Method for estimating blood pressure of wearer of compression therapeutic garment

Abstract

To provide a system and a method for specifying a blood pressure and / or a pulse rate of a wearer of a compression garment.SOLUTION: A vital parameter of a wearer of a compression garment is monitored by analyzing a pressure signal waveform indicating a fluid pressure in the inside of a bladder capable of expansion and contraction of the compression garment. Display of blood pressure of the wearer is provided by analyzing the pressure signal waveform of amplitude of vibration as a function of time and / or as display of a pulse rate of the wearer.SELECTED DRAWING: Figure 1

Description

Technical Field

[0001] The present disclosure relates to a system and method for identifying the blood pressure and / or heart rate of a compression garment wearer .

Background Art

[0002] Cross-reference to Related Applications This application claims priority to U.S. Provisional Patent Application No. 62 / 527,155, filed Jun. 30, 2017 , the disclosure of which is hereby incorporated by reference in its entirety, including the contents and teachings of the references contained therein .

[0003] Intermittent pneumatic compression (IPC) systems include devices used to apply a pressurized fluid, such as air, to a patient's or wearer's limbs . In some cases, pressurized air is applied to the lower limbs of patients at risk of forming blood clots (thrombi) associated with deep vein thrombosis (DVT) . An IPC system typically includes a pump unit that manages the pressurization of the fluid, a tubing set that extends the delivery of the fluid beyond the pump unit, and a compression garment that wraps around the patient's limb and contains the pressurized fluid . The IPC system intermittently pressurizes the garment to apply therapeutic compression to the patient's limb and move blood away from that area of the limb . Many IPC systems utilize pressure sensors as the only means of feedback . The output of the pressure sensor is used to adjust the fluid delivery to the compression garment and maintain a predetermined pressure, but the measurable pressure is limited to the pressure within the compression garment and the tubing .

Summary of the Invention

Means for Solving the Problems

[0004] ​​​In one embodiment, a small amount of the garment is provided to provide compression therapy treatment to the wearer of the garment. The controller for controlling the inflation and deflation of at least one bladder includes a memory and a The non-transitory computer-readable storage medium includes the above processor. The computer readable storage medium may be configured to transmit to the one or more processors at least one of a pressure sensor and a pressure sensor for detecting at least one of the pressure sensors. and receiving a signal indicative of fluid pressure in another bladder, the received signal fluctuating as a function of time. The non-transitory computer includes computer executable instructions for determining whether the non-transitory computer includes a motion amplitude. The computer readable storage medium also includes a step of determining whether the received signal includes a vibration amplitude as a function of time. and transmitting to the one or more processors a blood sample of the wearer of the garment based at least in part on the determination of The method includes computer executable instructions for estimating pressure.

[0005] In another embodiment, the system comprises a pressure device including at least one inflatable and deflatable bladder. The system includes a compression garment, the compression garment being capable of being secured around a limb of a wearer. at least one portion of the garment is provided to provide compression therapy treatment to the wearer of the garment The device further includes a controller for controlling the inflation and deflation of the bladder. a memory, one or more processors, and a pressure sensor for detecting a pressure of the garment from the one or more processors; Receiving a signal indicative of fluid pressure within at least one bladder, the received signal being a function of time. a non-transitory computer readable medium comprising instructions for determining whether the vibration amplitude is included as The non-transitory computer-readable storage medium also includes a storage medium in which the received signal is stored. Based at least in part on the determination of whether the function includes vibration amplitude, one or more processes are Including computer-executable instructions for causing a sensor to estimate the blood pressure of a garment wearer .

[0006] In another aspect, a controller for controlling the inflation and deflation of at least one bladder of a garment to provide compressive therapy to a garment wearer includes a memory, one or more processors, and a non-transitory computer-readable storage medium. The non-transitory com puter-readable storage medium includes computer-executable instructions for causing one or more processors to receive a signal indicative of the fluid pressure within at least one bladder of the garment from a pressure sensor and to determine whether the received signal includes an indication of the wearer's pulse. The non-transitory com puter-readable storage medium also includes computer-executable instructions for causing one or more processors to determine the blood pressure of the garment wearer based at least in part on a determination of whether the received signal includes a signal indicative of the wearer's pulse.

[0007] In another aspect, a system includes a compression garment including at least one inflatable and deflatable bladder, the compression garment being securable around a limb of a wearer. The system further includes a controller for controlling the inflation and deflation of at least one bladder of the garment to provide compressive therapy to the garment wearer. The controller includes a me mory, one or more processors, and a non-transitory computer-readable storage medium including instructions for causing one or more processors to receive a signal indicative of the fluid pressure within at least one bladder of the garment from a pressure sensor and to determine whether the received signal includes an indication of the wearer's pulse. The non-transitory computer-readable storage medium also includes computer-executable instructions for causing one or more processors to determine the blood pressure of the garment wearer based at least in part on a determination of whether the received signal includes a signal indicative of the wearer's pulse. ​​​​​​​​​One or more processors based at least in part on a determination of whether a signal indicating a beat is included includes computer-executable instructions for causing a garment wearer's blood pressure to be identified.

[0008] Embodiments can include one or more of the following advantages.

[0009] In some embodiments, identification of the wearer's blood pressure is performed using a signal indicating the pressure within an inflatable bladder of a compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurement, a more accurate display of patient compliance with a treatment protocol, and / or can reduce the burden on a caregiver with respect to monitoring of a patient's vital parameters. Compared to monitoring of a wearer's vital parameters while the wearer is undergoing treatment, the display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort. parameters.

