Rodent tail vein administration hemostatic tape

By designing a tail vein administration hemostatic tape for rodents, the problems of complex operation and risk of leakage of traditional hemostatic tapes have been solved, which simplifies operation, improves the standardization of hemostasis, and reduces the risk of leakage.

CN224461850UActive Publication Date: 2026-07-07WUXI APPTEC (SHANGHAI) CO LTD +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
WUXI APPTEC (SHANGHAI) CO LTD
Filing Date
2025-08-04
Publication Date
2026-07-07

AI Technical Summary

Technical Problem

The current procedure for hemostasis after administration of drugs via the tail vein in rodents is complex and time-consuming, and carries the risk of drug leakage. Traditional hemostatic tapes vary greatly in their manufacturing process and are difficult to standardize.

Method used

Design a hemostatic tape for tail vein administration in rodents, comprising a bottom layer, a middle layer, and an isolation layer. The bottom layer is an adhesive layer, the middle layer is a hemostatic material layer, and the isolation layer covers the surface of the middle layer. Perforated lines are provided for easy tearing. The tape units can be assembled into a roll, simplifying the operation process.

Benefits of technology

It simplifies hemostasis procedures, reduces human error, improves the standardization and safety of hemostasis, and reduces the risk of medication leakage.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a kind of rodent tail vein drug hemostatic adhesive tape, it includes hemostatic adhesive tape unit;Hemostatic adhesive tape unit includes bottom layer, middle layer and isolation layer;Bottom layer is adhesive layer;The width of middle layer is comparable with the width of bottom layer, but length is one fifth to one third of the length of bottom layer;Middle layer is hemostatic material layer, adheres on adhesive layer, adhesive layer is separated into three sections, wherein the second section is adhered with middle layer, and the two ends are first section and third section respectively;The length of first section is between zero centimeter and the length of third section sixth and includes the end value of this numerical interval;Isolation layer is set to completely cover the upper surface of first section, middle layer and third section.This is conducive to operator single-handedly holding the hemostatic wound to be stopped and rotating hemostatic adhesive tape clockwise, and adhesive tape is pasted around the tail of rodent.
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Description

Technical Field

[0001] This utility model relates to a hemostatic tape, and more particularly to a hemostatic tape for administering medication via the tail vein of rodents. Background Technology

[0002] Rodents are the most widely used animal models in biomedical research. Tail vein administration in rodents is one of the most fundamental methods of drug delivery in pharmacokinetic studies. Hemostasis is crucial after tail vein administration in rodents, and traditionally, this involves manually preparing hemostatic tape: first, a fixed length of pressure-sensitive tape is cut, then a small cotton ball is attached to the tape, and finally, it is fixed to the wound after tail vein administration.

[0003] This hemostasis process involves two steps, and the preparation for each step is quite time-consuming. Furthermore, since the person performing the preparation varies each time, the resulting hemostatic tape can differ significantly. There is also a risk of medication leakage at the wound site. Utility Model Content

[0004] To address the aforementioned problems, this invention provides a hemostatic tape for rodent tail vein administration, comprising a hemostatic tape unit; the hemostatic tape unit includes a bottom layer, a middle layer, and an isolation layer; the bottom layer is an adhesive layer; the width of the middle layer is approximately the same as the width of the bottom layer, but its length is one-fifth to one-third of the length of the bottom layer; the middle layer is a hemostatic material layer, adhered to the adhesive layer, dividing the adhesive layer into three segments, wherein the segment with the middle layer adhered to it is the second segment, and the segments at both ends are the first and third segments, respectively; the length of the first segment is between zero centimeters and one-sixth of the length of the third segment, including both ends of this range; the isolation layer is configured to completely cover the upper surfaces of the first segment, the middle layer, and the third segment.

[0005] In some implementations, the rodent tail vein administration hemostatic tape comprises several hemostatic tape units connected end to end; perforated lines are provided between adjacent hemostatic tape units.

[0006] In some implementations, perforated lines are provided between the bottom layers of adjacent hemostatic tape units.

[0007] In some implementations, the rodent tail vein administration hemostatic tape is a roll of tape consisting of several hemostatic tape units connected end to end.

[0008] In some implementations, the bottom layer is a pressure-sensitive adhesive tape.

[0009] In some implementations, the hemostatic material layer is made of cotton or gauze.

[0010] In some implementations, the surface of the isolation layer is smooth.

[0011] In some implementations, the length of the first segment is zero centimeters.

[0012] In some implementations, the second segment is 1 cm long and the third segment is 3 cm long.

[0013] In some implementations, the width and length of the isolation layer are comparable to those of the underlying layer.

[0014] This invention modifies the design of a hemostatic tape for fixing wounds after intravenous administration of medication to rodents. The first segment of the hemostatic material layer, located near the bottom layer, is significantly shorter than the third segment, sometimes even zero centimeters in length. This allows the operator to hold the wound with one hand and rotate the tape clockwise to adhere it around the rodent's tail. The perforated lines facilitate tearing the tape unit from the tape. A smooth release liner allows for separation of the adhesive layer containing the hemostatic material layer from the release liner, preventing the release liner from carrying away the hemostatic material and adhesive. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of a rodent tail vein administration hemostatic tape provided in an embodiment of the present invention. Detailed Implementation

[0016] To make the above-mentioned objects, features, and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a full understanding of this utility model. However, this utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed below.

