Sterilization device for nucleic acid medicine processing

Abstract

The utility model provides a sterilization device for nucleic acid medicine processing, and belongs to the technical field of medical equipment, the sterilization device comprises an isolation box and a liquid storage box on one side of the isolation box, a disinfection water tank is arranged in the middle of the interior of the isolation box, driving mechanisms used for driving the disinfection water tank to move in the vertical direction are arranged on the two sides of the disinfection water tank, and a flow guide plate is arranged on the upper portion of the interior of the isolation box. According to the scheme, the back-up roll is arranged, the back-up roll swings under the action of buoyancy when the back-up roll is immersed by the disinfectant accumulated in the disinfection water tank, so that the effect of adjusting the position of the raw material is achieved, and the contact part of the corresponding back-up roll and the raw material is also adjusted; therefore, the disinfectant can uniformly cover the surface of the raw material, and the existence of dead angles is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, in particular to a sterilization device for nucleic acid drug processing. BACKGROUND

[0002] Nucleic acid drugs refer to drugs based on nucleic acids. Such drugs mainly regulate gene expression or function by interacting with nucleic acids in cells, thereby achieving therapeutic effects, and show great application potential in the fields of gene therapy, cancer immunotherapy, treatment of genetic diseases, etc. In order to ensure the safety and effectiveness of the drugs, sterilization treatment is needed in the manufacturing process of nucleic acid drugs to overcome the adverse effects of microorganisms on the drugs.

[0003] The prior art disclosed in Patent No. CN220090024U discloses a gel raw material sterilization device, which can disinfect raw materials by being provided with a spray head, a connecting pipe, a hose, a water pump, a UV sterilization lamp, a clamping groove and a clamping block.

[0004] The above sterilization device has a disinfection dead angle at the contact position of the raw material and the supporting slide roller in actual use, and the disinfectant and the UV cannot act on the dead angle position, which affects its effectiveness.

[0005] Therefore, the present application provides a sterilization device for nucleic acid drug processing to meet the needs. CONTENT OF THE INVENTION

[0006] Therefore, the present application provides a sterilization device for nucleic acid drug processing to meet the needs.

[0007] To solve the above technical problems, the present application provides the following technical solutions:

[0008] A sterilization device for nucleic acid drug processing, comprising an isolation box and a liquid storage tank on one side of the isolation box, a disinfectant tank is arranged in the middle of the interior of the isolation box, drive mechanisms for driving the disinfectant tank to move in the vertical direction are arranged on both sides of the disinfectant tank, a flow guide plate is arranged above the interior of the isolation box, a sleeve is arranged at the bottom of the isolation box, the sleeve is connected in communication with the liquid storage tank through a corrugated pipe, a piston is arranged in the interior of the sleeve, the other end of the piston is connected to the bottom of the disinfectant tank, a connecting pipe is connected to the top of the liquid storage tank, a spray head is connected to one end of the connecting pipe penetrating through the isolation box, a spring one is connected to the bottom of the disinfectant tank, a slide block is arranged at the top of the spring one, and a hollow supporting roller is eccentrically arranged between the two slide blocks.

[0009] Preferably, the flow guide plate is of a conical structure, and the bottom opening of the flow guide plate is square.

[0010] Preferably, the top of the sliding block is provided with a protrusion, which is arranged directly below the deflector.

[0011] Preferably, a plurality of support rollers are arranged in parallel and spaced apart between the two sliding blocks.

[0012] Preferably, the bottom of the disinfecting sink is provided with a wedge-shaped rubber plug, the bottom of the banana is connected with a support rod, the middle of the support rod is provided with a baffle, and a spring two is arranged between the baffle and the rubber plug.

[0013] Preferably, the bottom of the disinfecting sink is provided with a wedge-shaped rubber plug, the bottom of the banana is connected with a support rod, the middle of the support rod is provided with a baffle, and a spring two is arranged between the baffle and the rubber plug.

