Trauma Covering Material
A wound dressing with a nitrite-providing mesh and activator gel generates NO upon interaction with exudate, addressing the challenge of sustained NO delivery and enhancing wound healing by improving blood flow and reducing microbial load.
JP2026516632APending Publication Date: 2026-05-26T J SMITH & NEPHEW
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Patent Information
- Application Number
- JP2025558901
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-04-12
- Filing Date
- 2024-04-11
- Publication Date
- 2026-05-26
AI Technical Summary
Technical Problem
Existing wound dressings struggle to maintain stable and sustained delivery of nitric oxide (NO) due to its short-lived nature and rapid oxidation, which is crucial for enhancing wound healing, particularly in diabetic patients with lower NO levels.
Method used
A wound dressing comprising a cover layer, activator layer, dry nitric oxide source layer, and water absorption/distributing layer, which generates NO upon interaction with wound exudate or aqueous reagents, using a nitrite-providing mesh component embedded with sodium nitrite and an activator gel to produce NO.
Benefits of technology
The dressing effectively generates and delivers NO over time, promoting wound healing by enhancing blood flow, reducing microbial load, and accelerating tissue repair.
✦ Generated by Eureka AI based on patent content.
Abstract
The disclosed embodiments relate to wound dressings capable of generating nitric oxide. The wound dressings may include combinable components, including a mesh component comprising a nitrite-providing layer and a composite component comprising an activator layer, such as an acid-providing layer. The activator layer may contain acidic groups and may be a hydrogel, xerogel, or other suitable material. The nitric oxide source layer may contain nitrite. The wound dressings may include a one-piece application embodiment, in which the mesh and composite components can be combined by removing a separating component. Alternatively, the wound dressings may include a two-piece application embodiment in which the mesh component is inserted into a composite pocket.
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