Automatic radio-pharmaceutical dispensing apparatus

Abstract

The utility model discloses a kind of radioactive medicine automatic split packer. The split packer includes shell body and the medicine bottle protective cover, split packing protective cover, liquid medicine split packing transfer catheter and cup stand mechanism set in its inside. It also includes diaphragm pump, solenoid valve and breather needle connected in sequence, breather needle is inserted into liquid medicine dilution bottle. When solenoid valve is powered, diaphragm pump starts to make the negative pressure inside liquid medicine dilution bottle, and the original liquid in original liquid bottle can be sucked into liquid medicine dilution bottle under the action of negative pressure. When solenoid valve is powered off, breather needle is communicated with the space inside shell body, which is convenient for liquid medicine extraction. The utility model is provided with diaphragm pump and solenoid valve, which can not only automatically suck the original liquid in original liquid bottle by negative pressure, but also meet the extraction of diluted liquid medicine in liquid medicine dilution bottle, and the setting is scientific and reasonable, and split packing is more accurate. Through the improvement of medicine bottle protective cover, the existing hole protective cover is saved, pollution is avoided, and the top lead cover is set as horizontal push-pull structure, which is simple to operate and saves time and effort.

Description

Technical Field

[0001] This utility model relates to the field of radiopharmaceutical dispensing technology, and in particular to an automatic radiopharmaceutical dispensing instrument. Background Technology

[0002] Radiopharmaceuticals are a class of special drugs containing radioactive nuclides used for medical diagnosis and treatment, such as I-131 radiotherapy for hyperthyroidism patients. Radiopharmaceuticals require repackaging before clinical use. Currently, many radiopharmaceuticals are drawn and repackaged using syringes. This process is time-consuming, difficult to operate, and inaccurate, failing to meet the precise needs of each patient and affecting treatment or examination results. Furthermore, the repackaging process leads to prolonged radiation exposure for operators, posing a significant risk to medical personnel.

[0003] Existing radiopharmaceutical dispensing equipment still suffers from problems such as inaccurate dispensing, inconvenient operation, and poor shielding effect. Based on these issues, this application creates a new automatic radiopharmaceutical dispensing instrument that can automatically absorb radiopharmaceutical concentrate and meet the dispensing requirements. It has a simple and convenient structure, is safe and feasible, and improves the ease of operation and dispensing safety through the improvement of the protective cover. This is a target that the industry urgently needs to improve. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide an automatic radiopharmaceutical dispensing instrument, which can realize the automatic aspiration of radiopharmaceutical concentrate and meet the dispensing requirements through the combination of diaphragm pump and solenoid valve. It has a simple and convenient structure, is safe and feasible, and improves the convenience of operation and enhances the dispensing safety through the improvement of protective cover, thereby overcoming the shortcomings of existing automatic radiopharmaceutical dispensing instruments.

[0005] To solve the above-mentioned technical problems, this utility model provides an automatic radiopharmaceutical dispensing instrument, including an outer shell. Inside the outer shell are a bottle protector for holding a drug dilution bottle, a dispensing protector for mounting a drug dispensing and transfer conduit, and a cup holder mechanism for holding a drug receiving cup. A drive mechanism is also provided to move a syringe connected to the drug dispensing and transfer conduit by inserting and removing it. The drug dispensing and transfer conduit includes at least three three-way valves connected in series. The ends of the three-way valves are respectively used to connect a syringe, a diluent extraction needle, a concentrate extraction needle, a drinking water extraction tube, and a drug discharge tube. The outer shell also includes a diaphragm pump, a solenoid valve, and a venting device. The diaphragm pump's air inlet is connected to the first port of the solenoid valve, the second port of the solenoid valve is connected to the air needle, and the third port of the solenoid valve is connected to the internal space of the outer casing. When the solenoid valve is energized, its first port is connected to its second port, and the diaphragm pump can create a negative pressure inside the drug dilution bottle. Under the action of negative pressure, the original liquid in the original liquid bottle can be drawn into the drug dilution bottle. When the solenoid valve is de-energized, its third port is connected to its second port, realizing the connection between the drug dilution bottle and the internal space of the outer casing, which facilitates the extraction of drug liquid from the drug dilution bottle by the syringe connected to the drug dispensing and transfer conduit.

