Cross contamination prevention ventilation structure of pharmacokinetic metabolism cage
By installing partitions and a one-way valve solenoid valve system within the pharmacokinetics metabolism cage, independent air management was achieved, solving the problem of cross-contamination and improving the accuracy of experimental data.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- XIHUA (TAICANG) NEW DRUG DEV CO LTD
- Filing Date
- 2025-05-07
- Publication Date
- 2026-05-15
AI Technical Summary
In the ventilation structure of traditional pharmacokinetic metabolism cages, cross-contamination of air between cages can easily occur, affecting the accuracy of experimental data.
The pharmacokinetics metabolism cage is divided into multiple independent zones using a partition rack. Each zone's exhaust is controlled by a one-way valve and a solenoid valve. Combined with independent exhaust pipes and a filtration system, this ensures that the air does not contaminate each zone.
This effectively avoids cross-contamination of the air and improves the accuracy and reliability of experimental data.
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Figure CN224234438U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmacokinetic testing technology, and in particular to a cross-contamination prevention and ventilation structure for a pharmacokinetic metabolism cage. Background Technology
[0002] Pharmacokinetics, or pharmacodynamics for short, primarily studies the dynamic changes in how the body processes drugs. This includes the absorption, distribution, biochemical transformation, and excretion of drugs within the body, particularly the changes in blood drug concentration over time. Drug metabolism is related to factors such as age, sex, individual differences, and genetic factors.
[0003] A pharmacokinetic metabolic cage is an experimental device used to study the metabolic processes of drugs in living organisms. By simulating the environment inside a living organism, it helps researchers better understand the absorption, distribution, metabolism, and excretion of drugs in the body.
[0004] The ventilation structure of traditional pharmacokinetic metabolism cages is generally connected by a main pipe and branch pipes for each metabolism cage. During the ventilation process, the air exhausted from each metabolism cage is prone to cross-contamination, which affects the accuracy of experimental data.
[0005] Therefore, it is necessary to provide a cross-contamination prevention and ventilation structure for a pharmacokinetic metabolism cage to solve the above-mentioned technical problems. Utility Model Content
[0006] This invention provides a cross-contamination prevention ventilation structure for pharmacokinetics metabolism cages, solving the problem that cross-contamination of air can easily occur when multiple metabolism cages are ventilated through interconnected main pipes and branch pipes, affecting the accuracy of experimental data.
[0007] To solve the above-mentioned technical problems, this utility model provides a cross-contamination prevention and ventilation structure for a pharmacokinetics metabolism cage, comprising: a metabolism cage;
[0008] A partition frame is installed inside the cage. Multiple exhaust pipes are installed on the back of the cage. A first one-way valve is fixedly connected to one end of the back of each exhaust pipe. A solenoid valve is installed on the other end of each first one-way valve. A connecting pipe is installed on the other end of each solenoid valve. A filter assembly is installed on the top of the cage. An exhaust pipe is installed on the back of the filter assembly through a connecting pipe. An exhaust assembly is installed on the top of the cage.
[0009] Multiple sealed doors are rotatably connected to the front of the partition frame via a rotating structure. A disinfection lamp is installed on the back of each sealed door. A cabinet door is rotatably connected to the front of the cage, and an air inlet pipe is installed on the front of the cabinet door.
[0010] The partition rack divides the interior of the enclosure into multiple independent areas. Multiple exhaust pipes correspond to the multiple areas inside the enclosure. The other end of the connecting pipe is connected to the exhaust pipe. The inlet of the exhaust assembly is connected to the filter assembly. The sealing door seals the area separated by the partition rack. If necessary, a hole can be opened on the sealing door to allow air to enter. Since the air is discharged from the exhaust pipe, opening a hole on the sealing door will not cause cross-contamination of the air inside the different areas.
[0011] Preferably, a support frame is installed at the bottom of the cage, the support frame includes a base plate and an anti-slip pad, and a handle is installed on the front of each of the sealed doors; the anti-slip pad is located at the bottom of the base plate near the four corners and mainly serves to prevent slipping.
[0012] Preferably, a control box with a door is installed on one side of the cage, and an operation panel is installed on the other side of the cage via a mounting base; the operation panel can set the equipment operating parameters.
[0013] Preferably, a second one-way valve is installed at the other end of the air intake pipe, and a filter pipe is installed at the other end of the second one-way valve through a valve, and a filter structure is installed inside the filter pipe.
[0014] Preferably, the exhaust assembly includes a protective shell, an exhaust pipe, an exhaust component, and a mounting pipe, wherein the mounting pipe is used to connect the inlet of the exhaust component and the filter assembly; the exhaust component is a device that provides suction, such as a separate unit.
[0015] Preferably, the filter assembly includes a filter box and an interceptor component for filtering dust and odors; the top of the filter box is fitted with a lid.
