Device for stimulating the biosynthesis of vitamin D3

Description

[0001] The present invention, which is defined in independent claims 1, 15 and 23, relates to a device for stimulating the biosynthesis of vitamin D3, as well as a computer program product for controlling such a device. Technological background

[0002] Vitamins are essential substances for the body, participating in numerous metabolic reactions and influencing the immune system. Among vitamins, vitamin D plays a special role. Vitamin D is a lipophilic compound that can be synthesized by most vertebrates through exposure to ultraviolet light on the skin. This is primarily due to the UV-B component of sunlight, i.e., light radiation with wavelengths between 280 nm and 315 nm.

[0003] In many latitudes or when performing activities that take place primarily indoors or at night, it may be necessary to supplement vitamin D3. In addition to foods containing vitamin D, vitamin D can also be taken as a dietary supplement. It is important that an appropriate fat or oil is also taken when taking vitamin D tablets to facilitate absorption. In principle, in environments where it is not possible to maintain vitamin D levels at an adequate level through daily exposure to a certain amount of sunlight or through appropriate supplements, it is possible to utilize the skin's biosynthesis through light irradiation, just as would happen with sun exposure. For example, visits to a tanning salon even with a short exposure time can be sufficient to maintain the body's own vitamin D3 biosynthesis at an adequate level.Products are increasingly appearing on the market that advertise daily lighting solutions that are supposed to support vitamin D3 biosynthesis. However, it's important to note that UV radiation, particularly in the wavelength range between 280 nm and 315 nm, can damage the eyes. UV types A and B are generally absorbed by the lens of the eye, so over time, clouding can occur and lead to cataracts that require surgical treatment. In addition, there is a certain risk of cancer from this UV radiation, so it's preferable to limit exposure to controlled exposure and avoid prolonged exposure.

[0004] In particular, occupational groups that regularly have to work night shifts or people who live in places where daily sunlight is very low or completely absent, especially in the winter months, benefit greatly from lighting that facilitates the body's own natural biosynthesis of vitamin D3. In the pandemic year of 2020, a scientific study also found strong evidence that UV-B radiation, supported by vitamin D3 synthesis, can have a protective effect against a severe course of COVID-19 (Evidence of protective role of ultraviolet-B (UVB) radiation in reducing COVID-19 deaths [Moozhipurath, RK, Kraft, L. and Skiera, B., Sei Rep 10, 17705

[2020] ).

[0005] For the purposes of the present invention, and without being bound to this theory, a biosynthesis of vitamin D3 and its corresponding derivatives is assumed for the irradiation, which can be synthesized with ultraviolet light in wavelengths between 290 and 315 nm, i.e. wavelengths in the UV-B range with an energy of at least half the minimal erythema dose (MED). For this purpose, 7-dehydrocholesterol is broken down by a photochemically induced reaction of the B ring, forming previtamin D3. This previtamin D3 is unstable and reacts to form vitamin D3. In the blood, it is bound to the vitamin D-binding protein and transported to the liver, where it is hydroxylated to calcitriol. The required precursor, i.e. 7-dehydrocholesterol, is produced by the body itself.

[0006] In summary, there is a need for devices that can stimulate or at least support the body's own biosynthesis of vitamin D3. These devices should have as few harmful side effects as possible during use. KR 2015 0124016 A discloses a device according to the preamble of claim 1. Description of the invention

[0007] It is therefore an object of the present invention to provide a device of the type mentioned above that overcomes at least one disadvantage of the known device. In particular, such a device is to be provided that is safe in use and can have a measurable effect on the vitamin D3 content in the blood. It is a further object of the present invention to provide a computer program product that is suitable for controlling such a device and enables safe operation of such a device.

[0008] It is a further particular object of the present invention to provide such a device and a corresponding computer program product which inhibits or substantially prevents damage to the lenses of the eye due to their use.

[0009] At least one of these objects has been achieved with a device and a computer program product according to the characterizing part of the independent claims.

[0010] One aspect of the present invention relates to a device for stimulating the biosynthesis of vitamin D3. The device comprises at least one first illuminant for emitting light radiation comprising wavelengths in a range of between 280 nm and 315 nm. The device further comprises a sensor unit for detecting an irradiation area. It further comprises a directing unit for aligning the at least one illuminant to the irradiation area. In addition, the device according to the invention comprises a control unit designed to identify the irradiation area and to trigger an emission of light radiation comprising wavelengths in a range of between 280 and 315 nm by the at least one illuminant.

[0011] One advantage of the device according to the invention can be that the sensor unit can ensure that the emission of light radiation is only initiated when an irradiation area is detected that is safe for irradiation. This can be determined, for example, based on predefined criteria.

[0012] It has surprisingly been found that with a device according to the invention, an irradiation area, e.g. a skin area of ​​a person, can be irradiated with sufficient light radiation comprising wavelengths in particular in the UV-B range in order to stimulate or at least support the body's own production of vitamin D and at the same time remain below a minimal erythema dose for a fair-skinned person.

[0013] For the purposes of the present invention, the minimum erythema dose is the threshold above which erythema, i.e. the sun halo effect, can be observed on the skin. The minimum erythema dose varies for different skin types and is also subject to individual fluctuations. For the present invention, for example, it can be assumed as a reference that an irradiation dose of approximately 12.5 mJ / cm2 for a period of between 10 and 15 minutes is sufficient to stimulate vitamin D3 biosynthesis in a person with skin type 2. For the purposes of the present invention, skin type can be understood as being classified according to Fitzpatrick into the following types: I (very light), II (light), III (medium light), IV (brownish, olive), V (light brown, dark) and VI (dark brown to black) [TB Fitzpatrick: Ultraviolet-induced pigmentary changes: Benefits and hazards. In: Therapeutic Photomedicine. (= Current Problems in Dermatology.Volume 15). Karger, 1986, pp. 25-38].

