the box lid away from the pivot. In the above-mentioned prior art, when the finished blood bag is placed in the cryopreservation box, the blood bag is not fixed. When the cryopreservation box is taken out and transferred, the blood bag will shake inside the cryopreservation box. The bag body is easy to open and cause leakage of contents. At the same time, the bag body is also easy to come into contact with the round hole on the cryopreservation box. The relatively sharp round hole can easily scratch the blood bag and cause damage to the blood bag.

[0004] In view of this, this utility model is hereby proposed. Utility Model Content

[0005] The technical problem to be solved by this utility model is to overcome the shortcomings of the prior art and provide a hematopoietic stem cell blood bag cryopreservation box, which solves the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by this utility model is as follows:

[0007] A hematopoietic stem cell cryopreservation box includes: a protective box, characterized in that the protective box is provided with a box cover on the top, the protective box has a freezing chamber and a placement chamber inside, a baffle is provided between the freezing chamber and the placement chamber, the surface of the baffle is provided with a through hole, a plate groove is fixedly connected to the side wall of the placement chamber, and a fixing plate is inserted into the plate groove.

[0008] Optionally, mounting blocks are provided at both ends of the placement cavity, and the mounting blocks have a movable cavity through which they are opened vertically. A clamping plate is provided inside the movable cavity. A circular hole is opened horizontally through the mounting blocks near the center position. A spring post is provided on the clamping plate at the position of the circular hole, and a spring is sleeved on the surface of the spring post.

[0009] Optionally, the movable cavity has an inner groove near the center in the vertical direction, and the middle part of the clamping plate is embedded in the inner groove.

[0010] Optionally, an insulation pad is provided inside the lid.

[0011] Optionally, the top of the clamping plate is chamfered.

[0012] Optionally, the fixing plate is made of a material with good thermal conductivity.

[0013] By adopting the above technical solution, this utility model has the following beneficial effects compared with the prior art. Of course, any product implementing this utility model does not necessarily need to achieve all of the following advantages at the same time:

[0014] 1. This hematopoietic stem cell cryopreservation box uses refrigerant in the freezing chamber to cool the blood bag. The blood bag inside the chamber is fixed in place by a fixing plate to prevent it from being scratched by contact with the perforation. The refrigerant absorbs the temperature of the fixing plate, and the fixing plate is in contact with the blood bag to cool it down, thereby extending the storage time of the blood bag and reducing storage costs.

[0015] 2. This hematopoietic stem cell cryopreservation box uses two clamps to hold the edge of the blood bag seal, along with a fixing plate, to further protect the blood bag, reduce shaking, and prevent damage. The two clamps can be opened by inserting a finger into the chamfered top, making it easier to fix and retrieve the blood bag.

[0016] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings. Attached Figure Description

[0017] The accompanying drawings described below are merely some embodiments. Those skilled in the art can obtain other drawings based on these drawings without any creative effort.

[0018] In the picture:

[0019] Figure 1 This is a schematic diagram of the structure of this utility model;

[0020] Figure 2 This is a top view of the present invention;

[0021] Figure 3 for Figure 2 The sectional view shown is taken at point A, with the cutting line visible.

[0022] Figure 4 for Figure 2 The sectional view at point B is shown.

[0023] Figure 5 This is a schematic diagram of the mounting block and clamping plate of this utility model.

[0024] The attached diagram lists the components represented by each number as follows:

[0025] 1. Protective box; 101. Box cover; 102. Baffle; 103. Through hole; 2. Freezing chamber; 3. Placement chamber; 4. Fixing plate; 401. Plate groove; 5. Mounting block; 501. Movable chamber; 502. Inner groove; 503. Round hole; 6. Clamping plate; 601. Spring post; 602. Spring.

[0026] It should be noted that these accompanying drawings and textual descriptions are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention to those skilled in the art by referring to specific embodiments. Detailed Implementation

[0027] The present invention will now be described in further detail with reference to the accompanying drawings.

[0028] Please see Figure 1-5 As shown, this embodiment provides a hematopoietic stem cell blood bag cryopreservation box, including: a protective box 1.

[0029] like Figure 1 As shown, the protective box 1 in this embodiment has a lid 101 on top. The protective box 1 has a freezing chamber 2 and a placement chamber 3 inside. A baffle 102 is provided between the freezing chamber 2 and the placement chamber 3. A through hole 103 is provided on the surface of the baffle 102. A plate groove 401 is fixedly connected to the side wall of the placement chamber 3, and a fixing plate 4 is inserted into the plate groove 401. The lid 101 and the protective box 1 are rotatably connected. Rotating the lid 101 opens the protective box 1, and a blood bag is placed in the placement chamber 3. Refrigerant is placed in the freezing chamber 2. The placement chamber 3 and... The freezing chamber 2 is separated by a baffle 102. The refrigerant absorbs the heat in the placement chamber 3 through the perforation 103 to cool the blood bag, keeping it at a low temperature and extending its storage time. The two fixing plates 4 in the placement chamber 3 are bent inward and installed on the placement chamber 3 by inserting them into the plate groove 401. This reduces the space of the placement chamber 3 to support the blood bag, so that the blood bag inside is less shaken when the user takes out the protective box 1. At the same time, it prevents the blood bag from contacting the perforation 103 on the baffle 102 and prevents the edge of the perforation 103 from scratching the bag.

