An incubation box for traditional drug molecule group polypeptide detection analysis

Abstract

The utility model relates to the technical field of incubation box, and disclose a kind of for traditional medicine molecule group polypeptide detection analysis incubation box, including base, the top of base is equipped with stepper motor, the top of stepper motor output shaft is fixedly connected with driving shaft, driving shaft's outer ring is equipped with driving gear, the top of base is also rotatably connected with driven shaft, the outer ring of driven shaft is equipped with driven gear, driven gear and driving gear are mutually engaged, the top of driven shaft is equipped with heating mechanism, heating mechanism is provided with multiple groups and is circumferentially arrayed distribution in the outer ring of driven shaft.The utility model can preheat specific heating area to target temperature, when the incubation box is put in, the required temperature environment can be obtained immediately by accurate rotation, the time delay of sample from room temperature to target temperature in traditional equipment is completely eliminated, and the antigen-antibody reaction can be fully carried out according to the theoretical time set in the reagent kit instruction.

Description

Technical Field

[0001] This utility model relates to the field of incubation box technology, specifically an incubation box for the detection and analysis of peptides in traditional drug molecular groups. Background Technology

[0002] Traditional medicines, as an important part of the pharmaceutical treasure trove, have always had a focus in drug research regarding the identification and quality control of their active ingredients. Peptides, as key bioactive components in traditional medicines, possess various pharmacological effects, including anticoagulation, antithrombosis, inhibition of platelet aggregation, and improvement of blood rheological parameters. In recent years, with the development of biotechnology, peptide detection and analysis techniques have become a crucial tool for the modernization of traditional medicine research.

[0003] In implementing the above-mentioned scheme, the applicant discovered that in peptide detection analysis, the completion of the antigen-antibody reaction requires a specific temperature environment and sufficient time. Ideally, the microplate containing the sample and reagents should be preheated to the target temperature before being placed into the incubation device. However, in practice, after the microplate is transferred from room temperature to the incubation device, the liquid temperature in each well needs time to rise from room temperature to the set target temperature. This results in the actual effective reaction time being shorter than the theoretical time set in the kit instructions. For weakly positive samples or low-concentration peptide samples, the antigen-antibody reaction may not proceed sufficiently, easily leading to false negative results or an increased detection limit, significantly reducing sensitivity. Therefore, this invention designs an incubation box for peptide detection analysis of traditional drug molecular genomes to solve the above problems. Utility Model Content

[0004] The purpose of this invention is to provide an incubation box for the detection and analysis of peptides in traditional drug molecular groups, which solves the problem of excessively long temperature control time in the prior art.

[0005] To solve the above-mentioned technical problems, this utility model provides the following technical solution: An incubation box for detecting and analyzing peptides in traditional drug molecular genomes includes a base, a stepper motor mounted on the top of the base, a drive shaft fixedly connected to the top of the stepper motor's output shaft, a drive gear mounted on the outer ring of the drive shaft, a driven shaft rotatably connected to the top of the base, a driven gear mounted on the outer ring of the driven shaft, the driven gear meshing with the drive gear, and a heating mechanism mounted on the top of the driven shaft, wherein multiple heating mechanisms are arranged in a circumferential array on the outer ring of the driven shaft.

[0006] Preferably, a bracket is fixedly connected to the top of the base, and a support frame is installed on one side of the bracket for placing the incubation unit.

[0007] Preferably, the heating mechanism includes a heating cylinder fitted around the outer ring of the driven shaft, and heating wires are installed in the inner cavity of the heating cylinder in an S-shaped arrangement.

[0008] Preferably, a connecting plate is fixedly connected to the top of the heating cylinder for uniform heat distribution, the heating cylinder is arranged in multiple circumferential arrays, and a protective cylinder is fixedly connected to the top of the base.

[0009] Preferably, the bottom of the support frame is provided with heating holes, which are distributed in multiple circumferential arrays. The inner wall of the support frame is provided with a placement groove, and a culture box is installed in the inner cavity of the placement groove. The placement groove and the culture box are distributed in multiple circumferential arrays.

[0010] Preferably, the top of the bracket is hinged with a sealing cap, and a handle is installed on one side of the sealing cap.

