An acetylcysteine solution production reactor for inhalation
By introducing a buffer base structure into the reactor, the instability problem of the stirring shaft was solved, improving the stability of the equipment and product quality, and extending the service life of key components.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANDONG XINHUA LUKANG PHARM CO LTD
- Filing Date
- 2025-07-09
- Publication Date
- 2026-05-29
Smart Images

Figure CN224293273U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of acetylcysteine solution production technology, specifically to a reaction vessel for producing an inhaled acetylcysteine solution. Background Technology
[0002] Acetylcysteine inhalation solution is an important expectorant widely used in the treatment of respiratory diseases. Its production process typically involves dissolving, mixing, and reacting raw materials under specific conditions, such as controlled temperature and pH levels. These steps are mainly completed in a reactor equipped with a stirring device. In existing technology, the reactor used to produce acetylcysteine inhalation solution typically includes a reactor body, a drive motor, a transmission device, and a stirring shaft extending into the reactor body. The stirring shaft is equipped with stirring blades, and the drive motor drives the stirring shaft to rotate via the transmission device. This causes the blades to stir the materials (mainly aqueous solutions or buffer solutions containing acetylcysteine) inside the reactor to achieve dissolution, uniform mixing, promote reaction, or prevent precipitation.
[0003] However, during the production process of acetylcysteine solution for inhalation, especially at higher concentrations or specific temperatures, its fluid properties, such as viscosity and flowability, may change. The stirring process encounters significant resistance. Existing reactor stirring structures present a significant technical problem in practice: the stirring shaft is prone to instability during operation, particularly generating unexpected radial oscillations or vibrations. This instability of the stirring shaft is transmitted in reverse through the coupling to the output shaft of the drive motor, generating harmful shear forces and accelerating equipment wear and damage. Utility Model Content
[0004] To address the aforementioned problems, the main objective of this invention is to provide a reaction vessel for producing acetylcysteine solution for inhalation, which enhances the stability of the stirring shaft, preventing it from being subjected to large rigid forces when encountering significant resistance during stirring, and also preventing harmful shear forces on the output shaft of the drive motor.
[0005] To achieve the above objectives, this utility model provides a reaction vessel for producing an inhaled acetylcysteine solution, comprising a reaction vessel body, a cover, a support frame, and a stirring device. The reaction vessel body is fixed on the support frame, the cover is located at the upper end of the reaction vessel, a fixed plate is provided on the outer periphery below the reaction vessel body, the upper end of the support frame is connected to the fixed plate, and the stirring device includes a drive motor, a coupling, a stirring shaft, stirring blades, and a buffer base. The buffer base includes an annular body, a connecting rod, an inner ring, a support column, and an elastic element. The top surface of the support column is provided with an inner groove, and the outer periphery of the lower end of the support column is provided with an annular groove.
[0006] Preferably, the cover is fastened to the reactor body, and the cover and the interior of the reactor body form a reaction space. A platform is provided on the top surface of the cover, and the drive motor is fixed on the platform.
[0007] Preferably, the platform is provided with a perforation, the output end of the drive motor passes through the perforation and is located in the reaction space, the output end of the drive motor is connected to a coupling, and the output end of the coupling is rotatably connected to the upper end of the stirring shaft.
[0008] Preferably, the stirring blade is a rotating blade, and the stirring blade is fixed on the outer wall of the stirring shaft.
[0009] Preferably, the lower end of the reactor body is provided with an inverted cone shape, the bottom of the inverted cone shape is provided with a discharge port, a discharge pipe is connected to the discharge port, and a switch valve is provided on the discharge pipe.
[0010] Preferably, the annular body is located at the upper end of the inverted cone, the inner ring is located at the center of the annular body, and there are multiple connecting rods, which are evenly distributed in a circle between the annular body and the inner ring.
[0011] Preferably, the elastic element is located inside the built-in groove, with its lower end connected to the bottom of the built-in groove and its upper end connected to the bottom surface of the stirring shaft, and the lower end of the stirring shaft located inside the built-in groove.
[0012] Preferably, the built-in ring is rotatably fitted inside the annular groove.
[0013] The beneficial effects of this utility model through the above technical solution include: the reaction vessel of this utility model is equipped with a stirring device, and the stirring device is equipped with a buffer base. The buffer base can improve the stability of the stirring shaft, effectively suppress the radial sway and vibration of the stirring shaft during operation, significantly reduce or even eliminate the shear stress transmitted to the output end of the drive motor, thereby improving the stability and reliability of equipment operation, extending the life of key components, and ensuring the continuity of the production of acetylcysteine solution for inhalation and product quality; in addition, the buffer base is also equipped with an elastic element, which can buffer the external force on the longitudinal direction of the stirring shaft. Attached Figure Description
[0014] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments.
[0015] Figure 1 This is a schematic diagram of the structure of the reaction vessel for producing acetylcysteine solution for inhalation according to this utility model.
