Cosmetic composition containing biodegradable polymer particles

Abstract

This application relates to a cosmetic composition comprising a PHA resin and a biodegradable polymer resin whose particle size is adjusted to a specific range. The cosmetic composition of this application can be used in the manufacture of various products, such as basic cosmetics, color cosmetics, sunscreen cosmetics, and hair care cosmetics.

Description

Technical Field

[0001] The present disclosure relates to a cosmetic composition containing biodegradable polymer particles. More specifically, the present disclosure relates to a cosmetic composition using biodegradable polymer particles containing polyhydroxyalkanoate (PHA).

Background Art

[0002] Microplastics, which are a major cause of environmental pollution, are the biggest problem in the cosmetics industry. The distribution of cosmetics containing solid plastic particles (microplastics) of 5 mm or less used for purposes such as cleansing and exfoliation is globally prohibited as long as the products are rinsed off. There is also a grace period for general products that are not rinsed off (basic cosmetics, sunscreen, makeup products), and the prohibition of their use will come into effect soon.

[0003] In the case of sunscreen, once the user who has applied it enters the sea, the harmful components are washed into the water, which can cause serious damage to corals and fish and have a significant adverse impact on the marine ecosystem. The prohibited components are octinoxate (ethylhexyl methoxycinnamate) and oxybenzone (benzophenone-3), which are known to cause coral bleaching and damage the DNA of corals. In addition, these are highly toxic components that are known to cause allergies and affect the respiratory and digestive systems, and are therefore evaluated as dangerous by the Environmental Working Group (EWG), a non-profit organization in the United States. Coral reefs, which play an important role in the ecosystem, are essential for the survival of many marine organisms. Furthermore, since the ocean covers 70% of the earth's surface, the protection of the marine ecosystem is very important. In order to protect the marine ecosystem, prohibited components have been specified for sunscreen, and regulations on the use of microplastics have been strengthened.

[0004] As discussed above, the cosmetics industry is increasingly considering the environment and using safe raw materials to protect health.

Prior Art Documents

[0005] [Patent Document 1] Special table number 2015-522065 [Overview of the project] [Problems that the invention aims to solve]

[0006] Polyhydroxyalkanoates (PHAs), as biodegradable polymers, are biocompatible, non-cytotoxic, and have the effect of promoting the regeneration of human dermal fibroblasts, which can help repair damaged skin. Therefore, they are safe when used on the skin and produce a variety of effects, making them widely applicable to personal care products such as base makeup and color makeup cosmetics, sunscreens, and hair care cosmetics.

[0007] As a result of research conducted by the present inventors on cosmetic compositions using polyhydroxyalkanoate (PHA) particles, it was discovered that cosmetic compositions containing a copolymer PHA resin and a biodegradable polymer resin with particle size controlled within a specific range are superior in terms of usability, sensory properties, UV blocking ability, concealing power, non-toxicity, and formulation stability.

[0008] Therefore, the object of this disclosure is to provide a cosmetic composition that is biodegradable, does not pollute the environment, and has excellent properties as a cosmetic. [Means for solving the problem]

[0009] This disclosure provides a cosmetic composition comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise a copolymerized polyhydroxyalkanoate (PHA), the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA), and the biodegradable polymer particles have an average particle diameter of 20 μm or less.

[0010] In one embodiment, the copolymerized polyhydroxyalkanoate (PHA) further comprises repeating units derived from at least one monomer selected from the group consisting of 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-Hhep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

[0011] In another embodiment, the copolymerized polyhydroxyalkanoate (PHA) comprises poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P3HB-co-4HB).

[0012] In yet another embodiment, the copolymerized polyhydroxyalkanoate (PHA) contains repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 3% to 15% by weight, based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

[0013] In yet another embodiment, the copolymerized polyhydroxyalkanoate (PHA) is used in an amount of 0.1% to 30% by weight based on the total weight of the cosmetic composition.

[0014] In yet another embodiment, the cosmetic composition further comprises at least one selected from the group consisting of UV blockers, oils, surfactants, and polyols.

[0015] In yet another embodiment, the UV blocking agent is at least one selected from the group consisting of titanium dioxide (TiO2), zinc oxide (ZnO), dromethrizole, dromethrizole trisiloxane, digalloyl trioleate, disodium phenyl dibenzimidazole tetrasulfonate, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamide triazone, methylene bisbenzotriazolyl tetramethylbutylphenol, methyl anthranilate, benzophenone-4, benzophenone-8, bisethylhexyloxyphenol methoxyphenyl triazine, ethylhexyldimethyl PABA, ethylhexyl salicylate, ethylhexyl triazone, isoamyl p-methoxycinnamate, terephthalylidene dicamphor sulfonic acid, phenylbenzimidazole sulfonic acid, and polysilicone-15.

[0016] In yet another embodiment, the oil is at least one selected from the group consisting of natural oils, vegetable oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, and silicone oils.

[0017] In yet another embodiment, the surfactant is at least one selected from the group consisting of anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, polymeric surfactants, natural surfactants, and silicone surfactants.

[0018] In yet another embodiment, the content of the surfactant is 0.1% to 30% by weight based on the total weight of the cosmetic composition.

[0019] In yet another embodiment, the content of the UV blocking agent is 5% to 35% by weight based on the total weight of the cosmetic composition.

[0020] In yet another embodiment, the oil content is 0.1% to 70% by weight based on the total weight of the cosmetic composition.

[0021] In yet another embodiment, the cosmetic composition has an SPF (sun protection factor) of 30 or more and a PA (protection factor of UVA) of 8 or more.

[0022] In yet another embodiment, the cosmetic composition includes formulations of sun sticks, sun lotions, sunscreens, sun balms, sun sprays, softening lotions, nourishing lotions, lotions, nourishing creams, massage creams, essences, ampoules, eye creams, makeup base creams, primers, foundations, pacts, shampoos, treatments, scalp ampoules, packs, sprays, body washes, cleansing foams, cleansing lotions, cleansing oils, or powders.

[0023] In yet another embodiment, the cosmetic composition is used to manufacture basic cosmetics, color cosmetics, sunscreen cosmetics, or hair care cosmetics.

[0024] The present disclosure also provides a cosmetic composition for UV protection, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise a copolymer polyhydroxyalkanoate (PHA), and the copolymer polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1 wt% to 20 wt% based on the total weight of the copolymer polyhydroxyalkanoate (PHA), and the cosmetic composition has an SPF (sun protection factor) of 30 or more and a PA (protection factor of UVA) of 8 or more.

