Measuring device, measuring system, information processing method, and program

Abstract

Provided are a measurement device, etc., enabling a user to easily change the time axis of a graph displaying a parameter measured using a catheter retained in the bladder.　This measurement device comprises a measurement unit that sequentially measures a parameter pertaining to urine on the basis of information obtained by a sensor that is disposed so as to be able to contact urine drained through a catheter; a display unit that displays the parameter with a graph using a time axis; and a reception unit (722) that receives a change instruction pertaining to the time axis.

Description

Technical Field

[0001] The present invention relates to a measuring device, a measuring system, an information processing method, and a program.

Background Art

[0002] In some cases, an indwelling urinary catheter may be placed in a patient who is unable to urinate on their own immediately after surgery or the like. Such a patient may develop acute kidney injury.

[0003] An oxygen measurement method using an indwelling urinary catheter equipped with an oxygen sensor has been proposed. By measuring the oxygen partial pressure in urine in real time and displaying a time-series graph or the like, signs of acute kidney injury can be detected at an early stage (Patent Document 1).

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] However, in the oxygen measurement method of Patent Document 1, the user cannot easily change the time axis of the oxygen partial pressure. Therefore, the user cannot appropriately confirm the long-term trend and short-term trend of the oxygen partial pressure change according to the situation.

[0006] In one aspect, an object is to provide a measuring device or the like in which a user can easily change the time axis of a graph displaying parameters measured using an indwelling urinary catheter.

Means for Solving the Problems

[0007] The measuring device comprises a measuring unit that sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with urine being drawn in via a catheter, a display unit that displays the parameters in a graph using a time axis, and a receiving unit that receives instructions to change the time axis. The system includes an external data acquisition unit that acquires data measured using a ventilator, an extracorporeal circulation device, a pulmonary artery catheter, or a left ventricular catheter. The display unit displays the data acquired by the external data acquisition unit along with a graph that displays the parameters. When the reception unit receives a change instruction regarding the time axis, the external data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. [Effects of the Invention]

[0008] One aspect of this is the ability to provide a measuring device that allows the user to easily change the time axis of a graph displaying parameters measured using a urinary catheter. [Brief explanation of the drawing]

[0009] [Figure 1] This is an explanatory diagram illustrating the configuration of the measurement system. [Figure 2] This is an explanatory diagram illustrating the configuration of the measurement system. [Figure 3] This is an explanatory diagram illustrating the configuration of a fluorescence measuring instrument. [Figure 4] This is an explanatory diagram illustrating the record layout of the measurement database. [Figure 5] This is a flowchart that explains the processing flow of a program. [Figure 6] This is a flowchart that explains the processing flow of a program. [Figure 7] This is an explanatory diagram showing an example of a display screen. [Figure 8] This is an explanatory diagram showing an example of a display screen. [Figure 9] This is an explanatory diagram showing an example of a display screen. [Figure 10] This is an explanatory diagram showing an example of a display screen. [Figure 11] This is an explanatory diagram showing an example of a display screen. [Figure 12] This is an explanatory diagram showing an example of a display screen. [Figure 13] This is an explanatory diagram showing a modified version of the display screen. [Figure 14] This is an explanatory diagram showing a modified version of the display screen. [Figure 15] It is an explanatory diagram showing a modified example of the display screen. [Figure 16] It is an explanatory diagram explaining a modified example of the kidney icon. [Figure 17] It is an explanatory diagram showing a modified example of the display screen. [Figure 18] It is an explanatory diagram explaining a modified example of the fluorescence measuring device. [Figure 19] It is a flowchart explaining the processing flow of the program of the modified example. [Figure 20] It is an explanatory diagram explaining the configuration of the fluorescence measuring device according to the second embodiment. [Figure 21] It is an explanatory diagram explaining a method for detecting an abnormality in the measurement result. [Figure 22] It is an explanatory diagram explaining a method for detecting an abnormality in the measurement result. [Figure 23] It is a flowchart explaining the processing flow of the program according to the second embodiment. [Figure 24] It is an explanatory diagram explaining the record layout of the index DB. [Figure 25] It is a flowchart explaining the processing flow of the program according to the third embodiment. [Figure 26] It is an explanatory diagram showing an example of the display screen according to the third embodiment. [Figure 27] It is an explanatory diagram showing an example of the display screen according to the third embodiment. [Figure 28] It is an explanatory diagram showing an example of the display screen according to the third embodiment. [Figure 29] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 30] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 31] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 32] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 33] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 34] It is an explanatory diagram showing an example of the display screen according to the fourth embodiment. [Figure 35] This is an explanatory diagram showing an example of the display screen of Embodiment 4. [Figure 36] This is an explanatory diagram illustrating the configuration of the fluorescence measuring instrument in Embodiment 5. [Figure 37] This is an explanatory diagram illustrating the configuration of the measuring device in Embodiment 6. [Figure 38] This is a functional block diagram of the measurement system of Embodiment 7. [Modes for carrying out the invention]