[0016] Figure 2 This is a schematic diagram of the stirring device in the reactor for producing an inhaled acetylcysteine solution according to this utility model.
[0017] Figure 3 This is the utility model Figure 2A top view of the stirring device.
[0018] Figure 4 This is the utility model Figure 3 A schematic diagram of the cross section of AA'.
[0019] Explanation of reference numerals in the attached figures
[0020] 10. Reactor body; 11. Fixed plate; 12. Inverted cone shape; 13. Discharge port; 14. Feed pipe; 15. Switch valve; 20. Cover; 21. Feed inlet; 22. Flange; 30. Support frame; 41. Drive motor; 42. Coupling; 43. Stirring shaft; 44. Stirring blade; 45. Buffer base; 51. Annular body; 52. Connecting rod; 53. Internal ring; 54. Support column; 541. Internal groove; 542. Annular groove; 55. Elastic element. Detailed Implementation
[0021] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Many specific details are set forth in the following description to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.
[0022] like Figure 1 The diagram shows the structure of the reactor for producing acetylcysteine solution for inhalation according to this invention. The reactor includes a reactor body 10, with a cover 20 at the upper end of the reactor body 10. The cover 20 is fastened to the reactor body 10. More preferably, the cover 20 and the reactor body 10 are connected by a flange 22. The cover 20 and the reactor body 10 form a reaction space, which is used for the production reaction of the acetylcysteine solution for inhalation. The cover 20 has a feed inlet 21 through which the raw materials and reagents for the reaction enter the reaction space. Additionally, the reactor body 10 has an inverted conical body 12 at its bottom, with a discharge port 13 at its bottom. A discharge pipe 14 is connected to the discharge port 13, and a switching valve 15 is installed on the discharge pipe 14 to control the start and stop of the acetylcysteine solution discharge from the discharge port 13.
[0023] Please continue reading. Figure 1As shown, the reactor of this utility model is also provided with a support frame 30, and the reactor body 10 is fixed on the support frame 30. Specifically, a fixing plate 11 is provided on the outer periphery below the reactor body 10, and the upper end of the support frame 30 is connected to the fixing plate 11, thereby stably supporting the reactor body 10. In other embodiments, a base plate can also be provided at the bottom of the support frame 30. The base plate has a large cross-section, thereby further improving the supporting force of the support frame 30 on the reactor body 10 and preventing the reactor body 10 from tipping over when subjected to vibration or shaking.
[0024] In addition, such as Figure 1 and Figure 2 As shown, the reaction vessel of this utility model is also equipped with a stirring device, which includes a drive motor 41, a coupling 42, a stirring shaft 43, stirring blades 44, and a buffer base 45. The top surface of the cover 20 of this utility model is provided with a platform (not shown in the figure). The drive motor 41 is fixed on the platform, and the platform is provided with a through hole (not shown in the figure). The output end of the drive motor 41 passes through the through hole and is located in the reaction space. The output end of the drive motor 41 is connected to the coupling 42 after passing through the through hole. The output end of the coupling 42 is rotatably connected to the upper end of the stirring shaft 43. In addition, the stirring blades 44 are rotating blades and are fixed on the outer wall of the stirring shaft 43.
[0025] During use, the stirring device of this utility model, after starting the drive motor 41, the drive motor 41 and the coupling 42 work together to drive the stirring shaft 43 to rotate, thereby realizing the stirring, dissolving and reaction of the acetylcysteine solution in the reaction space inside the reactor body 10. In this embodiment, the bottom of the reactor body 10 is provided with an inverted cone 12, which facilitates the smooth discharge of material from the bottom. However, the bottom of the stirring shaft 43 does not touch the bottom, so the stirring shaft 43 is not stable during the rotation and stirring process. If the bottom of the reactor body 10 is a flat structure, the stirring shaft 43 can be stably supported, but the flat bottom is not conducive to the smooth flow of material in the reactor body 10, especially at the bottom, which is easy to form residue at the bottom and cause inconvenience in cleaning. Therefore, the stirring device of this utility model is provided with a buffer base 45, which can improve the stability of the stirring shaft 43 without affecting the discharge of material in the inverted cone 12. The specific structure of the buffer base 45 is as follows.
[0026] Please continue reading. Figures 2-4As shown, the buffer base 45 of this utility model is located at the lower end of the stirring shaft 43. The buffer base 45 is provided with an annular body 51, multiple connecting rods 52, an inner ring 53, a support column 54, and an elastic element 55. The annular body 51 is located at the upper end of the inverted cone 12. In other words, the annular body 51 is stably locked at the upper port of the inverted cone 12. Since the cross-sectional diameter of the inverted cone 12 gradually decreases from top to bottom, the annular body 51 is relatively stable inside the inverted cone 12 and will not fall. The inner ring 53 is located at the center of the annular body 51, and multiple connecting rods 52 are evenly distributed in a circle between the annular body 51 and the inner ring 53. In this embodiment, there are three connecting rods 52. One end of the three connecting rods 52 is fixedly connected to the inner wall of the annular body 51, and the other end is fixedly connected to the outer wall of the inner ring 53.
