Method for Predicting Aerosol Dose Measurement in the Whole Lung

JP2025517922A5Pending Publication Date: 2026-05-29PHILIP MORRIS PRODUCTS SA

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
PHILIP MORRIS PRODUCTS SA
Filing Date
2023-05-24
Publication Date
2026-05-29

AI Technical Summary

Technical Problem

Current dosimetry models for estimating aerosol deposition in the respiratory system are limited by their inability to accurately capture aerosol behavior in deeper lung regions and are computationally inefficient, lacking detailed representation of aerosol physics and varying breathing profiles.

Method used

A modular respiratory system model that includes a plurality of airway modules representing different generations of the respiratory system, along with an inhalation topology module to set input flows based on captured aerosol inhalation profiles, enabling real-time adaptation of inhalation behavior to achieve optimal aerosol deposition.

Benefits of technology

The modular respiratory system model allows for accurate and efficient estimation of aerosol deposition over time in various regions of the respiratory system, providing real-time guidance for optimal aerosol delivery and reducing computational burdens.

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Abstract

A system comprising an aerosol generating device and an inhalation guidance unit is provided. The system comprises one or more processors configured to perform the steps of capturing a user's aerosol inhalation profile of the aerosol generating device, supplying the captured aerosol inhalation profile to a respiratory system model, creating an inhalation guidance instruction based on the respiratory system model, and providing the inhalation guidance instruction to the user with the inhalation guidance unit. A modular respiratory system model and a method for transient aerosol dosing are also provided.
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