[0006] In a further improvement, the medicine bottle protective cover is composed of a top lead cap, a bottom lead base, and four side lead blocks. The inner wall of the side lead blocks is provided with an activity detector for detecting the activity of the medicine solution in the medicine dilution bottle. The side lead blocks near the middle of the outer shell are provided with a first clearance hole for the conduit that passes through the medicine bottle protective cover.

[0007] In a further improvement, the top lead cover adopts a horizontal sliding structure, the top lead cover is provided with a movable handle, and the outer shell is provided with an unlocking mechanism for controlling the opening and closing of the top lead cover.

[0008] As a further improvement, the unlocking mechanism employs a resilient locking pin.

[0009] As a further improvement, the lead block thickness of the medicine bottle protective cover is 60mm.

[0010] In a further improvement, a second clearance hole is provided on the side lead block near the outside of the outer shell for the conduit connected to the original liquid bottle to pass through. The outside of the outer shell is also provided with a hose protective cover for protecting the conduit connected to the original liquid bottle before it enters the second clearance hole.

[0011] In a further improvement, the outer casing also includes an independent three-way valve whose first port is connected to a drinking water extraction pipe, the second port of the independent three-way valve is connected to one of the ports of the medicine dispensing and transfer conduit, and the third port of the independent three-way valve is blocked.

[0012] In a further improvement, the cup holder mechanism includes a cup holder for holding a medicine receiving cup, a flexible tube holder for installing a medicine discharge tube, and a three-bar linkage, as well as a power mechanism for driving the cup holder to extend and retract. The middle part of the flexible tube holder is rotatably fixed to a vertical plate located in the outer shell via a pin. The outer end of the flexible tube holder is configured with an L-shaped structure. The three-bar linkage includes a horizontal push block, a triangular block, and a vertical rod. One end of the horizontal push block abuts against the inner side of the cup holder, and the other end is hinged to the first corner end of the triangular block. The second corner end of the triangular block is rotatably connected to the vertical plate. The third triangular end of the triangular block is hinged to the bottom end of the vertical rod, and the top end of the vertical rod is hinged to the inner end of the flexible tube holder. When the cup holder moves inward under the action of the power mechanism, it drives the horizontal push block to move inward, pushes the triangular block to rotate, and then pushes the vertical rod to move upward, causing the inner end of the flexible tube holder to rotate upward, and then causing the outer end of the flexible tube holder to rotate downward, causing the outlet end of the medicine discharge tube to come close to the inner wall of the medicine receiving cup, preventing splashing when the medicine is discharged.

[0013] In a further improvement, a return spring is connected to the inner end of the hose holder, and the other end of the return spring is connected to the bottom of the upright plate to control the hose holder to return to its original position when the cup holder moves outward.

[0014] In a further improvement, the power mechanism adopts a gear and rack transmission mechanism, and the outer shell is provided with an automatic opening and closing door. The power mechanism drives the cup holder and the medicine receiving cup to extend out of the outer shell from the opening of the automatic opening and closing door.

[0015] With this design, the present invention has at least the following advantages:

[0016] 1. This utility model of an automatic radiopharmaceutical dispensing instrument, by setting a diaphragm pump and a solenoid valve in the outer shell, can not only automatically draw the original liquid from the original liquid bottle using negative pressure, but also meet the requirements for extracting the diluted drug solution from the drug dilution bottle. The setting is scientific and reasonable, and the dispensing is more accurate.

[0017] 2. Furthermore, improvements to the medicine bottle protective cover eliminate the need for the existing perforated protective cap, preventing contamination. The top lead cap is designed as a horizontal push-pull structure, allowing for simple horizontal pushing and pulling during operation, avoiding the need to rotate and lift the existing protective cap. This saves time and effort, significantly improving operational convenience and safety. Additionally, the addition of a hose protective cover further enhances the protection of the through-tube between the outer and lower housings, making it safer and more reliable.