[0025] The present disclosure also provides a cosmetic composition for skin regeneration, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise a copolymer polyhydroxyalkanoate (PHA), and the copolymer polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1 wt% to 20 wt% based on the total weight of the copolymer polyhydroxyalkanoate (PHA).

Advantages of the Invention

[0026] The cosmetic composition according to the present disclosure contains a copolymer PHA resin and a biodegradable polymer resin with a particle size controlled within a specific range, and is excellent in terms of usability, sensory properties, UV blocking ability, covering power, non-toxicity, and formulation stability.

[0027] Specifically, the cosmetic composition has excellent UVB and UVA blocking booster effects, which reduces the amount of irritating UV filters in the formulation and helps protect the skin from UV damage. In addition, because the PHA particles are round, they provide a smooth feel, improve spreadability, and impart a soft-focus effect to the skin, thereby helping to smooth the skin's texture. Furthermore, because PHA has a high melting point, it remains stable without changing its particle size or shape even when processed at low or high temperatures. Therefore, there are no problems when it is applied to emulsified formulations such as lotions and creams that require processes that operate at high temperatures.

[0028] In particular, this cosmetic composition can be applied to a variety of cosmetics, including those using inorganic or organic UV filters, as well as basic and color cosmetics. Furthermore, because it is readily biodegradable in both soil and ocean, it can effectively contribute to environmental protection.

[0029] As described above, the cosmetic composition of this disclosure is excellent in terms of usability, UV blocking booster effect, and cell proliferation rate, and can therefore be used in the manufacture of various products such as basic cosmetics, color cosmetics, sunscreen cosmetics, and hair care cosmetics. [Modes for carrying out the invention]

[0030] The present disclosure will be described in detail below with reference to embodiments. The embodiments are not limited to those described below. Rather, they can be modified in various forms without altering the essence of the invention.

[0031] In this specification, the term “comprising” is intended to identify specific characteristics, areas, processes, elements, and / or components. Unless otherwise stated, this does not preclude the presence or addition of other characteristics, areas, processes, elements, and / or components.

[0032] In addition, all numerical values ​​used herein to describe the physical properties, dimensions, etc., of elements should be understood to be modified by the term "approximately" unless otherwise specified.

[0033] In numerical ranges that limit the size, physical properties, etc., of the components described herein, if numerical ranges limited only by an upper limit and numerical ranges limited only by a lower limit are given separately, it should be understood that numerical ranges combining these upper and lower limits are also included in the scope of the examples.

[0034] Biodegradable polymer particles The cosmetic composition according to this disclosure contains biodegradable polymer particles.

[0035] Specifically, the biodegradable polymer particles contain polyhydroxyalkanoate (PHA).

[0036] The polyhydroxyalkanoate (PHA) may possess physical properties similar to conventional petroleum-derived synthetic polymers such as polybutylene adipate terephthalate (PBAT), polybutylene succinate (PBS), polybutylene succinate terephthalate (PBST), and polybutylene succinate adipate (PBSA), exhibiting excellent biodegradability and biocompatibility.

[0037] Specifically, PHA, a natural polyester polymer that accumulates in microbial cells, can be completely decomposed in soil and / or oceans into carbon dioxide, water, organic waste, etc., and therefore can have excellent biodegradability without generating microplastics. Accordingly, the cosmetic composition according to this disclosure, because it contains such PHA, can have excellent biodegradability and environmental friendliness.

[0038] In particular, the PHA particles themselves are processed to be round in shape and have a small particle size. When applied to base makeup or color cosmetics, they can provide a soft-focus effect and help improve the user experience.

[0039] In addition, PHA has the function of an SPF booster, so when combined with UV blockers (TiO2, ZnO, etc.) in sunscreen, it can improve spreadability and provide a higher UV protection effect. UVA (long wavelength 320-400nm) has only 1 / 1,000th the energy of UVB (short wavelength 280-320nm), but the amount of light that reaches the Earth's surface is 100 times that of UVB, and it is known to be the main cause of skin pigmentation and aging. In addition to blocking UVB, PHA has an excellent UVA blocking booster effect and has the advantage of blocking a wider range of ultraviolet rays than organic absorbers.

[0040] The PHA may be obtained by cell disruption using mechanical or physical methods, or by cell disruption using non-mechanical or chemical methods. Specifically, the PHA may be a copolymer obtained through an enzymatic catalyzed polymerization process of one or more monomers within living microbial cells.

[0041] More specifically, the biodegradable polymer particles contain copolymerized polyhydroxyalkanoates (PHAs).

[0042] The copolymerized polyhydroxyalkanoate (PHA) may include a copolymer comprising two or more different repeating units having different repeating units randomly distributed in the polymer chain.

[0043] In one embodiment, the copolymerized polyhydroxyalkanoate (PHA) may contain repeating units derived from 4-hydroxybutyrate (4-HB).

[0044] The inclusion of repeating units derived from 4-hydroxybutyrate (4-HB) in the copolymer PHA can improve the physical properties and effects of cosmetic compositions. As a result, it is possible to provide cosmetic compositions that can be used for a variety of purposes.

[0045] In this disclosure, it is important to adjust the content of 4-HB repeating units in the copolymer PHA. That is, the content of 4-HB repeating units in the copolymer PHA may be important in order to achieve the physical properties desired in this disclosure, in particular to enhance biodegradability in vivo and to achieve excellent mechanical properties.

[0046] The content of repeating units derived from 4-hydroxybutyrate (4-HB) is 0.1% by weight or more, 1% by weight or more, 3% by weight or more, 5% by weight or more, 7% by weight or more, 8% by weight or more, 10% by weight or more, 12% by weight or more, 13% by weight or more, 15% by weight or more, 17% by weight or more, 18% by weight or more, 20% by weight or more, or 25% by weight or more, based on the total weight of copolymerized polyhydroxyalkanoate (PHA), and may be 50% by weight or less, 45% by weight or less, 43% by weight or less, 42% by weight or less, 40% by weight or less, 35% by weight or less, 30% by weight or less, 25% by weight or less, or 20% by weight or less.

[0047] In one embodiment, the copolymerized polyhydroxyalkanoate (PHA) may contain repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight, based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

[0048] For example, the content of repeating units derived from 4-hydroxybutyrate (4-HB) may be, but is not limited to, 1% to 20% by weight, 2% to 20% by weight, 3% to 15% by weight, 5% to 15% by weight, or 5% to 10% by weight, based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

[0049] As a specific example, the copolymerized polyhydroxyalkanoate (PHA) may contain repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 3% to 15% by weight, based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

[0050] When the content of 4-HB repeating units in copolymerized polyhydroxyalkanoate (PHA) meets the above range, biodegradability in soil and marine environments can be enhanced, and the stability and physical properties as a cosmetic ingredient can be maintained at an excellent level.