[0014] In a particular embodiment, the light source comprises at least one LED. For the purposes of the present invention, a light source for emitting light radiation comprising wavelengths in a range between 280 nm and 315 nm is understood to mean a light source that covers at least a partial range of this spectrum. UV LEDs with a spectrum between 280 and 315 nm are also suitable, as are LEDs that have a peak in said spectrum range. Suitable light sources can be determined by a person skilled in the art.

[0015] LEDs offer another advantage: surprisingly, it was found that LEDs can be used even more effectively to stimulate vitamin D3 biosynthesis than natural sunlight. (Kalajian, TA, Aldoukhi, A., Veronikis, AJ et al. Ultraviolet B Light Emitting Diodes (LEDs) Are More Efficient and Effective in Producing Vitamin D3 in Human Skin Compared to Natural Sunlight. Sci Rep 7, 11489 (2017)).

[0016] Particularly preferably, the luminous means is designed to emit light radiation comprising wavelengths in a range of between 290 nm and 300 nm.

[0017] In the sense of the present invention, a directing unit can be understood, for example, as a mechanical arrangement which is suitable for directing the at least one first illuminant and / or at least the light radiation of the at least one first illuminant onto an irradiation area. This can be achieved, for example, by a directing unit being movable and / or pivotable on at least one axis. Preferably, the directing unit is movable and / or pivotable on at least two axes, such that preferably a conical area, starting from the at least one first illuminant, can be traversed by the directing unit, such that a plurality of irradiation areas can be detected within this conical area.

[0018] In a particular embodiment, the alignment unit is designed to align the at least one illuminant in an angular range of 180°.

[0019] In a particular embodiment, the control unit comprises at least one processor designed to execute a computer program suitable for evaluating data received from the sensor unit. This evaluation is designed, for example, to identify a specific irradiation area. The control unit can be designed to carry out corresponding processes as soon as an irradiation area has been identified. These processes can, for example, comprise emitting light radiation in the said wavelengths, or switching off the emission of light radiation in the said wavelengths. Furthermore, these processes can be designed to initiate alignment by the alignment unit. If detection of an irradiation area occurs continuously, the control unit can, for example, be designed to give instructions to the alignment unit to follow a specific path and, within a cone, for exampleThe aiming unit can detect a suitable irradiation area. Once identified, the control unit can then trigger the emission of light radiation at the specified wavelengths.

[0020] In a particular embodiment, the sensor unit comprises an optical sensor. In particular, the optical sensor is a camera. In principle, all sensor elements which are capable of detecting an irradiation area over a certain distance are suitable for a sensor unit according to the invention. It has been shown that optical sensors are particularly suitable. The sensor unit can specifically comprise a sensor, e.g. a camera. It can also comprise further sensors, such as a rangefinder. Suitable rangefinders can, for example, be provided on the basis of laser rangefinders, which are capable of emitting a laser beam and thereby accurately measuring a distance to an object. This has the particular advantage that the device can use the controller to precisely determine an intensity for the illuminant which takes into account the distance of the irradiation area from the illuminant.This will allow for optimal stimulation of vitamin D3 biosynthesis and ensure that light radiation is applied in such a way that it remains below the critical erythema dose.

[0021] The optical sensor can also be designed to capture infrared images. A sensor equipped in this way can, for example, track the effect of light radiation on a treatment area. This can further assist in maintaining the minimum erythema dose. Furthermore, based on the thermal gradients, it can be possible to determine a specific energy value applied to the treatment area. This can then be used, for example, to calculate the delivery of a sufficient dose of the light radiation.

[0022] In a particular embodiment, the device comprises a plurality of sensor units, each with one or more sensors, in particular optical sensors.

[0023] In a particular embodiment, the control unit is designed to control an alignment of the first illuminant by the alignment unit based on an identified irradiation area. In this embodiment, for example, a sensor unit can be equipped with an optical sensor that covers a specific area. The area can be broadly defined using a wide-angle lens. If a suitable irradiation area within this area is detected by the sensor unit and identified by the control unit, the control unit can, for example, cause the alignment unit to align the illuminant to this area. For this purpose, the control unit can be designed to define the irradiation area based on a vector in the image area of ​​the optical sensor and to cause the alignment unit to align the illuminant based on this vector.

[0024] In a particular embodiment, the device according to the invention comprises a collection unit for generating a directed beam from the emission of light radiation by the first illuminant. The collection unit is preferably designed to direct the light radiation to a limited irradiation area. For this purpose, the collection unit has, for example, elements that allow the light radiation to be kept within a certain space over the distance from the irradiation area, so that the irradiation area is defined as precisely as possible.

[0025] In a particular embodiment, the collection unit comprises at least one reflector. For example, an LED can be used as the light source, and a corresponding reflector arranged around the LED can be provided, which directs the light radiation emitted by the LED onto a specific irradiation area. Particularly preferably, an adjustable reflector unit is provided. An adjustable reflector unit can be made possible, for example, with a plurality of activatable reflector planes, which can accommodate, for example, a specific distance or angle of the irradiation area relative to the light source.

[0026] In a particular embodiment, the collecting unit comprises a lens and / or a collimator. Particularly preferably, the collecting unit comprises a collimator with a collecting lens for generating a directed beam of light from the emission of light radiation by the first illuminant. Depending on the design of the device, its final size, and its positioning relative to the irradiation area, the collecting unit can be configured differently by a specialist if necessary.

