Sampling device for medicine transdermal tester
By designing a detachable sampling device for the transdermal drug testing instrument, the problem of having to replace the entire unit when a component is damaged is solved, enabling flexible maintenance and stable installation, reducing maintenance costs, and improving ease of operation.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- TIANJIN JINCHUANGZHIKE TECHNOLOGY DEVELOPMENT CO LTD
- Filing Date
- 2025-05-12
- Publication Date
- 2026-04-21
AI Technical Summary
Existing transdermal drug testing devices require replacement of the entire device when a component is damaged, increasing maintenance costs. Furthermore, the operation is cumbersome and susceptible to human error.
Design a detachable sampling device that allows for the replacement of individual components via a locking plate and protective mechanism, avoiding integrated design. Employ a threaded connection and flip-to-unlock mechanism to simplify the maintenance process.
It reduces maintenance costs, improves the flexibility and ease of operation of the device, and ensures the stability and safety of the installation.
Smart Images

Figure CN224152109U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical equipment technology, and in particular to a sampling device for a transdermal drug testing instrument. Background Technology
[0002] In the process of drug development and quality control, accurately measuring the transdermal rate and penetration volume of drugs is crucial for evaluating drug efficacy, safety, and optimizing formulation. Drug transdermal testing instruments can simulate the penetration process of drugs on human skin, while the sampling device, as a key component, is responsible for accurately collecting transdermal receiving fluid samples at different time points, providing a reliable basis for subsequent drug concentration analysis.
[0003] Existing sampling devices require manual operation to complete the sampling and cleaning steps, which is not only cumbersome and time-consuming, but also prone to human error. The current solution is to introduce a microprocessor-based system with programmed controls to automate the sampling process. Operators only need to set the parameters of sampling time, volume, and number of samples on the human-machine interface, and the device can automatically complete the entire sampling process according to the preset program. However, the sampling device is still an integrated design, which means that if a component is damaged, the entire sampling device must be replaced instead of a single part, increasing maintenance costs. Utility Model Content
[0004] To overcome the above shortcomings, this utility model provides a sampling device for a transdermal drug testing instrument, which aims to improve the problem in the prior art that when a component is damaged, it is impossible to directly replace a single part, thus increasing maintenance costs.
[0005] To achieve the above objectives, the present invention adopts the following technical solution: a sampling device for a transdermal drug testing instrument, comprising a sampling shell, a locking plate rotatably connected to both the upper and lower sides of the sampling shell, a fixing block fixedly connected to each adjacent side of the two locking plates, a connecting shell threadedly connected to the front end of the inner wall of the sampling shell, a threaded groove formed on the rear side of the outer wall of the connecting shell, a locking groove formed on both the upper and lower sides of the connecting shell, each of the two fixing blocks engaging with the corresponding locking groove on its adjacent side, a conveying shell connected to the front end of the connecting shell, a sampling head connected to the front end of the conveying shell, a sealing shell fixedly connected to the middle of each adjacent side of the two locking plates, each of the two sealing shells engaging with the outer wall of the connecting shell on its adjacent side, and a protective mechanism provided at the rear end of the outer wall of the sampling shell for protecting the installation and connection position of the sampling device.
[0006] As a further description of the above technical solution:
[0007] The protective mechanism includes a fixing plate, the inner wall of which is fixedly connected to the rear end of the outer wall of the sampling shell. The left and right sides of the fixing plate are rotatably connected to a rotating shaft. The outer wall of the rotating shaft is rotatably connected to two protective shells. The top left and right sides of the bottom protective shell are threadedly connected to threaded rods. The bottom end of the threaded rod is fixedly connected to a knob. The top end of the threaded rod is threadedly connected to the bottom of the top protective shell.
[0008] As a further description of the above technical solution:
[0009] The protective mechanism also includes two rubber pads, with the opposite sides of the two rubber pads fixedly connected to adjacent sides of the inner walls of the two protective shells.
[0010] As a further description of the above technical solution:
[0011] The top protective shell has positioning posts fixedly connected to the left and right sides of its bottom wall, and the bottom protective shell has positioning grooves on the left and right sides of its top rear side, with the bottom ends of the positioning posts engaging with the positioning grooves.