[0010] [Embodiment 1] Figure 1 is an explanatory diagram illustrating the configuration of the measurement system 10. The measurement system 10 includes a urinary catheter 15, a urine collection bag 17, and a measuring device 30. The measuring device 30 is connected via a network such as a Hospital Information System (HIS) or Electric Medical Record (EMR) to various devices such as a vital signs measuring device 191, a ventilator 192, an extracorporeal circulation device 193, a pulmonary artery (PA) catheter 194, a left ventricular catheter 195, a drug administration device 196, or a barometer 197. The measuring device 30 and the other devices may be directly connected without a network.

[0011] The indwelling bladder catheter 15 includes a shaft 153 having a side hole 151 and a balloon 152 at its tip, and a urination funnel 154 connected to one end of the shaft 153. The urine collection bag 17 includes a urine collection tube 172 and a bag 171 connected to one end of the urine collection tube 172. The other end of the urine collection tube 172 is connected to the urination funnel 154. The indwelling bladder catheter 15 may be supplied in a so-called integrated form, in which it is inseparably connected to the urine collection bag 17.

[0012] Figure 2 is an explanatory diagram illustrating the configuration of the measurement system 10. The measurement system 10 includes a measuring device 30 and a sensor 38. In this embodiment, the sensor 38 includes a fluorescence sensor 381, a temperature sensor 388, and a flow sensor 389. Each sensor 38 is attached to a urinary catheter 15 or a urine collection bag 17.

[0013] The fluorescent sensor 381 includes a phosphor 39 positioned to be in contact with the urine flowing through the channel from the side hole 151 to the bag 171, and optical components such as lenses and filters (not shown). The measurement system 10 may also include sensors 38 other than the fluorescent sensor 381, temperature sensor 388, and flow sensor 389. The measurement system 10 may also include multiple sensors 38 of the same type.

[0014] The measuring device 30 includes a control unit 31, a main memory 32, an auxiliary memory 33, a communication unit 34, a touch panel 35, a temperature measuring instrument 368, a temperature sensor connector 378, a flow rate measuring instrument 369, a flow rate sensor connector 379, a fluorescence measuring instrument 40, a first connector 371, and a bus.

[0015] The control unit 31 is an arithmetic control device that executes the program of this embodiment. The control unit 31 uses one or more CPUs (Central Processing Units), GPUs (Graphics Processing Units), or multi-core CPUs, etc. The control unit 31 is connected to each hardware component of the measuring device 30 via a bus.

[0016] The main memory 32 is a storage device such as SRAM (Static Random Access Memory), DRAM (Dynamic Random Access Memory), or flash memory. The main memory 32 temporarily stores information necessary during processing performed by the control unit 31 and the program currently being executed by the control unit 31.

[0017] The auxiliary storage device 33 is a storage device such as SRAM, flash memory, hard disk, or magnetic tape. The auxiliary storage device 33 stores the measurement value DB 51, the program to be executed by the control unit 31, and various data necessary for the execution of the program. The communication unit 34 is an interface for communication between the measuring device 30 and a network or other devices. The measurement value DB 51 may also be recorded in an external mass storage device connected to the measuring device 30.

[0018] The touch panel 35 includes a display unit 351, for example, using a liquid crystal display panel or an organic EL (electro-luminescence) panel, and an input unit 352 stacked on the display unit 351. The touch panel 35 is mounted on the housing of the measuring device 30, as shown in Figure 1. As illustrated in Figure 1, the touch panel 35 displays a graph showing various parameters measured using the sensor 38 in time series.

