Heat stroke small animal model training device
By designing a training device for a small animal model of heatstroke with adjustable tilt angle, breathable structure and video monitoring, the problems of high environmental requirements, poor comfort and easy damage to the control system of existing devices have been solved, and the accuracy of multi-scenario simulation and experimental results has been achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-21
- Publication Date
- 2026-03-27
AI Technical Summary
Existing training devices for small animal models of heatstroke have problems such as high requirements for laboratory environment, poor comfort of experimental personnel, susceptibility of control system to high temperature and humidity, inability to simulate various running training scenarios, and lack of video monitoring.
A training device for a small animal model of heatstroke was designed, comprising a treadmill, an inclination angle adjustment mechanism, a transparent enclosure structure, an electrical stimulation module, an image acquisition module, and a control module. The device features inclination angle adjustment, a breathable structure, video monitoring, and environmental control functions. The control module is placed outside the device to avoid the effects of high temperature and humidity.
It simulates various running training scenarios, ensuring the accuracy and progress of experimental results, preventing accidents, improving the comfort of experimental personnel, and extending the life of the device.
Smart Images
Figure CN224038174U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to animal experiment equipment technical field especially, relates to a heat stroke small animal model training device. BACKGROUND
[0002] At present, the heat stroke small animal model training mainly has the following schemes:
[0003] One is that the small animal model training is carried out in the laboratory of high temperature and high humidity;
[0004] Two is that the high temperature and high humidity gas is passed into the sealed labor training device to carry out the small animal model training;
[0005] Three is that the labor training device (small animal treadmill etc.) is directly placed in the high temperature and high humidity box to carry out the small animal model training by using the box to temporarily build the high temperature and high humidity simulation environment.
[0006] The first scheme not only requires the laboratory environment to be very high, but also the experimental site is relatively fixed, and the experimental personnel also need to enter the high temperature and high humidity environment to operate, which is very inconvenient, and the comfort of the experimental personnel is poor.
[0007] In the second scheme, since the sealed labor training device is directly provided with a sealed space outside the runway, the high temperature and high humidity space formed after the high temperature and high humidity gas is passed in is too small, and the internal air cannot be effectively circulated.
[0008] The third scheme is simple to operate, but according to the actual use, it is found that since the labor training device is directly placed in the high temperature and high humidity box, with the increase of the test times, the control system of the labor training device frequently fails or does not work, the main reason is that the circuit board and part of the components of the control system are oxidized and corroded due to long time work in the high temperature and high humidity environment, so the service life is shortened, which affects the function of the labor training device, not only affects the accuracy of the experimental results, but also affects the experimental progress.
[0009] The above three schemes do not have the video monitoring function, especially the third scheme, which is not conducive to observing the training state of the small animal model, cannot prevent the death of the small animal and other accidents, and cannot analyze the animal movement behavior characteristics in the later stage; at the same time, the runway of the existing labor training device is mostly horizontally arranged, does not have the inclination angle (slope) adjusting function, and cannot simulate multiple running training scenes. UTILITY MODEL CONTENT
[0010] In order to solve the defects of the prior art, the utility model provides a heat stroke small animal model training device.
[0011] The utility model discloses a technical scheme as follows:
[0012] A heat stroke small animal model training device, including labor training unit, the labor training unit includes treadmill and inclination angle adjusting mechanism;
[0013] The periphery of the treadmill is provided with a transparent enclosure for preventing small animals from escaping, an electric stimulation module is arranged inside the enclosure, and the electric stimulation module is located at the terminal end of the treadmill, the electric stimulation module stimulates the small animals staying at the terminal end of the treadmill to run by means of electric shock;
[0014] The inclination angle adjusting mechanism is used for adjusting the inclination angle of the treadmill, the inclination angle adjusting mechanism includes a base, two support plates are arranged at one end of the base, the frame at the terminal end of the treadmill is rotatably connected with the two support plates, a lifting mechanism is arranged at the other end of the base, the frame at the starting end of the treadmill is rotatably connected with the lifting mechanism, and the lifting mechanism is used for driving the starting end of the treadmill to rise and fall.
