A wet granulator breather

Abstract

The application belongs to the technical field of pharmaceutical production equipment, and particularly relates to a wet granulator breathing device. The breathing device is fixed on a wet granulator pot cover air vent, and comprises a membrane breathing assembly and a vibration assembly. The membrane breathing assembly comprises a breathing membrane and a support frame. The breathing membrane covers an open end of a cavity formed by the support frame, and the other open end of the breathing membrane is communicated with the wet granulator pot cover air vent. The vibration assembly comprises a vibration motor, and the vibration motor is fixed on the support frame to vibrate the breathing membrane connected with the support frame. The wet granulator breathing device provided by the application can achieve air sealing protection through the breathing membrane when the wet granulator is used. The vibration motor is started synchronously to shake off fine powder adhered to the breathing membrane, so as to prevent material blockage of the breathing membrane, reduce drug material loss caused by adhesion of drug components, and facilitate disassembly and cleaning of the device.

Description

Technical Field

[0001] This application belongs to the field of pharmaceutical production equipment technology, specifically relating to a breathing device for a wet granulation machine. Background Technology

[0002] A wet granulator is used to granulate moist powder into the desired size, or to crush lumpy dry materials into the required granules. The raw material powder is stirred by a mixing paddle, and a binder acts as a bridging agent to create adhesion between the powder particles, completing the granulation process. As a primary process equipment in wet granulation, the wet granulator is widely used in the production and processing of oral solid dosage forms.

[0003] When wet granulation machines mix raw and auxiliary materials of different compositions, especially when processing viscous or fine powder materials, some materials are too fine and can easily enter the mixing paddle shaft. Therefore, wet granulation machines often adopt an air-sealed structure. A breathing device is installed on the top cover of the wet granulation machine to maintain the pressure balance inside and outside the pot while preventing material from escaping and reducing material loss.

[0004] Chinese utility model patent application number CN202021875854.1 discloses a filter bag filter respirator for a wet granulation machine, but the respirator has problems such as easy clogging, complicated installation, and difficult cleaning.

[0005] Therefore, there is an urgent need to develop a breathing device for wet granulation machines that can ensure that it is not easily clogged and is easy to install and clean. Utility Model Content

[0006] The technical problem to be solved by this application is to provide a breathing device for a wet granulation machine, which is characterized by being less prone to clogging, easy to install and disassemble, and convenient to clean, in order to address the shortcomings of the existing technology.

[0007] The breathing device for the wet granulator provided in this application is fixed on the air vent 11 of the wet granulator pot lid. The breathing device includes a membrane breathing component and a vibration component.

[0008] The membrane breathing assembly includes a breathing membrane 1 and a support frame. The breathing membrane 1 covers one open end of the cavity formed by the support frame, and its other open end is connected to the air vent 11 of the wet granulator pot lid.

[0009] The vibration assembly includes a vibration motor 3, which is fixed to the support frame to vibrate the breathing membrane 1 connected to the support frame.

[0010] In some embodiments, the support frame includes an upper support frame 7 and a lower support frame 8, and the vibration motor 3 is fixed to the lower support frame 8.

[0011] In some implementations, the support frame is fixedly connected to the vent 11 of the wet granulator pot lid by a snap fastener 9.

[0012] In some implementations, the vibration motor 3 is fixedly connected to the lower support frame 8 by screws 2.

[0013] In some embodiments, the breathing membrane 1 is fixedly connected to the upper support frame 7 by a sealing gasket.

[0014] In some implementations, the upper support frame 7 and the lower support frame 8 are fixedly connected by threads 12.

[0015] In some embodiments, the material of the breathing membrane 1 is selected from antistatic polyester, polyester fiber, polytetrafluoroethylene, and polyphenylene sulfide.

[0016] In some embodiments, the vibration motor 3 is a pneumatic vibration motor, an electric vibration motor, or a pneumatic-electric dual-action vibration motor.

[0017] In some embodiments, the vibration assembly includes a vibration motor 3, a motor control center 15, and a power cord 4, wherein the vibration motor 3 is an electric vibration motor.