[0019] The touch panel 35 and the measuring device 30 may be separate entities. For example, the screen of a device such as a vital signs measuring device 191 may also serve as the touch panel 35 of the measuring device 30. Instead of the touch panel 35, a combination of a display device using a liquid crystal display panel or an organic EL panel, and an input device such as a mouse, keyboard, or voice input device may be used.

[0020] The first connector 371 is an optical connector. An optical fiber 41 is connected between the first connector 371 and the phosphor 39. The phosphor 39 and the optical fiber 41 may be permanently connected or may be detachably connected by an optical connector or the like.

[0021] The temperature sensor connector 378 is a connector to which the cable connected to the temperature sensor 388 is connected. The flow sensor connector 379 is a connector to which the cable connected to the flow sensor 389 is connected. The temperature sensor 388 and the cable, and the flow sensor 389 and the cable may be connected permanently or detachably by connectors or the like. The fluorescence meter 40 and the first connector 371 are connected by a light guide path 45. Details of the fluorescence meter 40 will be described later.

[0022] The temperature measuring device 368 is connected to the temperature sensor 388 via the temperature sensor connector 378. In this embodiment, the temperature sensor 388 is a thermocouple with a temperature-measuring junction located near the side hole 151. The temperature measuring device 368 measures the temperature based on the thermoelectric voltage generated in the thermocouple and outputs it to the bus in real time. Since temperature measurement using thermocouples has been performed conventionally, a detailed explanation will be omitted. In the following description, the temperature measured by the temperature measuring device 368 will be referred to as the bladder temperature.

[0023] For example, a temperature sensing junction may be located in the middle of the shaft 153, in the urination funnel 154, or in the urine collection bag 17. In this case, the thermometer 368 measures the temperature of the urine at the location of the temperature sensing junction instead of the bladder temperature. In the following description, the temperature of the urine will be referred to as urine temperature.

[0024] The temperature sensor 388 is not limited to a thermocouple. Any sensor 38 that can be used for temperature measurement can be used as the temperature sensor 388. For example, a thermistor, resistance thermometer, IC temperature sensor, fluorescent dye, etc. can be used as the temperature sensor 388. When using multiple temperature sensors 388, they may be the same type of temperature sensor 388 or different types of temperature sensors 388.

[0025] The flow meter 369 is connected to the flow sensor 389 via the flow sensor connector 379. For example, the flow sensor 389 is an optical flow sensor that transmits and receives laser Doppler signals to and from urine, and the flow meter 369 is an optical flow meter. The flow meter 369 measures the flow rate of urine and outputs it to the bus in real time. In the following description, the flow rate of urine will be referred to as urine flow rate. The flow meter 369 is an example of a flow measurement unit.

[0026] The principle of flow measurement is not limited to optical methods. Therefore, the temperature sensor 388 is not limited to an optical flow sensor. The temperature sensor 388 may be, for example, an ultrasonic flow sensor or a thermal flow sensor.

[0027] The flow meter 369 may measure the urine flow rate by obtaining the change in the weight of the bag 171 over time from a scale that measures the weight of the bag 171. A structure that drops liquid in droplets and a sensor 38 that counts the droplets may be placed in the flow path of the urine collection bag 17. The flow meter 369 can measure the flow rate based on the number of droplets and the volume of the droplets.

[0028] The optical fiber 41 connecting the sensor 38 and the measuring device 30, and the wire material such as an electric wire, are not limited to being connected to the independent first connector 371, temperature sensor connector 378, and flow sensor connector 379, as illustrated in Figure 2. Instead of the first connector 371, temperature sensor connector 378, and flow sensor connector 379, a composite connector that integrates the functions of these three connectors may be provided.

[0029] If a composite connector is provided, a composite cable may be used, which bundles the optical fiber 41 with a wire such as an electric wire. In other words, the urinary catheter 15 and the urine collection bag 17 and the measuring device 30 may appear to be connected by a single cable and a single composite connector.

[0030] The temperature sensor connector 378 and the temperature sensor 388 are configured as a single unit, and the measured temperature may be transmitted wirelessly to the measuring device 30. Similarly, the flow sensor 389 and the flow meter 369 are configured as a single unit, and the measured flow rate may be transmitted wirelessly to the measuring device 30.

