Supine restraint device used for experiments on monkey eyes

Abstract

This utility model relates to the field of restraint technology for laboratory monkeys, specifically to a supine restraint device for eye experiments on laboratory monkeys. The device includes: a support plate with a groove, and a rotating seat extending along the groove; a head support component connected to the rotating seat and tiltable at a predetermined angle relative to the rotating seat; and a back support component connected to the groove and movable relative to the support plate along the length of the groove to a predetermined position. This restraint device supports the laboratory monkey in a supine position through three support points: head, back, and buttocks. This ensures the monkey is in a neutral position, preventing lateral tilting and facilitating intraocular injection, while minimizing restraint. This allows for observation of conditioned reflexes in monkeys under deep anesthesia and prevents accidental death.

Description

Technical Field

[0001] This utility model relates to the field of restraint technology for experimental monkeys, and more specifically to a supine restraint device for eye experiments on experimental monkeys. Background Technology

[0002] The restraint requirements for intraocular injections (such as intravitreal injections and anterior chamber injections) in laboratory monkeys after anesthesia are extremely strict. The core objective is to completely immobilize the head and eyeballs to prevent any accidental movement, ensure accurate and safe injection, and minimize tissue damage. When administering anesthesia injections to laboratory monkeys, they are usually required to be in a supine position to ensure that the animal's body posture is natural and comfortable, and to avoid twisting or compressing the chest cavity to affect breathing. The head position should be such that the eye to be injected is at the most convenient angle for operation.

[0003] Animals undergoing intraocular injections are typically anesthetized (deeply anesthetized) before the procedure. The risk of accidental death is high after the procedure. For example, a head fixation device for monkeys undergoing intraocular injections, as proposed in publication number CN219579116U, requires binding the torso of the experimental monkey. When animals under deep anesthesia are fully restrained, it is impossible to accurately judge certain conditioned reflexes of the animals, which may lead to accidental death.

[0004] Therefore, some existing restraint devices used for laboratory monkeys still cannot meet the needs of use. Utility Model Content

[0005] To address the technical problems existing in existing restraint devices, this utility model proposes a supine restraint device for experimental monkey eye experiments, comprising:

[0006] A support plate, wherein a sliding groove is provided on the support plate, and a rotating seat is provided on the support plate in the extending direction of the sliding groove;

[0007] A head support component is connected to the rotating base and can tilt relative to the rotating base at a predetermined angle;

[0008] A back support component is connected to the slide rail and can move relative to the support plate along the length of the slide rail to a predetermined position;

[0009] A hip support component is connected to the slide groove and can move relative to the support plate along the length of the slide groove to a predetermined position;

[0010] The groove extends in a linear direction, so that the head support component, back support component, and hip support component are distributed in a straight line. The back support component and hip support component are both located on the same side of the head support component, and the distance between the hip support component and the head support component is greater than the distance between the back support component and the head support component.

[0011] Preferably, the upper part of the rotating base is constructed as a gradually narrowing frustum-shaped structure, the rotating base is provided with an insertion hole, and the head support component is provided with a spherical connection structure, the spherical connection structure can be inserted into the insertion hole and rotate relative to the rotating base, maintaining a predetermined damping force during rotation.

[0012] Preferably, the inner wall of the socket and / or the outer wall of the spherical connecting structure are provided with an elastic layer to keep the spherical connecting structure and the socket tightly connected.

[0013] Preferably, the support surface of the head support component is provided with a groove, and the groove is constructed as a concave surface with a predetermined curvature.

[0014] Preferably, both the back support component and the hip support component include a support body and a slider extending downward from the support body into the slide groove. A damping plate is provided in the slide groove, and the support plate is also provided with a knob for driving the damping plate closer to or away from the slider. By operating the knob, the damping plate and the slider form a predetermined contact pressure.

[0015] Preferably, the damping plate has a rubber layer on the side facing the slider.