[0027] In a particular embodiment, the device according to the invention comprises a second illuminant for emitting light radiation comprising wavelengths in the visible range. The second illuminant is particularly preferably designed to emit light radiation comprising wavelengths in a range of between 380 nm and 780 nm. By emitting visible light, the operation of the device according to the invention can ideally be monitored by a person. Thus, this second illuminant can preferably be designed to irradiate the same irradiation area as the first illuminant. The generated "light cone" allows the user to see that a specific irradiation area is currently being exposed to the corresponding light radiation. For example,The user is encouraged to keep the area still for the duration of the irradiation, thus ensuring that the device can deliver the defined and optimal amount of radiation to optimally perform the intended stimulation of vitamin D3 biosynthesis.

[0028] In a particular embodiment, the device according to the invention comprises a third illuminant for emitting light radiation comprising wavelengths in the near-infrared range. These wavelengths are particularly preferably in a range between 640 nm and 1,800 nm. Without being bound by this theory, exposing the irradiated area to radiation in the near-infrared range can improve blood circulation in this area. Near-infrared radiation is used to promote blood circulation in the deeper layers of the tissue. This can further stimulate vitamin D3 biosynthesis, which in turn makes it possible to further reduce the dose of UV-B radiation.

[0029] In a particular embodiment, the control unit is designed to identify a human face in an irradiation area. This can be done, for example, by comparing an irradiation area detected by a sensor unit with a database. Methods for facial recognition are now known and are widely used. Modern cameras, e.g. as installed in current mobile phones, have facial recognition to support the appropriate sharpness of the image recording. For the purposes of the present invention, facial recognition which detects the presence of a face and cannot necessarily assign the face to a specific person is sufficient. Nevertheless, it would be conceivable to use facial recognition to identify a specific person. This can, for example, make it possible to deliver a specific dose to a person over a specific period of time using the device according to the invention.The device can thus determine that the person in question has been exposed to sufficient light radiation within a certain period of time to stimulate the corresponding biosynthesis of vitamin D3. Two-dimensional and three-dimensional methods for facial recognition suitable for use in the present invention are known to those skilled in the art and can be adapted to requirements as needed, e.g., depending on whether mere recognition of the presence of a face or the assignment of a face to a specific person is desired.

[0030] In a particular embodiment, the control unit is designed to recognize the face of a minor and exclude this person from irradiation. In a particular embodiment, the control unit is designed to compare a recognized face with a register approved for irradiation. This ensures that only approved and / or authorized users use the device according to the invention.

[0031] In a particular embodiment, the control unit is designed to identify a predefined irradiation area. For example, an irradiation area that has already been irradiated can be understood as a predefined irradiation area, so that the control unit is able to identify an irradiation area that has already been irradiated and, upon a second irradiation within a certain time interval, decides on a different irradiation area. This can ensure that a daily dose of UV-B radiation for a specific irradiation area is not exceeded. It would also be conceivable for the control unit to be designed to recognize predefined irradiation areas that are excluded from irradiation. For example, irradiation areas that are areas of skin containing scar tissue, wound tissue, scabs, tattoos, skin changes such as nevi and the like can be excluded from irradiation.Such predefined irradiation areas can be stored in a memory, or they can be calculated from the identified irradiation area, similar to how facial recognition occurs by capturing individual objects two-dimensionally or three-dimensionally and then identifying them using algorithmic methods.

[0032] In a particular embodiment, the device according to the invention comprises a communication unit for exchanging data. The communication unit particularly preferably comprises at least one interface for data transmission with a computer device, which can also include a modern mobile phone. This interface can be suitable for enabling wireless data transmission, e.g. by means of a WiFi protocol or a Bluetooth®< protocol. However, the interface can also be suitable for ensuring data transmission by means of a plug and cable connection based on a USB protocol. Using a communication unit, it is possible, for example, to monitor or configure an evaluation of an operation by the device according to the invention on a third-party device. For example, use can provide that certain user data, such as skin type, age, occupation and lifestyle, is stored in a profile.The device can be designed to ensure optimal support of vitamin D3 biosynthesis based on this data. The communication unit can also be designed, for example, to keep the device's programming, in the form of firmware, up to date. It is also conceivable that the communication unit enables a connection to a machine-learning-based program, which, for example, can continuously improve facial recognition. Additional functions would then include the detection of other user areas excluded from irradiation, such as moles or wounds, as described above.

[0033] In a particular embodiment, the first illuminant and / or the second illuminant and / or the third illuminant are physically coupled around the sensor unit. Thus, they can be directed jointly towards the irradiation area by the directing unit. This arrangement is particularly advantageous if the device according to the invention is to have a "search and find" function, in which it actively identifies a suitable irradiation area. For example, a motion sensor can be provided in the sensor unit, which detects that a person is located within an effective range of the device according to the invention. The sensor unit can then begin to detect specific irradiation areas and identify them via the control unit. The control unit can cause a directing unit to search for a suitable irradiation area within the effective range of the device until one is found.

[0034] In a particular embodiment, the alignment unit is designed to be pivotable along at least two axes. Particularly preferably, it comprises at least one rotatably mounted base and a rotatably mounted tool arm for pivoting the illuminant along at least two axes. Such a configuration makes it possible to extend the effective range of the device according to the invention to a hemisphere on the plane on which the device is placed. Due to the movement along two axes, the entire space within this main sphere can be detected by the sensor unit.

[0035] In a particular embodiment, the irradiation area is a skin area with an area of ​​between 40 cm 2 and 900 cm 2 , in particular between 50 cm 2 and 600 cm 2 , particularly preferably approximately 400 cm 2 . Further suitable irradiation protocols can be found by a person skilled in the art, for example, in the study by Kalajian, TA, Aldoukhi, A., Veronikis, AJ et al and Moozhipurath, RK et al.