[0018] In some embodiments, the vibration assembly includes: a vibration motor 3, a motor control center 15, a compressed air line 5, an air inlet 6, a pressure gauge 13, an air valve 14, and an air compressor, wherein the vibration motor 3 is a pneumatic vibration motor.

[0019] In some embodiments, the vibration assembly includes: a vibration motor 3, a motor control center 15, a power cord 4, a compressed air pipeline 5, an air inlet 6, a pressure gauge 13, an air valve 14, and an air compressor, wherein the vibration motor 3 is a pneumatic-electric dual-action vibration motor.

[0020] In some embodiments, the buckle 9 includes a buckle size adjustment portion 16.

[0021] In some implementations, the barometer 13 displays a specific pressure value, with a pressure adjustment range of 0.1 MPa to 1 MPa.

[0022] Compared with the prior art, the beneficial effects of this application include:

[0023] The breathing device for the wet granulator provided in this application achieves an air seal protection function through the breathing membrane when using the wet granulator. Simultaneously, the vibration motor is started to keep the wet granulator breathing smoothly while shaking off the fine powder adhering to the breathing membrane, preventing the material from clogging the breathing membrane and reducing the loss of drug material caused by the adhesion of drug components.

[0024] The breathing device for the wet granulator provided in this application is fixedly connected to the vent of the wet granulator pot lid by a snap fastener, so as to fix it on the wet granulator pot lid. The breathing membrane is fixed to the upper support frame by a sealing gasket, the upper support frame is fixed to the lower support frame by threads, and the vibration motor is fixed to the lower support frame by screws. It is easy to disassemble and simple to clean. Attached Figure Description

[0025] Figure 1 This is a three-dimensional structural diagram of a wet granulator breathing device installed in a wet granulator according to one embodiment of this application;

[0026] Figure 2 This is a front cross-sectional view of the membrane breathing component of a wet granulator breathing device according to one embodiment of this application.

[0027] Figure 3 This is a top view of the breathing device of a wet granulator according to one embodiment of this application;

[0028] Figure 4 This is a schematic diagram of a three-dimensional snap-fit ​​structure according to one embodiment of this application;

[0029] Figure 5 This is a front view schematic diagram of a breathing device for a wet granulator with a pneumatic-electric dual-action vibration motor according to one embodiment of this application.

[0030] Figure 6 This is a side view schematic diagram of a breathing device for a wet granulator, which is an embodiment of a pneumatic-electric dual-action vibration motor according to this application.

[0031] Figure 7 This is a front view schematic diagram of a vibration assembly of an electric vibration motor, which is another embodiment of this application;

[0032] Figure 8 This is a front view schematic diagram of a vibration assembly of a pneumatic vibration motor according to another embodiment of this application.

[0033] The following are the annotations for each of the attached figures: 1. Breathing membrane; 2. Screw; 3. Vibration motor; 4. Power cord; 5. Compressed air pipeline; 6. Air inlet; 7. Upper support frame; 8. Lower support frame; 9. Buckle; 10. Wet granulator lid; 11. Wet granulator lid vent; 12. Thread; 13. Pressure gauge; 14. Air valve; 15. Motor control center; 16. Buckle size adjustment part. Detailed Implementation

[0034] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.

[0035] In this application, unless otherwise expressly specified and limited, the terms "assembly," "fixing," etc., should be interpreted broadly. For example, "fixing" can mean a fixed connection, a detachable connection, or an integral part; unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0036] If the breathing device of this application is not used, existing wet granulation machine breathing devices suffer from problems such as easy clogging, cumbersome installation, and difficult cleaning. Using the wet granulation machine breathing device described in this application reduces clogging during granulation and is easier to install and clean. To make the technical solution of this application clearer, the technical solution of this application will be clearly and completely described below with examples.

[0037] As one implementation method, the breathing device of the wet granulator is installed in the three-dimensional structural diagram of the wet granulator, as shown in the figure. Figure 1 As shown, it includes a breathing membrane 1; screws 2; a vibration motor 3; a power cord 4; a compressed air pipeline 5; an air inlet 6; an upper support frame 7; a lower support frame 8; and a buckle 9.