[0015] As a preferred embodiment of the utility model, the top of the enclosure is provided with an operation port, the operation port is used for taking and placing small animal models, and a cover plate for plugging the operation port is placed at the operation port;The enclosure and / or the enclosure and the treadmill have a ventilation structure, and the ventilation structure is an opening or a gap joint.
[0016] As a preferred embodiment of the utility model, the frame of the enclosure and the treadmill is detachably connected, and the electric stimulation module is detachably connected with the enclosure.
[0017] As a preferred embodiment of the utility model, the lifting mechanism includes a stepping motor, a universal coupling, a lead screw, a lead screw nut and two support arms, the stepping motor is arranged on the base between the two support plates, the output shaft of the stepping motor is connected with one end of the lead screw through the universal coupling, the lead screw nut is threadedly connected with the lead screw, and the two support arms are rotatably connected with the lead screw nut at the end close to each other, and the two support arms are rotatably connected with the frame at the starting end of the treadmill and the base at the end away from each other.
[0018] As a preferred embodiment of the utility model, it further includes a shelter, and the labor training unit is arranged inside the shelter.
[0019] An image acquisition module, an illumination module, a plurality of heating modules and a plurality of temperature and humidity sensors are arranged inside the shelter, the image acquisition module is used for acquiring video images at the labor training unit, the illumination module is used for providing illumination inside the shelter, the heating modules are used for heating air inside the shelter, and the temperature and humidity sensors are used for acquiring temperature and humidity values of the air inside the shelter.
[0020] The control module and the humidifying module are arranged outside the shelter, the humidifying module delivers moisture to the inside of the shelter through a pipeline, the image acquisition module and the plurality of groups of temperature and humidity sensors are in communication connection with the control module, and the control module is used for controlling the treadmill, the inclination angle adjusting mechanism, the electric stimulation module, the lighting module, the humidifying module and the plurality of heating modules to work.
[0021] As a preferred embodiment of the utility model, the heating module is composed of a PTC ceramic and a 24V fan; and the humidifying module is an ultrasonic atomization humidifier.
[0022] As a preferred embodiment of the utility model, the electric stimulation module comprises a constant current power supply and a stimulation electrode, the constant current power supply is arranged outside the shelter, the stimulation electrode is arranged inside the enclosure structure at the termination end of the treadmill inside the shelter, and the stimulation electrode is electrically connected with the constant current power supply through a wire.
[0023] As a preferred embodiment of the utility model, the utility model further comprises a man-machine interactive operation panel, and the man-machine interactive operation panel is in communication connection with the control module.
[0024] As a preferred embodiment of the utility model, the sidewall of the shelter is provided with a plurality of air exchange channels.
[0025] As a preferred embodiment of the utility model, the front side of the shelter is provided with a hatch, and the hatch is composed of a transparent material.
[0026] The utility model has the advantages of:
[0027] (1) The inclination angle (slope) of the treadmill is adjusted, so that the small animal model training track has the inclination angle (slope) adjustment function, thereby meeting the simulation requirements of various running training scenes;
[0028] (2) The small animal model labor running track (labor training unit) is built in the shelter, the control module, the man-machine interactive operation panel and the related auxiliary circuit which have requirements on the running environment (temperature, humidity, etc.) are placed outside the shelter, so as to avoid the influence of the high temperature and high humidity environment inside the shelter, ensure the smooth progress of the experiment and the accuracy of the experimental results, and prolong the service life of the device;
[0029] (3) The training state of the small animal model can be observed in real time through the monitoring video, and the recording monitoring video can be used for analyzing the ethological characteristics of the small animal model in the later stage;
[0030] (4) The hot flash disease small animal model is conveniently trained, the comfort of the experimental personnel is improved, the manufacturing cost is low, and the utility model is suitable for popularization and application in medical laboratories. BRIEF DESCRIPTION OF DRAWINGS
[0031] Figure 1 is the labor training unit structure schematic diagram of the utility model Figure 1 , wherein the treadmill is in a horizontal state;
[0032] Figure 2 is the labor training unit structure schematic diagram of the utility model Figure 2 , wherein the treadmill is in an inclined state;
[0033] Figure 3 is the labor training unit overhead schematic diagram of the utility model, wherein the cover plate is not shown;
[0034] Figure 4 is the square cabin structure schematic diagram of the utility model;
[0035] Figure 5 is the square cabin front view schematic diagram of the utility model, wherein the square cabin front side part shell and the cabin door are not shown;
[0036] Figure 6 is the circuit connection frame diagram of the utility model.