[0012] As a further description of the above technical solution:
[0013] The outer walls of both knobs are fixedly connected with multiple protrusions, and the multiple protrusions are connected in an equidistant ring.
[0014] As a further description of the above technical solution:
[0015] The outer wall of the sampling shell is fixedly connected with multiple protective rings, and the multiple protective rings are connected at equal intervals.
[0016] As a further description of the above technical solution:
[0017] Multiple rubber blocks are fixedly connected to the opposite sides of the two locking plates, and the multiple rubber blocks are all rectangular in design.
[0018] As a further description of the above technical solution:
[0019] A scale is fixedly connected to the right side of the sampling shell, and the outer wall of the scale is designed to be smooth.
[0020] This utility model has the following beneficial effects:
[0021] 1. In this utility model, by flipping the locking plate, it is unlocked from one side of the connecting shell. At the same time, the two sealing rings are flipped open synchronously, thereby rotating the connecting shell so that it can be rotated through the threaded groove and removed, achieving the effect of disassembly and separation. This avoids the situation where the sampling head is damaged and the whole structure needs to be replaced due to the integrated design, thereby reducing maintenance costs and increasing the flexibility of the device.
[0022] 2. In this utility model, the sampling shell is installed and connected to the testing equipment at its rear end. Then, by flipping the protective shell, the two protective shells can lock and protect the installation position of the device. Then, by rotating the knob, the top end can rotate upward, thereby achieving the purpose of locking the bottom protective shell and the top protective shell, thus improving the strength of the installation position of the sampling device and the testing equipment. Attached Figure Description
[0023] Figure 1 This is a perspective view of a sampling device for a transdermal drug testing instrument proposed in this utility model;
[0024] Figure 2 This is a front view of a sampling device for a transdermal drug testing instrument proposed in this utility model;
[0025] Figure 3 This is a schematic diagram of the connecting shell of a sampling device for a transdermal drug testing instrument proposed in this utility model;
[0026] Figure 4 This is an exploded view of the locking plate of a sampling device for a transdermal drug testing instrument proposed in this utility model;
[0027] Figure 5 This is a schematic diagram of the protection mechanism of the sampling device for a transdermal drug testing instrument proposed in this utility model.
[0028] Legend:
[0029] 1. Sampling shell; 2. Protective mechanism; 201. Fixing plate; 202. Rotating shaft; 203. Protective shell; 204. Threaded rod; 205. Knob; 206. Rubber pad; 207. Positioning post; 208. Positioning groove; 209. Protrusion; 3. Locking plate; 4. Fixing block; 5. Connecting shell; 6. Threaded groove; 7. Locking groove; 8. Conveying shell; 9. Sealing shell; 10. Sampling head; 11. Protective ring; 12. Rubber block; 13. Scale. Detailed Implementation
[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0031] Reference Figure 1 , Figure 3 and Figure 4This utility model provides an embodiment of a sampling device for a transdermal drug testing instrument, comprising a sampling shell 1, with locking plates 3 rotatably connected to both the upper and lower sides of the sampling shell 1. The two locking plates 3 can connect and fix a connecting shell 5. A fixing block 4 is fixedly connected to each adjacent side of the two locking plates 3. A connecting shell 5 is threadedly connected to the front end of the inner wall of the sampling shell 1. A threaded groove 6 is provided on the rear side of the outer wall of the connecting shell 5, allowing the connecting shell 5 to be installed on the front end of the inner wall of the sampling shell 1. Locking grooves 7 are provided on both the upper and lower sides of the connecting shell 5, and two fixing blocks 4... The adjacent sides of the two locking plates 3 are respectively engaged with the corresponding locking grooves 7. The front end of the connecting shell 5 is connected to the conveying shell 8, and the front end of the conveying shell 8 is connected to the sampling head 10. Transdermal sampling can be performed through the sampling head 10. The middle of the adjacent sides of the two locking plates 3 is fixedly connected to the sealing shell 9. The adjacent sides of the two sealing shells 9 are engaged with the outer wall of the connecting shell 5. The connection of the sealing shells 9 can improve the sealing of the connection position between the connecting shell 5 and the sampling shell 1. The rear end of the outer wall of the sampling shell 1 is provided with a protection mechanism 2. The protection mechanism 2 is used to protect the installation and connection position of the sampling device.