[0017] In the description of this utility model, it should be understood that if terms such as "longitudinal", "lateral", "length", "width", "upper", "lower", "front", "rear", "left", "right", "clockwise", "counterclockwise", etc. appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0018] Furthermore, where terms such as "first," "second," etc., appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with "first," "second," etc., may explicitly or implicitly include at least one of that feature. In the description of this utility model, where terms such as "multiple" or "several" appear, "multiple" and "several" mean at least two, such as two, three, etc., unless otherwise explicitly specified.

[0019] In this utility model, unless otherwise explicitly specified and limited, the terms "set," "connected," "linked," "fixed," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0020] In this utility model, unless otherwise explicitly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact, or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0021] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this invention are for illustrative purposes only and do not represent the only possible implementation.

[0022] In this article, "and / or" means that both can exist together, or one of them can exist. For example, A and / or B means that it can be A and B, or it can be A, or it can be B.

[0023] Example 1

[0024] Figure 1An embodiment of the rodent tail vein administration hemostatic tape of this invention is shown. In this embodiment, the rodent tail vein administration hemostatic tape is a roll of tape composed of several hemostatic tape units connected end to end.

[0025] The hemostatic tape unit includes a bottom layer 1, a middle layer 2, and an isolation layer 3. Perforated lines 4 are provided between the bottom layers of adjacent hemostatic tape units.

[0026] The bottom layer 1 is an adhesive layer, specifically pressure-sensitive adhesive tape. The width of the middle layer 2 is approximately the same as that of the bottom layer 1. The middle layer is a hemostatic material layer. The hemostatic material layer is made of gauze. The hemostatic material layer is adhered to the adhesive layer, dividing the adhesive layer into three sections. The section with the middle layer adhered to is the second section, and the sections at both ends are the first and third sections, respectively. The length of the first section is 0 cm, the length of the second section is 1 cm, and the length of the third section is 3 cm.

[0027] The isolation layer 3 is configured to completely cover the upper surfaces of the first, middle, and third segments, and its width and length are comparable to those of the bottom layer 1. The surface of the isolation layer 3 is smooth.

[0028] Usage and operation process:

[0029] During hemostasis, the operator tears off the bottom layer of a hemostatic tape unit with the middle layer along the perforation line with their right hand, presses the rodent tail vein administration hemostatic tape (with gauze covering the area) onto the tail wound of the rodent (in this example, a rat), removes the syringe with their left hand, holds the wound with their right hand and rotates the hemostatic tape clockwise to stick it around the tail once, and then rotates and fixes the remaining part.

[0030] Example 2

[0031] In the rodent tail vein administration hemostatic tape of this embodiment, the length of the first segment is one-sixth the length of the third segment. The rest is the same as in Example 1.

[0032] Example 3

[0033] In the rodent tail vein administration hemostatic tape of this embodiment, the hemostatic material layer is made of gauze, and the gauze contains at least one of the hemostatic drugs known in the art. The rest is the same as in Example 1.

[0034] Example 4

[0035] In the rodent tail vein administration hemostatic tape of this embodiment, the material used for the hemostatic material layer is cotton, and the rest is the same as in Example 1.

[0036] Example 5

[0037] In this embodiment of the rodent tail vein administration hemostatic tape, perforated lines are provided between adjacent hemostatic tape units. The rest is the same as in Embodiment 1.

[0038] Example 6

[0039] The rodent tail vein administration hemostatic tape of this embodiment also includes a cylindrical shaft, on which several hemostatic tape units connected end to end are wound. The rest is the same as in Embodiment 1.

[0040] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0041] The embodiments described above are merely illustrative of several implementations of this utility model, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model patent should be determined by the appended claims.

Claims

1. A rodent tail vein dosing hemostatic tape, characterized by, The device includes a hemostatic tape unit; the hemostatic tape unit includes a bottom layer, an intermediate layer, and a release layer; the bottom layer is an adhesive layer; the width of the intermediate layer is approximately the same as the width of the bottom layer, but the length is one-fifth to one-third of the length of the bottom layer; the intermediate layer is a hemostatic material layer, adhered to the adhesive layer, dividing the adhesive layer into three segments, wherein the segment with the intermediate layer adhered to it is the second segment, and the two ends are the first segment and the third segment, respectively; the length of the first segment is between zero centimeters and one-sixth of the length of the third segment, including both ends of this range; the release layer is configured to completely cover the upper surfaces of the first segment, the intermediate layer, and the third segment.

2. The rodent tail vein dosing hemostatic bandage of claim 1, wherein, It includes several hemostatic tape units connected end to end; perforated lines are provided between adjacent hemostatic tape units.

3. The rodent tail vein dosing hemostatic bandage of claim 2, wherein, A perforated line is provided between the bottom layers of adjacent hemostatic tape units.

4. The rodent tail vein dosing hemostatic bandage of claim 2, wherein, It is a roll of adhesive tape composed of several hemostatic tape units connected end to end.

5. The rodent tail vein dosing hemostatic bandage of claim 1, wherein, The bottom layer is pressure-sensitive adhesive tape.

6. The rodent tail vein dosing hemostatic bandage of claim 1, wherein, The hemostatic material layer is made of cotton or gauze.

7. The rodent tail vein administration hemostatic tape as described in claim 1, characterized in that, The surface of the isolation layer is smooth.

8. The rodent tail vein dosing hemostatic bandage of claim 1, wherein, The length of the first segment is zero centimeters.

9. The rodent tail vein dosing hemostatic bandage of claim 8, wherein, The second segment is 1 cm long, and the third segment is 3 cm long.

10. The rodent tail vein dosing hemostatic bandage of any one of claims 1-9, wherein, The width and length of the isolation layer are equivalent to those of the bottom layer.