[0010] Other aspects, features, and advantages will be apparent from the description and drawings, and from the claims. BRIEF DESCRIPTION OF THE DRAWINGS

[0011]

Figure 1

[0012]

Figure 2

[0013] ​​​​​​

Figure 3

[0014]

Figure 4A

Figure 4B

Figure 4C

Figure 4D

[0015]

Figure 5

[0016] As used herein, the terms "proximal" and "distal" refer to the relative positions of components, parts, etc. of the compression garment when the garment is worn. For example, a "proximal" component is disposed closest to the wearer's torso, a "distal" component is disposed farthest from the wearer's torso, and an "intermediate" component is generally disposed anywhere between the proximal and distal components. Further, as used herein, the terms "wrapped" and "not wrapped" refer to the state of the garment around the wearer's limbs. when it is wrapped or not wrapped around the wearer's limbs. when it is wrapped or not wrapped around the wearer's limbs. Define the state of the garment where the ment is properly attached to the wearer's hands and feet (e.g., wrapped, worn, etc.), and define the state of the garment where the garment is removed from the wearer's hands and feet (e.g., not wrapped, not worn, etc.). Define the state of the garment where the ment is properly attached to the wearer's hands and feet (e.g., wrapped, worn, etc.), and define the state of the garment where the garment is removed from the wearer's hands and feet (e.g., not wrapped, not worn, etc.). Define the state of the garment where the ment is properly attached to the wearer's hands and feet (e.g., wrapped, worn, etc.), and define the state of the garment where the garment is removed from the wearer's hands and feet (e.g., not wrapped, not worn, etc.). Define the state of the garment where the ment is properly attached to the wearer's hands and feet (e.g., wrapped, worn, etc.), and define the state of the garment where the garment is removed from the wearer's hands and feet (e.g., not wrapped, not worn, etc.).

[0017] Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein. Aspects of the disclosure herein are related to U.S. Patent Application No. 15 / 290,026, filed on October 11, 2016, PCT Application No. PCT / US2016 / 056296, filed on October 10, 2016, and applications claiming priority, namely, all U.S. Provisional Patent Applications No. 62 / 239,527, No. 62 / 239,493, and No. 62 / 239,566, filed on October 9, 2015, and U.S. Provisional Patent Application No. 62 / 329,233, filed on April 29, 2016. The entire contents of the applications specified above are hereby expressly incorporated herein by reference, including the contents and teachings of the references contained therein.

[0018] Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments Referring to FIGS. 1 and 2, the compression system 1 includes a compression garment 10 for performing continuous compression therapy on the wearer's hands and feet, and a controller 5 having computer-executable instructions embodied on one or more processors 7 and a non-transitory computer-readable storage medium (e.g., memory) 33. The computer-executable instructions include instructions for causing one or more processors 7 to control the operation of the compression system 1. The compression garment 10 includes a distal inflatable bladder 13a, an intermediate inflatable bladder 13b, and a proximal inflatable bladder 13c. The compression garment 10 can be fixed around the wearer's hands and feet, and in some embodiments , adjustable to fit different surrounding limbs. Inflatable bladders 13a, 13b, 13c, in some embodiments, at least partially extend around a portion of the wearer's limb. For example, the inflatable bladders 13a, 13b, 13c can be hip-specific bladders .

[0019] As will be described in more detail below, the controller 5, based at least in part on the measured pressure of one or more of the inflatable bladders 13a, 13 b, 13c, determines the blood pressure and / or heart rate of the wearer around whose limb the compression garment 10 is attached (i.e., in a wrapped-around configuration) and, in some embodiments, correlates the blood pressure to arterial blood pressure and provides an indication of the determined blood pressure and / or correlated arterial blood pressure (e.g., by providing an audible alarm and / or providing a visual display on a graphical user interface). In additional or alternative embodiments, the controller 5 determines the respiratory rate of the wearer, changes in peripheral resistance (e.g., due to vasodilators / vasoconstrictors, etc.), and / or the movement of the wearer (e.g., monitoring the movement of a patient) based at least in part on the measured pressure of one or more of the inflatable bladders 13a, 13b, 13c. As will be described in more detail below, the controller 5 can control the operation of the compression system 1 to perform inflation cycles, during which the inflatable bladders 13a, 13b, 13c inflate to apply pressure to the wearer's limb and, for example, establish the distribution pressure applied to the wearer's limb by the inflatable bladders 13a, 13b, 13c of the compression garment 10 during one or more compression cycles. As will be described in more detail below, each therapeutic compression cycle is a bladder Based at least in part on the measured pressure of one or more of 13a, 13b, 13c, The respiratory rate of the wearer, changes in peripheral resistance (e.g., due to vasodilators / vasoconstrictors, etc.), and / or the movement of the wearer (e.g., monitoring the movement of the patient) are determined. As will be described in more detail below, the controller 5 controls the operation of the compression system 1 to perform inflation cycles, during which the inflatable bladders 13a, 13b, 13c inflate to apply pressure to the wearer's limb and, for example, establish the distribution pressure applied to the wearer's limb by the inflatable bladders 13a, 13b, 13c of the compression garment 10 during one or more compression cycles. As will be described in more detail below, each therapeutic compression cycle is a bladder can perform inflation cycles, during which the inflatable bladders 13a, 13b, 13c inflate to apply pressure to the wearer's limb, and, for example, establish the distribution pressure applied to the wearer's limb by the inflatable bladders 13a, 13b, 13c of the compression garment 10 during one or more compression cycles. As will be described in more detail below, each therapeutic compression cycle is a bladder Establish the distribution pressure applied to the wearer's limb by the inflatable bladders 13a, 13b, 13c of the compression garment 10. As will be described in more detail below, each therapeutic compression cycle Each inflation stage of bladders 13a, 13b, 13c, and each of bladders 13a and 13b including a decay stage, and each decompression or ventilation stage of bladders 13a, 13b, 13c can be achieved. The end pressure of each cycle of each bladder 13a, 13b, 13c is the pressure within each bladder 13a, 13b, 13c before the start of the decompression stage of each bladder 13a, 13b, 13c .

[0020] The compression garment 10 is a sleeve of a length up to the thigh that can be arranged around the leg of the wearer , with the distal bladder 13a around the wearer's ankle, the intermediate bladder 13b around the wearer's calf , and the proximal bladder 13c around the wearer's thigh. The inflatable bladders 13a, 13b, 13c are affected by fluid (e.g., air or other fluid) delivered from a pressurized fluid source 21 (e.g., a pump or compressor) that is in electrical communication with the controller 5 and expand and contract. The pressurized fluid source 21 delivers pressurized fluid (e.g., air) to the inflatable bladders 13a, 13b, 13c through a tube 23 .

