Composition containing a polyion complex and selected skincare active ingredients

Abstract

To provide a composition containing a hyaluronic acid-based polyion complex with reduced stickiness. [Solution] The present invention relates to a composition comprising (a) at least one cationic polymer, (b) at least one anionic polymer, (c) at least one nonpolymeric acid or salt thereof having two or more pKa values, and (d) at least one skincare active ingredient selected from the group consisting of (d1) microbial lysates, (d2) adenosine compounds, and mixtures thereof, wherein (a) the cationic polymer is selected from polylysine, chitosan, and mixtures thereof, and (b) the anionic polymer is selected from hyaluronic acid, its derivatives, its salts, and mixtures thereof. The composition according to the present invention can exhibit reduced stickiness.

Claims

1. (a) at least one cationic polymer, (b) at least one anionic polymer, (c) at least one nonpolymeric acid or salt thereof having two or more pKa values, (d) At least one skincare active ingredient selected from the group consisting of (d1) microbial lysates, (d2) adenosine compounds, and mixtures thereof. A composition comprising, preferably a cosmetic composition, more preferably a cosmetic composition for keratinous substances such as skin, (a) A cationic polymer is selected from polylysine, chitosan, and mixtures thereof. (b) A composition in which the anionic polymer is selected from hyaluronic acid, its derivatives, its salts, and mixtures thereof.

2. (a) The composition according to claim 1, wherein the cationic polymer is selected from polylysine.

3. The composition according to claim 1 or 2, wherein the amount of (a) cationic polymer in the composition is 0.001% to 15% by mass, preferably 0.002% to 10% by mass, and more preferably 0.003% to 5% by mass, based on the total mass of the composition.

4. (b) The composition according to any one of claims 1 to 3, wherein the anionic polymer is selected from the group consisting of hyaluronic acid, hydrolyzed hyaluronic acid, acetylated hyaluronic acid, hyaluronic acid crosspolymer, salts thereof, and mixtures thereof.

5. (b) The composition according to any one of claims 1 to 4, wherein the anionic polymer is selected from the group consisting of hyaluronic acid, hydrolyzed hyaluronic acid, salts thereof, and mixtures thereof, preferably from the group consisting of hyaluronic acid, hydrolyzed hyaluronic acid, alkali metal salts thereof, and mixtures thereof, and more preferably from the group consisting of hyaluronic acid, sodium hyaluronate, hydrolyzed hyaluronic acid, sodium hydrolyzed hyaluronate, and mixtures thereof.

6. (b) The composition according to any one of claims 1 to 5, comprising, as an anionic polymer, at least two types of hyaluronic acid or salts thereof having different molecular weights, preferably a first hyaluronic acid or salt thereof having a molecular weight of 100 kDa or less and a second hyaluronic acid or salt thereof having a molecular weight of 500 kDa or more, more preferably a first hyaluronic acid or salt thereof having a molecular weight of 50 kDa or less and a second hyaluronic acid or salt thereof having a molecular weight of 1000 kDa or more.

7. The composition according to any one of claims 1 to 6, wherein the amount of (b) anionic polymer in the composition is 0.01% to 15% by mass, preferably 0.05% to 10% by mass, and more preferably 0.1% to 5% by mass, based on the total mass of the composition.

8. (c) The composition according to any one of claims 1 to 7, wherein the nonpolymeric acid or salt thereof having two or more pKa values ​​is an organic acid or salt thereof, preferably a hydrophilic or water-soluble organic acid or salt thereof, more preferably phytic acid or salt thereof.

9. The composition according to any one of claims 1 to 8, wherein the amount of (c) a nonpolymeric acid or salt thereof having two or more pKa values ​​in the composition is 0.001% to 15% by mass, preferably 0.002% to 10% by mass, and more preferably 0.003% to 5% by mass, based on the total mass of the composition.

10. (d1) The microbial lysate is selected from the lysates of the genus Bifidobacterium, preferably Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium animalis, Bifidobacterium lactis, Bifidobacterium infantis, Bifidobacterium adolescentis, and Bifidobacterium pseudocatenulatum. The composition according to any one of claims 1 to 9, selected from lysates of the genus Bifidobacterium, selected from the group consisting of (pseudocatenulatum) and mixtures thereof, more preferably Bifidobacterium longum.

11. The composition according to any one of claims 1 to 10, wherein the amount of (d1) microbial lysate in the composition is 0.01% to 30% by mass, preferably 0.05% to 25% by mass, and more preferably 0.1% to 20% by mass, based on the total mass of the composition.

12. (d2) The composition according to any one of claims 1 to 11, wherein the adenosine compound is selected from the group consisting of adenosine, 2'-deoxyadenosine, adenosine phosphate, and mixtures thereof, and is preferably adenosine.

13. The composition according to any one of claims 1 to 12, wherein the amount of (d2)adenosine compound in the composition is 0.001% to 15% by mass, preferably 0.01% to 10% by mass, and more preferably 0.04% to 5% by mass, based on the total mass of the composition.

14. (e) The composition according to any one of claims 1 to 13, further comprising water.

15. A cosmetic method for a keratinous substance, for example, skin, comprising the step of applying a composition according to any one of claims 1 to 14 to the keratinous substance.

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