[0018] 3. The independent three-way valve facilitates disassembly and allows for flexible and adaptable assembly layouts in small spaces.

[0019] 4. Furthermore, improvements to the cup holder mechanism enable linkage between the medicine receiving cup and the medicine discharge pipe. The discharge port of the medicine discharge pipe adheres tightly to the inner wall of the receiving cup as the medicine flows out, allowing the medicine to flow smoothly and effectively preventing splashing during discharge, thus further enhancing safety. Additionally, the inclusion of a return spring ensures the automatic return of the flexible hose holder when the cup holder extends, preventing it from interfering with the movement of the medicine receiving cup. Attached Figure Description

[0020] The above is merely an overview of the technical solution of this utility model. In order to better understand the technical means of this utility model, the following describes this utility model in further detail with reference to the accompanying drawings and specific embodiments.

[0021] Figure 1 This is a perspective view of the right side of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0022] Figure 2 This is a perspective view of the left side of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0023] Figure 3 This is a perspective view of the rear structure of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0024] Figure 4 This is a schematic diagram of the top structure of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0025] Figure 5 This is a schematic diagram of the structure of the solenoid valve when it is energized in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0026] Figure 6 This is a schematic diagram of the structure of the solenoid valve in the automatic radiopharmaceutical dispensing instrument of this utility model when it is de-energized.

[0027] Figure 7 This is a schematic diagram of the original solution transfer structure in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0028] Figure 8 This is a schematic diagram of the structure for transferring drug solution in the dilution bottle of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0029] Figure 9 This is a schematic diagram of the water transfer structure in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0030] Figure 10 This is a schematic diagram of the structure of the protective cover for the medicine bottle in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0031] Figure 11 This is a schematic diagram of the protective cover of the medicine bottle in the ready-to-open state of the automatic radiopharmaceutical dispensing instrument of this utility model.

[0032] Figure 12 This is a schematic diagram of the medicine bottle protective cover after it is opened in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0033] Figure 13 This is a schematic diagram of the cup holder mechanism in the automatic radiopharmaceutical dispensing instrument of this utility model.

[0034] Figure 14 This is a schematic diagram of the cup holder mechanism in the automatic radiopharmaceutical dispensing instrument of this utility model (showing the state of drug flow). Detailed Implementation

[0035] Exemplary embodiments of the present invention will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the present invention are shown in the drawings, it should be understood that the present invention may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

[0036] See attached document Figures 1 to 4 As shown, the automatic radiopharmaceutical dispensing instrument of this embodiment includes an outer casing 1.

[0037] The outer casing 1 contains a bottle protective cover 25 for holding the drug dilution bottle 26, a dispensing protective cover 19 for installing the drug dispensing and transfer conduit 15, and a cup holder mechanism 12 for holding the drug receiving cup 13, as well as a drive mechanism 17 for moving the syringe 16 connected to the drug dispensing and transfer conduit 15. The drug dispensing and transfer conduit 15 uses three three-way valves connected in series and one separate three-way valve 30 connected in series. The ends of the three-way valves connected in series are respectively connected to the syringe 16, the diluent extraction needle 21, the concentrate extraction needle, the drinking water extraction tube 27, and the drug discharge tube 14. The outer casing 1 also includes an exhaust pipe 20 with an exhaust fan 18, which is used to connect to an exhaust gas collection pipe to achieve centralized collection and treatment of polluted air inside the outer casing 1.