[0021] Referring to FIG. 2, each inflatable bladder 13a, 13b, 13c is in fluid communication with respective valves 25a , 25b, 25c. The pressure sensor 27 communicates (e.g ., fluid communication and / or mechanical communication) with the manifold 29 and measures a signal indicating the pressure within the manifold 29 . The fluid communication between the manifold 29 and each inflatable bladder 13a, 13b, 13c can be controlled by controlling the position of respective valves 25a, 25b, 25c (e.g ., by actuation and / or non - actuation of respective valves 25a, 25b, 25c). The pressure sensor 27 is such that the processor 7 receives from the pressure sensor 27 the manifold 29 and / or it from the pressure sensor 27, the manifold 29 and / or it As a result of the positions of the respective valves 25a, 25b, 25c, fluid communication with the manifold 29 to receive a signal indicating the pressure of one or more inflatable bladders 13a, 13b, 13c that are electrically communicates with the processor 7. Only one bladder 13a, 13b, or 13c is in fluid communication with the manifold 29, the signal received from the pressure sensor 27 indicates the pressure of each bladder 13a, 13b, 13c that is in fluid communication with the manifold 29. For example, the pressure sensor 27 provides a signal indicating the pressure within the inflatable bladder 13a when the valve 25a is open and the valves 25b, 25c are closed. Similarly, the pressure sensor 27 provides a signal indicating the pressure within the bladder 13b when the valve 25b is open and the valves 25a and 25c are closed. Similarly, the pressure sensor 27 provides a signal indicating the pressure within the bladder 13c when the valve 25c is open and the valves 25a and 25b are closed. The vent valve 25d is operable to control the fluid communication between the manifold 29 and a vent port that vents to the ambient atmosphere. All bladders 13a, 13b, 1 3c can be vented using the vent valve 25d.

[0022] Each valve 25a, 25b, 25c is a two-way / two-position normally open solenoid valve. Each valve 25a , 25b, 25c includes two ports and is operable to fluidly communicate the inlet port with the bladder port in a first open position. Each valve 25a, 25b, 25c is further operable to block the fluid communication between the inlet port and the bladder port. The inlet ports of each valve 25a , 25b, 25c are in fluid communication with the pressurized fluid source 21 and the manifold 29. The bladder ports of each valve 25a, 25b, 25c are in fluid communication with the respective inflatable bladders 13a , 25b, 25c respectively. is in fluid communication with 13b and 13c.

[0023] Any one of the bladders 13a, 13b, 13c is arranged in fluid communication with a pressurized fluid source 21 and a manifold 29 by respective valves 25a, 25b, 25 c, and can deliver pressurized fluid to the bladders 13a , 13b, 13c. After the bladders 13a, 13b, 13c are inflated, the respective valves 25a, 25b, 25c can be closed to hold the fluid within the respective bladders 13a, 13b, 13c. Thus, the bladders 13a, 13b, 13c of the compression garment 10 can be individually inflated by opening the respective valves 25a, 25b, 25c associated with one of the bladders 13a, 13b, 13c and closing the other valves 25a, 25b, 2 5c so that only one of the bladders 13a, 13b, 13c is in fluid communication with the pressurized fluid source 21 and the manifold 29. 5c.

[0024] The vent valve 25d is also a two-way / two-position normally open solenoid valve. The vent valve 25d includes two ports and is operable to fluidly communicate an inlet port with a vent port in a first position . The vent inlet port is in fluid communication with the vent port in the first position. The vent valve 2 5d is further operable to block fluid communication between the inlet port and the vent port . The inlet port of the vent valve 25d is in fluid communication with the pressurized fluid source 21 and the manifold 29 . The vent port of the vent valve 25d is in fluid communication with the ambient atmosphere.

[0025] Of course, the valves 25a, 25b, 25c, 25d of FIG. 2 can be of other types and have other arrangements within the compression system 1 without departing from the scope of the present disclosure. It is possible. For example, referring to FIG. 3, the valve is a 3-way / 2-position solenoid valve and is operable to control the pressure in the bladders 13a, 13b, 13c without a vent valve. The valves 35a, 35b, 35c can be used. Referring back to FIG. 2, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can include instructions for causing one or more processors 7 to pressurize (e.g., inflate) the inflatable bladders 13a, 13b, 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. For example, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can cause one or more processors 7 to control the pressurized fluid source 21 and / or the valves 25a, 25b, 25c, 25d to pressurize the inflatable bladders 13a, 13b, 13c to a therapeutic compression pressure for a predetermined time to move blood in the limbs from the area under the inflatable bladders 13a, 13b, 13c. For example, one or more processors 7 can use the timing signal and / or timing data provided by the timer 31 to measure the time the inflatable bladders 13a, 13b, 13c are pressurized. According to one or more embodiments, the timer 31 can be configured with a clock, one or more timer circuits (e.g., a 555 timer integrated circuit, etc.), computer-executable instructions including a timing routine, and / or other timers well known to those skilled in the art. The time the bladders 13a, 13b, 13c are held at the compression pressure is referred to herein as the decay phase. Following the decay phase is the decompression phase. The computer-executable instructions can cause one or more processors 7 to control the pressurized fluid source 21 and / or the valves 25a, 25b, 25c, 25d. 35a, 35b, 35c.

[0026] Referring back to FIG. 2, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can include instructions for causing one or more processors 7 to pressurize (e.g., inflate) the inflatable bladders 13a, 13b, 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. Referring back to FIG. 2, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can include instructions for causing one or more processors 7 to pressurize (e.g., inflate) the inflatable bladders 13a, 13b, 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. For example, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can include instructions for causing one or more processors 7 to pressurize (e.g., inflate) the inflatable bladders 13a, 13b, 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. Referring back to FIG. 2, the computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 can include instructions for causing one or more processors 7 to pressurize (e.g., inflate) the inflatable bladders 13a, 13b, 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. 13c to a therapeutic compression pressure for a predetermined time to move blood in the limbs from the area under the inflatable bladders 13a, 13b, 13c. 13c. For example, one or more processors 7 can use the timing signal and / or timing data provided by the timer 31 to measure the time the inflatable bladders 13a, 13b, 13c are pressurized. 13c are pressurized. 13c are pressurized. According to one or more embodiments, the timer 31 can be configured with a clock, one or more timer circuits (e.g., a 555 timer integrated circuit, etc.), computer-executable instructions including a timing routine, and / or other timers well known to those skilled in the art. For example, a 555 timer integrated circuit, etc.), computer-executable instructions including a timing routine, and / or other timers well known to those skilled in the art. 13c are held at the compression pressure is referred to herein as the decay phase. 13c are held at the compression pressure is referred to herein as the decay phase. Following the decay phase is the decompression phase. The computer-executable instructions can cause one or more processors 7 to control the pressurized fluid source 21 and / or the valves 25a, 25b, 25c, 25d. 13c to provide periodic therapeutic compression pressure to the limbs of the wearer. and includes an instruction to reduce the pressure within the inflatable bladders 13a, 13b, 13c to a lower pressure (e.g., atmospheric pressure).

