Novel fine tissue storage device

By designing a specimen box with a grid structure and counterweights, the problems of small tissues detaching from the fixative during transportation and the cumbersome operation were solved, achieving stable immersion and simplifying the operation, thus improving the accuracy of pathological diagnosis.

CN224356907UActive Publication Date: 2026-06-16THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIV
Filing Date
2025-07-16
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

Existing small tissue storage devices are prone to causing tissue to detach from the fixative during transportation, are cumbersome to operate, have poor water permeability, and affect the accuracy of pathological diagnosis.

Method used

Design a storage device comprising specimen bottles and specimen boxes. The specimen boxes have a grid structure and counterweights to ensure that they are immersed in fixative in any placement position, and the permeability is improved by embedding paper, simplifying the operation process.

🎯Benefits of technology

It enables stable immersion of small tissues in fixative, simplifies the operation process, improves water permeability, reduces tissue damage and the risk of missed diagnosis, and enhances the accuracy of pathological diagnosis.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a novel small tissue storage device, so that small tissue can be fixed in formalin fixing liquid all the time, and it is more simple to take and place, and the water permeability is better. The novel small tissue storage device comprises a specimen bottle and a specimen box. The specimen bottle comprises a bottle body and a bottle cap which can be opened and closed in cooperation. The specimen box comprises a box body and a box cover which can be opened and closed in cooperation. The box body comprises five surfaces of front, back, left, right and bottom of the specimen box. The box cover is the top surface of the specimen box. The left, right and front surfaces of the box body are provided with grid structures. The bottom surface of the box body and the middle of the box cover are hollowed out and connected with embedding paper. A counterweight is inlaid in the back surface of the box body. The utility model focuses on using embedding paper to improve the water permeability of the specimen box, and the weight of the counterweight is used to ensure that the specimen box is always immersed in the fixing liquid of the specimen bottle.
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Description

Technical Field

[0001] This utility model belongs to the field of medical device technology, and specifically refers to a novel small tissue storage device. Background Technology

[0002] Small tissues, such as those obtained through fine-needle aspiration and endoscopic biopsy, are referred to as "small tissues" in pathology due to their minute size. Currently, small tissues are typically placed directly into simple capped vials containing formalin fixative, labeled, and sent to the pathology department. After verifying and receiving the specimen, the pathologist opens the vial, uses forceps to pick up the small tissue, wraps it in embedding paper, and places it in a specialized embedding cassette for fixation, dehydration, clearing, and paraffin embedding. The following industry pain points exist in the storage device for such small tissues and its subsequent transportation and sampling: (1) During transportation, due to shaking, small tissues may stick to the bottle cap and other parts and be removed from the soaking of formalin fixative, resulting in the specimen not being effectively fixed and causing tissue autolysis, which seriously affects the subsequent pathological diagnosis; (2) During the process of pathologists picking up small tissues, small tissues that are too small in volume will inevitably be missed, resulting in missed diagnosis; (3) The process of picking up small tissues with forceps will cause compression of small tissues, affecting the accuracy of small tissue pathological diagnosis.

[0003] Utility model patent CN215454957U discloses a "Small Tissue Storage Device," which improves upon existing specimen bottles. The device includes a specimen bottle, a limiting basket, a specimen box, and a connecting rod. The connecting rod and limiting basket confine the specimen box to the bottom of the specimen bottle. The limiting basket has a grid design on all four sides (front, back, left, and right), and the specimen box also has a mesh structure around its perimeter. The lid of the specimen box is made of transparent, colorless plastic. This patent ensures that small tissues are fully immersed in the fixative, preventing them from floating around, and facilitates observation during the sampling process with minimal damage to the small tissues. However, in actual use, the following drawbacks have been found:

[0004] (1) If the specimen bottle is tilted or inverted during transport or storage, the fixative will flow with it, but the specimen box is restricted by the limiting basket and connecting rod in the limiting cavity at the bottom of the specimen bottle, and the tissue may detach from the fixative.

[0005] (2) Low level of cooperation from clinicians: When using this method, clinicians need to open the specimen bottle cap first, take out the specimen box through the connecting rod, open the specimen box, put the small tissue into the specimen box, close the specimen box cap, and put the specimen box into the specimen bottle through the connecting rod. When placing the specimen box, the specimen box must be accurately placed into the limiting basket at the bottom of the specimen bottle. Compared with the traditional method of "directly putting the small tissue into a simple capped bottle containing formalin fixative", the operation steps are complicated and the operation is more difficult.

