Refrigeration equipment with rotating platform

Abstract

The utility model discloses refrigeration equipment with a rotating platform, and belongs to the technical field of biological experiment equipment. The refrigeration equipment with the rotating platform comprises a refrigerator, the refrigerator is provided with at least one refrigeration cavity, the refrigeration equipment further comprises a workbench slidably connected in the refrigeration cavity, the workbench is rotatably connected with a rotating shaft, the rotating shaft is fixedly connected with an overturning plate, and the overturning plate is provided with a positioning hole used for fixing a centrifugal tube; the magnetic frame is detachably mounted on the workbench and is arranged below the rotating shaft; according to the utility model, the workbench which is integrally designed with the refrigerator and can be pulled out or pushed into the refrigeration cavity is arranged, so that a centrifugal tube can be directly inserted into the positioning hole, and operations such as washing and the like can be completed by rotating and mixing the overturning plate and matching with the magnetic frame, so that the traditional operation needing to be transferred to an experiment is integrally completed; the transfer temperature fluctuation and sample pollution are avoided, and the convenience and high precision of an immune experiment are ensured.

Description

Technical Field

[0001] This utility model relates to the field of biological experimental equipment technology, and in particular to a refrigeration device with a rotating platform. Background Technology

[0002] In molecular biology experiments such as immunoprecipitation, samples in centrifuge tubes need to be mixed at low temperatures to ensure effective binding of proteins, antibodies, and magnetic beads, and to reduce non-specific binding.

[0003] In existing technologies, traditional experimental procedures require transferring samples between different devices, such as refrigerators or rooms at around 4 degrees Celsius, shakers, magnetic racks, etc. Due to the lack of integrated equipment, continuous experimental operations in low-temperature environments cannot be achieved, and frequent transfer operations are prone to sample contamination or temperature fluctuations, thus failing to meet the needs of high-precision immunoassay experiments. Utility Model Content

[0004] The purpose of this invention is to solve the problem that the lack of integrated equipment in low-temperature biological experiments in the prior art makes it difficult to meet the accuracy requirements of experimental operations, and to propose a refrigeration device with a rotating platform.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A refrigeration device with a rotating platform includes a refrigerator having at least one refrigeration cavity, and further includes: a worktable slidably connected within the refrigeration cavity, wherein a rotating shaft is rotatably connected to the worktable, a flip plate is fixedly connected to the rotating shaft, and the flip plate has positioning holes for fixing centrifuge tubes; and a magnetic frame detachably mounted on the worktable, the magnetic frame being disposed below the rotating shaft.

[0007] Preferably, a bracket is fixedly connected to the workbench, the rotating shaft is rotatably connected to the bracket, and a drive unit for driving the rotating shaft to rotate is provided inside the workbench.

[0008] To further improve the stability and speed controllability of rotation, the drive unit includes a motor fixedly connected to the workbench, a first pulley fixedly connected to the output end of the motor, and a second pulley fixedly connected to the rotating shaft. The first pulley is rotatably connected to the second pulley via a belt.

[0009] To improve experimental efficiency, preferably, the flipping plate is provided in multiple sets, and the multiple sets of flipping plates are distributed equidistantly on the cylindrical surface of the rotating shaft.

[0010] Preferably, the workbench is provided with a slot, and the bottom of the magnetic frame is fixedly connected with a card block, which is engaged in the slot.

[0011] To facilitate the handling of experimental samples, preferably, a guide groove is provided in the refrigeration chamber, and a roller is rotatably connected to the bottom of the worktable. When the worktable is moved, the roller rolls along the guide groove.

[0012] Compared with the prior art, the present invention provides a refrigeration device with a rotating platform, which has the following advantages:

[0013] 1. The refrigeration equipment with a rotating platform ensures the torque of the transmission power by using a first pulley with a smaller diameter than the second pulley. This ensures stable and reliable rotation while facilitating the control of the rotation speed of the tilting plate, thus meeting experimental requirements.