[0027] The compression system 1 can identify changes in the wearer's blood pressure, heart rate, respiratory rate, peripheral resistance, and / or movement around their limbs (i.e., in a wrapped configuration), and in certain embodiments, can provide that specific indication, which can, for example, facilitate monitoring of the wearer's vital parameters with the compression garment 10, tracking the wearer's compliance with the prescribed therapeutic use of the compression garment 10. For example, monitoring the vital parameters with the compression garment 10 reduces the adverse effect on the wearer's comfort caused by using, in addition to the compression garment 10, a blood pressure monitor or the like. Also, monitoring the vital parameters with the compression garment 10 reduces the need for medical personnel (e.g., nurses) to monitor multiple medical devices and reduces the potential for information gaps and errors. Computer-executable instructions embodied on a non-transitory computer-readable storage medium 33 include instructions for causing one or more processors 7 to analyze pressure signal data received from the pressure sensor 27 during a static period of the treatment cycle of the compression system 1. Computer-executable instructions embodied on a non-transitory computer-readable storage medium 33 include instructions for causing one or more processors 7 to detect a waveform peak of the output of the pressure sensor 27 that correlates with the wearer's heart rate range, identify the frequency of the waveform peak, and evaluate the oscillation amplitude for blood pressure estimation. Non-transitory computer-readable ​​​​​​​​​The computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to utilize one or more algorithms based on the magnitude of the vibration amplitude to estimate the blood pressure of a wearer around whose limb the compression garment 10 is worn. The computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to correlate the estimated blood pressure of the wearer based on the magnitude of the vibration amplitude with the corresponding arterial blood pressure of the wearer around whose limb the compression garment 10 is worn. In an exemplary embodiment, the computer-executable instructions cause one or more processors 7 to receive pressure signal data from the pressure sensor 27. The computer-executable instructions can include instructions that cause one or more processors 7 to process a single waveform representative of the pressure within one or more bladders 13a, 13b, 13c. Of course, one or more processors 7 can process multiple waveforms without departing from the scope of the present disclosure. For example, by monitoring the pressure signal and corresponding pressure data during a static period of a treatment cycle, one or more processors 7 can detect specific features on a waveform indicative of the wearer's heart rate. In a particular embodiment, during the static period, the pressure sensor 27 remains in a constant communication (e.g., fluid communication and / or mechanical communication) with one or more bladders 13a, 13b, 13c (or is intentionally placed in a constant communication). Exemplary static periods include non-treatment cycles (e.g., pressure within bladders 13a, 13b, 13c is less than about 25 mmHg), a subset of the initial garment detection period, an extension of the treatment cycle, and / or a venous refill measurement period.

[0028]

[0029] ​​​​​​​​​​​​​​​​​ In the exemplary operation of the embodiment of FIG. 3 in which a 3-way / 2-position valve is utilized, computer-executable instructions embodied on a computer-readable memory medium 33 cause one or more processors 7 to operate one or more valves 35a, 35b, 35c for one or more of the specific bladders 13a, 13b, 13c such that a fluid path is established between the pressure sensor 27 and one or more of the bladders 13a, 13b, 13c. include instructions to activate.

[0030] In the exemplary operation of the embodiment of FIG. 2 in which a 2-way / 2-position valve is utilized, computer-executable instructions embodied on a computer-readable memory medium 33 cause one or more processors 7 to open and close the vent valve 25d such that the manifold 29 can no longer vent. include instructions to cause. One or more computer-executable instructions cause one or more processors 7 to determine whether a signal received from the pressure sensor 27 includes oscillatory characteristics (e.g., a substantially sinusoidal pattern) indicative of the presence of a heartbeat (i.e., a pulse) of the wearer of the compression garment 10. Since a quantity of fluid (e.g., air) is maintained within one or more of the bladders 13a, 13b, 13c and the manifold 29, the pulse of the wearer of the compression garment can generate a signal with oscillatory characteristics carried in the overall pressure waveform. Of course, these oscillatory characteristics can be extracted by signal processing of the overall pressure waveform. from the received signal. characteristics (e.g., substantially sinusoidal pattern) indicative of the presence of a heartbeat (i.e., a pulse) of the wearer of the compression garment 10. A quantity of fluid ( e.g., air) is maintained within one or more of the bladders 13a, 13b, 13c and the manifold 29, so that the pulse of the wearer of the compression garment is carried in the overall pressure waveform with oscillatory characteristics. characteristics that can be generated. Of course, these oscillatory characteristics can be extracted by signal processing of the overall pressure waveform signal.

[0031] Referring to FIG. 4A, signals from the pressure sensor 27 during a typical bladder inflation period 41 and pressure hold period 43, and the pressure profile of one of the bladders 13a, 13b, 13c in the wrapped configuration of the compression garment 10 are shown. In this embodiment, during the pressure hold period of the wrapped configuration of the compression garment 10, the pressure profiles of one of the bladders 13a, 13b, 13c are shown. In this embodiment, during the pressure hold period of the compression garment 10, the pressure profiles of one of the bladders 13a, 13b, 13c are shown. In this embodiment, during the pressure hold period 43 represents one of the bladders 13a, 13b, or 13c that has a duration of about 20 seconds and expands up to about 200 mmHg. In some embodiments, the bladders 13a, 13b, or 13c can expand up to about 160 mmHg or more to detect the wearer's blood pressure. b, or 13c. In some embodiments, the bladders 13a, 13b, or 13c can be expanded up to about 160 mmHg or more to detect the wearer's blood pressure. It is possible.

[0032] Next, referring to FIG. 4B, a typical subset of the received pressure signal during the pressure holding period 43 is shown. For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering). For the purposes of the description herein, the subset portion of the pressure holding period 43 in FIG. 4B is referred to as the target subset signal. Computer-executable instructions embodied on the non-transitory computer-readable storage medium 33 cause one or more processors 7 to receive signals from the pressure sensor 27 indicating the bladder pressure during the bladder inflation period 41 and the pressure holding period 43. The computer-executable instructions can further include instructions for causing one or more processors 7 to refine the signals from the pressure sensor 27 and extract frequencies related to a typical human heart cycle from the signals received during the pressure holding period 43. For example, one or more processors 7 can extract frequencies in the range of 0.5 Hz to 25 Hz (e.g., by band-pass filtering).