[0051] As described above, copolymer PHA contains one or more 4-HB repeating units, and the degree of crystallinity of copolymer PHA can be adjusted by controlling the content of 4-HB repeating units. In other words, copolymer PHA may be a polymer with controlled crystallinity.

[0052] Copolymer PHAs with adjusted crystallinity may have their crystallinity and amorphous properties adjusted as the disorder in their molecular structure increases. Specifically, the types and ratios of monomers, or the types and / or content of isomers, may be adjusted.

[0053] In addition, the copolymer PHA may contain 4-HB repeating units, and further contain one repeating unit different from the 4-HB repeating units, or two, three, four, five, six, or more repeating units that are different from each other.

[0054] For example, the copolymerized polyhydroxyalkanoate (PHA) may further contain repeating units derived from at least one monomer selected from the group consisting of 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-Hhep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

[0055] Specifically, the copolymerized polyhydroxyalkanoate (PHA) may contain at least one repeating unit selected from the group consisting of 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

[0056] More specifically, the copolymer PHA may include a copolymer comprising repeating units derived from 3-HB and repeating units derived from 4-HB. For example, the copolymer PHA may include poly(3-hydroxybutyrate-co-4-hydroxybutyrate)(3HB-co-4HB).

[0057] For example, the content of repeating units derived from 3-HB may be 50% by weight or more, 55% by weight or more, 60% by weight or more, 64% by weight or more, 70% by weight or more, 75% by weight or more, or 80% by weight or more, based on the total weight of copolymer PHA, and may be 99.9% by weight or less, 99% by weight or less, 95% by weight or less, 90% by weight or less, 85% by weight or less, 80% by weight or less, or 75% by weight or less.

[0058] In addition, copolymer PHA may contain isomers. For example, copolymer PHA may contain structural isomers, enantiomers, or geometric isomers. Specifically, PHA may contain structural isomers.

[0059] The copolymer PHA may have a glass transition temperature (Tg) of, for example, -45°C to 80°C, -35°C to 80°C, -30°C to 80°C, -25°C to 75°C, -20°C to 70°C, -35°C to 5°C, -25°C to 5°C, -35°C to 0°C, -25°C to 0°C, -30°C to -10°C, -35°C to -15°C, -35°C to -20°C, -20°C to 0°C, -15°C to 0°C, or -15°C to -5°C.

[0060] The crystallization temperature (Tc) of the copolymer PHA may not be measured, or it may be, for example, 70°C to 120°C, 75°C to 120°C, 75°C to 115°C, 75°C to 110°C, or 90°C to 110°C.

[0061] The melting temperature (Tm) of the copolymer PHA may not be measured, or it may be, for example, 100°C to 170°C, 110°C to 150°C, or 120°C to 140°C.

[0062] Copolymer PHA may have a weight-average molecular weight (Mw) of, for example, 10,000 g / mol to 1,200,000 g / mol. For example, the weight-average molecular weight of copolymer PHA may be 50,000 g / mol to 1,200,000 g / mol, 100,000 g / mol to 1,200,000 g / mol, 50,000 g / mol to 1,000,000 g / mol, 100,000 g / mol to 1,000,000 g / mol, 100,000 g / mol to 900,000 g / mol, 200,0 00g / mol~1,200,000g / mol, 250,000g / mol~1,150,000g / mol, 300,000g / mol~1,100,000g / mol, 35 0,000g / mol~1,000,000g / mol, 350,000g / mol~950,000g / mol, 100,000g / mol~900,000g / mol, 200 ,000g / mol~800,000g / mol, 200,000g / mol~700,000g / mol, 250,000g / mol~650,000g / mol, 200,00 0g / mol~400,000g / mol, 300,000g / mol~800,000g / mol, 300,000g / mol~600,000g / mol, 400,000g / mol It may also be mol~800,000g / mol, 500,000g / mol~1,200,000g / mol, 500,000g / mol~1,000,000g / mol, 550,000g / mol~1,050,000g / mol, 550,000g / mol~900,000g / mol, or 600,000g / mol~900,000g / mol.

[0063] In one embodiment, the copolymer PHA may be crystalline or semi-crystalline PHA. For example, the crystalline or semi-crystalline PHA may contain, for example, 1% to 25% by weight or 3% to 20% by weight of 4-HB repeating units based on the total weight of the copolymer PHA. In addition, the crystalline or semi-crystalline PHA may have, for example, a glass transition temperature (Tg) of -20°C to 0°C, a crystallization temperature (Tc) of, for example, 75°C to 115°C, and a melting temperature (Tm) of, for example, 110°C to 160°C.

[0064] In another embodiment, the biodegradable polymer particles may further comprise other PHA-based polymers. For example, they may further comprise at least one polymer selected from the group consisting of poly(3-hydroxybutyrate) (P3HB), poly(4-hydroxybutyrate) (P4HB), poly(3-hydroxyhexanoate) (P3HH), poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HB-3HH), poly(3-hydroxyoctanoate) (P3HO), and poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) (P3HB-3HO).

[0065] In another embodiment, the biodegradable polymer particles may be a mixture of one or more synthetic biodegradable polymers other than polyhydroxyalkanoates (PHAs) and naturally occurring biodegradable polymers. Examples of synthetic biodegradable polymers include polylactic acid (PLA), polycaprolactone (PCL), polyglycolic acid (PGA), poly(lactic acid-co-caprolactone) (PLCL), poly(lactic acid-co-glycolic acid) (PLGA), polybutylene succinate (PBS), and poly(butylene adipate-co-terephthalate) (PBAT). Examples of naturally occurring biodegradable polymers include starch, silk fibroin, chitosan, chitin, cellulose, collagen, and gelatin.

[0066] The particle size of the biodegradable polymer particles may be controlled to a specific range.

[0067] In one embodiment, the biodegradable polymer particles have an average particle diameter of 20 μm or less.

[0068] The average particle diameter may be, for example, the particle diameter corresponding to the cumulative percentage of 50% in the particle diameter distribution, i.e., D50.

[0069] Within the above particle size range, it is suitable for use in basic cosmetics, color cosmetics, and sunscreens. On the other hand, if it is outside this range, it may have an unpleasant feel and may cause a foreign body sensation.

[0070] Specifically, the average particle size of the biodegradable polymer particles may be 1 μm to 10 μm, or more specifically, 2 μm to 8 μm.