[0032] Specifically, when disassembling and replacing the sampling head 10, the locking plate 3 is flipped to unlock it from the locking groove 7 on one side of the connecting shell 5. After initial unlocking, the two sealing shells 9 are flipped outwards simultaneously to release the sealing effect. Then, the connecting shell 5 is rotated to release the threaded connection between its rear end and the front side of the inner wall of the sampling shell 1 through the threaded groove 6, allowing the connecting shell 5 to be removed. This achieves the purpose of disassembling the connecting shell 5, the conveying shell 8, and the sampling head 10. When these components need to be reinstalled, the operation can be performed in reverse order. This avoids the inconvenience of replacing the entire structure when the sampling head 10 is damaged due to the integrated design, reduces maintenance costs, increases the flexibility of the device, and makes the maintenance of the device more convenient and faster.
[0033] Reference Figure 1 , Figure 2 and Figure 5 The protection mechanism 2 includes a fixing plate 201. The inner wall of the fixing plate 201 is fixedly connected to the rear end of the outer wall of the sampling shell 1. The fixing plate 201 can support the protective shell 203 to complete the rotational connection. The left and right sides of the fixing plate 201 are rotatably connected to the rotating shaft 202. The outer wall of the rotating shaft 202 is rotatably connected to two protective shells 203. The top left and right sides of the bottom protective shell 203 are threadedly connected to the threaded rod 204, so that the threaded rod 204 rotates upward under the rotation, thereby enabling the threaded connection to the top protective shell 203. The bottom end of the threaded rod 204 is fixedly connected to the knob 205. The top end of the threaded rod 204 is threadedly connected to the bottom of the top protective shell 203, thereby achieving the locking of the two protective shells 203 and completing the protection effect of the device installation position.
[0034] Specifically, after the sampling shell 1 is installed and connected to the testing equipment, the two protective shells 203 need to be flipped so that they can provide effective locking protection at the installation connection of the device. After flipping, the knob 205 is rotated so that the threaded rod 204 and the knob 205 rotate upward. When the top of the threaded rod 204 is connected to the threaded part of the top protective shell 203, the bottom protective shell 203 and the top protective shell 203 are locked together, thereby improving the protection effect at the installation connection of the sampling device and the testing equipment and ensuring the safety and stability of the device.
[0035] Reference Figure 2 and Figure 5 The protective mechanism 2 also includes two rubber pads 206, with the opposite sides of the two rubber pads 206 fixedly connected to adjacent sides of the inner walls of the two protective shells 203; positioning posts 207 are fixedly connected to the left and right sides of the bottom wall of the top protective shell 203, and positioning grooves 208 are opened at the left and right ends of the top rear side of the bottom protective shell 203, with the bottom ends of the positioning posts 207 engaging with the positioning grooves 208; multiple protrusions 209 are fixedly connected to the outer walls of the two knobs 205, and the multiple protrusions 209 are connected in an equidistant ring.
[0036] Specifically, the two rubber pads 206 can improve the fixing effect during device installation, the engagement of the positioning post 207 and the positioning groove 208 can improve the positioning effect when the two protective shells 203 are engaged, and the connection of multiple protrusions 209 can improve the protection effect on the outer wall of the knob 205.
[0037] Reference Figure 1 , Figure 2 and Figure 3 Multiple protective rings 11 are fixedly connected to the outer wall of the sampling shell 1, and the multiple protective rings 11 are all connected at equal intervals; multiple rubber blocks 12 are fixedly connected to the opposite side of the two locking plates 3, and the multiple rubber blocks 12 are all rectangular; a scale 13 is fixedly connected to the right side of the sampling shell 1, and the outer wall of the scale 13 is smooth.
[0038] Specifically, multiple protective rings 11 reduce external damage to the sampling shell 1, multiple rubber blocks 12 increase the static friction of the locking plate 3 during use, improving the anti-slip effect, and the scale 13 allows observation of the sampling volume.
