Biopsy processing reagent bottle

Abstract

The application relates to a biopsy processing reagent bottle which comprises a wave structure, a puncture needle, an upper cavity, a second sealing structure and a lower cavity; the upper cavity is in sealing connection with the lower cavity; the upper cavity is provided with the second sealing structure at the lower part and the wave structure at the upper part; the wave structure is a compressible structure; one end of the puncture needle is connected to the wave structure, the wave structure is compressed, and the puncture needle can be driven to move in the same direction; the puncture needle can pierce the second sealing structure, so that the upper cavity and the lower cavity are communicated at the piercing position. The wave structure is compressed to drive the puncture needle to pierce the second sealing structure, so that the liquid in the upper cavity flows into the lower cavity, the biopsy tissue at the bottom of the lower cavity is soaked, and the whole process is convenient and rapid.

Description

Technical Field

[0001] This application relates to the field of biopsy processing technology, and in particular to a biopsy processing reagent bottle. Background Technology

[0002] Biopsy is one of the key methods for diagnosing pathological conditions. Tissue samples collected during a biopsy need to be preserved in specific reagents to ensure sample quality, which is usually done in biopsy reagent vials.

[0003] Some existing biopsy reagent bottles employ complex manufacturing processes and material selections, which not only increases production costs but also results in higher prices for the final product, placing a significant economic burden on medical institutions. The high cost limits the application of these high-quality but expensive reagent bottles in primary healthcare units, impacting their widespread adoption.

[0004] Furthermore, some biopsy reagent bottles are designed with too many components or special structures to achieve specific functions (such as leak prevention, sealing, and label fixation). This not only increases the difficulty of the manufacturing process but also makes them susceptible to damage from impacts during transportation and storage. Complex structures may also lead to low assembly efficiency and increased labor costs.

[0005] Some biopsy reagent bottles currently on the market do not fully consider the actual needs of users. For example, the opening and closing operations are not simple enough, or they lack intuitive design elements to help medical staff quickly identify and operate them correctly. In addition, the size and shape of some reagent bottles are not suitable for one-handed operation, especially when wearing protective equipment, which further reduces the convenience of use. Utility Model Content

[0006] Based on this, this application provides a biopsy processing reagent bottle, which, through its simple design, enables the safe placement and preservation of samples and improves the efficiency of biopsy processing.

[0007] To address the aforementioned problems, this utility model provides a biopsy treatment reagent bottle, comprising: a wave structure, a needle, an upper cavity, a second sealing structure, and a lower cavity;

[0008] The upper cavity and the lower cavity are sealed together.

[0009] The lower part of the upper cavity is provided with a second sealing structure, and the upper part is provided with a wave structure;

[0010] The wave structure is a compressible structure;

[0011] One end of the needle is connected to the wave structure. Compressing the wave structure can drive the needle to move in the same direction.

[0012] The needle can pierce the second sealing structure, making the upper cavity and the lower cavity communicate at the puncture point.

[0013] Furthermore, the wave structure has inelastic recovery characteristics, allowing the liquid in the upper cavity to be drained into the lower cavity through the needle;

[0014] The wave structure has elastic recovery properties. After the second sealing structure is pierced by the needle, a puncture hole is formed, and the liquid in the upper cavity flows into the lower cavity through the puncture hole.

[0015] Furthermore, the lower edge of the wave structure is connected to the inner wall of the upper part of the upper cavity, thereby sealing the upper part of the upper cavity.

[0016] Furthermore, the wave structure has a blind hole in the middle, and one end of the needle is embedded in the blind hole; or, one end of the needle is connected to the bottom of the wave structure.

[0017] Furthermore, the needle includes a tip section and a body section, the tip section being used to pierce the second sealing structure; the body section has a polygonal cross-section or a groove is formed on the surface of the body section.

[0018] Furthermore, the groove on the surface of the needle body segment surrounds the surface of the needle body segment and forms an angle of less than 90° with the axis of the needle body segment, or the groove on the surface of the needle body segment is parallel to the axis of the needle body segment.

[0019] Furthermore, it also includes a top cover, which is connected to the outer wall of the upper end of the upper cavity and can cover the wave structure.

[0020] Furthermore, the upper cover covering the wave structure is connected to the outer wall of the upper cavity by means of a tear-off ring, screw, or snap-fit.

[0021] Furthermore, it also includes a first sealing structure to achieve a seal at the connection between the upper cavity and the lower cavity.

[0022] Furthermore, after the wave structure is compressed to its maximum stroke, the needle segment can enter the space of the lower cavity.