[0016] Compared with related technologies, this utility model has the following beneficial effects:
[0017] To reduce cross-contamination during the ventilation process of metabolic cages and improve the accuracy of experimental data, this invention divides the interior of a large metabolic cage into multiple spaces using a partition frame. An exhaust pipe equipped with a first one-way valve is installed at each of the partitioned spaces on the back of the cage. The first one-way valve ensures that air can only exit through the exhaust pipe, preventing air from flowing back into the cage. Each first one-way valve is equipped with a solenoid valve at the other end, allowing precise control of the exhaust in the corresponding space. By connecting the exhaust pipe to the corresponding solenoid valve via a connecting pipe, multiple spaces can be ventilated simultaneously when the exhaust assembly provides suction. This design divides the interior of the metabolic cage into multiple independent ventilation zones, each corresponding to an experimental animal space with an independent air duct design. The precise control of the exhaust zone by the first one-way valve and solenoid valve avoids cross-contamination during the exhaust process of multiple metabolic cages, thus improving the accuracy of experimental data. Attached Figure Description
[0018] Figure 1 A schematic diagram of a preferred embodiment of the cross-contamination prevention ventilation structure of the pharmacokinetics metabolism cage provided by this utility model;
[0019] Figure 2 A schematic diagram of the operation screen is provided for this utility model;
[0020] Figure 3 A schematic diagram of the intake pipe is provided for this utility model;
[0021] Figure 4 Provided for this utility model Figure 3 An enlarged view of point A shown;
[0022] Figure 5 A schematic diagram of the exhaust component is provided for this utility model.
[0023] The diagram is labeled as follows: 1. Support frame, 101. Base plate, 102. Anti-slip mat, 2. Control box, 3. Box door, 4. Cage, 5. Cabinet door, 6. Connecting pipe, 7. Filter assembly, 701. Filter box, 702. Interception component, 8. Exhaust assembly, 801. Protective shell, 802. Exhaust pipe two, 803. Exhaust component, 804. Mounting pipe, 9. Operation panel, 10. Mounting base, 11. First one-way valve, 12. Solenoid valve, 13. Exhaust pipe one, 14. Connecting pipe, 15. Exhaust duct, 16. Sealing door, 17. Disinfection lamp, 18. Divider frame, 19. Rotating structure, 20. Handle, 21. Inlet pipe, 22. Filter pipe, 23. Second one-way valve, 24. Filter structure, 25. Valve. Detailed Implementation
[0024] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0025] Please refer to the following: Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 ,in, Figure 1 A schematic diagram of a preferred embodiment of the cross-contamination prevention ventilation structure of the pharmacokinetics metabolism cage provided by this utility model; Figure 2 A schematic diagram of the operation screen is provided for this utility model; Figure 3 A schematic diagram of the intake pipe is provided for this utility model; Figure 4 Provided for this utility model Figure 3 An enlarged view of point A shown; Figure 5 A schematic diagram of the exhaust component is provided for this utility model.
[0026] A cross-contamination prevention and ventilation structure for a pharmacokinetic metabolism cage includes: a metabolism cage 4;
[0027] A partition frame 18 is installed inside the cage 4. Multiple exhaust pipes 13 are installed on the back of the cage 4. A first one-way valve 11 is fixedly connected to one end of the back of each exhaust pipe 13. A solenoid valve 12 is installed on the other end of each first one-way valve 11. A connecting pipe 14 is installed on the other end of each solenoid valve 12. A filter assembly 7 is installed on the top of the cage 4. An exhaust pipe 15 is installed on the back of the filter assembly 7 through a connecting pipe 6. An exhaust assembly 8 is installed on the top of the cage 4.
[0028] Multiple sealed doors 16 are rotatably connected to the front of the partition frame 18 via a rotating structure 19. A disinfection lamp 17 is installed on the back of each sealed door 16. A cabinet door 5 is rotatably connected to the front of the cabinet 4. An air inlet pipe 21 is installed on the front of the cabinet door 5.
[0029] The partition frame 18 divides the interior of the cage 4 into multiple independent areas. Multiple exhaust pipes 13 correspond to multiple areas inside the cage 4. The other end of the connecting pipe 14 is connected to the exhaust pipe 15. The inlet of the exhaust assembly 8 is connected to the filter assembly 7. The sealing door 16 seals the areas separated by the partition frame 18 separately. If necessary, a hole can be opened on the sealing door 16 to facilitate air entry. Since the air is discharged from the exhaust pipe 13, the opening on the sealing door 16 will not cause cross-contamination of the air inside the different areas. The air inlet pipe 21 facilitates the entry of air into the interior of the cage 4. The disinfection lamp 17 can disinfect the areas separated inside the cage 4 when needed.
[0030] The bottom of the cage 4 is equipped with a support frame 1, which includes a base plate 101 and an anti-slip pad 102. Each sealed door 16 has a handle 20 installed on its front.
[0031] The anti-slip mat 102 is located at the bottom of the base plate 101 near the four corners and mainly serves to prevent slipping. The top of the base plate 101 is connected to the top of the cage 4, and the handle 20 makes it easy to open the sealed door 16.