[0014] 2. This refrigeration equipment with a rotating platform has a slot on the worktable, and a locking block is fixedly connected to the bottom of the magnetic frame. The magnetic frame is locked into the slot by the locking block, thereby allowing the magnetic strength of the magnetic frame to be changed as needed, and facilitating disassembly and handheld use with centrifuge tubes.

[0015] All parts not covered in this device are the same as or can be implemented using existing technologies. This utility model sets up a worktable that can be pulled out or pushed into the refrigeration chamber by integrating it with the refrigerator. Centrifuge tubes can then be directly inserted into the positioning holes. The rotation of the flip plate mixes the samples, and the magnetic rack completes washing and other operations. This integrates the traditional operations that require transfer experiments, avoiding temperature fluctuations and sample contamination during transfer, and ensuring high precision in immunoassay experiments. Attached Figure Description

[0016] Figure 1 This is a perspective view of a refrigeration device with a rotating platform according to the present invention.

[0017] Figure 2 This is a schematic diagram showing the opening of a refrigeration device with a rotating platform according to the present invention.

[0018] Figure 3 This is a first-view perspective perspective view of a refrigeration equipment workbench with a rotating platform proposed in this utility model.

[0019] Figure 4 This is a second-view perspective perspective view of a refrigeration equipment workbench with a rotating platform proposed in this utility model.

[0020] Figure 5 This is a partial cross-sectional view of a refrigeration equipment workbench with a rotating platform proposed in this utility model.

[0021] In the diagram: 1. Refrigerator; 101. Door; 102. Guide groove; 2. Workbench; 201. Bracket; 202. Slot; 203. Roller; 3. Shaft; 301. Second pulley; 4. Flip plate; 401. Positioning hole; 5. Motor; 501. First pulley; 502. Belt; 6. Magnetic frame. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0023] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0024] Example:

[0025] Reference Figures 1-5 A refrigeration device with a rotating platform includes a refrigerator 1, which has at least one refrigeration compartment. The refrigerator 1 can be a small refrigerator with a double-layered insulated body (outer ABS engineering plastic, inner stainless steel), a volume of 50-80L, and an adjustable temperature range of 2-8℃. It should be suitable for placement on a laboratory table, with dimensions not exceeding 50cm in length, 50cm in width, and 80cm in height. The refrigerator 1 needs to be equipped with two to three refrigeration compartments, each with a hinged door 101 that can be sealed after experimental samples are placed inside. A workbench 2 is slidably installed in one of the refrigeration compartments. A speed-adjustable rotating shaft 3 is rotatably connected to the workbench 2, and a flipping plate 4 is fixedly connected to the rotating shaft 3. The flipping plate 4 has positioning holes 401 for fixing centrifuge tubes. Experimental samples, such as centrifuge tubes, are inserted into the positioning holes 401 and then rotated clockwise or counterclockwise under the drive of the rotating shaft 3 for mixing. A magnetic frame 6 is installed directly below the rotating shaft 3 to assist in the complete immunoprecipitation experiment in an integrated manner.

[0026] In the above design, by setting up a worktable 2 that can be pulled out or pushed into the refrigeration chamber and is integrated with the refrigerator 1, centrifuge tubes can be directly inserted into the positioning hole 401. The rotation of the flip plate 4 is used for mixing, and the washing and other operations are completed with the help of the magnetic rack 6. This integrates the traditional operations that require transfer experiments, avoids temperature fluctuations and sample contamination during transfer, and ensures high precision in immunoassay experiments.

[0027] Specifically, a bracket 201 is fixedly connected to the workbench 2, and a rotating shaft 3 is rotatably connected to the bracket 201. A motor 5 for driving the rotating shaft 3 is installed inside the workbench 2. Here, the output end of the variable frequency or variable voltage motor 5, which can change the speed, is fixedly connected to a first pulley 501. A second pulley 301 is fixedly connected to the rotating shaft 3. The first pulley 501 is rotatably connected to the second pulley 301 through a belt 502. The diameter of the first pulley 501 is smaller than that of the second pulley 301, thereby ensuring the torque of the transmission power and ensuring stable and reliable rotation. At the same time, it is convenient to control the rotation speed of the flip plate 4 at any time to ensure the experimental requirements.