[0038] In this embodiment, the outer casing 1 also includes a diaphragm pump 29, a solenoid valve 31, and a vent needle 23. (See attached...) Figure 5 and 6 As shown, the air inlet of the diaphragm pump 29 is connected to the first port C of the solenoid valve 31, the second port A of the solenoid valve 31 is connected to the vent needle 38, and the third port B of the solenoid valve 31 communicates with the internal space of the outer casing 1. When the solenoid valve 31 is energized, its first port C and second port A are connected, and the diaphragm pump 29, when activated, creates a negative pressure inside the drug dilution bottle 26. This negative pressure forces the original solution in the original solution bottle 32 into the drug dilution bottle 26, as shown in the attached diagram. Figure 7As shown; when the solenoid valve 31 is de-energized, its third port B is connected to its second port A, enabling communication between the drug dilution bottle 26 and the internal space of the outer casing 1, facilitating the extraction of the drug solution from the drug dilution bottle 26 by the syringe 16 connected to the drug solution dispensing and transfer conduit 15, as shown in the attached figure. Figure 8 As shown. In this embodiment, the diaphragm pump 29 and the solenoid valve 31 are located on the outside of the medicine bottle protective cover 25, and the connecting conduit between the solenoid valve 31 and the vent needle 38 passes through the side wall of the medicine bottle protective cover 25.

[0039] See attached document Figure 10 As shown, in this embodiment, the medicine bottle protective cover 25 is composed of a top lead cap 22, a bottom lead base 251, and four side lead blocks 252, with a lead block thickness of 60mm. The inner wall of each side lead block 252 is equipped with an activity detector 42 for detecting the activity of the medicine solution in the medicine dilution bottle 26. A first clearance hole 253 is provided on each side lead block 252 near the middle of the outer casing 1 for a conduit penetrating the medicine bottle protective cover 25 to pass through. The top lead cap 22 is opened and closed by a push-pull mechanism, and the outer casing 1 is equipped with an unlocking mechanism, such as a spring-loaded locking pin 24, for controlling the opening and closing of the top lead cap 22. (See attached...) Figure 11 and 12 As shown, when the medicine bottle protective cover 25 needs to be opened, simply pull out the elastic locking pin 24, and the top lead cover 22 can be easily pulled by the handle 221. This overcomes the drawback of the existing top lead cover needing to be lifted. Furthermore, because the top lead cover is very heavy, it is easy to hit the outer shell when it is fastened, which may cause damage to the outer shell or pose a safety hazard.

[0040] Furthermore, a second clearance hole is provided on the side lead block 252 near the outside of the outer casing 1 for the conduit connected to the original liquid extraction needle 33 to pass through. The outer casing 1 is also provided with a flexible tubing protective cover 28, as shown in the attached figure. Figure 1 and 4 As shown, this is for protection before the tubing connected to the original solution extraction needle 33 enters the second clearance hole. The tubing protective cover 28 can be rotated open for easy installation of the tubing.

[0041] In this embodiment, the independent three-way valve 30 can be omitted, allowing the water bottle extraction tube 27 to be directly connected to one port of the three-way valves connected in series, thus still enabling water extraction from the water bottle. The independent three-way valve 30, being separately designed, is easy to disassemble, facilitating structural arrangements for existing small-space dispensing scenarios, and offers flexible design and wide adaptability.

[0042] See attached document Figure 13 and 14As shown, the cup holder mechanism 12 in this embodiment includes a cup holder 121 for placing a medicine receiving cup 13, a flexible tube holder 122 for installing a medicine discharge pipe 14, and a three-bar linkage, as well as a power mechanism for driving the cup holder 121 to extend and retract. The power mechanism can be a gear and rack mechanism for driving the cup holder 121 to extend and retract. The middle part of the flexible tube holder 122 is rotatably fixed to a vertical plate 123 located in the outer shell 1 via a pin, and the outer end of the flexible tube holder 122 is configured with an L-shaped structure. The three-bar linkage includes a horizontal push block 124, a triangular block 125, and a vertical rod 126. One end of the horizontal push block 124 abuts against the inner side of the cup holder 121, and the other end is hinged to the first corner end of the triangular block 125. The second corner end of the triangular block 125 is rotatably connected to the upright plate 123. The third triangular end of the triangular block 125 is hinged to the bottom end of the upright rod 126. The top end of the upright rod 126 is hinged to the inner end of the hose frame 122, and the inner end of the hose frame 122 is also connected to a return spring 127. The other end of the return spring 127 is connected to the bottom of the upright plate 123. When the cup holder 121 moves inward under the action of the power mechanism, it drives the horizontal push block 124 to move inward, pushes the triangular block 125 to rotate, and then pushes the upright rod 126 to move upward, causing the inner end of the hose frame 122 to rotate upward, and then causing the outer end of the hose frame 122 to rotate downward, causing the outlet end of the medicine discharge pipe 14 to come close to the inner wall of the medicine receiving cup 13, preventing splashing when the medicine is discharged. When the cup holder 121 extends outward under the action of the power mechanism, the return spring 127 rebounds and causes the inner end of the hose bracket 122 to rotate downward, thereby causing the outer end of the hose bracket 122 to rotate upward above the medicine receiving cup 13, so that its L-shaped end does not affect the medicine receiving cup 13 extending outward with the cup holder 121.