[0036] In a particular embodiment, the skin area of ​​this irradiation zone can be defined by a regulated collector unit. For this purpose, the collector unit can, for example, have an adjustable aperture that can expand or narrow the cone of the light beam accordingly, allowing the irradiation zone to be defined within certain parameters.

[0037] The device according to the invention provides a device which enables the stimulation of vitamin D3 biosynthesis in a targeted manner and with good control of possible side effects.

[0038] A further aspect of the present invention relates to a computer program product for controlling a device for stimulating vitamin D3 biosynthesis. Particularly preferably, the computer program product is executed by a control unit of the device described above. The computer program is designed to compare an irradiation area detected by a sensor unit with predefined irradiation areas. It is further designed to trigger an emission of light radiation comprising wavelengths in a range of between 280 nm and 315 nm by at least one first illuminant. This occurs when the detected irradiation area does not correspond to an irradiation area excluded from irradiation.

[0039] The computer program product according to the invention can thus ensure that the irradiation always complies with health requirements. Particularly preferably, the appropriate irradiation areas can be predefined.

[0040] In a particular embodiment, an irradiation area excluded from irradiation is an irradiation area selected from the group consisting of: a human face, a skin area provided with one or more pigment nevi, a skin area provided with scab, wound and / or scar tissue, and a skin area already irradiated within a predefined time interval with light radiation comprising wavelengths in a range of between 280 nm and 315 nm.

[0041] In a particular embodiment, an irradiation zone excluded from irradiation is an irradiation zone belonging to a person who is not authorized to use the device. This can be ensured, for example, through registration and by storing a facial image as a biometric means of identification. Furthermore, minors can be excluded from using the device in this way.

[0042] In a particular embodiment, the computer program product is designed to assign a time interval to a specific irradiation area. Within this time interval, the irradiation area is to be irradiated with light radiation comprising wavelengths in a range of between 280 and 315 nm. This can be done, for example, in operation with the device mentioned, in that the control unit identifies a specific irradiation area and recognizes it as suitable. The irradiation is initiated and a specific time interval is determined in which the irradiation is to take place. This time interval can be fixed, e.g. a time interval of between half a minute and ten minutes, in particular between one and eight minutes, further in particular between three and five minutes, or it can be variable and defined based on parameters that, for example,have been previously stored with a user profile, which can include skin type, vitamin D requirements, lifestyle, etc. For example, it is known that the darker the skin type, the longer you need to stay in the sun until a sufficient amount of vitamin D3 can be synthesized. Furthermore, a lifestyle that takes place primarily at night or beyond a latitude where daily exposure to sunlight falls below a certain level can also be a reason to adjust the corresponding time intervals. A medical history can also be a reason to make a corresponding adjustment, for example a disorder in vitamin D metabolism or a special need for vitamin D due to age and / or medical conditions.

[0043] In a particular embodiment, the computer program product is designed to control a search for a predefined irradiation area by controlling the sensor unit. If no suitable irradiation area is found, the sensor unit can be designed to perform a search by scanning the entire effective area and identifying a possible irradiation area.

[0044] In a particular embodiment, the computer program product is designed to compare each image captured by an optical sensor with an irradiation area excluded from irradiation.

[0045] This ensures that an area that is not intended for irradiation is not accidentally exposed to radiation.

[0046] In a particular embodiment, the computer program product is designed to initiate an operating mode based on a signal from the sensor unit, in particular to search for a suitable irradiation area that is not excluded from irradiation. This signal can be, for example, a motion detection signal.

[0047] In a further particular embodiment, the computer program product is designed to initiate exposure of an irradiation area to light radiation comprising wavelengths in a range between 280 and 315 nm as soon as a sensor unit detects an irradiation area excluded from irradiation within the effective range of the light source. This can occur, for example, if an irradiated person moves or another person enters this irradiation area, so that it can no longer be guaranteed that an area excluded from irradiation, such as a face, will not be affected by the radiation.

[0048] The device according to the invention and the corresponding computer program product provide a means for stimulating vitamin D3 biosynthesis that can be used in many areas. The device shown is safe to use and prevents many negative side effects of irradiation with UV-B radiation, i.e., radiation in a wavelength range between 280 and 315 nm.

[0049] The device according to the invention will now be explained in more detail below using specific exemplary embodiments and figures, without, however, being bound to them. However, these specific exemplary embodiments will reveal further advantageous embodiments of the device according to the invention to the person skilled in the art.

[0050] In particular, the figures illustrate an implementation in a schematic manner, wherein the same element is provided with the same reference number for easier tracing. Character description

[0051] Embodiments of the invention are described with reference to the following figures.

[0052] They show: Fig. 1a a device according to the invention for stimulating the biosynthesis of vitamin D3. Fig. 1b the device of Fig. 1a in frontal view; Fig. 1c a cross-section through the device of the Fig. 1b in the plane CC; Fig. 1 side view of the device of the Fig. 1b ; Fig. 1e a side cross-section of the device of Fig. 1b in the plane AA; Fig. 1 fine side cross-section of the device of Fig. 1b in the plane BB; Fig. 1g an exploded view of the device of the Fig. 1a ; Fig. 1a detailed view of a lamp of the Fig. 1a; Fig. 1 an alternative arrangement of a lighting means for a device according to Fig. 1a ; Fig. 2 shows an alternative embodiment of a device according to the invention; Fig. 3a shows a further alternative embodiment of a device according to the invention in front view, and Fig. 3b shows the device according to the invention according to Fig. 3a in isometric view. Implementation of the invention