[0037] The meaning of the reference signs in the figure:
[0038] 1-treadmill, 2-enclosure structure, 3-electric stimulation module, 4-base, 5-supporting plate;
[0039] 6-cover plate, 7-opening, 8-gap joint, 9-connector, 10-screw;
[0040] 11-stepping motor, 12-universal coupling, 13-screw rod, 14-screw nut, 15-supporting arm;
[0041] 20-human-computer interaction operation panel, 21-square cabin, 22-ventilation channel, 23-cabin door;
[0042] 24-image acquisition module, 25-illumination module; 26-heating module, 27-temperature and humidity sensor;
[0043] 28-humidification module, 29-pipe;
[0044] 31-stimulation electrode, 41-control cabinet, 51-monitoring display. DETAILED DESCRIPTION
[0045] The utility model is specifically introduced below in combination with the drawings and specific embodiments.
[0046] For example, Figures 1-3As shown, the embodiment is a heatstroke small animal model training device, which comprises a labor training unit, the labor training unit comprises a treadmill 1 and an inclination angle adjusting mechanism; the periphery of the treadmill 1 is provided with a transparent enclosure structure 2 for preventing small animals from escaping, the enclosure structure 2 of the embodiment is made of transparent plastic, an electric stimulation module 3 is arranged inside the enclosure structure 2, and the electric stimulation module 3 is located at the terminal end of the treadmill 1, the electric stimulation module 3 stimulates small animals to run by means of electric shock when the small animals stay at the terminal end of the treadmill 1; the inclination angle adjusting mechanism can adjust the inclination angle of the treadmill 1, the inclination angle adjusting mechanism comprises a base 4, two support plates 5 are arranged at one end of the base 4, the terminal end of the treadmill 1 is located between the two support plates 5, and the frames on both sides of the terminal end of the treadmill 1 are rotationally connected with the two support plates 5 respectively; a lifting mechanism is arranged at the other end of the base 4, the frame at the starting end of the treadmill 1 is rotationally connected with the lifting mechanism, and the lifting mechanism can drive the frame at the starting end of the treadmill 1 to rise and fall, so as to realize the inclination angle (slope) adjustment of the treadmill 1, so that the small animal model training track has the inclination angle (slope) adjustment function and meets the simulation needs of various running training scenes.
[0047] As shown, Figures 1-3 The embodiment has an operation port at the top of the enclosure structure 2, small animal models are put in and taken out through the operation port, a cover plate 6 for plugging the operation port is arranged at the operation port, when in use, the cover plate 6 is taken up to open the operation port, and the cover plate 6 is placed to plug the operation port; a ventilation structure is arranged on the enclosure structure 2, the ventilation structure on the enclosure structure 2 is an array of holes 7; there is a gap 8 between the enclosure structure 2 and the treadmill 1, and the gap 8 constitutes the ventilation structure between the enclosure structure 2 and the treadmill 1; of course, in actual application, only the ventilation structure can be arranged on the enclosure structure 2, or only the ventilation structure can be arranged between the enclosure structure 2 and the treadmill 1; a connecting piece 9 is fixedly arranged on the frame of the treadmill 1, the enclosure structure 2 is connected with the connecting piece 9 through screws 10, so as to realize the detachable connection between the enclosure structure 2 and the frame of the treadmill 1; the electric stimulation module 3 is connected with the enclosure structure 2 through the screws 10 to realize the detachable connection.