[0014] Preferably, the driving mechanism comprises a servo motor and a lead screw, the lead screw penetrates the side wall of the disinfecting sink, and the servo motor and the lead screw are in transmission relationship.

[0015] Compared with the prior art, the present application has at least the following beneficial effects:

[0016] In the above scheme, by arranging the support rollers, as the disinfecting liquid accumulated in the disinfecting sink submerges the support rollers, the support rollers swing due to the action of the buoyancy, thereby achieving the effect of adjusting the position of the raw materials. Correspondingly, the contact part of the support rollers and the raw materials is also adjusted, so that the disinfecting liquid can uniformly cover the surface of the raw materials, reducing the existence of dead angles.

[0017] In the above scheme, by arranging the sliding block, spring one, protrusion and deflector, the support rollers can be moved downward to the position below the disinfecting sink by moving the sliding block downward relative to the disinfecting sink, so that the raw materials supported by the support rollers can be submerged in the disinfecting liquid in the disinfecting sink, thereby making the disinfecting liquid completely cover the raw materials, achieving good disinfection and sterilization effect. BRIEF DESCRIPTION OF DRAWINGS

[0018] The accompanying drawings, which are incorporated herein and constitute part of the specification, illustrate embodiments of the present disclosure and, together with the description, further serve to explain the principles of the present disclosure and to enable a person skilled in the relevant art to implement and use the present disclosure.

[0019] Figure 1 It is a schematic diagram of the overall structure in the present application;

[0020] Figure 2 It is a schematic diagram of the support roller structure in the present application;

[0021] Figure 3 It is a schematic diagram of the disinfecting sink structure in the present application;

[0022] Figure 4 It is a schematic diagram of the connecting pipe structure in the application;

[0023] Figure 5 It is a schematic diagram of the sleeve cross-section structure in the application;

[0024] Figure 6 It is a schematic diagram of the rubber plug structure in the application.

[0025] [Reference signs]

[0026] The isolation box 1, the flow guide plate 101, the sleeve 102, the one-way valve one 1021, the corrugated pipe 103, the one-way valve two 1031, the piston 104, the liquid storage tank 2, the connecting pipe 201, the spray head 202, the disinfectant tank 3, the spring one 301, the sliding block 302, the protruding block 3021, the supporting roller 303, the rubber plug 304, the supporting rod 3041, the baffle 3042, the spring two 3043, the servo motor 4, the lead screw 401. DETAILED DESCRIPTION

[0027] As shown in Figure 1 , Figure 2 , Figure 3 and Figure 4 A sterilization device for processing nucleic acid drugs is provided. The embodiment of the application provides a device, which comprises an isolation box 1 and a liquid storage tank 2 on one side of the isolation box 1. A disinfectant tank 3 is arranged in the middle of the inside of the isolation box 1. Drive mechanisms for driving the disinfectant tank 3 to move in the vertical direction are arranged on both sides of the disinfectant tank 3. A flow guide plate 101 is arranged above the inside of the isolation box 1. A sleeve 102 is arranged at the bottom of the isolation box 1. The sleeve 102 is connected to the liquid storage tank 2 in a communication mode through a corrugated pipe 103. A piston 104 is arranged in the inside of the sleeve 102. The other end of the piston 104 is connected to the bottom of the disinfectant tank 3. A connecting pipe 201 is connected to the top of the liquid storage tank 2. The connecting pipe 201 penetrates the isolation box 1 and is connected to a spray head 202 at one end. A spring one 301 is connected to the bottom of the disinfectant tank 3. Sliding blocks 302 are arranged at the top of the spring one 301. A hollow supporting roller 303 is arranged between the two sliding blocks 302 in an eccentric mode.

[0028] A box door is hingedly connected to the opening part of the isolation box 1. The relative closed state of the isolation box 1 can be realized by closing the box door, thereby improving safety.