[0023] Compared with the prior art, the present invention has the following beneficial effects:

[0024] This invention utilizes a squeezing wave structure to drive the needle to pierce the second sealing structure, allowing the liquid in the upper cavity to flow into the lower cavity, thus immersing the biopsy tissue at the bottom of the lower cavity. The entire process is convenient and rapid, and can be used anytime and anywhere, saving valuable time for biopsy tissue testing. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of an embodiment of the present utility model;

[0026] Figure 2This is a schematic diagram showing the state of the present invention before use.

[0027] Figure 3 This is a schematic diagram of opening the lower cavity in an embodiment of the present invention;

[0028] Figure 4 This is a schematic diagram of opening the top cover in an embodiment of this utility model.

[0029] Among them: 1-top cover, 2-wave structure, 3-needle, 4-upper cavity, 5-sealing structure, 6-lower cavity, 7-sealing ring. Detailed Implementation

[0030] The present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the scope of the present application.

[0031] This application provides a biopsy treatment reagent bottle, such as... Figure 1 As shown, it includes: wave structure 2, needle 3, upper cavity 4, second sealing structure 7 and lower cavity 6;

[0032] The upper cavity 4 and the lower cavity 6 are sealed together. The upper cavity 4 is used to hold a liquid, such as formalin solution, for soaking the biopsy tissue; the lower cavity 6 is used to hold the tissue to be biopsied. The seal here includes sealing the upper cavity 4 and the lower cavity 6 at the connection, and in the initial stage, the seal achieves spatial isolation between the two cavities.

[0033] The upper cavity 4 has a second sealing structure 7 at its lower part and a wave structure 2 at its upper part. Specifically, the second sealing structure 7 achieves spatial isolation between the upper cavity 4 and the lower cavity 6 in the initial stage; the wave structure 2 achieves sealing isolation between the upper cavity 4 and the outside world.

[0034] The second sealing structure 7 is a sealing membrane structure that acts as a barrier between the upper cavity 4 and the lower cavity 6, ensuring complete isolation between the two cavities in the inactive state and preventing the mixing of internal liquids or gases. The second sealing structure 7 needs to have appropriate thickness and material to ensure that the needle 3 can easily penetrate while maintaining sufficient strength to prevent accidental breakage. In specific designs, plastic films such as polyethylene (PE) and polypropylene (PP) are preferred, as these materials have good flexibility and chemical stability, making them suitable for use in medical environments. They provide sufficient strength to maintain a seal while also being thin enough to allow the needle 3 to penetrate easily. Aluminum foil composite films can also be used, which not only provide strong barrier performance but also effectively block the effects of light, moisture, and other environmental factors.

[0035] The thickness of the aforementioned second sealing structure 7 needs to be precisely designed to ensure sufficient strength to prevent accidental breakage while also ensuring that the needle 3 can penetrate smoothly. Typically, the thickness ranges from 0.05 mm to 0.2 mm, depending on the material used and its properties.

[0036] The wave structure 2 is a compressible structure to save space. One end of the needle 3 is connected to the wave structure 2. Compressing the wave structure 2 can drive the needle 3 to move in the same direction. The needle 3 can pierce the second sealing structure 7 to establish a connection between the upper cavity 4 and the lower cavity 6.

[0037] Based on the above structure, by squeezing the wave structure 2, the needle 3 can be driven to pierce the second sealing structure 7, so that the liquid in the upper cavity 4 flows into the lower cavity 6, thereby immersing the biopsy tissue at the bottom of the lower cavity 6.

[0038] like Figure 1 As shown, in one embodiment, the wave structure 2 is designed to have non-elastic recovery characteristics. Pressing the wave structure 2 causes the needle 3 to penetrate the second sealing structure 7. After pressing, the wave structure 2 no longer returns to its original state, that is, it basically retains the position after pressing. The needle stays in the second sealing structure 7, and the liquid in the upper cavity 4 is drained into the lower cavity 6 through the needle 3.

[0039] In another embodiment, the wave structure 2 is designed to have elastic recovery characteristics. Pressing the wave structure 2 causes the needle 3 to pierce the second sealing structure 7. After pressing, the needle 3 is pulled out from the second sealing structure 7. The second sealing structure 7 is pierced by the needle 3 to form a piercing hole. The wave structure 2 returns to its original state, and the liquid in the upper cavity 4 flows into the lower cavity 6 through the piercing hole.

[0040] In one implementation, the lower edge of the wave structure 2 is connected to the inner wall of the upper part of the upper cavity 4, thereby sealing the upper part of the upper cavity 4. The wave structure 2 is acted upon from top to bottom, causing it to deform under downward pressure and resulting in downward displacement.

[0041] As another implementation, the wave structure 2 can be designed to move downward as a whole and form a sliding seal with the inner wall of the upper cavity 4. The downward movement of the wave structure 2 drives the needle 3 to move downward. The needle 3 stays in the second sealing structure 7 and guides the liquid in the upper cavity 4 to the lower cavity 6 through the needle 3.