[0032] A control box 2 with a door 3 is installed on one side of the cage 4, and an operation panel 9 is installed on the other side of the cage 4 via a mounting base 10;
[0033] The operation panel 9 can set the equipment operating parameters. The door 3 is equipped with a lock. The control box 2 contains a power switch and a controller for controlling the operation of the equipment.
[0034] A second one-way valve 23 is installed at the other end of the intake pipe 21. A filter pipe 22 is installed at the other end of the second one-way valve 23 through a valve 25. A filter structure 24 is installed inside the filter pipe 22.
[0035] Filter structure 24 is a structure that can filter dust.
[0036] The exhaust assembly 8 includes a protective housing 801, an exhaust pipe 802, an exhaust component 803, and a mounting pipe 804, which is used to connect the inlet of the exhaust component 803 and the filter assembly 7.
[0037] The exhaust component 803 is a device that provides suction, such as an exhaust pipe 802, and a duct connection to the exhaust channel.
[0038] Filter assembly 7 includes filter box 701 and interception component 702, the interception component 702 being used to filter dust and odors;
[0039] The top of the filter box 701 is fitted with a cover, and the interception component 702 can filter out odors and dust.
[0040] The working principle of this utility model is as follows:
[0041] A large cabinet 4 is divided into multiple spaces by a partition frame 18. An exhaust pipe 13 with a first one-way valve 11 is installed at each of the spaces on the back of the cabinet 4. The first one-way valve 11 ensures that air can only be discharged through the exhaust pipe 13, preventing air from the exhaust pipe 15 from flowing back into the cabinet 4. Each first one-way valve 11 is equipped with a solenoid valve 12 at the other end, allowing precise control of the exhaust from the corresponding space. The exhaust pipe 15 and the corresponding solenoid valve 12 are connected via a connecting pipe 14. When the exhaust assembly 8 provides suction, air can be exhausted from multiple spaces simultaneously. In actual use, the exhaust assembly 8 provides suction to exhaust air from multiple spaces within the cabinet 4. During this process, the first one-way valve 11, in conjunction with the solenoid valve 12, precisely controls which space is ventilated and prevents air backflow. The exhausted air is filtered by the filter assembly 7 before being discharged. During the exhaust process, the air inlet pipe 21 on the cabinet door 5 draws clean external air into the cabinet 4.
[0042] The above are merely embodiments of this utility model and do not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the description and drawings of this utility model, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.
Claims
1. A cross-contamination prevention ventilation structure for a pharmacokinetic metabolism cage, characterized in that, include: Xie Long (4); A partition frame (18) is installed inside the cage (4). Multiple exhaust pipes (13) are installed on the back of the cage (4). A first one-way valve (11) is fixedly connected to one end of the back of each exhaust pipe (13). A solenoid valve (12) is installed at the other end of each first one-way valve (11). A connecting pipe (14) is installed at the other end of each solenoid valve (12). A filter assembly (7) is installed on the top of the cage (4). An exhaust pipe (15) is installed on the back of the filter assembly (7) through a connecting pipe (6). An exhaust assembly (8) is installed on the top of the cage (4). Multiple sealed doors (16) are rotatably connected to the front of the partition frame (18) via a rotating structure (19). Each sealed door (16) is equipped with a disinfection lamp (17) on its back. The front of the cabinet (4) is rotatably connected to a cabinet door (5), and an air inlet pipe (21) is installed on the front of the cabinet door (5).
2. The cross-contamination prevention ventilation structure of the pharmacokinetic metabolism cage according to claim 1, characterized in that, The bottom of the cage (4) is equipped with a support frame (1), which includes a base plate (101) and an anti-slip pad (102). Each of the sealing doors (16) is equipped with a handle (20) on its front.
3. The cross-contamination prevention ventilation structure of the pharmacokinetic metabolism cage according to claim 1, characterized in that, A control box (2) with a door (3) is installed on one side of the cage (4), and an operation panel (9) is installed on the other side of the cage (4) via a mounting base (10).
4. The cross-contamination prevention ventilation structure of the pharmacokinetic metabolism cage according to claim 1, characterized in that, The other end of the intake pipe (21) is equipped with a second one-way valve (23), and the other end of the second one-way valve (23) is equipped with a filter pipe (22) through a valve (25). The filter pipe (22) is equipped with a filter structure (24).
5. The cross-contamination prevention ventilation structure of the pharmacokinetic metabolism cage according to claim 1, characterized in that, The exhaust assembly (8) includes a protective shell (801), an exhaust pipe (802), an exhaust component (803), and an installation pipe (804), the installation pipe (804) being used to connect the inlet of the exhaust component (803) and the filter assembly (7).
6. The cross-contamination prevention ventilation structure of the pharmacokinetic metabolism cage according to claim 1, characterized in that, The filter assembly (7) includes a filter box (701) and an interception component (702) for filtering dust and odors.