[0016] Preferably, the supporting body has extension structures on both sides perpendicular to the direction of the slide groove. The extension structures are connected to the supporting body through slide rods, so that the extension structures can maintain a predetermined distance from the supporting body.

[0017] Preferably, a removable flexible padding layer is provided above the supporting body.

[0018] Compared with the prior art, the advantages of this utility model are:

[0019] The restraint device proposed in this invention supports the experimental monkey in a supine position by supporting the head, back, and buttocks. This ensures that the experimental monkey is in an upright position, without tilting to the left or right, which is conducive to the intraocular injection position, while not restricting the experimental monkey too much. This is beneficial for observing some conditioned reflexes of the experimental monkey in a state of deep anesthesia and avoids accidental death of the experimental animal. Attached Figure Description

[0020] The accompanying drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component shown in the various figures may be denoted by the same reference numeral. For clarity, not every component is labeled in each figure. Embodiments of various aspects of the present invention will now be described by way of example and with reference to the accompanying drawings, wherein:

[0021] Figure 1This is a schematic diagram of the supine restraint device for experimental monkey eye experiments shown in this utility model;

[0022] Figure 2 This is a schematic diagram illustrating the position adjustment of the head support component and the back support component shown in this utility model;

[0023] Figure 3 This is a schematic diagram of the back support component shown in this utility model;

[0024] Figure 4 This is a schematic diagram illustrating the position adjustment of the head support component shown in this utility model. Detailed Implementation

[0025] To better understand the technical content of this utility model, specific embodiments are provided below in conjunction with the accompanying drawings.

[0026] This utility model proposes a supine restraint device for experimental monkey eye experiments, including a support plate 10, a head support component 20, a back support component 30, and a buttock support component 40.

[0027] The support plate 10 is provided with a slide groove 11, and a rotating seat 12 is provided on the support plate 10 in the extending direction of the slide groove 11. The head support component 20 is connected to the rotating seat 12 and can be tilted relative to the rotating seat 12 at a predetermined angle.

[0028] Furthermore, the back support member 30 is connected to the slide 11 and can move relative to the support plate 10 along the length of the slide 11 to a predetermined position. The hip support member 40 is connected to the slide 11 and can move relative to the support plate 10 along the length of the slide 11 to a predetermined position.

[0029] The head support component 20 is designed to support the head of the experimental monkey, the back support component 30 is designed to support the back of the experimental monkey, and the buttock support component 40 is designed to support the buttocks of the experimental monkey. The experimental monkey can be restrained by the device to support the buttocks, back and head to form a supine position.

[0030] The extension direction of the groove 11 is linear, so that the head support component 20, the back support component 30 and the hip support component 40 are distributed in a straight line.

[0031] In this way, when the experimental monkeys are restrained by the restraint device, their heads and spines naturally extend, which does not cause discomfort to the experimental monkeys.

[0032] Furthermore, the back support component 30 and the hip support component 40 are both located on the same side of the head support component 20, and the distance between the hip support component 40 and the head support component 20 is greater than the distance between the back support component 30 and the head support component 20.

[0033] In this way, the distance between the back support component 30, the buttock support component 40 and the head support component 20 can be flexibly adjusted according to the size of the experimental monkey. The smaller the experimental monkey, the closer the back support component 30 and the buttock support component 40 are to the head support component 20. The larger the experimental monkey, the farther the back support component 30 and the buttock support component 40 are from the head support component 20.

[0034] In an optional embodiment, the upper part of the rotator 12 is configured as a gradually narrowing frustum-shaped structure. The rotator 12 is provided with an insertion hole, and the head support component 20 is provided with a spherical connection structure 22. The spherical connection structure 22 can be inserted into the insertion hole and rotate relative to the rotator 12, maintaining a predetermined damping force during rotation.