[0031] Figure 3 is an explanatory diagram illustrating the configuration of the fluorescence meter 40. The fluorescence meter 40 comprises a light source 42, a beam splitter 43, a fluorescence detection unit 46, and a calculation unit 47. The light source 42 and the beam splitter 43, the beam splitter 43 and the fluorescence detection unit 46, and the beam splitter 43 and the first connector 371 are connected by optical guide paths 45. An optical fiber connector 411, which can be connected to the first connector 371, is provided at the end of the optical fiber 41.

[0032] The light source 42 is, for example, an LED (light-emitting diode) or a laser diode. The light source 42 irradiates the phosphor 39 with excitation light. The light emitted by the light source 42 contains almost no wavelengths of fluorescence emitted by the phosphor 39.

[0033] If the light emitted by the light source 42 includes the wavelength of fluorescence emitted by the phosphor 39, or if it is desirable to make the excitation light wavelength the precise excitation wavelength, an optical filter may be placed in the optical path of the optical guide path 45.

[0034] The excitation light emitted from the light source 42 irradiates the phosphor 39 via the light guide path 45, beam splitter 43, and optical fiber 41. When the phosphor 39 is in contact with urine, fluorescence is emitted according to the partial pressure or oxygen concentration of oxygen in the urine. In the following description, the partial pressure of oxygen in urine will be referred to as the partial pressure of oxygen in urine.

[0035] Fluorescence is incident on the beam splitter 43 via the optical fiber 41 and the light guide path 45. The fluorescence is then incident on the light guide path 45 connected to the fluorescence detection unit 46 by the beam splitter 43. The fluorescence detection unit 46 is equipped with a photoelectric conversion element, such as a photodiode, and converts the fluorescence into an electrical signal. The calculation unit 47 analyzes the electrical signal and outputs the partial pressure of oxygen in the urine to the bus in real time. The calculation unit 47 is an example of a measurement unit that sequentially measures parameters related to urine based on information obtained by the sensor 38.

[0036] The first connector 371, temperature sensor connector 378, and flow sensor connector 379 function as a sensor data acquisition unit that acquires sensor data from sensor 38. The calculation unit 47, temperature measuring instrument 368, and flow measuring instrument 369 function as a calculation unit that sequentially calculates parameters related to urine using the sensor data.

[0037] Figure 4 is an explanatory diagram illustrating the record layout of the measurement data DB51. The measurement data DB51 is a database that records the bed ID, patient ID, measurement item, measurement date and time, and measurement data in association with each other.

[0038] The measurement data DB51 has a bed ID field, a patient ID field, a measurement item field, a measurement date and time field, and a measurement data field. The bed ID field records the bed ID uniquely assigned to the bed. The patient ID field records the patient ID uniquely assigned to the patient.

[0039] The measurement item field records the measurement item. Examples of measurement items include "oxygen partial pressure," "temperature," and "flow rate." The measurement date and time field records the measurement date and time. The measurement data field records the measurement data measured using the sensor 38.

[0040] In Figure 4, the measurement date and time field and the measurement data field record the date and time and the partial pressure of oxygen in urine measured by the fluorescence detector 40, respectively. When the measurement item field is "temperature", the measurement date and time field and the measurement data field record the date and time and the intrabladder temperature measured by the thermometer 368, respectively.

[0041] When the measurement item field is "flow rate," the measurement date and time field and measurement data field record the date and time and the amount of urine flow rate measured by the flow rate meter 369, respectively. The measurement value DB 51 has one record for each measurement of a single item.

[0042] As explained above, each measurement item, measurement date and time, and measurement data are recorded in association with each other. Therefore, even if the measurement interval differs for each measurement item, the control unit 31 can record the measurement data in the measurement value DB 51.

[0043] An overview of how to use the measurement system 10 of this embodiment will be described. A user, such as a doctor, inserts the shaft 153 into the patient's urethra. With the tip of the shaft 153 inside the bladder, the user inflates the balloon 152. The balloon 152 shown in Figure 1 is in an inflated state. By inflating the balloon 152, the shaft 153 becomes unable to be removed from the urethra. The patient's urine is drawn in through a channel connecting the side hole 151 and the bag 171 and collected in the bag 171.

[0044] The fluorescence meter 40 outputs the partial pressure of oxygen in the urine, the temperature meter 368 outputs the bladder temperature, and the flow rate meter 369 outputs the urine flow rate to the bus. Partial pressure of oxygen in the urine, urine flow rate, and bladder temperature are examples of parameters related to urine. The control unit 31 records each data in the measurement value DB 51 in association with the measurement date and time, and displays it on the touch panel 35 in the form of a graph using a time axis, as shown in Figure 1. In the graph in Figure 1, the horizontal axis is time, and the vertical axis is the partial pressure of oxygen in the urine, urine flow rate, and bladder temperature.

