Pharmaceutical device with PFA inner liner

Abstract

The utility model discloses a kind of lining PFA high-cleanliness pharmaceutical devices, including pulverization jar, PFA lining layer is arranged on the inner wall of the pulverization jar, air pump is fixed in the top side of the pulverization jar, air pipe is connected on the output port of the air pump, the air pipe one end is provided with air guide ring. Advantageous effect lies in: the utility model is provided with PFA lining layer on the inner wall of pulverization jar and high-pressure cleaning mechanism consisting of air pump, air pipe, air guide ring and nozzle, in the process of using device, the characteristics (corrosion resistance, low friction coefficient) of PFA lining layer itself can be used to prevent drug residues, while cooperating with air pump to generate high-pressure gas through air pipe, air guide ring and nozzle spray effect on pulverization mechanism, the drug remaining on the surface of pulverization mechanism can be cleaned, the combination of both can ensure that drug is discharged comprehensively, on the one hand, ensure the recovery rate of drug, on the other hand, avoid the impact on subsequent drug pulverization, with higher use performance.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical equipment technology, specifically to a high-cleanliness pharmaceutical equipment lined with PFA. Background Technology

[0002] Pharmaceutical manufacturing is the production sector of chemical drugs, consisting of two parts: the production of active pharmaceutical ingredients (APIs) and the production of pharmaceutical formulations. APIs are the material basis for drug production, but they must be processed into pharmaceutical formulations suitable for oral administration to become drugs.

[0003] Existing pharmaceutical equipment often uses stainless steel tanks to pulverize pharmaceutical raw materials during use. However, during the discharge process, some drug residues inevitably remain on the inner wall of the pulverizing tank and on the pulverizing mechanism. These residues are difficult to clean and can easily mix with the drugs being pulverized later, affecting their performance and resulting in lower efficiency. Therefore, there is an urgent need for a PFA-lined high-cleanliness pharmaceutical equipment to solve these problems. Utility Model Content

[0004] (a) Technical problems to be solved

[0005] The technical problem to be solved by this utility model is to provide a high-cleanliness pharmaceutical device lined with PFA, based on the current state of the technology.

[0006] (II) Technical Solution

[0007] This utility model is achieved through the following technical solution: This utility model proposes a high-cleanliness pharmaceutical device lined with PFA, including a pulverizing tank, on which a PFA liner is provided on the inner wall. An air pump is fixed on one side of the top of the pulverizing tank, and an air pipe is connected to the output port of the air pump. An air guide ring is provided at one end of the air pipe, and multiple sets of nozzles are circumferentially distributed on the bottom wall of the air guide ring. A pulverizing motor is provided on one side of the air pump, and a drive shaft is connected to the output shaft of the pulverizing motor. Multiple sets of pulverizing blades are circumferentially distributed on the outer wall of the drive shaft.

[0008] Furthermore, the PFA liner is bonded to the inner wall of the grinding tank, and the air pump is fixed to the top of the grinding tank by bolts.

[0009] Furthermore, a filter is installed on the air inlet port of the air pump, and the air pipe is fixed between the output port of the air pump and the air guide ring.

[0010] Furthermore, the air guide ring is fixed to the inner wall of the top of the pulverizing tank by a pipe clamp, and the nozzle is threaded onto the bottom wall of the air guide ring.

[0011] Furthermore, the output shaft of the pulverizing motor is fixedly connected to the drive shaft, and the pulverizing blade is fixed to the drive shaft by screws.

[0012] Furthermore, a feeding hopper is reserved on one side of the top of the crushing tank, and a support frame is fixed around the bottom of the crushing tank.

[0013] Furthermore, a discharge pipe is provided in the middle of the bottom of the crushing tank, and a solenoid valve is installed on the discharge pipe.

[0014] (III) Beneficial Effects

[0015] Compared with the prior art, this utility model has the following advantages:

[0016] This invention features a PFA liner on the inner wall of the grinding tank and a high-pressure cleaning mechanism consisting of an air pump, air pipe, air guide ring, and nozzle. During use, the PFA liner's inherent properties (corrosion resistance and low coefficient of friction) prevent drug residue. Simultaneously, the air pump generates high-pressure gas that is sprayed onto the grinding mechanism through the air pipe, air guide ring, and nozzle, cleaning any residual drug from the grinding mechanism's surface. This combination ensures complete drug discharge, guaranteeing drug recovery and preventing any impact on subsequent drug grinding, resulting in high performance. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of a PFA-lined high-cleanliness pharmaceutical device according to the present invention;

[0018] Figure 2 This is a schematic diagram of the internal structure of the pulverizing tank in a PFA-lined high-cleanliness pharmaceutical device according to the present invention;

[0019] Figure 3 This is a schematic diagram of the connection relationship between the gas pipe and the gas guide ring in a PFA-lined high-cleanliness pharmaceutical device according to this utility model.

[0020] The annotations in the attached figures are explained as follows:

[0021] 1. Grinding tank; 2. Support frame; 3. Feeding hopper; 4. Air pipe; 5. Air pump; 6. Grinding motor; 7. Discharge pipe; 8. Solenoid valve; 9. Drive shaft; 10. Grinding blade; 11. PFA inner liner; 12. Air guide ring; 13. Nozzle. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0023] like Figures 1-3 As shown, a high-cleanliness pharmaceutical device with PFA lining in this embodiment includes a pulverizing tank 1. A PFA lining layer 11 is provided on the inner wall of the pulverizing tank 1 to prevent drugs from adhering to the inner wall of the pulverizing tank 1. An air pump 5 is fixed on one side of the top of the pulverizing tank 1. An air pipe 4 is connected to the output port of the air pump 5. An air guide ring 12 is provided at one end of the air pipe 4. Multiple sets of nozzles 13 are distributed in a circular pattern on the bottom wall of the air guide ring 12 to clean the drugs remaining on the surface of the pulverizing mechanism. A pulverizing motor 6 is provided on one side of the air pump 5. A drive shaft 9 is connected to the output shaft of the pulverizing motor 6. Multiple sets of pulverizing blades 10 are distributed in a circular pattern on the outer wall of the drive shaft 9 to pulverize the drug raw materials.