[0011] Compared with the prior art, the beneficial effects achieved by this utility model are: 1. This utility model can preheat a specific heating area to the target temperature. When the incubation box is placed in, the required temperature environment can be obtained immediately by precise rotation. This completely eliminates the time delay of the sample rising from room temperature to the target temperature in traditional equipment, ensuring that the antigen-antibody reaction can be carried out fully according to the theoretical time set in the kit instructions.

[0012] 2. This invention, due to its more precise and timely temperature control, effectively avoids the problem of insufficient reaction caused by the heating process in weak positive samples or low-concentration peptide samples. At the same time as the sample completes the incubation, another heating unit is already preheated and ready, which greatly improves the continuity of experimental operation and work efficiency. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a side view of the structure of this utility model; Figure 3 This is a schematic diagram of the internal structure of this utility model; Figure 4 This is a side view of the internal structure of this utility model; Figure 5 This is a partial sectional view of the present invention.

[0014] The components include: 1. Base; 2. Stepper motor; 3. Drive shaft; 4. Drive gear; 5. Driven shaft; 6. Driven gear; 7. Bracket; 8. Support frame; 9. Heating cylinder; 10. Heating wire; 11. Protective cylinder; 12. Heating hole; 13. Placement slot; 14. Incubation box; 15. Sealing cover; 16. Handle; 17. Connecting piece. Detailed Implementation

[0015] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0016] Please refer to Figures 1-5 An incubation box for detecting and analyzing peptides in traditional drug molecular genomes includes a base 1, a stepper motor 2 mounted on the top of the base 1, a drive shaft 3 fixedly connected to the top of the output shaft of the stepper motor 2, a drive gear 4 mounted on the outer ring of the drive shaft 3, a driven shaft 5 rotatably connected to the top of the base 1, a driven gear 6 mounted on the outer ring of the driven shaft 5, the driven gear 6 meshing with the drive gear 4, and a heating mechanism mounted on the top of the driven shaft 5, with multiple heating mechanisms arranged in a circumferential array on the outer ring of the driven shaft 5.

[0017] A bracket 7 is fixedly connected to the top of the base 1, and a support frame 8 is installed on one side of the bracket 7 for placing the incubation unit.

[0018] The heating mechanism includes a heating cylinder 9 fitted around the outer ring of the driven shaft 5. Heating wires 10 are installed inside the heating cylinder 9 and are arranged in an S-shape. A connecting piece 17 is fixedly connected to the top of the heating cylinder 9 for uniform heat distribution. The heating cylinder 9 is arranged in multiple circumferential arrays. A protective cylinder 11 is fixedly connected to the top of the base 1.

[0019] In this embodiment of the invention, the heating wire 10 inside each heating cylinder 9 can be independently adjusted in power to achieve differentiated temperature control in different areas. The system can preheat the heating cylinder 9 in a specific area to the target temperature, while other areas can maintain room temperature or different temperature states. This zoned temperature control method eliminates the need for overall heating of the equipment, significantly reducing energy consumption and shortening preheating time. The stepper motor 2 drives the driven gear 6 to rotate via the drive shaft 3 and drive gear 4, causing the driven shaft 5 and its heating mechanism to perform circular motion. When incubation is required, the system precisely controls the rotation angle to rotate the preheated heating cylinder 9 to directly below the heating hole 12 at the bottom of the support frame 8, immediately heating the incubation box 14. During incubation, the system can operate continuously. After a group of incubation boxes 14 has completed incubation, the rotating mechanism can rotate the preheated new heating cylinder 9 to the working position, while simultaneously moving the cooling heating cylinder 9 back to the preheating area for temperature recovery.

[0020] Please refer to Figures 1-5The bottom of the support frame 8 is provided with heating holes 12, which are distributed in multiple circumferential arrays. The inner wall of the support frame 8 is provided with a placement groove 13, and a culture box 14 is installed in the inner cavity of the placement groove 13. The placement groove 13 and the culture box 14 are distributed in multiple circumferential arrays.

[0021] A sealing cover 15 is hinged to the top of the bracket 7, and a handle 16 is installed on one side of the sealing cover 15.