[0045] The user can easily understand the changes in parameters through the graph displayed on the touch panel 35. For example, if the user wants to check a long-term trend or check changes in the short term, they can easily change the horizontal axis of the graph by operating the touch panel 35. Details of the screen display and user operations will be described later.

[0046] Figure 5 is a flowchart illustrating the program's processing flow. The program shown in Figure 5 is activated when the control unit 31 instructs the user to start measurement.

[0047] The control unit 31 acquires data output to the bus from the fluorescence meter 40, temperature meter 368, or flow rate meter 369 (step S501). The control unit 31 creates a new record in the measurement value DB 51 and records the acquired data (step S502). The control unit 31 determines whether the acquired data indicates an abnormal value (step S503).

[0048] The criteria for determining whether a value is abnormal are predetermined for each measurement item. For example, the control unit 31 determines that a value is abnormal if any of the data falls outside a predetermined normal range. The control unit 31 may also determine whether a value is abnormal based on the rate of change of each measurement item. The control unit 31 may also determine whether a value is abnormal based on a combination of multiple measurement items.

[0049] If the control unit 31 determines that an abnormal value has been detected (YES in step S503), it notifies the system that an abnormal value has been detected (step S504). The notification is made, for example, by displaying it on the touch panel 35 or by outputting an audio message from the measuring device 30. The control unit 31 may also send the notification to the nurse station or electronic medical record system via a network such as HIS.

[0050] If it is determined that the value is not abnormal (NO in step S503), or after the completion of step S504, the control unit 31 determines whether or not to terminate the process (step S505). For example, if the control unit 31 receives a termination instruction from the user, it determines to terminate the process.

[0051] If it is determined that the process should not be terminated (NO in step S505), the control unit 31 returns to step S501. If it is determined that the process should be terminated (YES in step S505), the control unit 31 terminates the process.

[0052] Between step S501 and step S502, the control unit 31 may correct the partial pressure of oxygen in the urine calculated by the calculation unit 47 based on atmospheric pressure, bladder pressure, temperature, or the chloride concentration of the urine. If so, the control unit 31 implements the function of a correction unit that corrects the partial pressure of oxygen in the urine.

[0053] Figure 6 is a flowchart illustrating the program's processing flow. The control unit 31 executes the program shown in Figure 6 in parallel with the program described using Figure 5.

[0054] The control unit 31 displays a graph on the touch panel 35 (step S521). At step S521, only the graph frame, including the vertical axis and horizontal axis, is displayed. Initial settings for the vertical axis, horizontal axis, and display items are stored in advance in the main memory 32 or auxiliary memory 33.

[0055] The control unit 31 reads data from the measurement value DB 51 and updates the graph (step S522). While the program in Figure 6 is running, data is sequentially added to the measurement value DB 51 by the program described using Figure 5.

[0056] The control unit 31 determines whether or not it has received an operation from the user (step S523). If it determines that it has not received an operation (NO in step S523), the control unit 31 returns to step S522. If it determines that it has received an operation (YES in step S523), the control unit 31 determines whether or not the operation is an operation that changes the time axis (step S524). Specific examples of operations that change the time axis will be described later.

[0057] If the control unit 31 determines that the operation involves changing the time axis (YES in step S524), it changes the time axis setting (step S525). After that, the control unit 31 returns to step S522. In the subsequent step S522, the control unit 31 displays the graph with the changed time axis.

[0058] If it is determined that the operation does not change the time axis (NO in step S524), the control unit 31 determines whether or not the operation terminates the program (step S526). If it is determined that the operation terminates the program (YES in step S526), ​​the control unit 31 terminates the process. The control unit 31 may terminate the processing of the program described using Figure 5, as well as the program shown in Figure 6.

[0059] If the control unit 31 determines that the operation is not to terminate the program (NO in step S526), ​​it displays a menu screen on the touch panel 35 (step S527). The control unit 31 accepts user input via the touch panel 35 (step S528). After that, the control unit 31 returns to step S522.