[0006] (3) When pathologists collect specimens, they take out the specimen box through the connecting rod, and then unscrew the specimen box from the connecting rod and place it in the embedding box, which is a rather cumbersome operation;

[0007] (4) Poor water permeability: The specimen box lid is made of plastic and is not permeable to water. There are small gaps around it. In daily practice, it has been found that the specimen box has poor water permeability, and the specimen cannot be properly fixed and dehydrated, which affects the pathological diagnosis and creates a new pain point in the industry. Utility Model Content

[0008] The main purpose of this invention is to provide a novel device for storing small tissues, which solves the problems existing in the prior art, so that small tissues can always be fixed in formalin fixative, making it easier to pick up and put down and improving water permeability.

[0009] To achieve the above objectives, the solution of this utility model is:

[0010] A novel device for storing small tissues includes a specimen bottle and a specimen box. The specimen bottle includes a bottle body and a cap that can be opened and closed. The specimen box includes a box body and a box cap that can be opened and closed. The box body includes five surfaces: front, back, left, right, and bottom. The box cap is the top surface of the specimen box. The left, right, and front surfaces of the box body are provided with a mesh structure. The bottom surface of the box body and the middle of the box cap are both hollowed out and connected with embedding paper. A counterweight is embedded in the rear of the box body.

[0011] The bottle cap is threaded to the upper opening of the bottle body.

[0012] The specimen box and its lid are both made of plastic.

[0013] The counterweight is made of metal.

[0014] The rear end of the lid is pivotally connected to the upper rear edge of the box body, and its front end is snapped to the upper front edge of the box body.

[0015] Preferably, the lower front surface of the box body is provided with a snap fastener, and the upper front edge of the box body is provided with a snap groove for the snap fastener to move and cooperate.

[0016] After adopting the above technical solution, the present invention has the following technical effects:

[0017] This invention employs a specimen box to store small tissues. A counterweight at the back of the box allows gravity to keep it submerged in the fixative solution in the specimen bottle. Regardless of the bottle's orientation (vertical, angled, or inverted), the specimen box remains submerged in the fixative, ensuring the tissue sample is completely immersed. Furthermore, the grid structure on the left, right, and front of the box, along with the embedding paper on the bottom and lid, allows for smooth flow of fixative and other liquids. The use of embedding paper commonly used in pathology for embedding small tissues significantly improves the box's permeability, addressing a common industry pain point of poor permeability. The specimen box design makes inserting and removing small tissues more convenient, faster, and safer. It can also be placed in a standard pathology embedding box, reducing the number of times small tissues need to be handled and minimizing pressure and damage. Attached Figure Description

[0018] Figure 1 This is a structural schematic diagram of a specific embodiment of the present utility model.

[0019] Figure 2 This is a perspective view of the specimen box in the closed state according to a specific embodiment of the present invention.

[0020] Figure 3 This is a perspective view of the specimen box in the open state according to a specific embodiment of the present invention.

[0021] Explanation of icon numbers:

[0022] 1-Specimen bottle; 11-Bottle body; 12-Bottle cap;

[0023] 2-Specimen box; 21-Box body; 211-Grid structure; 212-Snap groove; 22-Box lid; 23, 23'-Embedding paper; 24-Counterweight;

[0024] 3- Snap fastener. Detailed Implementation

[0025] To further explain the technical solution of this utility model, the following detailed description is provided through specific embodiments.

[0026] refer to Figures 1 to 3 As shown, this utility model discloses a novel small tissue storage device, including a specimen bottle 1 and a specimen box 2;

[0027] The specimen bottle 1 includes an openable and closable bottle body 11 and a bottle cap 12, which can be used to hold fixatives such as formalin;

[0028] Specimen box 2 includes an openable and closable box body 21 and a box lid 22, see [link / reference] Figure 2As shown in the diagram, the box body 21 includes five sides: front, back, left, right, and bottom of the specimen box 2, and the lid 22 is the top surface of the specimen box 2; the left, right, and front sides of the box body 21 are all provided with a grid structure 211; the bottom surface of the box body 21 and the middle of the lid 22 are both hollowed out and connected with embedding paper 23, 23'; a counterweight 24 is embedded in the back of the box body 21.