[0038] As one implementation method, the breathing device of the wet granulator is as follows: Figure 1-3 As shown, the wet granulator breathing device provided in this embodiment includes a membrane breathing assembly and a vibration assembly. The membrane breathing assembly includes a breathing membrane 1, an upper support frame 7, and a lower support frame 8. The breathing membrane 1 is fixed to the upper support frame 7 by a sealing gasket to support the breathing membrane 1 and keep it fixed and flat. The upper support frame 7 and the lower support frame 8 are fixed by threads 12. The vibration assembly includes a vibration motor 3, which is fixed to the lower support frame 8 by screws 2.

[0039] As one implementation method, the structure of the snap-fit ​​9 is as follows: Figure 4As shown, the breathing device provided in this embodiment is fixedly connected to the vent 11 of the wet granulator lid via a buckle 9. Specifically, the lower support frame 8 is fixedly connected to the vent 11 of the wet granulator lid via a buckle 9. The diameter of the lower support frame 8 is the same as or larger than the diameter of the vent 11. The opening of the vent 11 of the wet granulator lid has an upwardly extending opening end relative to the wet granulator lid 10. The support frame is installed on and connected to the upwardly extending opening end of the vent 11 of the wet granulator lid. The buckle 9 is provided at the connection between the support frame and the vent 11 of the wet granulator lid, and the breathing device is fixed at the vent 11 of the wet granulator lid by adjusting the buckle size adjustment part 16.

[0040] One embodiment is a breathing device for a wet granulation machine with a dual-action pneumatic-electric vibration motor, such as... Figure 5 , 6 As shown. The vibration assembly includes a vibration motor 3, a power cord 4, a compressed air pipeline 5, an air inlet 6, a pressure gauge 13, an air valve 14, and a motor control center 15. The motor control center 15 controls the vibration motor 3 to vibrate the upper support frame 7 and the lower support frame 8, thereby vibrating the breathing membrane 1.

[0041] Another implementation is a vibration component of an electric vibration motor, such as... Figure 7 As shown, the vibration assembly includes a vibration motor 3, a power cord 4, and a motor control center 15. The vibration motor 3 is fixed to the lower support frame 8 by screws 2. One end of the power cord 4 is directly connected to the motor control center 15, and the other end is connected to the power supply. After the power cord 4 is connected to the power supply, the motor control center 15 controls the vibration motor 3 to vibrate the upper support frame 7 and the lower support frame 8, thereby vibrating the breathing membrane 1.

[0042] Another implementation is a vibration component of a pneumatic vibration motor, such as... Figure 8 As shown, the vibration assembly includes a vibration motor 3, a compressed air pipeline 5, an air inlet 6, a pressure gauge 13, an air valve 14, and a motor control center 15. One end of the compressed air pipeline 5 is connected to the motor control center 15, and the other end is connected to an air compressor. By controlling the air compressor, the pressure gauge 13, and the air valve 14, the high-pressure gas is controlled to control the vibration motor 3 to vibrate the upper support frame 7 and the lower support frame 8, thereby vibrating the breathing membrane 1.

[0043] The vibration motor 3 can adjust its vibration frequency using compressed air or electricity. The adjustable pressure range for compressed air is 0.01MPa-1.0MPa, and the adjustable power range for electricity is 100W-1000W. When using the wet granulation machine, the vibration motor 3 shakes off the fine powder adhering to the breathing membrane 1, preventing material blockage, balancing the internal and external air pressure of the breathing membrane, preventing material loss, and improving mixing efficiency.

[0044] In this embodiment, the upper support frame 7, the lower support frame 8, and the vibration motor 3 of the wet granulator breathing device are all made of metal. The breathing membrane 1 is circular, square, or other shapes, and its material can be antistatic polyester, polyester fiber, polytetrafluoroethylene, polyphenylene sulfide, etc., including but not limited to the above materials.

