Modular fully automated protein chromatography purification system

The modularly designed fully automated protein chromatography purification system integrates a plunger pump, an ultraviolet detector, and a pressure sensor, and combines them with an industrial control computer to achieve automated control. This solves the problems of complex operation and low efficiency of existing equipment, and achieves efficient and accurate protein purification.

CN224485032UActive Publication Date: 2026-07-14LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES(LANZHOU BRANCH CENTER OF CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER) +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES(LANZHOU BRANCH CENTER OF CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER)
Filing Date
2025-07-14
Publication Date
2026-07-14

AI Technical Summary

Technical Problem

Existing protein purification equipment is complex to operate, time-consuming, inefficient, and lacks automation, making it difficult to guarantee the accuracy and stability of purification results. Furthermore, its functions are limited and cannot meet the needs of scientific research and production.

Method used

The modular, fully automated protein chromatography purification system integrates a high-precision plunger pump, an ultraviolet detector, and a real-time pressure sensor. It achieves automated control and data management through an industrial control computer, and features accurate ultraviolet absorption detection and pressure monitoring. It also supports multi-task parallel processing and real-time adjustment of experimental parameters.

Benefits of technology

It has achieved automated control of the protein purification process, improved operational convenience and work efficiency, ensured experimental safety and data accuracy, adapted to experimental needs of different scales, and reduced the risk of equipment damage.

✦ Generated by Eureka AI based on patent content.

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    Figure CN224485032U_ABST
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Abstract

A kind of modular full-automatic protein chromatography purification system, it is related to the technical field of biopharmaceutical equipment, including shell, piston pump, pressure sensor and ultraviolet detector are equipped on the outer wall of shell side, fluid inlet end of piston pump is connected external sample solution device, fluid outlet end is connected the inlet of external chromatographic column by pipeline;Pressure sensor is connected on the pipeline between piston pump and external chromatographic column;Ultraviolet detector is connected at the outlet of external chromatographic column by pipeline;Front surface of shell is inlaidly provided with industrial computer, industrial computer is connected piston pump, pressure sensor and ultraviolet detector respectively by serial communication;Man-machine interaction page is configured on industrial computer, man-machine interaction page includes system function area, data display area and curve display area.The utility model can realize the automation control of protein purification process, with accurate ultraviolet absorption detection, pressure detection and perfect data management function.
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