[0048] The lifting mechanism in the embodiment comprises a stepping motor 11, a universal coupling 12, a lead screw 13, a lead screw nut 14 and two support arms 15, the stepping motor 11 is arranged on the base 4 between the two support plates 5, the output shaft of the stepping motor 11 is connected with one end of the lead screw 13 through the universal coupling 12, the lead screw nut 14 is threadedly connected with the lead screw 13, the two support arms 15 are rotationally connected with the lead screw nut 14 at the ends close to each other, and the two support arms 15 are rotationally connected with the frame at the starting end of the treadmill 1 and the base 4 at the ends away from each other; when the stepping motor 11 drives the lead screw 13 to rotate, the lead screw nut 14 moves linearly along the lead screw 13, and the lead screw nut 14 drives the two support arms 15 to make a scissors-like action, asFigure 1 and 2 As shown, when the two support arms 15 open, they support the starting end of the treadmill 1 to rise; when the two support arms 15 engage, they pull the starting end of the treadmill 1 to fall.
[0049] like Figures 4-6 As shown, this embodiment also includes a container 21, inside which the labor training unit is located. The side walls of the container 21 are provided with ventilation channels 22 equipped with filters; of course, the number of ventilation channels 22 can be appropriately increased. An openable hatch 23 is provided on the front side of the container 21. The hatch 23 is made of transparent material to facilitate real-time observation of the animal's movement and prevent accidents. Inside the container 21 are an image acquisition module 24, a lighting module 25, a heating module 26, and four sets of temperature and humidity sensors 27. The image acquisition module 24 is used to collect data from the labor training unit. The video images at the location of the animal model are captured by a camera in the image acquisition module 24. During training, the camera records the movement of the animal model and saves the images for later observation and analysis of its behavioral characteristics. A monitoring display 51 is installed outside the cabin 21, and the video images captured by the camera are displayed on the monitor 51. The lighting module 25 provides illumination for the interior of the cabin 21 and uses LED lights. The heating module 26 heats the air inside the cabin 21. The heating module 26 is composed of PTC ceramic and a 24V fan. The heat generated by the PTC ceramic is dissipated by the 24V fan, thus circulating and heating the air inside the cabin 21. In practical applications, multiple heating modules 26 can be set to improve the heating speed. The temperature and humidity sensors 27 collect the temperature and humidity values of the air inside the cabin 21. To ensure the accuracy of the measurement results, four sets of temperature and humidity sensors 27 are set, located on the sides, rear, and top center of the cabin 21. By measuring the temperature and humidity values at multiple points, the overall temperature and humidity of the cabin 21 can be evaluated. In practical applications... The number of temperature and humidity sensors 27 can be increased or decreased according to actual needs. A control module and a humidification module 28 are set outside the cabin 21. The humidification module 28 adopts an ultrasonic atomizing humidifier and delivers moisture into the cabin 21 through pipes 29, thereby humidifying the air inside the cabin 21. The image acquisition module 24 and four sets of temperature and humidity sensors 27 are connected to the control module. The control module can control the treadmill 1, the tilt angle adjustment mechanism, the electrical stimulation module 3, the lighting module 25, the humidification module 28, and the heating module 26.
[0050] In this embodiment, the electrical stimulation module 3 includes a constant current power supply and a stimulation electrode 31. The constant current power supply is located outside the cabin 21, and the stimulation electrode 31 is located inside the enclosure structure 2 at the end of the treadmill 1 inside the cabin 21. The stimulation electrode 31 is electrically connected to the constant current power supply through a wire (not shown in the figure).