[0060] Figures 7 to 12 are explanatory diagrams illustrating examples of display screens. Figure 7 shows an example of a screen displayed on the touch panel 35 by the control unit 31 in step S521. The screen displays, from the upper left to the lower right, a menu display button 721, a patient information field 731, a date and time field 732, an oxygen partial pressure field 712, a temperature field 713, a urine flow rate field 714, a graph field 711, a time axis change button 722, and a notification field 74.

[0061] The menu display button 721 is a button that accepts instructions to transition to the menu screen, which will be described next. The patient information field 731 displays the patient ID, patient's name, age, diagnosis, and room number.

[0062] The date and time column 732 displays the current date and time. The oxygen partial pressure column 712 displays the latest measurement of urinary oxygen partial pressure. The temperature column 713 displays the latest measurement of bladder temperature. The urine flow rate column 714 displays the latest measurement of urine flow rate.

[0063] Graph 711 displays a graph showing the measured values ​​recorded in the measurement database DB51 in chronological order. As mentioned above, the horizontal axis of the graph represents time, and the vertical axis represents urinary oxygen partial pressure, urinary flow rate, and bladder temperature. In Figure 7, the scale of the vertical axis is not shown.

[0064] The solid line in the graph represents the partial pressure of oxygen in urine. The frame surrounding the oxygen partial pressure column 712 is also a solid line. The dashed line in the graph represents the temperature inside the bladder. The frame surrounding the temperature column 713 is also a dashed line. The dotted line in the graph represents the urine flow rate. The frame surrounding the urine flow rate column 714 is also a dotted line. The line types of the frames surrounding the oxygen partial pressure column 712, the temperature column 713, and the urine flow rate column 714 serve as a legend, allowing the user to easily understand what each graph represents. The numbers representing oxygen partial pressure, bladder temperature, and urine flow rate may be the same as the colors of the graphs. The partial pressure of oxygen in urine may also be displayed using the oxygen concentration in the urine. The control unit 31 converts from oxygen partial pressure to oxygen concentration based on simultaneously measured data such as temperature and atmospheric pressure.

[0065] The time axis change button 722 is a button that accepts a change to the time axis. In Figure 7, "5 minutes" is selected, and each division in the graph column 711 represents 5 minutes. For example, if the user selects "1 minute", the control unit 31 changes each division in the graph column 711 to 1 minute. The time axis change button 722 is an example of a reception unit that accepts instructions to change the time axis.

[0066] A slider may be displayed instead of the time axis change button 722. When the user moves the slider, the control unit 31 changes the time axis of the graph field 711. The control unit 31 may also change the time axis when the user taps the graph field 711. Any other user interface can be used instead of the time axis change button 722.

[0067] In the notification section 74 of Figure 7, the notification "Your urine volume is low. Please check" is displayed. This notification was output by the control unit 31 in step S504 when it was determined in step S503 of the flowchart explained using Figure 5 that the urine flow rate was below the threshold.

[0068] Notification area 74 may display notifications based on data measured by the measuring device 30, such as partial pressure of oxygen in urine or the temperature of urine. Notification area 74 may also display notifications based on information obtained from other devices, such as a vital signs measuring device 191 or a ventilator 192, and data analyzed by the measuring device 30.

[0069] The control unit 31 may also display the moving average of the measurement data for each measurement item in the graph section 711. When noise due to patient movement, etc., is easily superimposed on the measurement data, displaying the moving average allows the user to appropriately understand the patient's condition.

[0070] Figure 8 shows an example of a menu screen displayed by the control unit 31 when the user selects the menu display button 721. Menu selection buttons 724 for "Data Display," "Data List Confirmation," "Patient Information Confirmation," "Patient Information Input," "Settings / Data Output," "Measurement Condition Settings," "Device Status Confirmation," and "Other" are displayed. The control unit 31 accepts the user's selection of a menu selection button 724. If the user selects the "Data Display" menu selection button 724, the control unit 31 returns to the screen described using Figure 7.

[0071] Figure 9 shows an example of the screen displayed by the control unit 31 when the "Confirm Data List" menu selection button 724 is selected. The screen displays the menu display button 721, patient information field 731, date and time field 732, oxygen partial pressure field 712, urine flow rate field 714, and temperature field 713 from the upper left to the lower right.

[0072] In Figure 9, the patient information section 731 displays the patient ID, patient's name, age, diagnosis, and room number, as well as height and weight. Other items are the same as those described in Figure 7, so their explanation is omitted. The same applies to subsequent screen descriptions.