[0024] like Figures 1-3 In this embodiment, the PFA liner 11 is bonded to the inner wall of the grinding tank 1. The air pump 5 is fixed to the top of the grinding tank 1 by bolts. A filter is installed on the air inlet port of the air pump 5. The air pipe 4 is fixed between the output port of the air pump 5 and the air guide ring 12. The air guide ring 12 is fixed to the inner wall of the top of the grinding tank 1 by a pipe clamp. The nozzle 13 is threaded onto the bottom wall of the air guide ring 12. During the use of the device, the PFA liner 11 can be used to prevent drug residue by utilizing its own characteristics of corrosion resistance and low friction coefficient. At the same time, the high-pressure gas generated by the air pump 5 is sprayed onto the grinding mechanism through the air pipe 4, the air guide ring 12 and the nozzle 13, which can clean the drug residue on the surface of the grinding mechanism. The combination of the two can ensure that the drug is completely discharged, on the one hand ensuring the drug recovery rate, and on the other hand avoiding the impact on the subsequent drug grinding, thus having high performance.

[0025] like Figures 1-3 In this embodiment, the output shaft of the pulverizing motor 6 is fixedly connected to the transmission shaft 9, and the pulverizing blade 10 is fixed to the transmission shaft 9 by screws. A feeding hopper 3 is reserved on one side of the top of the pulverizing tank 1, and a support frame 2 is fixed around the bottom of the pulverizing tank 1. A discharge pipe 7 is reserved in the middle of the bottom of the pulverizing tank 1, and a solenoid valve 8 is installed on the discharge pipe 7. During the use of the device, the drug raw materials are injected into the pulverizing tank 1 through the feeding hopper 3. The pulverizing motor 6 drives the pulverizing blade 10 to rotate at high speed through the transmission shaft 9 to pulverize the raw materials. The pulverized raw materials are discharged through the discharge pipe 7 for collection and subsequent pressing. The solenoid valve 8 controls the opening and closing of the discharge pipe 7.

[0026] The specific implementation process of this embodiment is as follows: First, the device is placed in place and connected to an external power source. During the use of the device, the drug raw materials are injected into the pulverizing tank 1 through the feeding hopper 3. The pulverizing motor 6 drives the pulverizing blade 10 to rotate at high speed through the transmission shaft 9 to pulverize the raw materials. The pulverized raw materials are discharged through the discharge pipe 7 for collection and subsequent pressing. During the discharge process, the PFA inner lining layer 11 can be used to prevent drug residue by utilizing its own characteristics of corrosion resistance and low friction coefficient. At the same time, the air pump 5 generates high-pressure gas, which is sprayed onto the pulverizing mechanism through the air pipe 4, the air guide ring 12 and the nozzle 13 to clean the drug residue on the surface of the pulverizing mechanism. The combination of the two can ensure that the drug is completely discharged, on the one hand ensuring the drug recovery rate, and on the other hand avoiding the impact on the subsequent pulverization of drugs, thus having high performance.

[0027] The above description of the disclosed embodiments enables those skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A high-cleanliness pharmaceutical manufacturing device lined with PFA, characterized in that: The device includes a pulverizing tank (1), with a PFA inner lining (11) on the inner wall of the pulverizing tank (1). An air pump (5) is fixed on one side of the top of the pulverizing tank (1). An air pipe (4) is connected to the output port of the air pump (5). An air guide ring (12) is provided at one end of the air pipe (4). Multiple sets of nozzles (13) are distributed in a circular pattern on the bottom wall of the air guide ring (12). A pulverizing motor (6) is provided on one side of the air pump (5). A drive shaft (9) is connected to the output shaft of the pulverizing motor (6). Multiple sets of pulverizing blades (10) are distributed in a circular pattern on the outer wall of the drive shaft (9).

2. The PFA-lined high-cleanliness pharmaceutical manufacturing device according to claim 1, characterized in that: The PFA liner (11) is bonded to the inner wall of the pulverizing tank (1), and the air pump (5) is fixed to the top of the pulverizing tank (1) by bolts.

3. The PFA-lined high-cleanliness pharmaceutical manufacturing device according to claim 1, characterized in that: A filter is installed on the air inlet port of the air pump (5), and the air pipe (4) is fixed between the output port of the air pump (5) and the air guide ring (12).

4. The PFA-lined high-cleanliness pharmaceutical manufacturing device according to claim 1, characterized in that: The air guide ring (12) is fixed to the inner wall of the top of the crushing tank (1) by a pipe clamp, and the nozzle (13) is installed on the bottom wall of the air guide ring (12) by a thread.

5. A high-cleanliness pharmaceutical manufacturing device lined with PFA according to claim 4, characterized in that: The output shaft of the crushing motor (6) is fixedly connected to the transmission shaft (9), and the crushing blade (10) is fixed on the transmission shaft (9) by screws.

6. A high-cleanliness pharmaceutical manufacturing apparatus lined with PFA according to claim 5, characterized in that: A feeding hopper (3) is reserved on one side of the top of the crushing tank (1), and a support frame (2) is fixed around the bottom of the crushing tank (1).

7. A high-cleanliness pharmaceutical manufacturing apparatus lined with PFA according to claim 6, characterized in that: The bottom of the crushing tank (1) has a pre-reserved discharge pipe (7), and a solenoid valve (8) is installed on the discharge pipe (7).

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