[0033] FIG. 4C shows the waveform 43' that is the result of applying band-pass filtering techniques to the target signal of the pressure holding period 43 such that the relevant frequency range (e.g., 0.5 Hz to 25 Hz) is extracted. In some embodiments, the filtered signal 43' clarifies the vibrations related to the wearer's pulse and makes them more visible when the vibrations are displayed by the display device. Additionally or alternatively, one or more processors 7 are related to the wearer's pulse. FIG. 4C shows the waveform 43' that is the result of applying band-pass filtering techniques to the target signal of the pressure holding period 43 such that the relevant frequency range (e.g., 0.5 Hz to 25 Hz) is extracted. In some embodiments, the filtered signal 43' clarifies the vibrations related to the wearer's pulse and makes them more visible when the vibrations are displayed by the display device. Additionally or alternatively, one or more processors 7 are related to the wearer's pulse. FIG. 4C shows the waveform 43' that is the result of applying band-pass filtering techniques to the target signal of the pressure holding period 43 such that the relevant frequency range (e.g., 0.5 Hz to 25 Hz) is extracted. In some embodiments, the filtered signal 43' clarifies the vibrations related to the wearer's pulse and makes them more visible when the vibrations are displayed by the display device. Additionally or alternatively, one or more processors 7 are related to the wearer's pulse. FIG. 4C shows the waveform 43' that is the result of applying band-pass filtering techniques to the target signal of the pressure holding period 43 such that the relevant frequency range (e.g., 0.5 Hz to 25 Hz) is extracted. In some embodiments, the filtered signal 43' clarifies the vibrations related to the wearer's pulse and makes them more visible when the vibrations are displayed by the display device. Additionally or alternatively, one or more processors 7 are related to the wearer's pulse. FIG. 4C shows the waveform 43' that is the result of applying band-pass filtering techniques to the target signal of the pressure holding period 43 such that the relevant frequency range (e.g., 0.5 Hz to 25 Hz) is extracted. In some embodiments, the filtered signal 43' clarifies the vibrations related to the wearer's pulse and makes them more visible when the vibrations are displayed by the display device. Additionally or alternatively, one or more processors 7 are related to the wearer's pulse. Filter the signal 43 to remove non - contiguous frequencies, and the resulting filter The data associated with the filtered signal 43’ is further analyzed by one or more processors 7 as part of peak detection and compliance monitoring algorithms, as will be described in more detail below. Of course, as described herein, one or more processors 7 detect the pulsations related to the wearer's heartbeat rather than the actual heart rate of the wearer of the compression garment 10.

[0034] Referring to FIG. 4D, a sub - set portion of the waveform 43’ showing the band - pass filtered signal of interest (e.g., the partial enlarged view of FIG. 4C) is shown.

[0035] FIG. 5 is a schematic diagram of an exemplary method 500 for identifying the blood pressure and / or pulse rate of a wearer by analyzing the waveform data received from the pressure sensor 27 to detect the pulsations related to the wearer's heartbeat around the hands and feet where the compression garment 10 is worn. This exemplary method can be performed by one or more processors 7 by executing computer - executable instructions embodied on a non - transitory computer - readable storage medium 33. One or more processors 7 execute computer - executable instructions to sample 502 the initial pressure. In some embodiments, the initial pressure sampling is performed at a frequency of 100 Hz or higher, and typical signal conditioning is used to remove baseline noise.

[0036] Additional or alternatively, the sampling 502 may be extended to include attenuation of frequencies just below the low - cut - off (e.g., 0.25 Hz).

[0037] ​​​​​​​​​Post - processing waveform analysis 504 further includes a band - pass filter 506, additional filtering 508, and peak detection 510. During the band - pass filter 506, the signal of interest is filtered using band - pass filtering techniques in a range of typical frequencies related to the typical heart rate range of a human wearer (e.g., 0.5 - 25 Hz for a human wearer).

[0038] During the additional filtering 508, the peaks of the band - pass - filtered signal are further refined. The additional filtering can include a low - pass filter with a cut - off of 5 Hz to generate a filtered value. Additionally or alternatively, the additional filtering can include a smoothing algorithm that uses the latest 5 samples of the moving range to generate a filtered value. Of course, during the additional filtering step 508, multiple filtering techniques can be applied to the band - pass - filtered signal. During peak detection 510, peak detection is performed to confirm that the peaks of the

[0039] filtered signal correspond to the typical heart rate range of a human wearer. Peak detection 510 can be based on a predetermined threshold (e.g., looking only at peaks larger than a magnitude of 0.05 mmHg). Additionally or alternatively, peak detection 510 can be based on the examination of a repeating signal having a frequency within the typical heart rate range of a human wearer (e.g., expanded to 30 - 120 bpm for a margin), regardless of magnitude. For example, to confirm that a repeating signal having a frequency within the heart rate range of a typical human wearer is detected, Numerical analysis calculations can be performed. Additionally or alternatively, peak detection 510 can be based on identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. Of course, multiple peak detection techniques can be used during peak detection 510. In some embodiments, peak detection 510 includes a combination of peak detection based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. Computer-executable instructions cause one or more processors 7 to determine 512 whether characteristics of the wearer's pulse were detected during peak detection 510. If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 During peak detection 510, it is natural that multiple peak detection techniques can be used. In some embodiments, peak detection 510 is based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. During peak detection 510, multiple peak detection techniques can be used. In some embodiments, peak detection 510 is based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. During peak detection 510, multiple peak detection techniques can be used. In some embodiments, peak detection 510 is based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. During peak detection 510, multiple peak detection techniques can be used. In some embodiments, peak detection 510 is based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. During peak detection 510, multiple peak detection techniques can be used. In some embodiments, peak detection 510 is based on a predetermined threshold and identifying the highest peaks and that the frequencies of those peaks are within the expected heart rate range of a typical human wearer. This is because the signal-to-noise ratio is sufficiently high for the pulse to be clearly distinguishable. from which it follows.

[0040] Computer-executable instructions cause one or more processors 7 to determine 512 whether characteristics of the wearer's pulse were detected during peak detection 510. If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 Computer-executable instructions cause one or more processors 7 to determine 512 whether characteristics of the wearer's pulse were detected during peak detection 510. If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the result of the positive determination can be displayed 516. For example, display 516 can include transmitting a visual display to a display device associated with compression system 1. Additionally or alternatively, display 516 can include incrementing and / or pausing a timer (e.g., timer 31). Additionally or alternatively, if it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If it is determined 512 that pulse characteristics are present, the computer-executable instructions cause one or more processors 7 to correlate the specified blood pressure with the wearer's arterial blood pressure. When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 When displayed 516, the process ends at step 518 and returns to step 502. If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 If no impulse is detected at step 512, the computer-executable instructions cause one or more processors 7 to return a null value at step 514. After step 514, the process ends at step 518 and sampling 5 Return to 02.