[0053] In the Fig. 1aA device 1 according to the invention for stimulating the biosynthesis of vitamin D3 is shown. The device 1 is suitable, for example, for use in private areas and as a supplement to a healthy and conscious lifestyle. The device 1 comprises a housing 10. In the present example, the housing 10 is made of aluminum using a deep-drawing process. Housings made of plastic, stainless steel, or ceramic are of course also suitable. A particular advantage of aluminum is its good thermal conductivity, which can help dissipate any waste heat to the environment. The housing 10 is shell-shaped and bordered on one front side by a front panel 11. The front panel 11 has two glass windows 12 through which light radiation can penetrate from the interior of the housing 10 to the outside. Although glass window 12 is mentioned here, the viewing window shown can also be made of a plastic, e.g.Plexiglas. Ideally, the glass is selected so that it is essentially transparent to UV-B radiation in the wavelengths between 280 nm and 315 nm. A suitable UV-permeable glass is shown, for example, in US Pat. No. 5,474,589 A (Sumitomo Electric Industries Ltd.).

[0054] The light source can be seen through the glass window 12. In the present example, the light source consists of an array 17, which has a plurality of UV LEDs 21. The array 17 is mounted horizontally displaceably in that it is mounted in a light source frame via a light source carriage 18. The housing 10 is connected to a base 41 via a stand 52 connected to the housing 10 by a bearing joint. For fastening on an edge, the base 41 has a gripper, comprising a first gripper 50.1 and a second gripper 50.2, which close a holding groove running centrally between the first and second grippers 50.1, 50.2. The first and second grippers 50.1, 50.2 are preferably rubberized, so that additional friction is created and the grip of the gripper is improved. The device 1 shown has a power connection via a cable connection 38, which ends in a USB / power plug 39.In the center of the front panel 11 is the camera lens 13, behind which a camera is installed as an optical sensor.

[0055] The Fig. 1a The device 1 shown can be placed, for example, on the upper edge of a computer screen, a television or a tripod device, and a basic adjustment of the alignment of the device 1 can be made via the stand 52. The camera lens 13 can monitor a front area and detect any irradiation areas therein. If an irradiation area is controlled by a control unit (in the Fig. 1anot shown) and the irradiation area is not subject to a reservation, i.e. if the irradiation area is not an irradiation area excluded from irradiation, light radiation is emitted via the lamp, or in the present example, by the UV LED 21. For this purpose, the LEDs 21 can have corresponding reflectors, which focus the light radiation and limit it accordingly to the irradiation area (in the Fig. 1a not shown).

[0056] During operation, the device 1 can exchange numerous data with a corresponding computer. For example, the USB / power connector 39 can be used to monitor operating parameters such as operating time, temperature, irradiation duration of individual irradiation areas, and how often a specific irradiation area had to be avoided (e.g., the face).

[0057] The camera behind the camera lens 13 has a resolution sufficient to enable the control unit to recognize a face. In the simplest embodiment of the present invention, the device 1 is designed solely to recognize a face as such in order to exclude it from irradiation, or to suspend irradiation if a face is in the irradiation area.

[0058] For the LED in this example, it is crucial that a peak of the emitted wavelength spectrum lies between 280 nm and 315 nm. In this example, an LED with a peak of 298 nm was used. Such LEDs are available from, among others, Dowa Electronic Materials Co., Ltd. (Japan).

[0059] With this design, it was found that a total daily irradiation time of 13 to 14 minutes at a dose of 12.5 mJ / cm 2with an erythemal irradiance of 0.015 mW / cm 2< may be suitable to stimulate and supplement the body's own biosynthesis of vitamin D3 in a user with skin type 2.

[0060] In the Fig. 1b is the device 1 of the Fig. 1a shown again in a frontal view, where only the front panel 11 with the corresponding glass windows 12 and the camera lens 13 are visible from the front. Also clearly visible are the stand 52 and the first gripper 50.1 formed on the base 41. The Fig. 1b serves to define the cutting planes which are shown in detail in the figures discussed below, where a longitudinal cross-section CC and two profile cross-sections AA and BB are shown in detail.

[0061] The Fig. 1c shows the mentioned longitudinal cross-section CC of the Fig. 1bin plan view, i.e. from above onto the device 1. The cross-section CC runs through the center of the vertical extent of the device 1 and thus through the center of the camera and the lens 13, which in the present case are accommodated in the camera compartment of the housing 10. The camera compartment 25 is closed off by a camera lens 26, which is flush with the front side of the front panel 11. A standard camera suitable for capturing an optical image of the surroundings can be placed in the camera compartment 25. The resolution of the camera should be selected such that it can be evaluated by a control unit and face recognition is possible. The camera lens 26 can be selected such that it captures a wide angle, e.g. by having a corresponding curvature or grinding in the lens enlarge the captured area.Such cameras are particularly common in the surveillance sector and can be selected by a person skilled in the art, taking the installation size into account if necessary. The camera forms the sensor unit of the device according to the invention. On both sides of the camera chamber 25 there is a lamp chamber 23 in which two lamps are housed. The lamps comprise a plurality of UV LEDs and are designed to be movable. Overall, the entire lamp chamber is designed as a movement space for the LEDs. The LEDs are attached to an array and are pivoted via a pivot arm 22, which makes the array 17 pivotable at an angle of between ± 45° perpendicular to the plane of the paper. The pivot arm 22 is connected to a lamp carriage 18, which is mounted so as to be horizontally displaceable in a corresponding groove in the lamp frame. For movement, a simple toothed mechanism with a belt drive can be provided, for example.