[0029] In actual use, the nucleic acid drug raw material to be sterilized is placed on the supporting roller 303, the disinfecting water tank 3 is driven by the driving mechanism to move upward in the vertical direction, the disinfecting water tank 3 drives the piston 104 to move upward, the piston 104 extrudes the air in the sleeve 102 into the bellows 103, the other end of the bellows 103 is connected with the liquid storage tank 2, as the pressure in the liquid storage tank 2 increases, the disinfectant pre-injected in the liquid storage tank 2 is transported to the spray head 202 through the communication pipe 201, and the disinfectant is sprayed in the form of fine mist from the spray head 202 under the action of pressure, and the outer surface of the raw material is subjected to sterilization treatment by the disinfectant;

[0030] The disinfectant settled on the flow guide plate 101 can be concentrated and guided to the disinfecting water tank 3, and the disinfecting water tank 3 also has a collecting effect on the disinfectant dropping on the surface of the raw material. As the disinfectant accumulated in the disinfecting water tank 3 increases, the disinfectant submerges the supporting roller 303, and the supporting roller 303 swings due to the action of buoyancy, thereby achieving the effect of adjusting the position of the raw material. Correspondingly, the contact part of the supporting roller 303 with the raw material is also adjusted, so that the disinfectant can uniformly cover the surface of the raw material, and the existence of dead angles is reduced.

[0031] In this embodiment, as shown in Figures 2-6 The bottom opening of the flow guide plate 101 is square.

[0032] The distribution of the droplets sprayed by the spray head 202 presents a form of more in the middle and gradually decreasing on both sides. The flow guide plate 101 can well guide the disinfectant to flow to the disinfecting water tank 3, thereby reducing the waste of disinfectant.

[0033] The top of the sliding block 302 is provided with a protrusion 3021, which is arranged directly below the flow guide plate 101.

[0034] As the disinfecting water tank 3 is driven by the driving mechanism to move upward in the vertical direction, the protrusion 3021 arranged on the sliding block 302 is limited by the flow guide plate 101, so that the spring 301 is compressed, and the sliding block 302 moves downward relative to the disinfecting water tank 3, so that the supporting roller 303 can move downward to a position below the disinfecting water tank 3, so that the supporting roller 303 and the raw material supported thereby can be immersed in the disinfectant in the disinfecting water tank 3, thereby making the disinfectant completely cover the raw material, and achieving a good disinfection and sterilization effect.

[0035] A plurality of supporting rollers 303 arranged in parallel and at intervals are arranged between the two sliding blocks 302.

[0036] The number of support rollers 303 is determined according to the size of the raw material of the medicine, and the support roller 303 is rotatably connected with the sliding block 302. When the support roller 303 is eccentrically installed with the sliding block 302, the sterilizing liquid accumulated in the sterilizing tank 3 does not contact the support roller 303, and the support roller 303 is affected by gravity, and the axis is located below the hinged part. As the sterilizing liquid in the sterilizing tank 3 continues to increase, the buoyancy of the sterilizing liquid on the support roller 303 makes it swing, and the swing of the support roller 303 changes its own position, and the corresponding contact position of the support roller 303 with the raw material is also adjusted, so that the sterilizing liquid can cover the surface of the raw material, and a good sterilization and disinfection effect is achieved.

[0037] The bottom of the sterilizing tank 3 is provided with a wedge-shaped rubber plug 304, the bottom of the banana plug 304 is connected with a support rod 3041, the middle part of the support rod 3041 is provided with a baffle 3042, and the baffle 3042 is provided with a spring 3043 between the rubber plug 304;

[0038] When the sterilizing liquid accumulated in the sterilizing tank 3 needs to be discharged, the driving mechanism drives the sterilizing tank 3 to move downward, so that the support rod 3041 contacts the bottom side wall of the isolation box 1, and the sterilizing tank 3 continues to move downward, and the rubber plug 304 moves upward relative to the sterilizing tank 3, so that the sterilizing liquid in the sterilizing tank 3 can be discharged into a safe container, improving the safety.