[0071] The biodegradable polymer particles can be ground into smaller particles using a food mixer or atomizer to obtain a size suitable for cosmetic formulations. In addition, the grinding operation may be repeated two to three times to obtain the appropriate particle size. In addition to the grinding apparatus described above, the particles can also be obtained through various fine particle grinders (jet mills, air jet mills, etc.). Furthermore, the biodegradable polymer particles can be fed into a circular vibrating sieve and sieved to obtain particles of the desired size.

[0072] Cosmetic composition As described above, the cosmetic compositions of this disclosure are prepared using biodegradable polymer particles containing copolymerized polyhydroxyalkanoate (PHA).

[0073] The content of biodegradable polymer particles is 0.1% by weight or more, 0.5% by weight or more, 1% by weight or more, 2% by weight or more, 3% by weight or more, 5% by weight or more, 7% by weight or more, 8% by weight or more, 10% by weight or more, 15% by weight or more, 20% by weight or more, or 25% by weight or more, based on the total weight of the cosmetic composition, and may be 50% by weight or less, 40% by weight or less, 30% by weight or less, 25% by weight or less, 20% by weight or less, or 15% by weight or less.

[0074] Specifically, the content of biodegradable polymer particles may be 0.1% to 50% by weight, 0.1% to 30% by weight, 1% to 30% by weight, 1% to 25% by weight, 1% to 20% by weight, 1% to 15% by weight, 1.5% to 10% by weight, 2% to 10% by weight, 2.5% to 10% by weight, 3% to 50% by weight, 3% to 30% by weight, 3% to 20% by weight, 3% to 10% by weight, 4% to 10% by weight, or 5% to 10% by weight, based on the total weight of the cosmetic composition.

[0075] In addition, the content of copolymerized polyhydroxyalkanoate (PHA) may be 0.1% or more by weight, 0.2% or more by weight, 0.5% or more by weight, 1% or more by weight, 1.5% or more by weight, 2% or more by weight, 2.5% or more by weight, 3% or more by weight, 5% or more by weight, 10% or more by weight, 15% or more by weight, or 20% or more by weight, based on the total weight of the cosmetic composition, and may be 50% or less by weight, 40% or less by weight, 30% or less by weight, 25% or less by weight, 20% or less by weight, 15% or less by weight, or 10% or less by weight.

[0076] In one embodiment, copolymerized polyhydroxyalkanoate (PHA) may be used in an amount of 0.1% to 30% by weight based on the total weight of the cosmetic composition. Specifically, copolymerized polyhydroxyalkanoate (PHA) may be used in an amount of 1% to 20% by weight, 1% to 15% by weight, 2% to 10% by weight, 2.5% to 10% by weight, 3% to 30% by weight, 3% to 20% by weight, 3% to 10% by weight, or 5% to 10% by weight based on the total weight of the cosmetic composition.

[0077] Within the desirable range described above, biodegradability and cell proliferation effects can be further improved, and other cosmetic properties may also become more advantageous.

[0078] The cosmetic composition may further contain at least one selected from the group consisting of UV blockers, oils, surfactants, and polyols.

[0079] The cosmetic compositions according to this disclosure may include a UV-blocking agent. The UV-blocking agent plays a role in blocking UVA (long wavelength 320-400 nm) and UVB (short wavelength 280-320 nm) rays from reaching the skin, thereby preventing pigmentation and aging.

[0080] The UV blocking agent may be at least one selected from the group consisting of, for example, inorganic UV blocking agents, organic UV blocking agents, and organic / inorganic composite UV blocking agents.

[0081] The UV blocking agent may be at least one selected from the group consisting of titanium dioxide (TiO2), zinc oxide (ZnO), dromethrizole, dromethrizole trisiloxane, digalloyl trioleate, disodium phenyl dibenzimidazole tetrasulfonate, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamide triazone, methylene bisbenzotriazolyl tetramethylbutylphenol, methyl anthranilate, benzophenone-4, benzophenone-8, bisethylhexyloxyphenol methoxyphenyl triazine, ethylhexyldimethyl PABA, ethylhexyl salicylate, ethylhexyl triazone, isoamyl p-methoxycinnamate, terephthalylidene dicamphor sulfonic acid, phenylbenzimidazole sulfonic acid, and polysilicone-15.

[0082] In one embodiment, the UV blocking agent may be at least one selected from titanium dioxide (TiO2) and zinc oxide (ZnO).

[0083] The amount of UV blocking agent is 0.1% by weight or more, 1% by weight or more, 3% by weight or more, 5% by weight or more, 10% by weight or more, or 20% by weight or more, based on the total weight of the cosmetic composition, and may be 50% by weight or less, 40% by weight or less, 30% by weight or less, or 25% by weight or less.

[0084] As a specific example, the amount of UV blocking agent may be 5% to 35% by weight based on the total weight of the cosmetic composition.

[0085] In addition, the cosmetic composition may contain a UV-blocking agent in an amount of 1 to 6 parts by weight, 1.5 to 6 parts by weight, or 2 to 4 parts by weight per 1 part by weight of copolymerized polyhydroxyalkanoate (PHA).

[0086] The cosmetic composition according to this disclosure may contain an oil. The oil functions as a moisturizer to protect the skin and also as a softener to soften the cosmetic composition, thereby improving its spreadability.

[0087] The oil may be at least one selected from the group consisting of, for example, natural oils, vegetable oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, and silicone oils.

[0088] In one embodiment, the oil may be at least one selected from the group consisting of dimethicone, cyclomethicone, cyclopentasiloxane, neopentyl glycol dicaprate, ethylhexyl palmitate, C12-15 alkyl benzoate, dicaprylyl carbonate, hexyl laurate, caprylic / capric triglyceride, dicaprylic / propylene glycol dicaprate, and (caprylic / capric) coconut alkyl.

[0089] The oil content is 0.1% by weight or more, 1% by weight or more, 3% by weight or more, 5% by weight or more, 10% by weight or more, or 15% by weight or more, based on the total weight of the cosmetic composition, and may be 70% by weight or less, 50% by weight or less, 30% by weight or less, or 20% by weight or less, but is not limited to these. As a specific example, the oil content may range from 0.1% by weight to 70% by weight based on the total weight of the cosmetic composition.

[0090] In addition, the cosmetic composition may contain 0.1 to 7 parts by weight, 0.5 to 6 parts by weight, or 1 to 5 parts by weight of oil per 1 part by weight of copolymerized polyhydroxyalkanoate (PHA).

[0091] The cosmetic compositions according to this disclosure may contain surfactants. These surfactants enable the uniform dispersion of powdered components or cosmetic compositions in a liquid medium and their uniform spread throughout the product. In addition, they also play a role in preventing the powdered components from separating or settling in the liquid medium, thereby maintaining the stability of the product. As described above, surfactants can be used as dispersants, emulsifiers, and detergents, depending on their function.