[0043] For example, see attached Figure 1 As shown, the outer casing 1 is provided with an automatic opening and closing door 11 corresponding to the cup holder mechanism 12. The power mechanism drives the cup holder 121 and the medicine receiving cup 13 to extend out of the outer casing 1 from the opening of the automatic opening and closing door 11 for direct access by the patient.

[0044] The above-mentioned automated radiopharmaceutical dispensing instrument includes the following steps when dispensing radiopharmaceuticals:

[0045] (1) Install the original solution extraction needle 33, the drug solution dilution bottle 26, the dilution solution extraction needle 21, the ventilation needle 23, the drug solution dispensing and transfer tubing 15 and the syringe 16, the independent three-way valve 30, the drinking water bottle and the drug solution receiving cup 13 respectively, and complete the connection of the corresponding tubing;

[0046] (2) Start the diaphragm pump 29 and the solenoid valve 31. The negative pressure generated by the diaphragm pump 29 transfers the stock solution in the stock solution bottle 32 to the drug solution dilution bottle 26, as shown in the attached figure. Figure 7 As shown, the diaphragm pump 29 and solenoid valve 31 are shut off after the transfer is completed;

[0047] (4) Based on the patient's required amount of medication and the activity value of the medication in the medication dilution bottle 26, the medication in the medication dilution bottle 26 is drawn out by the syringe 16 connected to the medication dispensing and transfer catheter 15, as shown in the attached figure. Figure 8 As shown, the extracted medicine is discharged through the medicine discharge pipe 14 into the medicine receiving cup 13;

[0048] (5) Then, drinking water is drawn from the drinking water bottle through syringe 16 connected to the drug solution dispensing and transfer conduit 15, as shown in the attached figure. Figure 9 As shown, the extracted drinking water is discharged through the medicine discharge pipe 14 into the medicine receiving cup 13;

[0049] (6) Open the door 11 of the outer shell 1, and the cup holder mechanism 12 sends the medicine receiving cup 13 out of the outer shell 1 to complete the medicine dispensing for the patient to drink.

[0050] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any way. Any simple modifications, equivalent changes or alterations made by those skilled in the art using the above-disclosed technical content shall fall within the protection scope of the present utility model.

Claims

1. An automatic radiopharmaceutical dispensing device, comprising an outer casing, wherein the outer casing contains a bottle protective cover for holding a drug dilution bottle, a dispensing protective cover for mounting a drug dispensing transfer conduit, and a cup holder mechanism for holding a drug receiving cup, and a drive mechanism for moving a syringe connected to the drug dispensing transfer conduit by insertion and removal, wherein the drug dispensing transfer conduit includes at least three three-way valves connected in series, the ends of which are respectively used to connect a syringe, a diluent extraction needle, a concentrate extraction needle, a drinking water extraction tube, and a drug discharge tube, characterized in that, The outer casing also includes a diaphragm pump, a solenoid valve, and a vent needle. The air inlet of the diaphragm pump is connected to the first port of the solenoid valve, the second port of the solenoid valve is connected to the vent needle, and the third port of the solenoid valve communicates with the internal space of the outer casing. When the solenoid valve is energized, its first port is connected to its second port, and the diaphragm pump can create a negative pressure inside the drug dilution bottle. Under the action of negative pressure, the original solution in the original solution bottle can be drawn into the drug dilution bottle. When the solenoid valve is de-energized, its third port is connected to its second port, realizing communication between the drug dilution bottle and the internal space of the outer casing, which facilitates the extraction of drug solution from the drug dilution bottle by a syringe connected to the drug dispensing and transfer conduit.