[0041] In one aspect, to provide compression therapy treatment to a wearer of a garment, a controller (e.g., controller 5) for controlling the inflation and deflation of at least one bladder (e.g., bladders 13a, 13b, 13c) of the garment includes one or more processors (e.g., processor 7), and a non-transitory computer-readable storage medium (e.g., non-transitory computer-readable storage medium 33). The non-transitory computer-readable storage medium includes computer-executable instructions for causing one or more processors to receive, from a pressure sensor (e.g., pressure sensor 27), a signal indicative of a fluid pressure within at least one bladder of the garment, and to determine whether the received signal includes an oscillation amplitude as a function of time (e.g., a timing signal and / or timing data provided by timer 31). The non-transitory computer-readable storage medium also includes computer-executable instructions for causing one or more processors to estimate a blood pressure of a wearer of the garment based at least in part on a determination of whether the received signal includes an oscillation amplitude as a function of time. including the inflation and deflation of at least one bladder (e.g., bladders 13a, 13b, 13c) of the garment A controller (e.g., controller 5) for controlling one or more processors (e.g., processor 7), and a non-transitory computer-readable storage medium (e.g., non-transitory computer-readable storage medium 33). The non-transitory computer-readable storage medium causes one or more processors to receive, from a pressure sensor (e.g., pressure sensor 27), a signal indicative of a fluid pressure within at least one bladder of the garment and to determine whether the received signal includes an oscillation amplitude as a function of time (e.g., a timing signal and / or timing data provided by timer 31). The non-transitory computer-readable storage medium also causes one or more processors to estimate a blood pressure of a wearer of the garment based at least in part on a determination of whether the received signal includes an oscillation amplitude as a function of time. including the inflation and deflation of at least one bladder (e.g., bladders 13a, 13b, 13c) of the garment A controller (e.g., controller 5) for controlling one or more processors (e.g., processor 7), and a non-transitory computer-readable storage medium (e.g., non-transitory computer-readable storage medium 33). The non-transitory computer-readable storage medium causes one or more processors to receive, from a pressure sensor (e.g., pressure sensor 27), a signal indicative of a fluid pressure within at least one bladder of the garment and to determine whether the received signal includes an oscillation amplitude as a function of time (e.g., a timing signal and / or timing data provided by timer 31).

[0042] In some embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated. including the inflation and deflation of at least one bladder (e.g., bladders 13a, 13b, 13c) of the garment

[0043] In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated at a substantially constant pressure. including the inflation and deflation of at least one bladder (e.g., bladders 13a, 13b, 13c) of the garment including instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated at a substantially constant pressure.

[0044] In some embodiments, the substantially constant pressure varies by less than 10 percent over the period of the determination.

[0045] In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure over a period longer than about 5 seconds and shorter than about 60 seconds.

[0046] In some embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure at predetermined intervals.

[0047] In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal between at least one treatment compression cycle of the bladder.

[0048] In some embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal based at least in part on user input.

[0049] In certain embodiments, the non - transitory computer - readable storage medium further includes computer - executable instructions for causing one or more processors to detect whether at least one bladder of the compression garment is in communication with a pressure sensor, and the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal based at least in part on the detection of communication between at least one bladder and the pressure sensor.

[0050] In some embodiments, the detected communication between the compression garment and the pressure sensor is a fluid communication.

[0051] ​​​​​​​​​​​In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated to a non-therapeutic pressure.

[0052] In some embodiments, the non-therapeutic pressure is about 160 mmHg or greater.

[0053] In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a first signal indicative of fluid pressure within a first bladder and a second signal indicative of fluid pressure within a second bladder, and instructions for determining whether the received signals include an oscillation amplitude, wherein the instructions for determining whether the received signals include an oscillation amplitude include instructions for determining whether the first signal and the second signal each include an oscillation amplitude.

[0054] In some embodiments, the instructions for determining whether the received signals include an oscillation amplitude include instructions for band-pass filtering the received signals to extract frequencies from about 0.5 Hz to about 25 Hz (e.g., band-pass filter 506).

[0055] In certain embodiments, the instructions for determining whether the received signals include an oscillation amplitude further include instructions for smoothing the band-pass filtered signals (e.g., additional filtering 508)

[0056] In some embodiments, the instructions for determining whether the received signals include an oscillation amplitude further include instructions for low-pass filtering the band-pass filtered signals at a frequency of about 5 Hz or less (e.g., additional filtering 508).

[0057] ​​​​​Instructions for determining whether a received signal includes a vibration amplitude includes instructions for detecting a peak of the signal (e.g., peak detection 510).

[0058] In some embodiments, the instructions for detecting a peak of the signal include instructions for detecting a peak in a frequency range of from about 0.5 Hz to about 4 Hz.

[0059] In certain embodiments, the instructions for detecting a peak of the signal include instructions for detecting a peak corresponding to a fluid pressure variation exceeding about 0.05 mmHg .

[0060] In some embodiments, the instructions for determining whether a received signal includes a vibration amplitude include instructions for detecting a repeating signal within a frequency range of from about 0.5 Hz to about 4 Hz .

[0061] In certain embodiments, the vibration amplitude as a function of time of the received signal represents the pulse of the wearer of the garment .

[0062] In some embodiments, the non - transitory computer - readable storage medium further includes computer - executable instructions for correlating an estimated blood pressure with the arterial blood pressure of the wearer .