[0029] Through the above scheme, this utility model uses a specimen box 2 to store small tissues. Because a counterweight 24 is provided at the rear of the specimen box 2, gravity allows the specimen box 2 to sink to the bottom of the fixative in the specimen bottle 1. Furthermore, regardless of how the specimen bottle 1 is placed (vertically, obliquely, or horizontally upside down), the specimen box 2 remains submerged in the fixative, ensuring that the sample tissue is completely immersed. Simultaneously, the mesh structures 211 on the left, right, and front of the box body 21, along with the embedding paper 23 on the bottom of the box body 21 and the embedding paper 23' on the lid 22, allow for smooth flow of fixative and other liquids into and out of the specimen. This specimen box 2, in particular, uses embedding paper commonly used in pathology departments for embedding small tissues, which improves the water permeability of the specimen box, thus solving the industry pain point of poor water permeability of specimen box 2. The design of specimen box 2 makes it more convenient, faster and safer to put in and take out small tissues, and can be placed together with small tissues into the common embedding box used in pathology departments, reducing the number of times small tissues are handled, thereby reducing the compression and damage to small tissues. Compared with the previous design, the design of this utility model that removes the connecting rod and the limiting basket makes it easier for clinicians to put small tissues into the specimen box and to take out the specimen box.

[0030] The following are specific embodiments of the present invention.

[0031] The cap 12 is threaded to the upper opening of the bottle body 11, which facilitates the disassembly and assembly of the cap 12 and enables a stable seal by utilizing the threaded structure to prevent the fixative from leaking out when the specimen bottle 1 is tilted.

[0032] The body 21 and lid 22 of the specimen box 2 mentioned above are both made of plastic.

[0033] The aforementioned counterweight 24 is made of metal and is embedded in the back of the box 21, without contacting the fixative or sample tissue.

[0034] The rear end of the lid 22 is pivotally connected to the upper rear edge of the box body 21, and its front end is snap-fitted to the upper front edge of the box body 21. This allows for a flip-top fit between the lid 22 and the box body 21, and their relative fixation is achieved through a snap-fit ​​connection.

[0035] Furthermore, a snap button 3 is provided on the lower front surface of the aforementioned box 22, and a snap groove 212 is provided on the upper front edge of the box 21 for the snap button 3 to move and cooperate.

[0036] In this embodiment, the specimen bottle 1 has a height of 40mm and a diameter of 25mm; the specimen box 2 (including the lid 21) has a length of 20mm, a width of 15mm, and a height of 5mm.

[0037] The implementation steps of this utility model are as follows:

[0038] The clinician places the small tissue into specimen box 2, closes the lid 22, places specimen box 2 into specimen bottle 1, adds an appropriate amount of formalin solution to specimen bottle 1, tightens the cap 12, and affixes a label. After being sent to the pathology department, the pathologist unscrews the cap 12, uses forceps to remove specimen box 2, opens the lid 22 to examine the small tissue, closes the lid 22, and places specimen box 2 into a pathology department-standard embedding cassette for subsequent processing such as fixation, dehydration, clearing, and paraffin infiltration.

[0039] The above embodiments and figures are not intended to limit the product form and style of this utility model. Any appropriate changes or modifications made by those skilled in the art should be considered as not departing from the patent scope of this utility model.

Claims

1. A novel device for storing small tissues, characterized in that: Includes specimen bottles and specimen boxes; The specimen bottle includes an openable and closable bottle body and a bottle cap; The specimen box includes a box body and a lid that can be opened and closed. The box body includes five sides: front, back, left, right, and bottom. The lid is the top surface of the specimen box. The left, right, and front sides of the box body are provided with a grid structure. The bottom surface of the box body and the middle of the lid are both hollowed out and connected with embedding paper. A counterweight is embedded in the back of the box body.

2. The novel small tissue storage device as described in claim 1, characterized in that: The bottle cap is threaded to the upper opening of the bottle body.

3. The novel small tissue storage device as described in claim 1, characterized in that: The specimen box and its lid are both made of plastic.

4. The novel small tissue storage device as described in claim 1, characterized in that: The counterweight is made of metal.

5. The novel small tissue storage device as described in claim 1, characterized in that: The rear end of the lid is pivotally connected to the upper rear edge of the box body, and its front end is snapped to the upper front edge of the box body.

6. The novel small tissue storage device as described in claim 5, characterized in that: The lower front surface of the box is provided with a snap fastener, and the upper front edge of the box is provided with a snap groove for the snap fastener to move and engage.