[0042] For example, a blind hole can be made in the middle of the wave structure 2, one end of the needle 3 can be inserted into the blind hole and fixed in place, such as... Figure 1As shown; or a through hole is made in the middle of the wave structure 2, and a thin plate is set on the top of the wave structure 2. After the needle 3 passes through the through hole, it is fixed on the thin plate; or, no hole is made in the middle of the wave structure 2, and one end of the needle 3 is directly connected to the bottom of the wave structure 2.

[0043] Based on the above embodiments, the needle 3 is designed to include a needle tip segment and a needle body segment. The needle tip segment is used to pierce the second sealing structure 7. The end of the needle 3 can be designed as a flat or multi-edged structure, which can form a large opening when piercing the second sealing structure 7, facilitating the rapid flow of liquid into the lower cavity 6. The needle body segment has a cylindrical or polygonal cross-section or has grooves on its surface. The needle tip segment is specifically used to pierce the second sealing structure 7. The needle tip segment should have sufficient sharpness and strength to ensure that it can easily penetrate the second sealing structure 7 without bending or breaking. It can be made of stainless steel or other high-strength alloy materials and is precision machined into a slender and sharp shape to minimize the force required for piercing.

[0044] Specifically, when the wave structure 2 is an elastically compressible and recoverable structure, the cross-sectional shape of the needle 3 can be selected as cylindrical, polygonal, or have grooves formed on the surface of the needle body, as long as it can pierce the second sealing structure 7. When the wave structure 2 is a non-compressible structure or a structure that moves downward as a whole, the cross-sectional shape of the needle 3 can be selected as polygonal (such as triangular, square, etc.) or have grooves formed on the surface of the needle body, to facilitate drainage and exhaust. Preferably, the grooves on the surface of the needle body surround the surface of the needle body and form an angle of less than 90° with the axis of the needle body, or the grooves on the surface of the needle body are parallel to the axis of the needle body, serving as drainage and exhaust channels, which helps maintain the pressure balance between the upper cavity 4 and the lower cavity 6.

[0045] As one embodiment, it also includes a top cover 1, which is connected to the outer wall of the upper end of the upper cavity 4 and can cover the wave structure 2. It is connected to the outer wall of the upper cavity 4 by tearing ring or screwing or snapping. The addition of the top cover 1 is an additional safety and protection measure, which can effectively prevent the wave structure 2 from being accidentally crushed during transportation or storage.

[0046] The above connection utilizes a disposable tear-off ring design, allowing users to easily remove the top cover 1 by simply pulling the tear strip. This method is simple and intuitive, suitable for single-use applications, and provides clear opening indicators to prevent reuse. The top cover 1 can be secured to the outer wall of the upper cavity 4 via a screw thread. This design allows users to open and close the top cover 1 multiple times, suitable for applications requiring repeated operation. Furthermore, the screw thread provides excellent sealing, further protecting internal components from external environmental influences. Quick installation and removal are achieved using elastic clips or similar mechanisms, facilitating rapid opening and closing, particularly suitable for the need to quickly prepare reagent bottles in emergency situations.

[0047] As one embodiment, it also includes a first sealing structure 5, which is used to seal the connection between the upper cavity 4 and the lower cavity 6. The sealing can be achieved by means of sealing rings or thread tightening, to ensure a complete seal between the upper cavity 4 and the lower cavity 6, prevent any liquid leakage, and ensure the stability of the internal environment and the quality of the sample.

[0048] For sealing methods using sealing rings, O-rings can be selected and installed at the connection between the upper cavity 4 and the lower cavity 6, achieving a seal through compression deformation. Alternatively, lip seals with unidirectional or bidirectional lip designs can be selected, providing excellent sealing performance under low to medium pressure conditions and automatically adjusting to accommodate slight surface unevenness.

[0049] In threaded sealing systems, the connection between the upper cavity 4 and the lower cavity 6 can be designed as a threaded interface, achieving a seal through tightening. This method not only provides a reliable mechanical connection but also allows users to open and close the device multiple times without affecting the sealing effect. Alternatively, a sealing gasket, such as a flat sealing gasket or a multi-layer composite gasket, can be added at the connection point to further enhance the sealing performance.

[0050] In this embodiment, after the wave structure 2 is compressed to its maximum stroke, the needle segment can enter the space of the lower cavity 6, ensuring that the second sealing structure 7 is fully punctured, forming a larger opening to facilitate the flow of liquid.

[0051] In this embodiment, the volume of the upper cavity 4 is not less than 1 / 4 of the volume of the lower cavity 6. This ratio ensures that when the wave structure 2 is compressed to its maximum stroke, the amount of liquid flowing into the upper cavity 4 is sufficient to completely submerge the biopsy tissue located at the bottom of the lower cavity 6. The minimum required liquid volume can be calculated based on the size of the lower cavity 6 and the expected size of the biopsy tissue to be stored, thereby determining the minimum volume of the upper cavity 4.