[0035] It should be understood that the degree of eye socket depression, the length of the eye axis, the size of the eyeball, and the size of the brow bone will vary among different experimental monkeys. Therefore, by adjusting the angle of the head support component 20, the head of the experimental monkey can be made to form an ideal angle, so that the position of the eyeball is in an angle and position that is conducive to experimental operation. At the same time, due to the damping force between the head support component 20 and the rotating seat 12, the head can be kept at the ideal angle.

[0036] In an optional embodiment, the inner wall of the socket and / or the outer wall of the spherical connection structure 22 are provided with an elastic layer to keep the spherical connection structure 22 and the socket tightly connected.

[0037] The elastic layer can be a rubber layer. Specifically, a 3-5 mm thick rubber layer is provided on the inner wall of the socket. The surface of the spherical connecting structure 22 is provided with multiple protrusions with a height of about 1 mm. When the spherical connecting structure 22 is inserted into the socket, the protrusions squeeze the rubber layer to achieve a tight connection. That is, the head support component 20 can be rotated by the operator to a predetermined angle and can be maintained at the predetermined angle without deflection.

[0038] In other embodiments, the surface of the spherical connecting structure 22 is provided with an elastic layer, and a screw that can extend into the insertion hole is provided on the outside of the rotating base 12. When the spherical connecting structure 22 is rotated to a predetermined angle, the spherical connecting structure 22 is fixed to a predetermined position by rotating the screw.

[0039] In the above embodiment, the support surface of the head support component 20 is provided with a groove 21, which is constructed as a concave surface with a predetermined curvature.

[0040] In this way, the head of the experimental monkey can remain stable within the groove 21, preventing it from rolling freely and maintaining a suitable angle.

[0041] Furthermore, a pair of limiting blocks 23 are provided on the surface of the head support component 20. The limiting blocks 23 are located on both sides of the groove 21. When the head of the experimental monkey is in the groove 21, the limiting blocks 23 on both sides can limit the head of the experimental monkey and restrict its rotation.

[0042] Specifically, the limiting block 23 extends gradually from the bottom upwards and to both sides, forming a V-shaped limiting space between the two limiting blocks 23. The surface of the limiting block 23 is provided with a flexible skin, and the inner side is provided with an elastic pad, that is, the surface can be elastically deformed to ensure the reliability of limiting the head of the test monkey.

[0043] In an optional embodiment, both the back support component 30 and the hip support component 40 include a support body and a slider 32 extending downward from the support body 31 into the slide groove 11. A damping plate 13 is provided in the slide groove 11, and a knob 14 is provided on the support plate 10 to drive the damping plate 13 to move closer to or away from the slider 32. By operating the knob 14, the damping plate 13 and the slider 32 form a predetermined contact pressure.

[0044] Specifically, when adjusting the position of the back support component 30 or the hip support component 40, turn the knob 14 to separate the damping plate 13 and the slider 32 or reduce the contact pressure until the slider 32 can slide in the groove 11. Then push the back support component 30 or the hip support component 40 along the direction of the groove 11 until the appropriate position is reached. Then operate the knob 14 again to increase the contact pressure between the damping plate 13 and the slider 32 until the slider 32 can no longer slide in the groove 11.

[0045] In an optional embodiment, the damping plate 13 has a rubber layer on the side facing the slider 32. The rubber layer improves wear resistance and friction.

[0046] Furthermore, the supporting body 31 has extension structures 33 on both sides perpendicular to the slide groove 11. The extension structures 33 are connected to the supporting body 31 through the slide rod 34, so that the extension structures 33 can maintain a predetermined distance from the supporting body 31.

[0047] Thus, when necessary, the extension structure 33 can be pulled out to both sides according to the size of the experimental monkey to increase the support range and improve the device's adaptability to experimental monkeys of different sizes.

[0048] In a preferred embodiment, a removable flexible padding layer 35 is provided above the supporting body 31. The flexible padding layer 35 may be a flexible structure such as a sponge padding layer, designed to protect the load-bearing parts of the experimental monkey and provide better contour adaptation.