[0022] In this embodiment of the invention, the connecting piece 17 at the top of the heating cylinder 9 is made of a highly thermally conductive material to ensure rapid and uniform heat transfer. The heating holes 12 at the bottom of the support frame 8 are precisely aligned with the heating cylinder 9 to minimize heat loss and improve heat conduction efficiency. The system, through precise control of the rotation angle and speed of the stepper motor 2, combined with an independent temperature control system, can achieve switching between multiple heating modes. The closing of the sealing cover 15 ensures the thermal insulation of the working environment, making temperature control more precise and stable.

[0023] In use, the heating wire 10 inside each heating cylinder 9 can be independently adjusted in power to achieve differentiated temperature control in different areas. The system can preheat the heating cylinder 9 in a specific area to the target temperature, while other areas can maintain room temperature or different temperature states. The stepper motor 2 drives the driven gear 6 to rotate through the drive shaft 3 and drive gear 4, causing the driven shaft 5 and its heating mechanism to perform circular motion. When incubation is required, the system precisely controls the rotation angle to rotate the preheated heating cylinder 9 to directly below the heating hole 12 at the bottom of the support frame 8, immediately heating the incubation box 14. During incubation, the system can operate continuously. After a set of incubation boxes 14 has completed incubation, the rotating mechanism can rotate the preheated new heating cylinder 9 to the working position, while moving the cooling heating cylinder 9 back to the preheating area for temperature recovery.

[0024] The connecting piece 17 at the top of the heating cylinder 9 is made of a highly thermally conductive material to ensure rapid and uniform heat transfer. The heating holes 12 at the bottom of the support frame 8 are precisely aligned with the heating cylinder 9 to minimize heat loss and improve heat conduction efficiency. The system, through precise control of the rotation angle and speed of the stepper motor 2, combined with an independent temperature control system, can switch between multiple heating modes. The closed sealing cover 15 ensures thermal insulation of the working environment, making temperature control more precise and stable.

[0025] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An incubation cartridge for traditional drug molecule group polypeptide detection analysis, characterized in that, Includes a base (1), a stepper motor (2) is mounted on the top of the base (1), a drive shaft (3) is fixedly connected to the top of the output shaft of the stepper motor (2), a drive gear (4) is mounted on the outer ring of the drive shaft (3), a driven shaft (5) is rotatably connected to the top of the base (1), a driven gear (6) is mounted on the outer ring of the driven shaft (5), the driven gear (6) meshes with the drive gear (4), a heating mechanism is mounted on the top of the driven shaft (5), and multiple sets of the heating mechanism are arranged in a circumferential array on the outer ring of the driven shaft (5); The top of the base (1) is also fixedly connected to a bracket (7), and a support frame (8) is installed on one side of the bracket (7) for placing the incubation unit.

2. The incubation box for detecting and analyzing traditional drug molecules group polypeptides according to claim 1, characterized in that: The heating mechanism includes a heating cylinder (9) fitted around the outer ring of the driven shaft (5), and an electric heating wire (10) is installed in the inner cavity of the heating cylinder (9) and the electric heating wire (10) is distributed in an S-shape.

3. The incubation box for detecting and analyzing polypeptides in traditional drug molecular biology according to claim 2, characterized in that: The top of the heating cylinder (9) is fixedly connected to a connecting piece (17) for uniform heat distribution. The heating cylinder (9) is arranged in multiple circumferential arrays. The top of the base (1) is fixedly connected to a protective cylinder (11).

4. The incubation box for detecting and analyzing peptides in traditional drug molecular biology according to claim 1, characterized in that: The bottom of the support frame (8) is provided with heating holes (12), which are distributed in multiple circumferential arrays. The inner wall of the support frame (8) is provided with a placement groove (13), and a culture box (14) is installed in the inner cavity of the placement groove (13). The placement groove (13) and the culture box (14) are distributed in multiple circumferential arrays.

5. The incubation box for detecting and analyzing traditional drug molecules group polypeptides according to claim 1, characterized in that: The top of the bracket (7) is hinged with a sealing cap (15), and a handle (16) is installed on one side of the sealing cap (15).

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