[0027] In addition, such as Figure 4 As shown, the top surface of the support column 54 of this utility model is provided with an internal groove 541. The elastic element 55 can be a spring. The elastic element 55 is located at the bottom of the internal groove 541, and the bottom of the elastic element 55 is connected to the bottom surface of the internal groove 541. The lower end of the stirring shaft 43 is connected to the elastic element 55, and the lower end part of the structure of the stirring shaft 43 is located in the internal groove 541. When the stirring shaft 43 is subjected to an external force in its length direction, the elastic element 55 can provide a buffer force to prevent the stirring shaft 43 from being damaged by a rigid force in the longitudinal direction.
[0028] Furthermore, the lower end of the support column 54 of this utility model is provided with an annular groove 542, and the inner ring 53 is rotatably fitted in the annular groove 542. When the drive motor 41 drives the stirring shaft 43 to rotate and stir, the stirring shaft 43, together with the support column 54 and the elastic element 55, rotates at the same time. Since the inner ring 53 is engaged in the annular groove 542, it can prevent the stirring shaft 43 from deviating from its central axis position when rotating, and thus generating harmful shear force on the output shaft of the drive motor 41, causing it to be damaged. In addition, the stirring shaft 43 is pressed into the inner groove 541 by the elastic element 55, which can stably press the annular body 51 onto the inverted conical body 12, preventing the annular body 51 from deviating upward from its original position.
[0029] Through the above technical solution, the beneficial effects of this utility model include: the reaction vessel of this utility model is equipped with a stirring device, and the stirring device is equipped with a buffer base 45. The buffer base 45 can improve the stability of the stirring shaft 43, effectively suppress the radial sway and vibration of the stirring shaft 43 during operation, significantly reduce or even eliminate the shear stress transmitted to the output end of the drive motor 41, thereby improving the stability and reliability of equipment operation, extending the life of key components, and ensuring the continuity of the production of acetylcysteine solution for inhalation and product quality; in addition, the buffer base 45 is also equipped with an elastic element 55, which can buffer the external force in the longitudinal direction of the stirring shaft 43.
[0030] Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without inventive effort are within the scope of protection of this utility model.
Claims
1. A reaction vessel for producing acetylcysteine solution by inhalation, characterized in that, The reactor includes a reactor body (10), a cover (20), a support frame (30), and a stirring device. The reactor body (10) is fixed on the support frame (30). The cover (20) is located at the upper end of the reactor. A fixed plate (11) is provided on the outer periphery below the reactor body (10). The upper end of the support frame (30) is connected to the fixed plate (11). The stirring device includes a drive motor (41), a coupling (42), a stirring shaft (43), a stirring blade (44), and a buffer base (45). The buffer base (45) includes an annular body (51), a connecting rod (52), an inner ring (53), a support column (54), and an elastic element (55). The top surface of the support column (54) is provided with an inner groove (541), and the outer periphery of the lower end of the support column (54) is provided with an annular groove (542).
2. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 1, characterized in that, The cover (20) is fastened to the reactor body (10), and the cover (20) and the reactor body (10) form a reaction space. The top surface of the cover (20) is provided with a platform, and the drive motor (41) is fixed on the platform.
3. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 2, characterized in that, The platform is provided with a perforation, and the output end of the drive motor (41) passes through the perforation and is located in the reaction space. The output end of the drive motor (41) is connected to the coupling (42), and the output end of the coupling (42) is rotatably connected to the upper end of the stirring shaft (43).
4. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 1, characterized in that, The stirring blade (44) is a rotating blade, and the stirring blade (44) is fixed on the outer wall of the stirring shaft (43).
5. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 1, characterized in that, The lower end of the reactor body (10) is provided with an inverted cone (12), the bottom of the inverted cone (12) is provided with a discharge port (13), the discharge port (13) is connected to a feed pipe (14), and the feed pipe (14) is provided with a switch valve (15).
6. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 5, characterized in that, The annular body (51) is located at the upper end of the inverted cone (12), the inner ring (53) is located at the center of the annular body (51), and there are multiple connecting rods (52), which are evenly distributed in a circle between the annular body (51) and the inner ring (53).
7. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 1, characterized in that, The elastic element (55) is located in the built-in groove (541). The lower end of the elastic element (55) is connected to the bottom of the built-in groove (541), and the upper end is connected to the bottom surface of the stirring shaft (43). The lower end of the stirring shaft (43) is located in the built-in groove (541).
8. The reaction vessel for producing acetylcysteine solution for inhalation according to claim 1, characterized in that, The built-in ring (53) is rotatably fitted inside the annular groove (542).