[0045] The model of this breathable breathing device can be adjusted according to the model of the wet granulation pan. The size, material, and pore size of the breathing membrane 1 can all be adjusted according to different preparation requirements. The power source of the vibration motor 3 can be adjusted according to different models of wet granulation machines and the relevant configuration of different production sites. Compressed air or electricity can be selected as the vibration power source, and the vibration frequency can be adjusted by the compressed air pressure or power to adapt to different production needs.

[0046] The breathing device for the wet granulator provided in this embodiment uses a breathing membrane 1 as a filter breather. Before operation, the appropriate material, size, and pore size of the breathing membrane 1 must be selected according to the work requirements. After installation, the upper support frame 7 and the lower support frame 8 are installed and fixed. Then, according to the working requirements of the wet granulator, the pneumatic vibration motor pressure gauge 13 is adjusted. The pressure setting range is 0.1MPa-1.0MPa, or the electric vibration motor is set to a suitable power, with a power setting range of 100W-1000W. If a pneumatic vibration motor is used, the piston can be driven to reciprocate by the high-pressure gas generated by the air compressor, thereby generating vibration. The wet granulator and vibration motor 3 are started. The stirring and shearing inside the wet granulator lifts the fine powder. The fine powder adhering to the breathing membrane 1 then falls into the wet granulator pot through vibration and is remixed. After granulation, the device can be disassembled by opening the buckle 9. The upper support frame 7 and the lower support frame 8 can be separated by the screw, which is simple to disassemble and easy to clean. This device has a simple structure and is easy to use. It effectively solves the problems of easy clogging, complicated installation, and difficult cleaning of the filter bag breathing device commonly used in existing wet granulation machines, which can easily lead to material contamination. It has high practical value.

[0047] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A breathing device for a wet granulation machine, characterized in that, The breathing device is fixed on the air vent (11) of the wet granulation machine pot lid. The breathing device includes a membrane breathing component and a vibration component. The membrane breathing assembly includes a breathing membrane (1) and a support frame. The breathing membrane (1) covers one open end of the cavity formed by the support frame, and its other open end is connected to the vent (11) of the wet granulator pot lid. The vibration assembly includes a vibration motor (3), which is fixed to the support frame to vibrate the breathing membrane (1) connected to the support frame.

2. The breathing device for a wet granulator according to claim 1, characterized in that, The support frame includes an upper support frame (7) and a lower support frame (8), and the vibration motor (3) is fixed on the lower support frame (8).

3. The breathing device for a wet granulator according to claim 1, characterized in that, The support frame is fixedly connected to the vent (11) of the wet granulator pot lid by a buckle (9).

4. The breathing device for a wet granulator according to claim 2, characterized in that, The vibration motor (3) is fixedly connected to the lower support frame (8) by screws (2).

5. The breathing device for a wet granulator according to claim 2, characterized in that, The breathing membrane (1) is fixedly connected to the upper support frame (7) by a sealing gasket.

6. The breathing device for a wet granulator according to claim 2, characterized in that, The upper support frame (7) and the lower support frame (8) are fixedly connected by threads (12).

7. The breathing device for a wet granulator according to claim 1, characterized in that, The material of the breathing membrane (1) is selected from one of antistatic polyester, polyester fiber, polytetrafluoroethylene, and polyphenylene sulfide.

8. The breathing device for a wet granulator according to claim 1, characterized in that, The vibration motor (3) is a pneumatic vibration motor, an electric vibration motor, or a pneumatic-electric dual-action vibration motor.

9. The breathing device for a wet granulator according to claim 1, characterized in that, The vibration assembly includes: a vibration motor (3), a motor control center (15), and a power cord (4), wherein the vibration motor (3) is an electric vibration motor; or The vibration assembly includes: a vibration motor (3), a motor control center (15), a compressed air pipeline (5), an air inlet (6), a pressure gauge (13), an air valve (14), and an air compressor, wherein the vibration motor (3) is a pneumatic vibration motor.

10. The breathing device for a wet granulator according to claim 1, characterized in that, The vibration assembly includes: a vibration motor (3), a motor control center (15), a power cord (4), a compressed air pipeline (5), an air inlet (6), a pressure gauge (13), an air valve (14), and an air compressor, wherein the vibration motor (3) is a pneumatic-electric dual-action vibration motor.

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