Method for Predicting Aerosol Dose Measurement in the Whole Lung
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- PHILIP MORRIS PRODUCTS SA
- Filing Date
- 2023-05-24
- Publication Date
- 2026-05-29
AI Technical Summary
Current dosimetry models for estimating aerosol deposition in the respiratory system are limited by their inability to accurately capture aerosol behavior in deeper lung regions and are computationally inefficient, lacking detailed representation of aerosol physics and varying breathing profiles.
A modular respiratory system model that includes a plurality of airway modules representing different generations of the respiratory system, along with an inhalation topology module to set input flows based on captured aerosol inhalation profiles, enabling real-time adaptation of inhalation behavior to achieve optimal aerosol deposition.
The modular respiratory system model allows for accurate and efficient estimation of aerosol deposition over time in various regions of the respiratory system, providing real-time guidance for optimal aerosol delivery and reducing computational burdens.
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