[0028] Here, three sets of flip plates 4 are provided, and the three sets of flip plates 4 are distributed equidistantly on the cylindrical surface of the rotating shaft 3, which can accommodate more centrifuge tubes. The positioning holes 401 have different diameters, which can accommodate centrifuge tubes of different diameters. The number of positioning holes 401 is 3-24, with 12 or 24 being appropriate in actual experiments to meet experimental requirements.

[0029] By opening a slot 202 on the workbench 2, a locking block is fixedly connected to the bottom of the magnetic rack 6. The magnetic rack 6 is locked in the slot 202 by the locking block, so that the magnetic strength of the magnetic rack 6 can be changed as needed, and it is convenient to disassemble and use with centrifuge tubes. The specific magnetic strength is ≥0.3T, which is compatible with 1.5mL / 2mL magnetic bead separation tubes.

[0030] Specifically, a guide groove 102 is provided in the refrigeration chamber, and four sets of rollers 203 are rotatably connected to the bottom of the workbench 2. When the workbench 2 is moved, the rollers 203 can roll along the guide groove 102, which makes it easy to pull the workbench 2 out or push it in, and to take out and place centrifuge tubes.

[0031] In this invention, centrifuge tubes of the corresponding diameter are inserted into the positioning hole 401 and fixed. The door 101 is closed, and the motor 5 is started to drive the rotating shaft 3 to rotate. The centrifuge tubes are then tumbled and mixed in the refrigeration chamber via the flip plate 4. Generally, the mixing takes place at 4°C for 1-2 hours. Then, the workbench 2 is pulled out. At this point, the workbench 2 is not completely pulled out of the refrigeration chamber, but about two-thirds of it is pulled out, so that the entire flip plate 4 is still in the area where the refrigeration chamber emits cold air. This ensures that the surrounding temperature does not fluctuate too much when separating the magnetic beads, thereby improving the high precision of the experimental process. During separation, the magnetic rack 6 can be removed for operation, or the centrifuge tubes can be adjusted to be positioned above the magnetic rack 6 for operation. The main point is that the magnetic beads gather on one side of the centrifuge tube under the action of the magnetic field to facilitate the separation operation.

[0032] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A refrigeration device with a rotating platform, comprising a refrigerator (1), the refrigerator (1) having at least one refrigeration compartment, characterized in that, Also includes: The worktable (2) is slidably connected inside the refrigeration chamber. The workbench (2) is rotatably connected to a rotating shaft (3), and a flip plate (4) is fixedly connected to the rotating shaft (3). The flip plate (4) is provided with a positioning hole (401) for fixing the centrifuge tube. A magnetic rack (6) is detachably mounted on the workbench (2), and the magnetic rack (6) is located below the rotating shaft (3).

2. A refrigeration device with a rotating platform according to claim 1, characterized in that, A bracket (201) is fixedly connected to the workbench (2), and the rotating shaft (3) is rotatably connected to the bracket (201). A drive unit for driving the rotating shaft (3) to rotate is provided inside the workbench (2).

3. A refrigeration device with a rotating platform according to claim 2, characterized in that, The drive unit includes a motor (5) fixedly connected in the workbench (2), the output end of the motor (5) is fixedly connected to a first pulley (501), and a second pulley (301) is fixedly connected on the rotating shaft (3). The first pulley (501) is rotatably connected to the second pulley (301) through a belt (502).

4. A refrigeration device with a rotating platform according to claim 1, characterized in that, The flip plate (4) is provided in multiple sets, and the multiple sets of flip plates (4) are distributed equidistantly on the cylindrical surface of the rotating shaft (3).

5. A refrigeration device with a rotating platform according to claim 1, characterized in that, The workbench (2) is provided with a slot (202), and a card block is fixedly connected to the bottom of the magnetic frame (6), and the card block is engaged in the slot (202).

6. A refrigeration device with a rotating platform according to claim 1, characterized in that, The refrigeration chamber is provided with a guide groove (102), and the bottom of the worktable (2) is rotatably connected with a roller (203). When the worktable (2) is moved, the roller (203) rolls along the guide groove (102).

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