[0062] The camera (not shown) and the two lamps are mounted on a frame plate 24, which can additionally include the electronic supply lines (not shown in detail). In addition, the frame plate 24 can include the control system. The frame plate 24 can function essentially or from individual parts as a heat exchanger and dissipate any waste heat generated by the lamps to the housing and corresponding heat exchanger elements formed on the housing, such as ventilation slots and / or slats. The base 41 is also visible in the top view. During operation, the lamps would each operate synchronously with one another or independently of one another, e.g. to focus on a specific area. In principle, the lamps additionally comprise reflectors or the glass windows 12 are designed with corresponding lenses in order to essentially collect the light radiation through the lamps, so that the most defined irradiation areas possible are created.The device can be designed to determine, based on the camera image, whether a person is at a suitable distance from the device in order to decide on irradiation.

[0063] The exemplary device is preferably placed in a bathroom area, where, for example, exposed skin areas are more likely than radiation areas. A suitable mounting location is, for example, above the bathroom mirror. Reliable facial recognition prevents harmful UV-B radiation from being directed at the eyes despite this location.

[0064] The Fig. 1d shows the device in side view, with the housing 10 being closed off at the front by the front panel 11, and the resulting housing combination being connected to a base 41 via a stand 52. The two grippers 50.1, 50.2 enclose a retaining groove 51.

[0065] In a particular embodiment, the grippers 50.1, 50.2 are made of a flexible, elastic material so that they exert a restoring force on an object in the holding groove 51.

[0066] The Fig. 1e shows the cross-section through the center of the device in plane AA. In addition or as an alternative to the Fig. 1d In contrast to the holder shown, which has flexible grippers 50.1, 50.2, this embodiment has a magnet 53, which additionally enables the device 1 to be secured to a metallic and / or magnetic holding element within the holding groove 51. The entire holder is connected to the housing 10 via a ball joint 55. A frame plate 24 is provided in the housing 10, which carries a chamber area for a camera chamber 25 in the center, which is closed off at the front by a camera lens 26. The front side is also closed off by the front plate 11.

[0067] In the Fig. 1f isa corresponding cross-section through the axis BB, in which the lamps are housed, is shown. The stand 42 is shown here in a side view. The lamps are located in a lamp compartment 23. If necessary, small mini fans can be provided to supply the lamp compartment 23 with an air flow. These mini fans can carry the waste heat from the lamp compartment 23 to the outside via corresponding ventilation slots in the housing 10 and, for example, cool the lamp during intensive use (not shown). Mounted on the frame plate is a lamp frame 19, which has a rail in which an array 17 with several UV LEDs 21, movable perpendicular to the cutting plane, is mounted. Behind the lamp frame 19, between the lamp frame 19 and the frame plate 24, is a control compartment 27.The control room houses the cable guides for the power supply of the lamp carriage, the swivel arm 22, the lamps and any additional electronics.

[0068] In the Fig. 1g is the device of Fig. 1ashown in an exploded view to clearly define the individual elements. A front panel 11 closes off the device at the front and has several recesses 12, 13. A central recess 13 serves to accommodate a camera lens, or rather enables a camera 20 to take an image of the area in front of the device 1. Two glass windows 12 which are permeable to UV-B radiation are provided on either side of the camera lens 13. A carrier plate 14 defines a lamp compartment 23 through two carrier plate recesses 16 and is located directly behind the glass windows 12 in a front for rear viewing. Two lamps, comprising LED 21, array 17 and lamp carriage 18, are arranged on either side of a camera 20 and are housed in a lamp frame 19. The lamp frame 19 is attached to a frame plate 24.The components are housed in a housing 10, which is connected to a base via a ball joint, which is connected via two grippers 50.1, 50.2. A communication element, or rather a power supply, is led from the housing 10 from the inside of the device to the outside via a cable connection 38 with a USB / power connector 39.

[0069] The Fig. 1hshows in detail the arrangement of a light source in an irradiation chamber 23. The light source comprises a plurality of LEDs 21, which are designed to emit UV-B radiation. The UVBs mentioned preferably have a peak in a range between 290 and 298 nm. The LEDs are attached to an array 17, which can pivot through an angle of between ± 45° via a pivoting arm 22. The pivoting arm 22 is mounted on a light source carriage, which in turn is movably mounted in a light source frame 19. The electronics of the device according to the invention are designed to move the pivoting arm and the light source carriage independently, so that a wide spectrum of irradiation ranges can be covered.

[0070] In the Fig. 1hNot shown are individual reflectors, whereby each LED has a reflector so that the total radiation from the lamp can specifically capture and define a specific irradiation area.

[0071] An alternative to the Fig. 1h The construction shown is in the Fig. 1i Also in the Fig. 1i the lamps extend into the lamp compartment 23. In contrast to the Fig. 1hThe individual LEDs 21 are connected to a lamp body, which can be pivoted on two axes by means of a drive bar 31 and a rear bar 32. A drive bar motor 33 moves the drive bar back and forth in the direction indicated by the arrow, while the rear bar is also moved accordingly. This allows the lamp bodies to be aligned. If such an arrangement is also provided in the horizontal direction with a corresponding drive bar and a corresponding drive bar motor, the LEDs can thus be pivoted such that a wide cone of them can be captured by a light beam.