[0039] The sleeve 102 is arranged at the bottom of the sterilizing tank 3, the top of the sleeve 102 is provided with a one-way valve 1021, and the corrugated pipe 103 is provided with a one-way valve 1031 matched therewith;

[0040] The sleeve 102 is shielded by the sterilizing tank 3, which can reduce the influence of the sterilizing liquid on the sleeve 102, the one-way valve 1021 is used to supplement air into the sleeve 102, and the one-way valve 1031 is used to prevent the sterilizing liquid in the liquid storage tank 2 from flowing back into the sleeve 102;

[0041] In actual use, the end of the corrugated pipe 103 penetrating the liquid storage tank 2 is arranged at the upper position inside the liquid storage tank 2, so as to reduce the contact of the corrugated pipe 103 with the sterilizing liquid and prevent the sterilizing liquid from entering the sleeve 102;

[0042] Meanwhile, the end of the connecting pipe 201 penetrating the liquid storage tank 2 is arranged at the lower position inside the liquid storage tank 2, so as to prevent the connecting pipe 201 from interfering with the corrugated pipe 103, and facilitate the discharge of the sterilizing liquid in the liquid storage tank 2.

[0043] The driving mechanism comprises a servo motor 4 and a lead screw 401, the lead screw 401 penetrates the side wall protrusion of the sterilizing tank 3, and the transmission relationship is established between the servo motor 4 and the lead screw 401;

[0044] The rotation of the screw rod 401 is driven by the servo motor 4, the screw rod 401 is connected with the side wall protrusion of the disinfecting water tank 3 through threads, the moving direction of the disinfecting water tank 3 can be controlled by adjusting the rotating direction of the servo motor 4, and the bottom side wall of the isolation box 1 is further provided with a guide rod, the guide rod penetrates through four end corner positions of the disinfecting water tank 3, and the guide rod provides a guiding action.

[0045] The servo motor 4 is provided with a matched power supply and a controller, so that intelligent control can be realized.

Claims

1. A sterilization device for nucleic acid drug processing, comprising an isolation tank (1) and a liquid storage tank (2) on one side of the isolation tank (1), characterized in that, The middle part of the inside of the isolation box (1) is provided with a disinfectant water tank (3), both sides of the disinfectant water tank (3) are provided with a driving mechanism for driving it to move in the vertical direction, the inside of the isolation box (1) is provided with a flow guide plate (101), the bottom of the isolation box (1) is provided with a sleeve (102), the sleeve (102) is connected with the liquid storage tank (2) through the corrugated pipe (103), the inside of the sleeve (102) is provided with a piston (104), the other end of the piston (104) is connected to the bottom of the disinfectant water tank (3), the top of the liquid storage tank (2) is connected with a connecting pipe (201), one end of the connecting pipe (201) penetrating the isolation box (1) is connected with a spray head (202), the bottom of the disinfectant water tank (3) is connected with a spring (301), the top of the spring (301) is provided with a sliding block (302), two sliding blocks (302) are provided with eccentrically installed hollow support rollers (303).

2. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: The flow guide plate (101) is a conical structure, and the bottom opening of the flow guide plate (101) is square.

3. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: The top of the sliding block (302) is provided with a protruding block (3021), and the protruding block (3021) is arranged directly below the flow guide plate (101).

4. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: A plurality of support rollers (303) are arranged in parallel between the two sliding blocks (302).

5. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: The bottom of the disinfectant water tank (3) is provided with a wedge-shaped rubber plug (304), the bottom of the rubber plug (304) is connected with a support rod (3041), the middle part of the support rod (3041) is provided with a baffle (3042), and the baffle (3042) and the rubber plug (304) are provided with a spring (3043).

6. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: The sleeve (102) is arranged at the bottom of the disinfectant water tank (3), and the top of the sleeve (102) is provided with a one-way valve (1021), and the corrugated pipe (103) is provided with a matching one-way valve (1031).

7. The germicidal device for processing a nucleic acid drug according to claim 1, characterized by: The driving mechanism comprises a servo motor (4) and a lead screw (401), the lead screw (401) protrudes through the side wall of the disinfectant water tank (3), and the servo motor (4) and the lead screw (401) are in transmission relationship.

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