Contact lens systems and methods for evaluating intraocular pressure

Abstract

Devices, systems, and / or methods for assessing intraocular pressure of the cornea of ​​the eye using wearable sensors, and / or use of such assessments for monitoring, diagnosing, and / or treating glaucoma in patients.

Claims

1. A device for evaluating the intraocular pressure (IOP) of a patient's eye, wherein the device is (a) Wearable contact lenses and (b) At least one cantilever sensor attached to the contact lens, the cantilever sensor being configured to measure the elasticity of the cornea of ​​the patient's eye and / or the IOP of the patient's eye, Includes, The contact lens is configured such that the at least one cantilever sensor is positioned adjacent to the surface of the cornea of ​​the patient's eye. The cantilever sensor includes a cantilever tip configured to apply force to the surface of the cornea, device.

2. The device according to claim 1, wherein the cantilever sensor is curved to conform to the surface of the cornea.

3. The device according to claim 1, wherein the device includes a plurality of cantilever sensors positioned outside the central optical zone of the contact lens.

4. The device according to claim 3, wherein the plurality of cantilever sensors are arranged in the paracentral zone of the contact lens.

5. The device according to claim 3, wherein the device is configured to calculate the average elasticity of the cornea and / or the average IOP of the patient's eye based on the elasticity and / or IOP measured by the plurality of cantilever sensors positioned outside the central optical zone of the contact lens.

6. The device according to claim 5, further comprising a processor configured to calculate the average elasticity and / or the average IOP.

7. The device according to claim 5, further comprising an antenna configured to transmit data relating to the mean elasticity and / or the mean IOP to an external device.

8. The device according to claim 1, wherein the contact lens is a corneal contact lens.

9. The device according to claim 8, wherein the corneal contact lens has a diameter of less than 14.5 mm.

10. The device according to claim 1, wherein the contact lens is a scleral contact lens.

11. The device according to claim 10, wherein the scleral contact lens includes an outer scleral skirt formed of a first material different from the second material forming the inner portion of the scleral contact lens.

12. The device according to claim 1, wherein the contact lens is a hybrid contact lens.

13. The device according to claim 1, further comprising an antenna coupled to the at least one cantilever sensor, the antenna being configured to transmit data relating to the measured elasticity and / or IOP to an external device.

14. The device according to claim 13, wherein the antenna is configured to wirelessly transmit data to the external device.

15. The device according to claim 14, wherein the external device is configured to upload the transmitted data to a cloud database.

16. The device according to claim 1, further comprising a drug within the contact lens, wherein the drug is configured to dissolve from the contact lens to the patient.

17. The device according to claim 16, wherein the drug is dissolved into the patient's eye based on the measured elasticity value and / or IOP value exceeding a threshold.

18. The device according to claim 1, further configured to be calibrated to determine IOP based on one or more patient-specific parameters.

19. The device according to claim 18, wherein the device is calibrated to determine IOP based on the measured corneal thickness of the patient's eye.

20. The device according to claim 18, wherein the device is calibrated to determine the IOP based on the measured corneal curvature radius of the patient's eye.

21. The wearable contact lens further includes at least one application-specific integrated circuit ("ASIC") operably coupled to the at least one cantilever sensor, the ASIC being Controlling the operation of the at least one cantilever sensor, Controlling the data flow between the at least one cantilever sensor, Receiving power from a battery or capacitor, and Communication with external data via an antenna placed on the wearable contact lens. The device according to claim 1, configured to perform one or more of the following:

22. A software application for use with a device for evaluating the intraocular pressure of a patient's eye, wherein the device is (a) Wearable contact lenses and (b) At least one cantilever sensor attached to the contact lens, the cantilever sensor being configured to measure the elasticity of the cornea of ​​the patient's eye and / or the IOP of the patient's eye, Includes, The contact lens is configured such that the at least one cantilever sensor is positioned adjacent to the surface of the cornea of ​​the patient's eye. The cantilever sensor includes a cantilever tip configured to apply force to the surface of the cornea, The software application includes a patient user interface configured to perform one or more of the following actions in response to the measured elasticity value and / or the IOP value exceeding a threshold: (a) contact a physician, (b) recommend a change in treatment, or (c) not make a change. Software applications.

23. A software application for use with a device for evaluating the intraocular pressure of a patient's eye, wherein the device is (a) Wearable contact lenses and (b) At least one cantilever sensor attached to the contact lens, the cantilever sensor being configured to measure the elasticity of the cornea of ​​the patient's eye and / or the IOP of the patient's eye, Includes, The contact lens is configured such that the at least one cantilever sensor is positioned adjacent to the surface of the cornea of ​​the patient's eye. The cantilever sensor includes a cantilever tip configured to apply force to the surface of the cornea, The software application includes a physician user interface configured to perform one or more of the following actions: (a) contacting the patient, (b) recommending a change in treatment, or (c) not making a change. Software applications.

24. A non-temporary computer-readable storage medium in which instructions are stored, wherein, when the instructions are executed, one or more processors of a computing device, Communicating with the device described in claim 1, The device described in claim 1 receives the measured elasticity value and / or the measured IOP value, The system generates a graphical user interface that includes a patient interface configured to take one or more corrective actions in response to the measured elasticity value and / or the measured IOP value exceeding a threshold, and the one or more corrective actions are (a) Contact a doctor, (b) recommend a change in treatment, (c) No changes will be made. including, Non-temporary computer-readable storage medium.

25. A non-temporary computer-readable storage medium in which instructions are stored, wherein, when the instructions are executed, one or more processors of a computing device, Communicating with the device described in claim 1, The device described in claim 1 receives the measured elasticity value and / or the measured IOP value, The system generates a graphical user interface that includes a graphical display of the measured elasticity value and / or the measured IOP value, and a physician interface, and the physician interface is: (a) Contact the patient, (b) recommend a change in treatment, (c) No changes will be made. Configured to perform one or more of the following: Non-temporary computer-readable storage medium.

26. The physician interface is configured to modify the treatment, and when the instruction is executed, it is sent to one or more processors. Receiving user input instructions to change the aforementioned treatment to a secondary treatment, To perform the aforementioned secondary treatment, a command is transmitted to the device described in claim 1, A non-temporary computer-readable storage medium according to claim 25, which enables the following:

27. A storage device for storing the device described in claim 1, wherein the storage device includes a housing for holding the device, the housing is To clean the wearable contact lens and the at least one cantilever sensor of the device, the device is stored in a cleaning solution. The device is stored in a medicinal solution, and the medicinal solution is filled into the wearable contact lens of the device while the device is stored in the housing. To supply power to charge the device and / or its battery while the device is stored in the housing, To facilitate the transmission of data from the aforementioned device to the storage device, and To facilitate the transmission of data and / or commands from an external device to the said device, A storage device configured to perform one or more of the following functions.

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