[0051] As Figures 4-6 shown, the embodiment also includes a human-computer interaction operation panel 20, which is in communication connection with the control module; the human-computer interaction operation panel 20 adopts a touch display screen, which can display the temperature value, humidity value and related information such as the speed of the treadmill 1, the stimulating current of the electric stimulation module 3, etc. in the shelter 21, at the same time, the operator inputs the control instruction to the control module through the touch display screen, and the control module controls the driving motor of the treadmill 1, the stepping motor 11 of the inclination angle adjusting mechanism, the constant current power supply of the electric stimulation module 3, the LED lamp of the lighting module 25, the humidifying module 28 and the heating module 26 to work according to the control instruction, so as to realize the speed control of the treadmill 1, the inclination angle control of the treadmill 1, the stimulating current control of the electric stimulation module 3, the light control of the shelter 21, the humidity control of the shelter 21 and the temperature control of the shelter 21; the control module adopts a microcontroller with Arduino as the core; a control cabinet 41 is arranged on the top outer side of the shelter 21, the control module and the constant current power supply are arranged in the control cabinet 41, the human-computer interaction operation panel 20 and the monitoring display 51 are arranged on the front side of the control cabinet 41, and various cables in the shelter 21 pass through the top shell of the shelter 21 and then enter the control cabinet 41, and the various cables and the top shell of the shelter 21 are sealed, so that the control cabinet 41 and the shelter 21 are not connected.
[0052] When the small animal model is trained, first, the lighting module 25 is started to illuminate the inside of the shelter 21, then the inclination angle of the treadmill 1 is adjusted through the inclination angle adjusting mechanism, then the small animal model (usually a mouse) is put on the track of the treadmill 1 in the enclosure structure 2 through the opening of the door 23, and the door 23 is closed; the humidifying module 28 is started to work, the heating module 26 is started to work, the inside of the shelter 21 gradually forms a high-temperature and high-humidity environment, the inside of the enclosure structure 2 is communicated with the inside of the shelter 21 through the air permeable structure, the high-temperature and high-humidity air enters the inside of the enclosure structure 2 through the air permeable structure and flows out from the inside of the enclosure structure 2; the treadmill 1 is started, the small animal model starts to run on the track of the treadmill 1, the electric stimulation module 3 is started to stimulate the small animal model to run through the electric shock, the image acquisition module 24 acquires the video image in the inside of the shelter 21 to record the motion picture of the small animal model, and the temperature and humidity sensor 27 acquires the temperature value and humidity value of the air in the inside of the shelter 21 in real time.
[0053] The utility model has the following advantages:
[0054] The first advantage is that the inclination angle (slope) of the treadmill is adjusted, the small animal model training track has the inclination angle (slope) adjusting function, and the simulation demand of various running training scenes is met;
[0055] The second advantage is that the small animal model labor running track (labor training unit) is arranged in the shelter, the control module with requirements for the running environment (temperature, humidity, etc.), the man-machine interaction operation panel and the related auxiliary circuit are arranged outside the shelter, the high temperature and high humidity environment inside the shelter is avoided, the experiment progress is ensured to be carried out smoothly, the accuracy of the experimental results is ensured, and the service life of the device is prolonged;
[0056] The third advantage is that the training state of the small animal model can be observed in real time through the monitoring video, the occurrence of unexpected situations is prevented, and the monitoring video recorded can be used for analyzing the behavioral characteristics of the small animal model in the later period.
[0057] The fourth advantage is that the operation is simple and convenient, the heatstroke small animal model is conveniently trained, the comfort of the experimental personnel is improved, the manufacturing cost is low, and the device is suitable for popularization and application in a medical laboratory.
[0058] In the description of the utility model, it is understood that: the orientation or position relationship indicated by the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like are all based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the utility model, and are not indicative or suggestive of the device or element being indicated must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the utility model.