[0039] Working principle: When disassembling and replacing the sampling head 10, the locking plate 3 is flipped to unlock it from the locking groove 7 on one side of the connecting shell 5. At the same time, the two sealing shells 9 are flipped outwards to open, achieving a preliminary unlocking effect. Then, by rotating the connecting shell 5, its rear end is threaded through the threaded groove 6 and connected to the front side of the inner wall of the sampling shell 1, thus achieving the purpose of disassembling the connecting shell 5, the conveying shell 8 and the sampling head 10. Conversely, the installation is completed. This avoids the situation where the sampling head 10 is damaged and the whole structure needs to be replaced due to the integrated design, thereby reducing maintenance costs, increasing the flexibility of the device and facilitating the maintenance operation of the device.
[0040] Furthermore, after the sampling shell 1 is installed and connected to the testing equipment, the two protective shells 203 are flipped to lock and protect the connection between the device and the testing equipment. Then, by rotating the knob 205, the threaded rod 204 and the knob 205 can rotate upward, so that the top end of the threaded rod 204 is threadedly connected to the top protective shell 203, thereby locking the bottom protective shell 203 and the top protective shell 203, which improves the protection effect at the connection between the sampling device and the testing equipment.
[0041] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A sampling device for a drug transdermal testing meter comprising a sampling housing (1), characterized in that: The upper and lower sides of the sampling shell (1) are rotatably connected to locking plates (3), and the adjacent sides of the two locking plates (3) are fixedly connected to fixing blocks (4). The front end of the inner wall of the sampling shell (1) is threadedly connected to a connecting shell (5). The rear side of the outer wall of the connecting shell (5) is provided with a threaded groove (6). The upper and lower sides of the connecting shell (5) are provided with locking grooves (7). The adjacent sides of the two fixing blocks (4) are respectively engaged with the corresponding locking grooves (7). The front end of the connecting shell (5) is connected to a conveying shell (8). The front end of the conveying shell (8) is connected to a sampling head (10). The middle of the adjacent sides of the two locking plates (3) is fixedly connected to a sealing shell (9). The adjacent sides of the two sealing shells (9) are engaged with the outer wall of the connecting shell (5). The rear end of the outer wall of the sampling shell (1) is provided with a protection mechanism (2). The protection mechanism (2) is used to protect the installation and connection position of the sampling device.
2. The sampling device for a transdermal drug testing apparatus according to claim 1, wherein: The protective mechanism (2) includes a fixing plate (201). The inner wall of the fixing plate (201) is fixedly connected to the rear end of the outer wall of the sampling shell (1). The left and right sides of the fixing plate (201) are rotatably connected to a rotating shaft (202). The outer wall of the rotating shaft (202) is rotatably connected to two protective shells (203). The top left and right sides of the bottom protective shell (203) are threadedly connected to threaded rods (204). The bottom end of the threaded rod (204) is fixedly connected to a knob (205). The top end of the threaded rod (204) is threadedly connected to the bottom of the top protective shell (203).
3. The sampling device for a transdermal testing instrument according to claim 2, characterized in that: The protective mechanism (2) also includes two rubber pads (206), with the opposite sides of the two rubber pads (206) respectively fixedly connected to the adjacent sides of the inner walls of the two protective shells (203).
4. The sampling device for a transdermal testing instrument according to claim 2, characterized in that: The top protective shell (203) has positioning posts (207) fixedly connected to the left and right sides of the bottom wall, and the bottom protective shell (203) has positioning grooves (208) on the left and right sides of the top rear side, with the bottom end of the positioning post (207) engaging with the positioning groove (208).
5. The sampling device for a transdermal testing instrument according to claim 2, characterized in that: The outer walls of both knobs (205) are fixedly connected with a plurality of protrusions (209), and the plurality of protrusions (209) are connected in an equidistant ring.
6. The sampling device for a transdermal drug testing apparatus according to claim 1, wherein: The outer wall of the sampling shell (1) is fixedly connected with multiple protective rings (11), and the multiple protective rings (11) are all connected at equal intervals.
7. The sampling device for a drug transdermal testing instrument according to claim 1, characterized in that: Multiple rubber blocks (12) are fixedly connected to the opposite sides of the two locking plates (3), and the multiple rubber blocks (12) are all rectangular in design.
8. The sampling device for a transdermal drug testing apparatus according to claim 1, wherein: A scale (13) is fixedly connected to the right side of the sampling shell (1), and the outer wall of the scale (13) is designed to be smooth.