[0052] In a preferred embodiment of this application, a slightly inclined liquid collection tank can be designed at the bottom of the lower cavity 6, allowing the liquid to be evenly distributed and concentrated around the biopsy tissue, thus improving the soaking effect. And / or a support structure or partition can be provided inside the lower cavity 6 to prevent the biopsy tissue from floating or shifting, ensuring that it remains in a liquid environment at all times.

[0053] like Figure 2-4 As shown, in one embodiment of the usage process, in the initial state (i.e., the unused state), a certain amount of reagent is pre-filled in the upper cavity 4 to ensure sufficient liquid volume, and it is isolated from the outside world by the upper cover 1. Activation process: When the user removes the lower cavity 6, inserts the biopsy tissue, and installs the lower cavity 6, the upper cover 1 is removed, the wave structure 2 is compressed, and the needle 3 penetrates the second sealing structure 7, allowing the reagent in the upper cavity 4 to quickly flow into the lower cavity 6, contacting the biopsy tissue in the lower cavity 6 until the biopsy tissue is submerged.

[0054] It should be noted that, in this document, the term "comprising" or any other variation thereof is intended to cover non-exclusive inclusion, such that an article or device that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such an article or device. Without further limitation, an element defined by the phrase "comprising..." does not exclude the presence of other identical elements in the article or device that includes said element.

[0055] The terms “upper part,” “upper end,” and “bottom” refer to the reference directions for “upper” and “lower” when the upper cavity of the biopsy reagent bottle in this application is placed with the upper cavity above and the lower cavity below.

[0056] The specific embodiments described above do not constitute a limitation on the scope of protection of this application. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the scope of protection of this application.

Claims

1. A biopsy treatment reagent bottle, characterized in that, include: Wave structure (2), needle (3), upper cavity (4), second sealing structure (7) and lower cavity (6); The upper cavity (4) and the lower cavity (6) are sealed together; The lower part of the upper cavity (4) is provided with a second sealing structure (7), and the upper part is provided with a wave structure (2); The wave structure (2) is a compressible structure; One end of the needle (3) is connected to the wave structure (2). Compressing the wave structure (2) can drive the needle (3) to move in the same direction. The needle (3) can pierce the second sealing structure (7), so that the upper cavity (4) and the lower cavity (6) are connected at the piercing point.

2. The biopsy treatment reagent bottle as described in claim 1, characterized in that, The wave structure (2) has non-elastic recovery characteristics, and the liquid in the upper cavity (4) is drained into the lower cavity (6) through the needle (3); The wave structure (2) has elastic recovery characteristics. After the second sealing structure (7) is pierced by the needle (3), a puncture hole is formed. The liquid in the upper cavity (4) flows into the lower cavity (6) through the puncture hole.

3. The biopsy treatment reagent bottle as described in claim 1, characterized in that, The lower edge of the wave structure (2) is connected to the inner wall of the upper part of the upper cavity (4), thereby sealing the upper part of the upper cavity (4).

4. The biopsy treatment reagent bottle as described in claim 1, characterized in that, The wave structure (2) has a blind hole in the middle, and one end of the needle (3) is embedded in the blind hole and fixed; or, one end of the needle (3) is connected to the bottom of the wave structure (2).

5. The biopsy treatment reagent bottle as described in claim 1, characterized in that, The needle (3) includes a needle tip section and a needle body section. The needle tip section is used to pierce the second sealing structure (7). The cross-section of the needle body section is cylindrical or polygonal, or a groove is provided on the surface of the needle body section.

6. The biopsy treatment reagent bottle as described in claim 5, characterized in that, The groove on the surface of the needle body section surrounds the surface of the needle body section and forms an angle of less than 90° with the axis of the needle body section, or the groove on the surface of the needle body section is parallel to the axis of the needle body section.

7. The biopsy treatment reagent bottle as described in claim 1, characterized in that, It also includes a top cover (1), which is connected to the outer wall of the upper end of the upper cavity (4) and can cover the wave structure (2).

8. The biopsy treatment reagent bottle as described in claim 7, characterized in that, The upper cover (1) covering the wave structure (2) is connected to the outer wall of the upper cavity (4) by tearing rings or by screwing or snapping.

9. The biopsy treatment reagent bottle as described in claim 1, characterized in that, It also includes a first sealing structure (5) to achieve a seal at the connection between the upper cavity (4) and the lower cavity (6).

10. The biopsy treatment reagent bottle as described in claim 5, characterized in that, After the wave structure (2) is compressed to its maximum stroke, the needle segment can enter the space of the lower cavity (6).

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