[0072] In the Fig. 2 An alternative embodiment of the device is shown. Essentially, the device comprises the Fig. 2 the same structure as in device 1, but the device of the Fig. 2Additional illuminants, namely an additional second illuminant and an additional third illuminant. For this purpose, glass panes are provided: a first glass pane for the second illuminant (14) and a second glass pane for the third illuminant (15). These are provided as a recess in a front panel, which, as shown in the Fig. 1 additionally a camera lens 13, as well as a glass window 12 with a lamp behind it, analogous to that shown in the Fig. 1This illuminant is a UV LED diode 21 on an array 17, which is arranged movably, namely via a rail which can be moved by a illuminant carriage 18 on a illuminant frame 19. The device can be connected to a power supply or a computer by means of a USB / power plug 39, thus enabling data exchange. As already described in the general part, a device according to the invention can of course also comprise a module for wireless communication, such as a WiFi or Bluetooth module. Depending on the design, more or less of the control can take place directly in the device according to the invention. Thus, the device can comprise a processor which performs the control tasks as described in the general part and the execution of the computer program product. It is also conceivable that a third-party computer, e.g.a computer connected via the USB port takes over this work.

[0073] Back to the example of Fig. 2 , where in addition to the UV-B light source, a second light source with visible light is provided, and a third light source with light in the near-infrared range, which is not visible but can improve blood circulation in the irradiated tissue. The light in the visible spectrum can, in addition to a positive psychosomatic effect, e.g. by emitting light in a pleasant light color, also indicate the operation of the device. Preferably, this first and second light source are also LED light sources, which have a peak or a spectrum in the wavelength ranges 380 nm to 720 nm for the second light source, and 720 nm and 1,800 nm for the third light source.

[0074] Another alternative embodiment is shown in the Fig. 3ashown. In this embodiment of the present invention, the illuminant is physically coupled to the sensor unit, so that a directing unit moves both synchronously. In other words, the illuminant is always aligned with the camera area. For this purpose, the device according to the invention has a two-part housing 10.1, 10.2. The first part of the two-part housing 10.1 houses the sensor unit, in the present example a camera with a camera lens 13. The second part of the two-part housing 10.2, meanwhile, houses the illuminant behind a glass window 12. A connection 45 between the first part of the two-part housing 10.1 and the second part of the two-part housing 10.2 is rigid and allows both elements to be moved simultaneously by means of a directing unit. In this embodiment, the directing unit comprises a rotatably mounted tool arm 44 and a rotatably mounted stand base 43.A stand extends between them. This allows the device according to the invention to be aligned in a hemispherical area around a base 41, so that a very wide effective area can be covered by a lighting element 29 and a camera element 28.

[0075] This version also draws its power from a USB / power plug 39.

[0076] The device according to the invention is equipped with a control unit. In all of the examples mentioned, the control unit is designed to identify the irradiation area. The corresponding sensor units, i.e., the camera elements in the examples shown, detect an irradiation area and send an image to the control unit. This is designed to identify an irradiation area, i.e., to evaluate the detected irradiation area and determine whether this irradiation area is potentially an irradiation area excluded from irradiation. Whether an irradiation area is excluded from irradiation can be determined using a predefined database, which is stored, for example, in a storage unit (not shown in the figures).It is also conceivable that the computer program product which assumes control is able to determine, by means of intelligent programming based on predefined parameters, whether the irradiation area is such an excluded irradiation area. For this purpose, certain parameters can be provided, such as the shape and arrangement of recognizable patterns in the captured image area and the assignment of these recognizable patterns to certain elements in a system for an irradiation area which is excluded from irradiation. Typically, these are elements which are used for facial recognition, such as the position and distance of the eyes, nose and mouth for the recognition of a human face. It is also conceivable that the device shown can be connected to a machine learning-supported program.The computer program product would compare the detected irradiation areas with a database and, using machine learning, determine whether these irradiation areas are potentially excluded irradiation areas. In addition, the computer program product is capable of controlling the irradiation as a whole. This can be achieved, for example, by designing the computer program product to assign the duration of an irradiation to a specific irradiation area. This ensures that the irradiation area is not exposed to the same radiation intensity twice.

[0077] It goes without saying that the device according to the invention requires a control unit which is designed to operate the said computer program product and which is capable of executing the corresponding instructions. For this purpose, the control unit can provide a corresponding processor, as well as optionally further elements, such as a computer memory, a working memory and / or an output unit. The output unit can be, for example, a simple display. The display can facilitate the initial setup of the device according to the invention. These elements can be outsourced in whole or in part to a third-party device, i.e., they do not necessarily have to be located within the housing of the device described above. The computer program product can also be designed to synchronize a plurality of devices according to the invention with one another. For example, the computer program product canbe designed to network a plurality of devices arranged in a specific area, such as a building. This can go so far that facial recognition, which can assign the face to a specific person, can ensure that the person within a building is exposed to the appropriate dose of light radiation while still ensuring the appropriate safety measures, such as ensuring that a specific area of ​​skin can never be used as an irradiation area twice.

[0078] Ideally, a device as shown in this invention can be used in private areas. However, the device is particularly suitable in areas where, for example, skin exposure is greater than in public spaces where more clothing tends to be worn. For example, bathing establishments, swimming pools, wellness areas, private bathrooms, or changing rooms are ideal areas in which a device according to the invention, as described here, can be placed. The teaching of the present invention makes it possible to make the stimulation of vitamin D3 biosynthesis a casual process, which enables good compliance by the user. Thus, there is no longer any need to take vitamin D3 supplements, which can sometimes be forgotten, or to plan certain rigorous outdoor activities. Suitable applications, in addition to the notorious latitudes, include, for example:Areas where, due to the conditions, little natural sunlight shines in during the day, e.g. in underground facilities, large warehouse and factory complexes, open-plan offices, offshore installations, as well as the interior of buildings in narrow and poorly lit side and mountain valleys. List of reference symbols