2. The automatic radiopharmaceutical dispensing apparatus according to claim 1, characterized in that, The medicine bottle protective cover is composed of a top lead cap, a bottom lead base, and four side lead blocks. The inner wall of the side lead blocks is provided with an activity detector for detecting the activity of the medicine liquid in the medicine dilution bottle. The side lead blocks near the middle of the outer shell are provided with a first clearance hole for the conduit that passes through the medicine bottle protective cover.

3. The automatic radiopharmaceutical dispensing apparatus according to claim 2, characterized in that, The top lead cover adopts a horizontal sliding structure, the top lead cover is provided with a movable handle, and the outer shell is provided with an unlocking mechanism for controlling the opening and closing of the top lead cover.

4. The automatic radiopharmaceutical dispensing apparatus according to claim 3, characterized in that, The unlocking mechanism uses a resilient locking pin.

5. The automatic radiopharmaceutical dispensing apparatus according to claim 2, characterized in that, The lead block thickness of the medicine bottle protective cover is 60mm.

6. The automatic radiopharmaceutical dispensing apparatus according to claim 2, characterized in that, The side lead block near the outside of the outer shell is provided with a second clearance hole for the conduit connected to the original liquid bottle to pass through. The outside of the outer shell is also provided with a hose protective cover for protecting the conduit connected to the original liquid bottle before it enters the second clearance hole.

7. The automatic radiopharmaceutical dispensing apparatus according to claim 1, characterized in that, The outer casing also includes an independent three-way valve whose first port is connected to a drinking water extraction pipe, the second port of the independent three-way valve is connected to one port of the medicine dispensing and transfer conduit, and the third port of the independent three-way valve is blocked.

8. The automated radiopharmaceutical dispensing apparatus according to any one of claims 1 to 7, characterized in that, The cup holder mechanism includes a cup holder for holding a medicine receiving cup, a flexible tube holder for installing a medicine discharge tube, and a three-bar linkage, as well as a power mechanism for driving the cup holder to extend and retract. The middle part of the flexible tube holder is rotatably fixed to a vertical plate located in the outer shell via a pin. The outer end of the flexible tube holder is configured with an L-shaped structure. The three-bar linkage includes a horizontal push block, a triangular block, and a vertical rod. One end of the horizontal push block abuts against the inner side of the cup holder, and the other end is hinged to the first corner end of the triangular block. The second corner end of the triangular block is rotatably connected to the vertical plate. The third triangular end of the triangular block is hinged to the bottom end of the vertical rod. The top end of the vertical rod is hinged to the inner end of the flexible tube holder. When the cup holder moves inward under the action of the power mechanism, it drives the horizontal push block to move inward, pushes the triangular block to rotate, and then pushes the vertical rod to move upward, causing the inner end of the flexible tube holder to rotate upward, and then causing the outer end of the flexible tube holder to rotate downward, causing the outlet end of the medicine discharge tube to come close to the inner wall of the medicine receiving cup, preventing splashing when the medicine is discharged.

9. The automatic radiopharmaceutical dispensing apparatus according to claim 8, characterized in that, The inner end of the hose holder is also connected to a return spring, and the other end of the return spring is connected to the bottom of the upright plate to control the hose holder to return to its original position when the cup holder moves outward.

10. The automatic radiopharmaceutical dispensing apparatus according to claim 9, characterized in that, The power mechanism adopts a gear and rack transmission mechanism, and the outer shell is provided with an automatic opening and closing door. The power mechanism drives the cup holder and the medicine receiving cup to extend out of the outer shell from the opening of the automatic opening and closing door.

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