[0063] In another aspect, a system (e.g., compression system 1) includes a compression garment (e.g., compression garment 10) including at least one inflatable and deflatable bladder (e.g., bladders 13a, 13b, 13c), the compression garment being securable around one or more extremities of a wearer. The system includes a controller (e.g., for controlling inflation and deflation of at least one bladder of the garment to provide a compression therapy treatment to the wearer of the garment . ​ then, it further includes a controller 5). The controller 5 includes one or more processors (for example , processor 7), and one or more processors are caused to receive a signal indicating the fluid pressure within at least one bladder of the garment from a pressure sensor (for example, pressure sensor 27) and to determine whether the received signal includes an oscillation amplitude as a function of time (for example, a timing signal and / or timing data provided by timer 31). The memory (for example, non-transitory computer-readable storage medium 33) includes instructions for this purpose. The non-transitory computer -readable storage medium also includes computer-executable instructions for causing one or more processors to estimate the blood pressure of the wearer of the garment based at least in part on whether the received signal includes an oscillation amplitude as a function of time . For example, this can include an oscillometric method of inflating the bladder to a pressure sufficient to occlude the underlying arterial vessel . In one embodiment, the occlusion pressure is referred to as the systolic pressure, and the pressure that results in the maximum pulsation amplitude is referred to as the mean arterial pressure . Alternative techniques can utilize pulse wave velocity theory to provide more continuous blood pressure measurements . For example, the oscillation waveform is first measured at one of the bladders, and a second bladder is used to measure the time it takes for the same pressure waveform to travel along the arterial tree to the second bladder . The shorter the required time, the higher the underlying pressure. In yet another embodiment, the inflation profile of the first bladder can be used to generate a measurement signal at the second bladder . As a result, the known generated signal can be used to cancel noise related to patient movement and improve the fidelity of the underlying blood pressure waveform .

[0064] In certain embodiments, the system includes a pump (e.g., pressurized fluid source 21) and at least one valve (e.g., valves 25a, 25b, 25c) in fluid communication with the pump and at least one expandable and contractible bladder. The at least one valve is in electrical communication with a controller, and the controller's non-transitory computer-readable storage medium also includes computer-executable instructions for causing one or more processors to operate the at least one valve to control fluid communication between the pump and the at least one expandable and contractible bladder. .

[0065] In some embodiments, the system also includes a pump in fluid communication with at least one expandable and contractible bladder. The pump is in electrical communication with the controller, and the controller's non-transitory computer-readable storage medium also includes computer-executable instructions for causing one or more processors to adjust the speed of the pump.

[0066] In certain embodiments, when at least one expandable and contractible bladder is secured around a limb of a wearer, it extends at least partially around a portion (e.g., including and up to the perimeter) of the wearer's limb.

[0067] In another aspect, a controller (e.g., controller 5) for controlling the expansion and contraction of at least one bladder (e.g., bladders 13a, 13b, 13c) of a garment (e.g., compression garment 10) to provide compression therapy to a wearer includes one or more processors (e.g., processor 7) and a non-transitory computer-readable storage medium (e.g., non-transitory computer-readable storage medium 33). The non-transitory computer-readable ​​​​​​​​​​​​​​The memory medium causes one or more processors to receive a signal indicating the fluid pressure within at least one bladder of the garment from a pressure sensor (e.g., pressure sensor 27), and includes computer-executable instructions for determining whether the received signal includes an indication of the wearer's pulse. The non-transitory computer-readable memory medium also includes computer-executable instructions for causing one or more processors to identify the wearer's blood pressure of the garment, based at least in part on a determination of whether the received signal includes a signal indicating the wearer's pulse. In some embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated. In certain embodiments, the instructions for receiving a signal indicative of fluid pressure include instructions for receiving a signal indicative of fluid pressure while at least one bladder is inflated at a substantially constant pressure. In some embodiments, the instructions for determining whether the received signal includes an indication of the wearer's pulse include instructions for detecting a repeating signal within a frequency range of from about 0.5 Hz to about 4 Hz. In certain embodiments, the computer-executable instructions include instructions for correlating the identified blood pressure with the wearer's arterial blood pressure.

[0068] In another aspect, a system (e.g., compression system 1) includes a compression garment (e.g., bladders 13a, 13b, 13c) including at least one inflatable and deflatable bladder.

[0069]

[0070]

[0071]

[0072] ​​​​​​​​​​​For example, it includes a compression garment 10), and the compression garment can be fixed around the limbs of the wearer. It is. The system is for providing compression therapy treatment to the wearer of the garment. It further includes a controller (e.g., controller 5) for controlling the inflation and deflation of at least one bladder of the garment. The controller includes one or more processors (e.g., processor 7), and the one or more processors receive a signal indicating the fluid pressure in at least one bladder of the garment from a pressure sensor (e.g., pressure sensor 27). It also includes a non - transitory computer - readable storage medium (e.g., non - transitory computer - readable storage medium 33) containing instructions for determining whether the received signal includes an indication of the wearer's pulse. The non - transitory computer - readable storage medium also includes computer - executable instructions for causing the one or more processors to identify the blood pressure of the wearer of the garment, at least partially based on the determination of whether the received signal includes a signal indicating the wearer's pulse.

[0073] In some embodiments, the system also includes a pump (e.g., pressurized fluid source 21) and at least one valve (e.g., valves 25a, 25b, 25c). The at least one valve is in fluid communication with the pump and at least one inflatable and deflatable bladder. The at least one valve is also in electrical communication with the controller. The non - transitory computer - readable storage medium of the controller also includes computer - executable instructions for causing the one or more processors to operate at least one valve to control the fluid communication between the pump and at least one inflatable and deflatable bladder.

[0074] In certain embodiments, the system also includes a pump in fluid communication with at least one expandable and contractible bladder. The pump is in electrical communication with a controller. The non-transitory computer-readable storage medium of the controller also includes computer-executable instructions for causing one or more processors to adjust the speed of the pump. Embodiments can include one or more of the following advantages. In some embodiments, the determination of the wearer's blood pressure is performed using a signal indicative of the pressure within the inflatable bladder of the compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to the monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurements, a more accurate indication of the wearer's compliance with a treatment protocol, and / or can reduce the burden on the caregiver with respect to monitoring the wearer's vital parameters. The display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort compared to monitoring the vital parameters of a wearer undergoing treatment. Although the compression system has been described as being used with a compression sleeve that extends to the thigh, it will be appreciated that the compression system can be used with other types of compression garments, additionally or alternatively. For example, the compression system can be used with a compression garment that extends to the thigh.

[0075] Although specific embodiments have been described, additional or alternative embodiments are possible.