[0030] like Figure 2 , 3As shown in Figure 4, in this embodiment, mounting blocks 5 are provided at both ends of the placement cavity 3. The mounting blocks 5 have a movable cavity 501 extending vertically through them. A clamping plate 6 is provided inside the movable cavity 501. A circular hole 503 is provided horizontally through the mounting blocks 5 near the center. A spring post 601 is provided at the position of the circular hole 503 on the clamping plate 6. A spring 602 is sleeved on the surface of the spring post 601. The clamping plate is L-shaped. The two clamping plates close towards the middle of the movable cavity 501 to hold the sealing position of the blood bag. With the fit of the fixing plate 4, the blood bag is completely fixed to prevent movement and damage to the bag. The clamping plate 6 is inserted into the corresponding circular hole 503 on the mounting block 5 through the spring post 601 in the middle position. The two ends of the spring 602 rest on the mounting block 5 and the clamping plate 6. The spring 602 applies force to push the two clamping plates 6 towards the center to hold the blood bag.

[0031] like Figure 2 , 3 As shown, in this embodiment, the movable cavity 501 has an inner groove 502 near the center in the vertical direction, and the middle part of the clamping plate 6 is embedded in the inner groove 502; wherein, the middle part of the clamping plate 6 on the side of the movable cavity 501 protrudes forward by a section and is inserted into the inner groove 502. The clamping plate 6 will not easily fall out of the movable cavity 501 by the limiting of the inner groove 502, and the clamping plate 6 can be repeatedly pushed without being damaged, thus extending the service life of the entire protective box 1.

[0032] like Figure 1 As shown, the box cover 101 in this embodiment is provided with an insulation pad inside; wherein, the insulation pad is adhered to the top of the box cover 101, and when the box cover 101 is closed, it seals the entire placement cavity 3 and the movable cavity 501, reducing the external temperature from entering the protective box 1, extending the internal temperature rise time, and improving the insulation effect of the protective box 1.

[0033] like Figure 5 As shown, the top of the clamp 6 in this embodiment is chamfered; when the two baffles 102 are in contact, the two chamfers form a groove. When the user needs to take out or put in the blood bag, he can open the two baffles 102 by inserting his fingers into the groove and pushing them down. The separation of the baffles 102 is relatively quick and effortless. At this time, the blood bag seal is placed between the two baffles 102, and the user releases his hand. The spring 602 applies force to the two baffles 102 to fix the blood bag in place.

[0034] like Figure 1 As shown, the fixing plate 4 in this embodiment is made of a material with good thermal conductivity. The blood bag and the refrigerant in the freezing chamber 2 are isolated by the fixing plate 4. The temperature of the blood bag is first absorbed by the fixing plate 4 and then by the refrigerant. Therefore, the fixing plate 4 needs to have good thermal conductivity to quickly transfer heat so that the blood bag can cool down quickly.

[0035] Working principle: Rotate to open the lid 101, put refrigerant into the freezing chamber 2, and put the blood bag into the placement chamber 3. The two sides of the blood bag are fixed together by the pre-inserted fixing plates 4. Insert your fingers into the chamfered position of the two clamps 6 to separate the two clamps 6. Insert the sealing end of the blood bag between the two clamps 6, and then release the clamps 6. The two clamps 6 will close quickly by the force of the spring 602 to hold the blood bag. With the help of the fixing plates 4, the blood bag is fixed. Blood bags can be installed in multiple placement chambers 3 and at both ends of the mounting blocks 5. After installation, close the lid 101 to seal.

[0036] This utility model is not limited to the above-described embodiments. Anyone should know that structural changes made under the guidance of this utility model, and any technical solutions that are the same as or similar to this utility model, fall within the protection scope of this utility model. Technical aspects, shapes, and structures not described in detail in this utility model are all publicly known technologies.

Claims

1. A hematopoietic stem cell blood bag cryo-cassette comprising: The utility model provides a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4).

2. The hematopoietic stem cell blood bag cryo-cassette of claim 1, wherein, The utility model discloses a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4).

3. The hematopoietic stem cell blood bag cryo-cassette of claim 2, wherein, The utility model discloses a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4).

4. The hematopoietic stem cell blood bag cryocontainer of claim 1, wherein, The utility model discloses a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4).

5. The hematopoietic stem cell blood bag cryo-cassette of claim 2, wherein, The utility model discloses a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4).

6. The hematopoietic stem cell blood bag cryocontainer of claim 1, wherein, The utility model discloses a protection box (1), it is characterized in that, the protection box (1) top is equipped with box cover (101), the protection box (1) inside is equipped with freezing cavity (2) and placement cavity (3), is equipped with baffle (102) between freezing cavity (2) and placement cavity (3), baffle (102) surface is equipped with through hole (103), placement cavity (3) side wall is fixedly connected with plate groove (401), and plate groove (401) inside is inserted with fixed plate (4). The utility model

Citation Information

Patent Citations

  • Liquid nitrogen storage hematopoietic stem cell blood bag cryopreservation box

    CN210338964U