[0079] 1)Device for stimulating the biosynthesis of vitamin D3 10)Housing 10.1)First part: two-part housing 10.2)Second part: two-part housing 11)Front panel 12)Glass window 13)Camera lens 14)Glass pane for second illuminant 15)Glass pane for third illuminant 16)Support plate recesses 17)Array 18)Illuminant carriage 19)Illuminant frame 20)Camera 21)UV LED diode 22)Swivel arm 23)Illuminant compartment 24)Frame plate (heat exchanger) 25)Camera compartment 26)Camera lens 27)Control compartment 28)Camera element 29)Illuminant element 30)Illuminant body 31)Drive bar 32)Rear bar 33)Drive bar motor 34)Swivel joint 38)Cable connection 39)USB / power plug 41)Stand 42)Stand 43)Rotatable stand base 44)Rotatable tool arm 45)Connection 50.1)First gripper 50.2)Second gripper 51)Holding groove 52)Stand 53)Magnet 55)Ball joint

Claims

1. A device (1) for stimulating the biosynthesis of vitamin D3, comprising: a. at least one first lighting means (21) for emitting light radiation having wavelengths in a range of between 280 and 315 nm; c. a directing unit for aligning the at least one lighting means with the irradiation region, and d. a control unit, which is configured to trigger emission of light radiation having wavelengths in a range of between 280 and 315 nm by the at least one lighting means, characterized by b. a sensor unit for detecting an irradiation region; wherein the control unit is further configured to identify the irradiation region.

2. The device according to claim 1, wherein the sensor unit comprises an optical sensor, in particular a camera.

3. The device according to any of claims 1 or 2, wherein the control unit is configured to control an alignment of the first lighting means by means of the directing unit based on an identified irradiation region.

4. The device according to any of claims 1 to 3, comprising a collecting unit for generating a directed beam of rays from the emission of light radiation by the first lighting means.

5. The device according to claim 4, wherein the collecting unit comprises a lens and / or a collimator, in particular a collimator comprising a collecting lens for generating a directed bundle of rays from the emission of light radiation by the first lighting means.

6. The device according to any of claims 1 to 5, comprising a second lighting means for emitting light radiation having wavelengths in the visible range, in particular having wavelengths in a range of between 380 nm and 720 nm.

7. The device according to any of claims 1 to 6, comprising a third lighting means for emitting light radiation having wavelengths in the near infrared range, in particular in a range of between 720 nm and 1800 nm.

8. The device according to any of claims 1 to 7, wherein the control unit is configured to identify a human face in an irradiation region.

9. The device according to any of claims 1 to 8, wherein the control unit is configured to identify a predefined irradiation region.

10. The device according to any of claims 1 to 9, comprising a communication unit for exchanging data.

11. The device according to any of claims 1 to 10, wherein the first lighting means and / or the second lighting means and / or the third lighting means and the sensor unit are physically coupled such that they can be jointly directed at the irradiation region by the directing unit.

12. The device according to any of claims 1-11, wherein the directing unit is configured to be pivotable in at least two axes, in particular by at least a rotatably mounted stand base and a rotatably mounted tool arm for pivoting a lighting means on at least two axes.

13. The device according to any of claims 1 to 12, wherein the irradiation region is a skin region having an area of between 40 cm2 and 900 cm2, in particular of between 50 cm2 and 600 cm2, in particular of approximately 400 cm2.

14. The device according to claim 13, wherein the skin region is definable by an adjustable collecting unit.

15. A computer program product for executing control of a device comprising a sensor unit and a first lighting means for stimulating the biosynthesis of vitamin D3, in particular a device according to any of claims 1 to 13, wherein a. the computer program product is configured to compare an irradiation region detected by said sensor unit with predefined irradiation regions, and b. the computer program product is configured to trigger emission of light radiation having wavelengths in a range of between 280 nm and 315 nm by at least said lighting means if the detected irradiation region does not correspond to an irradiation region excluded from irradiation.

16. The computer program product according to claim 15, wherein an irradiation region excluded from irradiation is an irradiation region selected from the group consisting of: a human face, a skin region provided with one or more pigmented nevi, a skin region provided with scab, wound, and / or scar tissue, and a skin region already irradiated within a predefined time interval with light radiation having wavelengths in a range of between 280 nm and 315 nm.

17. The computer program product according to any of claims 15 or 16, wherein the computer program product is configured to assign a time interval to a specific irradiation region in which the irradiation region is to be irradiated with light radiation having wavelengths in a range of between 280 nm and 315 nm.

18. The computer program product according to any of claims 15 to 17, wherein the computer program product is configured to control a search of a predefined irradiation region by the computer program product controlling the sensor unit.

19. The computer program product according to any of claims 15 to 18, wherein the computer program product is configured to compare each image captured by an optical sensor with an irradiation region excluded from irradiation.

20. The computer program product according to any of claims 15 to 19, wherein the computer program product is configured to enter an operating mode by means of a signal from the sensor unit, in particular to search for a suitable irradiation region that is not excluded from irradiation.

21. The computer program product according to any of claims 15 to 20, wherein the computer program product causes exposure of an irradiation region to light radiation having wavelengths in a range of between 280 nm and 315 nm as soon as a sensor unit detects an irradiation region excluded from irradiation in the effective range of the lighting means.

22. The computer program product according to any of claims 15 to 21, which is further configured to monitor or configure the execution of control of a device for stimulating the biosynthesis of vitamin D3 on a third-party apparatus by means of a communication unit.

23. The computer program product, which can be executed on a third-party apparatus and is configured to manage user data for a device according to any of claims 1 to 14, a. wherein the user data contains data selected from the group consisting of: skin type, age, profession, and lifestyle, and b. wherein the computer program product is configured to exchange said user data in encrypted form with a communication unit of the device.