[0092] The surfactant may be at least one selected from the group consisting of anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, polymeric surfactants, natural surfactants, and silicone surfactants.

[0093] In one embodiment, the surfactant may include at least one (two or more, three or more, or four or more) selected from the group consisting of cetearyl olivate, sorbitan olivate, cetearyl alcohol, glyceryl monostearate, glyceryl stearate, PEG-100 stearate, C14-22 alcohol, C12-20 alkyl glucoside, polyglyceryl-6 polyricinoleate, polyglyceryl-3 polyricinoleate, polyglyceryl-10 myristate, potassium cetyl phosphate, cetyl PEG / PPG-10 / 1 dimethicone, PEG-10 dimethicone, and stearic acid.

[0094] The surfactant content is 0.1% by weight or more, 1% by weight or more, 3% by weight or more, 5% by weight or more, 10% by weight or more, or 15% by weight or more, based on the total weight of the cosmetic composition, and may be 40% by weight or less, 30% by weight or less, 25% by weight or less, or 20% by weight or less, but is not limited to these. As a specific example, the surfactant content may be 0.1% by weight to 30% by weight based on the total weight of the cosmetic composition.

[0095] In addition, the cosmetic composition may contain a surfactant in an amount of 0.05 to 3 parts by weight or 0.1 to 1.5 parts by weight per 1 part by weight of copolymerized polyhydroxyalkanoate (PHA).

[0096] The cosmetic composition according to this disclosure may contain a polyol. The polyol is an ingredient that enhances the skin's moisturizing ability while ensuring the formulation stability of the cosmetic composition.

[0097] The polyol is not particularly limited, but may contain at least one selected from the group consisting of glycerin, 1,3-butylene glycol, dipropylene glycol, propylene glycol, polyethylene glycol, and 1,2-hexanediol. Specifically, the polyol may contain glycerin, which is economical and has excellent moisturizing properties.

[0098] The polyol content is 0.1% by weight or more, 1% by weight or more, 3% by weight or more, 5% by weight or more, 10% by weight or more, or 15% by weight or more, based on the total weight of the cosmetic composition, and may be 40% by weight or less, 30% by weight or less, 25% by weight or less, or 20% by weight or less, but is not limited to these. As a specific example, the polyol content may be 0.1% by weight to 30% by weight based on the total weight of the cosmetic composition.

[0099] In addition, the cosmetic composition may contain 0.05 to 3 parts by weight, 0.1 to 2 parts by weight, or 0.2 to 1 part by weight of polyol per 1 part by weight of copolymerized polyhydroxyalkanoate (PHA).

[0100] The cosmetic compositions according to this disclosure may further contain purified water to control viscosity and ensure formulation stability. The purified water is not particularly limited, as long as it is a commonly known purified water (e.g., distilled water, deionized water, pure water, etc.).

[0101] The cosmetic compositions according to this disclosure may further include, if necessary, at least one additive selected from the group consisting of humectants, softeners, thickeners, preservatives, neutralizing agents, acidity adjusters, and fragrances.

[0102] The humectants further included in the cosmetic composition according to this disclosure are components that can supply moisture to the skin.

[0103] The softener further included in the cosmetic composition according to this disclosure is an ingredient that can soothe the skin while providing softness. The softener is not particularly limited, but may include at least one selected from the group consisting of natural vegetable oils, ester oils, hydrocarbon oils, higher alcohols, and silicone oils.

[0104] The thickeners further included in the cosmetic compositions according to this disclosure are components that increase the viscosity of the cosmetic composition. The thickeners are not particularly limited, but may include at least one selected from the group consisting of polyquaternium-10, carbomer, sodium chloride, methylcellulose, carboxymethylcellulose, carboxymethylhydroxyguanine, hydroxymethylcellulose, hydroxyethylcellulose, (sodium acryloyldimethyltaurate / VP) crosspolymer, (ammonium acryloyldimethyltaurate / VP) copolymer, (hydroxyethyl acrylate / sodium acryloyldimethyltaurate) copolymer, polyacrylate crosspolymer-6, stearic acid, carrageenan, xanthan gum, gellan gum, cellulose gum, and bentonite.

[0105] The preservatives further included in the cosmetic composition according to this disclosure are ingredients that enhance the storage stability of the cosmetic composition. The preservatives are not particularly limited, but may include at least one selected from the group consisting of ethanol, phenoxyethanol, ethylhexylglycerin, caprylyl glycol, chlorphenesin, and sodium benzoate.

[0106] The neutralizing agent further included in the cosmetic composition according to this disclosure is an ingredient that interacts with the preservatives included in the cosmetic composition to enhance the safety of the cosmetic composition during use. The neutralizing agent is not particularly limited, but may include at least one selected from the group consisting of potassium hydroxide, sodium hydroxide, calcium hydroxide, triethanolamine, trolamine, and aminomethylpropanol.

[0107] The acidity adjuster further included in the cosmetic composition according to this disclosure is an ingredient that adjusts the pH of the cosmetic composition. The acidity adjuster is not particularly limited, but may include at least one selected from the group consisting of citric acid, acetic acid, propionic acid, oxalic acid, glycolic acid, malonic acid, lactic acid, succinic acid, tartaric acid, aspartic acid, maleic acid, glutaric acid, glutamic acid, gluconic acid, sorbic acid, benzoic acid, ascorbic acid, and salicylic acid.

[0108] The fragrance further contained in the cosmetic composition according to this disclosure is an ingredient that imparts fragrance to the cosmetic composition.

[0109] The content of these additives can be appropriately adjusted within a range that does not impair the properties required of the cosmetic composition.

[0110] The cosmetic compositions described herein can be prepared in various formulations.

[0111] For example, the cosmetic composition may include formulations such as sun sticks, sun lotions, sunscreens, sun balms, sun sprays, softening lotions, nourishing lotions, lotions, nourishing creams, massage creams, essences, ampoules, eye creams, makeup base creams, primers, foundations, compacts, shampoos, treatments, scalp ampoules, packs, sprays, body washes, cleansing foams, cleansing lotions, cleansing oils, or powders.

[0112] The cosmetic composition has excellent UV blocking ability. For example, the SPF (sun protection factor) of the cosmetic composition may be 20 or higher, 25 or higher, 30 or higher, 35 or higher, 40 or higher, or 45 or higher, specifically 20-60, 30-55, or 30-50. In addition, the PA (protection factor of UVA) of the cosmetic composition may be 5 or higher, 8 or higher, 10 or higher, or 15 or higher, specifically 5-30, 8-25, 10-25, or 10-20.