[0049] Thus, the flexible padding layer 35 can provide better support and protection for the experimental monkeys.

[0050] Furthermore, the flexible padding layer 35 is designed to conform to the contour curve of the back and buttocks of the experimental monkey. When the flexible padding layer 35 is placed on the back support component 30 or the buttock support component 40, it provides better support stability and comfort.

[0051] In conjunction with the above embodiments, the restraint device proposed in this utility model supports the experimental monkey in a supine position through three support points: head, back, and buttocks. This ensures that the experimental monkey is in an upright position, without tilting to the left or right, which is conducive to intraocular injection, while not restricting the experimental monkey too much. This is beneficial for observing some conditioned reflexes of the experimental monkey in a state of deep anesthesia and avoids accidental death of the experimental animal.

[0052] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Those skilled in the art to which this invention pertains can make various modifications and refinements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of this invention shall be determined by the claims.

Claims

1. A supine restraint device for experimental monkey eye experiments, characterized in that, include: A support plate (10) is provided with a sliding groove (11), and a rotating seat (12) is provided on the support plate (10) in the extending direction of the sliding groove (11); The head support component (20) is connected to the rotating base (12) and can tilt relative to the rotating base (12) at a predetermined angle; The back support member (30) is connected to the slide (11) and can move relative to the support plate (10) along the length direction of the slide (11) to a predetermined position; The hip support component (40) is connected to the slide (11) and can move relative to the support plate (10) along the length direction of the slide (11) to a predetermined position; The groove (11) extends in a linear direction, so that the head support component (20), back support component (30) and hip support component (40) are distributed in a straight line. The back support component (30) and hip support component (40) are both located on the same side of the head support component (20), and the distance between the hip support component (40) and the head support component (20) is greater than the distance between the back support component (30) and the head support component (20).

2. The supine positioning device for ocular experimentation in experimental monkeys according to claim 1, characterized in that, The upper part of the rotating base (12) is constructed as a gradually narrowing frustum-shaped structure. The rotating base (12) is provided with an insertion hole. The head support component (20) is provided with a spherical connection structure (22). The spherical connection structure (22) can be inserted into the insertion hole and rotate relative to the rotating base (12), maintaining a predetermined damping force during rotation.

3. The supine positioning device for ocular experimentation in experimental monkeys according to claim 2, characterized in that, The inner wall of the socket and / or the outer wall of the spherical connection structure (22) are provided with an elastic layer to keep the spherical connection structure (22) and the socket tightly connected.

4. The supine positioning device for ocular experimentation in experimental monkeys according to claim 1, characterized in that, The head support component (20) has a groove (21) on its support surface, and the groove (21) is constructed as a concave surface with a predetermined curvature.

5. The supine positioning device for ocular experimentation in experimental monkeys according to claim 1, characterized in that, Both the back support component (30) and the hip support component (40) include a support body and a slider (32) extending downward from the support body (31) into the groove (11). A damping plate (13) is provided in the groove (11). The support plate (10) is also provided with a knob (14) for driving the damping plate (13) to move closer to or away from the slider (32). By operating the knob (14), the damping plate (13) and the slider (32) form a predetermined contact pressure.

6. The supine positioning device for ocular experimentation in experimental monkeys according to claim 5, characterized in that, The damping plate (13) has a rubber layer on the side facing the slider (32).

7. The supine restraint device for experimental monkey eye experiments according to claim 5, characterized in that, The supporting body (31) has extension structures (33) on both sides perpendicular to the direction of the slide groove (11). The extension structures (33) are connected to the supporting body (31) through slide rods (34) so ​​that the extension structures (33) can maintain a predetermined distance from the supporting body (31).

8. The supine positioning device for ocular experimentation in experimental monkeys according to claim 5, characterized in that, A removable flexible pad (35) is provided above the supporting body (31).

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