[0076] In some embodiments, the determination of the wearer's blood pressure is performed using a signal indicative of the pressure within the inflatable bladder of the compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to the monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurements, a more accurate indication of the wearer's compliance with a treatment protocol, and / or can reduce the burden on the caregiver with respect to monitoring the wearer's vital parameters. The display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort compared to monitoring the vital parameters of a wearer undergoing treatment. Although the compression system has been described as being used with a compression sleeve that extends to the thigh, it will be appreciated that the compression system can be used with other types of compression garments, additionally or alternatively. For example, the compression system can be used with a compression garment that extends to the thigh. Although specific embodiments have been described, additional or alternative embodiments are possible. In some embodiments, the determination of the wearer's blood pressure is performed using a signal indicative of the pressure within the inflatable bladder of the compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to the monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurements, a more accurate indication of the wearer's compliance with a treatment protocol, and / or can reduce the burden on the caregiver with respect to monitoring the wearer's vital parameters. The display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort compared to monitoring the vital parameters of a wearer undergoing treatment. Although the compression system has been described as being used with a compression sleeve that extends to the thigh, it will be appreciated that the compression system can be used with other types of compression garments, additionally or alternatively. For example, the compression system can be used with a compression garment that extends to the thigh. Although specific embodiments have been described, additional or alternative embodiments are possible. In some embodiments, the determination of the wearer's blood pressure is performed using a signal indicative of the pressure within the inflatable bladder of the compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to the monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurements, a more accurate indication of the wearer's compliance with a treatment protocol, and / or can reduce the burden on the caregiver with respect to monitoring the wearer's vital parameters. The display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort compared to monitoring the vital parameters of a wearer undergoing treatment. Although the compression system has been described as being used with a compression sleeve that extends to the thigh, it will be appreciated that the compression system can be used with other types of compression garments, additionally or alternatively. For example, the compression system can be used with a compression garment that extends to the thigh. Although specific embodiments have been described, additional or alternative embodiments are possible.

[0077] Although specific embodiments have been described, additional or alternative embodiments are possible.

[0078] Although the compression system has been described as being used with a compression sleeve that extends to the thigh, it will be appreciated that the compression system can be used with other types of compression garments, additionally or alternatively. For example, the compression system can be used with a compression garment that extends to the thigh. Although specific embodiments have been described, additional or alternative embodiments are possible. In some embodiments, the determination of the wearer's blood pressure is performed using a signal indicative of the pressure within the inflatable bladder of the compression garment during a static period, providing a real-time automatic display of the wearer's blood pressure. Compared to the monitoring of multiple medical devices performed by a caregiver, the real-time automatic display of the wearer's blood pressure described herein can provide more accurate blood pressure measurements, a more accurate indication of the wearer's compliance with a treatment protocol, and / or can reduce the burden on the caregiver with respect to monitoring the wearer's vital parameters. The display of the wearer's blood pressure described herein can provide monitoring of the wearer's vital parameters with minimal equipment and improved comfort compared to monitoring the vital parameters of a wearer undergoing treatment. configured to be placed on a compression sleeve and / or different regions of the wearer's body, different numbers of bladders can be used with the sleeve.

[0079] Embodiments can be implemented in digital electronic circuitry, or in computer hardware, firmware, so ftware, or combinations thereof. The controller of the compression system can be tangibly implemented or stored in a machine-readable storage device for execution by a programmable processor, and the method operations can be performed by a programmable processor executing a program of instructions to operate on input data to generate output, thereby performing the functions of the controller of the compression system. The controller of the compression system is connected to receive data and instructions from a data storage system and at least one input device, and to send data and instructions to the data storage system and at least one output device, and can be implemented in one or more computer programs executable by a programmable system including at least one programmable processor. Each computer program can be implemented in a high-level procedural or object-oriented programming language, or, if desired, in assembly or machine language. In any case, the language can be a compiled or interpreted language. Regardless, the language can be a compiled language or an interpreter language. Any suitable processor includes, by way of example, a dedicated microprocessor. Generally, the

[0080] processor receives instructions and data from read-only memory or random access memory. Generally speaking, The computer includes one or more mass storage devices for storing data files. Such devices include magnetic disks such as internal hard disks and removable disks, magneto-optical disks, and optical disks. Storage devices suitable for tangibly implementing the instructions and data of computer programs include, by way of example, all forms of non-volatile memory such as semiconductor memory devices such as EPROM, E EPROM, and flash memory devices, magnetic disks such as internal hard disks and removable disks, magneto-optical disks, and CD-ROM disks. Any of the foregoing can be supplemented by or incorporated into an ASIC (application specific integrated circuit) or FPGA (field programmable logic array).

[0081] Numerous embodiments have been described. Nevertheless, it will be understood that various modifications can be made without departing from the spirit and scope of the present disclosure. For example, although a controller with a single pressure sensor has been described, additional pressure sensors (e.g., one for each inflatable bladder) can be used without departing from the scope of the present disclosure. Accordingly, other embodiments are within the scope of the appended claims. ​

Claims

1. A compression system comprising a compression therapy garment provides a method for estimating the blood pressure of the wearer of the compression therapy garment, The compression system comprises a controller for controlling the inflation and deflation of at least one bladder of the compression garment in order to apply gradient pressure to the wearer's lower limbs during a compression therapy cycle. The aforementioned blood pressure includes systolic blood pressure and diastolic blood pressure. The compression therapy cycle comprises an inflation phase of the at least one bladder, a deflating phase of the at least one bladder, and a depressurization or ventilation phase of the at least one bladder, and the method is The controller receives a signal from the pressure sensor indicating the fluid pressure in the at least one bladder during the decay phase of the compression therapy cycle, The controller analyzes one or more waveforms of the received signal to determine whether the received signal includes an oscillation amplitude as a function of time that represents the wearer's heart rate. In response to the determination that the received signal includes an oscillation amplitude as a function of time representing the wearer's heart rate, the controller estimates the wearer's blood pressure based on the magnitude of the oscillation amplitude using one or more algorithms of the oscillometric method. Methods that include...

2. The method according to claim 1, wherein the received signal is a signal indicating fluid pressure within a single bladder of the compression therapy garment.

3. The method according to claim 1, further comprising the controller detecting features indicating the wearer's heart rate from a pressure waveform representing the compression therapy cycle.

4. The method according to claim 1, further comprising the controller extracting frequencies related to the human heart cycle from the received signal.

5. The method according to claim 1, further comprising the controller processing the extracted signal to clarify the vibration amplitude related to the wearer's pulse, such that the vibration amplitude in the signal is more pronounced when displayed on a display device compared to the unprocessed extracted signal.

6. The method according to claim 1, wherein the at least one bladder is inflated during the inflation phase of the compression therapy cycle such that the fluid pressure within the bladder is at least 160 mmHg in order to estimate the wearer's blood pressure.

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