[0113] As a specific example, the cosmetic composition may have an SPF (sun protection factor) of 30 or higher and a PA (protection factor of UVA) of 8 or higher.

[0114] Because the cosmetic composition according to this disclosure contains the above-mentioned components, it can ensure formulation stability while possessing excellent biodegradability and UV blocking ability. In particular, because the cosmetic composition according to this disclosure contains the above-mentioned biodegradable polymer particles, it is environmentally friendly and biodegradable, while also being less irritating to the skin and having excellent usability.

[0115] Therefore, the cosmetic compositions according to this disclosure can be used for cosmetic purposes in various fields.

[0116] For example, the cosmetic composition can be used in the manufacture of basic cosmetics, color cosmetics, sunscreen cosmetics, and hair care cosmetics.

[0117] Accordingly, the present disclosure provides a cosmetic composition for UV blocking, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise copolymerized polyhydroxyalkanoate (PHA), the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA), and the cosmetic composition is characterized by having an SPF (sun protection factor) of 30 or more and a PA (protection factor of UVA) of 8 or more.

[0118] Specific examples of the composition and content of biodegradable polymer particles and copolymer PHA contained in the UV-blocking cosmetic composition may be as described above.

[0119] The SPF (sun protection factor) of the UV-blocking cosmetic composition may be 20 or higher, 25 or higher, 30 or higher, 35 or higher, 40 or higher, or 45 or higher, specifically 20-60, 30-55, or 30-50. In addition, the PA (protection factor of UVA) of the cosmetic composition may be 5 or higher, 8 or higher, 10 or higher, or 15 or higher, specifically 5-30, 8-25, 10-25, or 10-20.

[0120] Specifically, the UV-blocking cosmetic composition has excellent UVB and UVA blocking booster effects, which reduces the amount of irritating UV filter in the formulation and helps protect the skin from UV damage. In addition, because the PHA particles are round, they provide a smooth feel, improve spreadability, and impart a soft-focus effect to the skin, thereby helping to smooth the skin's texture. Furthermore, because PHA has a high melting point, it remains stable without changing its particle size or shape even when processed at low or high temperatures. Therefore, there are no problems when it is applied to emulsified formulations such as lotions and creams that require processes that operate at high temperatures.

[0121] In addition, the present disclosure provides a cosmetic composition for skin regeneration, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise copolymerized polyhydroxyalkanoate (PHA), and the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

[0122] Specific examples of the composition and content of biodegradable polymer particles and copolymer PHA contained in the skin regeneration cosmetic composition may be as described above.

[0123] The present disclosure will be described in more detail below with reference to the following examples. However, the following examples are intended to illustrate the present disclosure and are not limited to the scope of the examples.

[0124] Embodiments for carrying out the invention Test Example 1: Preparation of O / W sunscreen and evaluation of its usability The sunscreens containing the inorganic UV blocking agents of Examples 1 and 2 and Comparative Examples 1 and 2 were prepared according to the following preparation method, with the compositions shown in Table 1 below.

[0125] The aqueous phase raw materials were placed in a beaker at room temperature. While mixing using a homomixer (premix, Japan), it was confirmed that the thickener had dissolved transparently. Then, the oil phase raw materials, which had been heated to 80°C and dissolved, were slowly added. After the addition was complete, the mixture was mixed for 10 minutes to ensure complete dispersion and homogenization. After cooling the beaker to 60°C, the inorganic barrier agent was slowly added while mixing. Dispersion and homogenization were carried out for 10 minutes. PHA was slowly added while mixing at 60°C and dispersed and homogenized for 10 minutes. After cooling the beaker to 45°C, the preservative was added and mixed to complete the preparation. The PHA used was pulverized twice in an atomizer, and its average particle size (D50) was approximately 8 μm.

[0126] [Table 1]

[0127] The usability and satisfaction levels of Examples 1 and 2, as well as Comparative Examples 1 and 2, were evaluated.

[0128] The evaluation was conducted by a total of 20 participants: 10 women and 10 men aged 30 to 40. 2g of each cosmetic composition from Examples 1 and 2, and Comparative Examples 1 and 2, was applied to the arm and gently rolled to allow for gradual absorption. Usability and satisfaction were evaluated, and the results are shown in Table 2 below. Usability scores for rolling feel (spreadability), white cast, and finish were evaluated on a scale of 1.0 (very poor), 2.0 (poor), 3.0 (average), 4.0 (good), and 5.0 (very good). Here, a lower degree of whitening due to white cast was rated as better. In addition, user satisfaction was rated on a scale from 0% (very dissatisfied) to 100% (very satisfied).

[0129] [Table 2]

[0130] As shown in Table 2 above, the cosmetic composition of Example 1 was evaluated as excellent in all categories. Specifically, it was evaluated as having a good rolling sensation, minimal white cast, and a refreshing finish. The cosmetic composition of Example 2 was also evaluated as excellent overall, although its score was lower than that of Example 1. The cosmetic composition of Comparative Example 1 was evaluated as superior to Comparative Example 2 in terms of white cast, but scored lower than Examples 1 and 2 in terms of rolling sensation and finish, respectively. The cosmetic composition of Comparative Example 2 was evaluated as having a severe white cast and therefore received the lowest score in terms of satisfaction.

[0131] Test Example 2: Preparation of W / O sunscreen and evaluation of its usability, UV blocking, and opacity. The cosmetic compositions of Examples 3 and 4 and Comparative Examples 3 and 4 were prepared according to the following preparation method, with the compositions shown in Table 3 below.

[0132] The oil phase ingredients were properly dispersed. While mixing using a homomixer (premix, Japan), the aqueous phase ingredients were slowly added over 5 minutes and emulsified. Complete dispersion and homogenization were carried out for 10 minutes. The flavoring was added and mixed until completely dispersed and homogenized, completing the preparation.

[0133] The PHA used was ground twice in an atomizer, and its average particle size (D50) was approximately 8 μm.

[0134] [Table 3]

[0135] The usability and satisfaction of Examples 3 and 4, as well as Comparative Examples 3 and 4, were evaluated.

[0136] The evaluation was conducted by a total of 20 participants: 10 women and 10 men in their 30s and 40s. 2g of each cosmetic composition from Examples 3 and 4, and Comparative Examples 3 and 4, was applied to the arm and gently rolled to allow for gradual absorption. Usability and satisfaction were evaluated in the same manner as in Test Example 1, and the results are shown in Table 4 below.