[0059] In the description of the utility model, it should be explained that: unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "setting", "forming" should be understood broadly; for example: it can be fixedly connected, set, or can be detachably connected, set, or can be an integral structure; it can be mechanically connected, or electrically connected; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the communication between two elements; for those skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific situation.
[0060] The above embodiments are only used to illustrate the technical scheme of the utility model, and those skilled in the art should understand that the above embodiments do not limit the utility model in any form, and any technical scheme obtained by equivalent replacement or equivalent transformation falls within the protection scope of the utility model.
Claims
1. A training device for a small animal model of heatstroke, characterized in that: The labor training unit comprises a treadmill and a tilt angle adjusting mechanism; The treadmill is provided with a transparent enclosure for preventing small animals from escaping, and an electric stimulation module is arranged inside the enclosure and at the end of the treadmill, which stimulates the small animals to run by electric shock when they stay at the end of the treadmill. The tilt angle adjusting mechanism is used for adjusting the tilt angle of the treadmill, and comprises a base, two support plates arranged at one end of the base, a frame at the end of the treadmill rotatably connected with the two support plates, a lifting mechanism arranged at the other end of the base, and a frame at the start end of the treadmill rotatably connected with the lifting mechanism.
2. The heat stroke small animal model training device according to claim 1, wherein, The top of the enclosure is provided with an operation port for taking and placing a small animal model, and a cover plate is arranged at the operation port to block the operation port.
3. The heat stroke model training device for small animals according to claim 1, wherein The enclosure and / or the enclosure and the treadmill are provided with a ventilation structure, which is an opening or a gap.
4. The heat stroke model training device for small animals according to claim 1, wherein The enclosure and the treadmill are detachably connected, and the electric stimulation module and the enclosure are detachably connected.
5. The heat stroke small animal model training device according to any one of claims 1-4, characterized in that, The lifting mechanism comprises a stepping motor, a universal coupling, a lead screw, a lead screw nut, and two support arms, the stepping motor is arranged on the base between the two support plates, the output shaft of the stepping motor is connected with one end of the lead screw through the universal coupling, the lead screw nut is threadedly connected with the lead screw, and the two support arms are rotatably connected with the lead screw nut at one end close to each other and rotatably connected with the frame at the start end of the treadmill and the base at the other end away from each other. The labor training unit is arranged inside the shelter. An image acquisition module, a lighting module, a plurality of heating modules, and a plurality of temperature and humidity sensors are arranged inside the shelter, the image acquisition module is used to acquire video images of the labor training unit, the lighting module is used to provide lighting inside the shelter, the heating modules are used to heat the air inside the shelter, and the temperature and humidity sensors are used to acquire temperature and humidity values of the air inside the shelter.
6. The heat stroke small animal model training device according to claim 5, characterized in that, A control module and a humidifying module are arranged outside the shelter, the humidifying module sends humid air to the inside of the shelter through a pipeline, the image acquisition module and the plurality of temperature and humidity sensors are in communication connection with the control module, and the control module is used to control the operation of the treadmill, the tilt angle adjusting mechanism, the electric stimulation module, the lighting module, the humidifying module, and the plurality of heating modules.
7. The heat stroke model training device for small animals according to claim 5, wherein The heating module is composed of a PTC ceramic and a 24V fan, and the humidifying module is an ultrasonic atomizing humidifier.
8. The heat stroke model training device for small animals according to claim 5, wherein The electric stimulation module comprises a constant current power supply and a stimulation electrode, the constant current power supply is arranged outside the shelter, and the stimulation electrode is arranged inside the enclosure at the end of the treadmill inside the shelter, and the stimulation electrode is electrically connected with the constant current power supply through a wire.
9. The heat stroke model training device for small animals according to claim 5, wherein A human-computer interaction operation panel is further included, which is in communication connection with the control module.
10. The heat stroke model training device for small animals according to claim 5, wherein The sidewall of the shelter is provided with a plurality of ventilation channels. The front side of the shelter is provided with a hatch, which is made of transparent material.