[0137] [Table 4]

[0138] As shown in Table 4 above, the cosmetic composition of Example 3 was rated as excellent in all categories. Specifically, it was rated as having a good rolling sensation, minimal white cast, and a soft finish. The cosmetic composition of Example 4 was also rated as excellent overall, although its score was lower than that of Example 3. The cosmetic composition of Comparative Example 3 was rated as above average in terms of white cast, but scored lower than Examples 3 and 4 in terms of rolling sensation and finish, respectively. The cosmetic composition of Comparative Example 4 was rated as having a severe white cast and therefore received the lowest score in terms of satisfaction.

[0139] Furthermore, the in vitro UV blocking effect of the cosmetic compositions of Examples 1-4 and Comparative Examples 1-4 was measured using an SPF-290AS (Solar Light, USA) device. The results of the UV blocking tests are summarized in Table 5 below.

[0140] In addition, since white cast is an essential factor to consider when manufacturing inorganic sunscreens, the opacity index of the cosmetic compositions of Examples 1-4 and Comparative Examples 1-4 was measured to check for white cast. The results are shown in Table 5 below.

[0141] The opacity index was calculated using the following formula 1. A value closer to 1 indicates higher opacity (i.e., white cast or coverage). For this purpose, 1 g of each cosmetic composition from Examples 1-4 and Comparative Examples 1-4 was applied to black and white paper using a film-forming applicator to form films. After drying for 1 hour, the L value was measured using a colorimeter (Coloremeter NR-60CP).

[0142] [Equation 1] Opacity index = L value of film on white paper / L value of film on black paper

[0143] [Table 5]

[0144] As shown in Table 5 above, the cosmetic composition of Example 3, which contained inorganic UV-blocking agents such as zinc oxide and titanium dioxide, and PHA (containing 12% 4HB repeating units), showed the highest UV blocking rate. In addition, the cosmetic composition of Example 1, which did not contain zinc oxide but contained titanium dioxide and PHA (containing 12% 4HB repeating units), also showed a relatively high UV blocking rate. The UV blocking rates of Examples 2 and 4 were also excellent.

[0145] In contrast, the cosmetic compositions of Comparative Examples 2 and 4, which contained inorganic UV blockers but no PHA, showed the lowest UV blocking rates. On the other hand, the PHA (4HB repeating unit content 0%) in Comparative Examples 1 and 3 was shown to contribute relatively well to the UV blocking effect. Therefore, it was confirmed that both SPF (UVB) and PA (UVA) increased when PHA was used.

[0146] In addition, typically, adding large amounts of titanium dioxide increases white cast. However, Examples 1 and 2, as well as Comparative Example 1, which contained PHA, exhibited higher transparency than Comparative Example 2. The same was true for the cosmetic compositions of Examples 3 and 4, as well as Comparative Example 3, which were prepared as W / O creams. From this, it can be understood that PHA helps to disperse inorganic UV-blocking agents.

[0147] Considering usability, UV blocking, and opacity as described above, it can be seen that the cosmetic compositions of Examples 1-4 produced satisfactory results.

[0148] Test Example 3: Preparation of a makeup base and evaluation of its usability The cosmetic compositions of Example 5 and Comparative Examples 5 and 6 were prepared according to the following preparation method, with the compositions shown in Table 6 below.

[0149] The oil phase ingredients were properly dispersed. Using a homomixer (premix, Japan), the aqueous phase ingredients were slowly added over 5 minutes while mixing and emulsified. Complete dispersion and homogenization were carried out for 10 minutes. After adding the flavoring, the mixture was mixed until completely dispersed and homogenized, completing the preparation.

[0150] The PHA used was ground three times in an atomizer, and its average particle size (D50) was approximately 5 μm.

[0151] [Table 6]

[0152] The above component 6 was obtained by uniformly mixing titanium dioxide, chromium oxide green, and talc in a weight ratio of 65:7:28, and then grinding the mixture twice in an atomizer.

[0153] The usability and sensory characteristics of Example 5 and Comparative Examples 5 and 6 were evaluated. The evaluation was conducted by 20 women in their 30s and 40s. 2g of each cosmetic composition from Example 5 and Comparative Examples 5 and 6 was applied to the arm and gently rolled to allow for mild absorption. The usability and sensory characteristics were evaluated, and the results are shown in Table 7 below. Scores for rolling sensation (spreadability), adhesion, durability, soft-focus effect, and makeup finish were evaluated on a scale of 1.0 (very poor), 2.0 (poor), 3.0 (average), 4.0 (good), and 5.0 (very good).

[0154] [Table 7]

[0155] As shown in Table 7 above, the cosmetic composition of Example 5 was evaluated as excellent in all categories. Specifically, it was evaluated as excellent in rolling sensation, adhesion, durability, soft-focus effect, and makeup finish. From the above, it can be understood that cosmetic compositions containing PHA improve the heavy feel and thick makeup finish of colorants (clay minerals).

[0156] In particular, cosmetic compositions containing PHA are understood to offer a superior user experience comparable to that of polymethylsilsesquioxane, a common silicone powder used to improve the finish and soft-focus effect of makeup bases.

[0157] Test Example 4: Preparation of a skin regeneration cream and its in vitro evaluation of cytotoxicity recovery. The cosmetic compositions of Examples 6 and 7 and Comparative Example 7 were prepared according to the following preparation method, with the compositions shown in Table 8 below.

[0158] The aqueous phase ingredients were placed in a beaker and heated to 80°C. While mixing using a homomixer (premix, Japan), the oil phase ingredients, which had been heated to 80°C and dissolved, were slowly added and emulsified. Complete dispersion and homogenization were carried out for 10 minutes. The mixture was cooled to 60°C and a thickener was added. The mixture was mixed for 5 minutes to complete dispersion and homogenization. The mixture was cooled to 50°C and a neutralizing agent was added. The mixture was mixed for 5 minutes to complete dispersion and homogenization, completing the preparation.

[0159] The PHA used was ground three times in an atomizer, and its average particle size (D50) was approximately 5 μm.

[0160] [Table 8]

[0161] Keratinocytes were placed in 24-well plates in DMEM (Dulbecc's Modified Eagle Medium, Gibco) supplemented with 10% FBS, in a 2x10⁶ arrangement. 5 Cells were seeded at a cell / well concentration and cultured for 1 day in a humidified 37°C, 5% CO2 incubator. After replacing with serum-free DMEM, the cells were damaged by exposure to fluorescent sunlight in the UV wavelength range of 240-360 nm for 1 minute. After UV exposure, the cosmetic compositions of Examples 6 and 7 and Comparative Example 7 were inoculated at a constant concentration (v / v) and cultured for 3 days. After culturing, the cell proliferation effect was measured using MTT analysis, and the results are shown in Table 9 below.

[0162] [Table 9]

[0163] As shown in Table 9 above, the sample treated with the cosmetic composition of Example 6 at 10,000 ppm showed the best cell proliferation effect, followed by the sample treated with the cosmetic composition of Example 7 at 10,000 ppm.

[0164] In contrast, cell proliferation was not achieved with the cosmetic composition of Comparative Example 7. From this, it can be understood that the cell proliferation effect in Examples 6 and 7 was caused by proliferation due to the use of PHA. Specifically, samples treated with the cosmetic composition containing PHA showed a good cell proliferation rate. Since cell proliferation was observed without reduction, it was confirmed that there was no cytotoxicity.

[0165] Test Example 5: Evaluation of Formulation Stability The formulation stability of the cosmetic compositions of Examples 1-7 and Comparative Examples 1-7, prepared as described above, was evaluated.

[0166] Each cosmetic composition was evaluated for long-term storage stability at 4°C, 25°C, 45°C, and 50°C for 1 week, 2 weeks, 1 month, and 3 months. The evaluation criteria are summarized in Table 10 below, and the evaluation results are shown in Table 11.

[0167] [Table 10]

[0168] [Table 11]

[0169] As shown in Table 11 above, the cosmetic compositions of Examples 1 to 7 exhibited overall excellent long-term storage stability.

[0170] However, in the case of particles with a 0% 4HB content in PHA, such as in Comparative Examples 1 and 3, it was not easy to prepare uniform particles during grinding due to their high crystallinity and brittle nature. When the cosmetic composition formulations of Comparative Examples 1 and 3 were spread, foreign matter could sometimes be felt from the PHA particles.

[0171] Through the examples, various cosmetic compositions have been prepared, but the scope of this disclosure is not limited thereto. They can also be prepared in the form of softening lotions, nourishing lotions, lotions, nourishing creams, massage creams, essences, eye creams, BB creams, CC creams, primers, foundations, pacts, shampoos, conditioners, scalp ampoules, cleansing creams, cleansing foams, cleansing waters, packs, sprays, powders, and the like.

Claims

1. A cosmetic composition comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise copolymerized polyhydroxyalkanoate (PHA), the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA), and the biodegradable polymer particles have an average particle diameter of 20 μm or less.

2. The cosmetic composition according to claim 1, wherein the copolymerized polyhydroxyalkanoate (PHA) further comprises repeating units derived from at least one monomer selected from the group consisting of 2-hydroxybutyrate (2-HB), 3-hydroxybutyrate (3-HB), 3-hydroxypropionate (3-HP), 3-hydroxyvalerate (3-HV), 3-hydroxyhexanoate (3-HH), 3-hydroxyheptanoate (3-Hhep), 3-hydroxyoctanoate (3-HO), 3-hydroxynonanoate (3-HN), 3-hydroxydecanoate (3-HD), 3-hydroxydodecanoate (3-HDd), 4-hydroxyvalerate (4-HV), 5-hydroxyvalerate (5-HV), and 6-hydroxyhexanoate (6-HH).

3. The cosmetic composition according to claim 1, wherein the copolymerized polyhydroxyalkanoate (PHA) comprises poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P3HB-co-4HB).

4. The cosmetic composition according to claim 1, wherein the copolymerized polyhydroxyalkanoate (PHA) contains repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 3% to 15% by weight, based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

5. The cosmetic composition according to claim 1, wherein the copolymerized polyhydroxyalkanoate (PHA) is used in an amount of 0.1% to 30% by weight based on the total weight of the cosmetic composition.

6. The cosmetic composition according to claim 1, further comprising at least one selected from the group consisting of UV blockers, oils, surfactants, and polyols.

7. The cosmetic composition according to claim 6, wherein the surfactant is at least one selected from the group consisting of anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, polymeric surfactants, natural surfactants, and silicone surfactants.

8. The aforementioned UV blocking agent is titanium dioxide (TiO 2 The cosmetic composition according to claim 6, wherein at least one selected from the group consisting of ), zinc oxide (ZnO), drometrizole, drometrizole trisiloxane, digalloyl trioleate, disodium phenyl dibenzimidazole tetrasulfonate, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamide triazone, methylene bisbenzotriazolyl tetramethylbutylphenol, methyl anthranilate, benzophenone-4, benzophenone-8, bisethylhexyloxyphenol methoxyphenyl triazine, ethylhexyldimethyl PABA, ethylhexyl salicylate, ethylhexyl triazone, isoamyl p-methoxycinnamate, terephthalylidene dicamphor sulfonic acid, phenylbenzimidazole sulfonic acid, and polysilicone-15.

9. The cosmetic composition according to claim 6, wherein the oil is at least one selected from the group consisting of natural oils, vegetable oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, and silicone oils.

10. The cosmetic composition according to claim 6, wherein the content of the surfactant is 0.1% by weight to 30% by weight based on the total weight of the cosmetic composition.

11. The cosmetic composition according to claim 6, wherein the amount of the UV blocking agent is 5% by weight to 35% by weight based on the total weight of the cosmetic composition.

12. The cosmetic composition according to claim 6, wherein the oil content is 0.1% by weight to 70% by weight based on the total weight of the cosmetic composition.

13. The cosmetic composition according to claim 1, wherein the cosmetic composition has an SPF (sun protection factor) of 30 or more and a PA (protection factor of UVA) of 8 or more.

14. The cosmetic composition according to claim 1, wherein the cosmetic composition comprises formulations of a sun stick, sun lotion, sunscreen, sun balm, sun spray, softening lotion, nourishing lotion, lotion, nourishing cream, massage cream, essence, ampoule, eye cream, makeup base cream, primer, foundation, compact, shampoo, treatment, scalp ampoule, pack, spray, body wash, cleansing foam, cleansing lotion, cleansing oil, or powder.

15. The cosmetic composition according to claim 1, which is used in the manufacture of basic cosmetics, color cosmetics, sunscreen cosmetics, or hair care cosmetics.

16. A cosmetic composition for UV blocking, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise copolymerized polyhydroxyalkanoate (PHA), the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA), and the cosmetic composition having an SPF (sun protection factor) of 30 or more and a PA (protection factor of UVA) of 8 or more.

17. A cosmetic composition for skin regeneration, comprising biodegradable polymer particles, wherein the biodegradable polymer particles comprise copolymerized polyhydroxyalkanoate (PHA), and the copolymerized polyhydroxyalkanoate (PHA) comprises repeating units derived from 4-hydroxybutyrate (4-HB) in an amount of 1% to 20% by weight based on the total weight of the copolymerized polyhydroxyalkanoate (PHA).

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