[0073] Figure 10 shows an example of the screen displayed by the control unit 31 when the "Patient Information Confirmation" menu selection button 724 is selected. The screen displays the menu display button 721, patient information field 731, attending physician field 733, entry time field 734, and measurement information field 735 from top to bottom.

[0074] The attending physician section 733 displays the name of the attending physician responsible for the patient. A communication button for contacting the attending physician may be located near the attending physician section 733. For example, the attending physician's contact information, such as a mobile phone number, may be displayed near the attending physician section 733.

[0075] The "Time of Entry" column 734 displays the time the patient entered the room indicated in the "Patient Information" column 731. The "Measurement Information" column 735 displays the time when measurement was started using the measuring device 30.

[0076] Figure 11 shows an example of the screen displayed by the control unit 31 when the user selects the "Patient Information Input" menu button 724. At the top of the screen, the menu display button 721, the ID reading button 725, and the patient information acquisition button 726 are displayed. The ID reading button 725 is used to read the patient ID written on a wristband or other item worn by the patient, for example, using a barcode reader (not shown in the figure). The black circle to the left of the ID reading button 725 indicates that the patient ID reading is complete. The user can use the ID reading button 725 to read the patient ID again.

[0077] The control unit 31 may accept patient ID input via an input device such as a keyboard. The procedure for reading patient IDs varies depending on the medical institution. It is desirable that the measuring device 30 be able to configure processing according to the procedures of each medical institution.

[0078] When the patient information acquisition button 726 is selected, the control unit 31 uses the patient ID as a key to acquire patient data such as the patient's name from an electronic medical record (not shown in the figure), thereby synchronizing the information recorded in the control unit 31 with the information recorded in the electronic medical record. In Figure 11, the control unit 31 displays the patient's height, weight, age, gender, and disease name. The control unit 31 may accept modifications to these items via the screen shown in Figure 11. At the bottom of the screen shown in Figure 11, the connected device selection button 727 is displayed.

[0079] The items shown in Figure 11 are examples of patient data. In addition to height, weight, age, sex, and disease name as exemplified in Figure 11, patient data may also include patient background factors such as BMI (Body Mass Index) calculated from height and weight. Patient data may also include data on various laboratory items such as serum creatinine levels and urea nitrogen levels.

[0080] Through the weight item on the screen in Figure 11, the control unit 31 implements the function of a weight acquisition unit that acquires the patient's weight. The weight acquisition unit is an example of a patient information acquisition unit. The control unit 31 may acquire the patient's weight via a weighing scale with communication capabilities. The control unit 31 may acquire patient data from a system such as HIS or EMR.

[0081] Figure 12 shows an example of the screen displayed by the control unit 31 when the "Measurement Conditions Setting" menu selection button 724 or the connected device selection button 727 is selected. The menu display button 721 is displayed in the upper left corner of the screen.

[0082] The control unit 31 accepts settings for measurement conditions such as the units for urinary oxygen partial pressure, urine flow rate, and bladder temperature, measurement frequency, and intervals used when calculating moving averages. Furthermore, the control unit 31 accepts settings for whether or not to calculate renal indicators, the graph format, and the screen display color. Renal indicators will be described later.

[0083] Users are not required to be able to change settings such as measurement frequency and moving average. In such cases, the pull-down menu indicated by an inverted triangle to the right of the setting value for each item will not be displayed. The control unit 31 may accept changes to settings such as measurement frequency and moving average only when the measuring device 30 is being used by a specific user, such as the person in charge of managing the measuring device 30.

[0084] Figures 13 to 15 are explanatory diagrams showing modified displays. The control unit 31 may display the screens shown in Figures 13 to 15 instead of the screen described using Figure 7. The user may be able to switch the display format of the screen.

[0085] In the screen shown in Figure 13, the patient information field 731 and the time axis change button 722 are not displayed. Because fewer items are displayed, the screen is simpler, allowing the user to quickly find the necessary information.

[0086] The control unit 31 changes the time axis when it receives, for example, a tap or flick operation near the horizontal axis of the graph column 711. The user may configure how the time axis is changed in response to different user operations. The control unit 31 may also receive time axis change instructions from the user via voice input.

[0087] In the screen shown in Figure 14, the oxygen partial pressure column 712, the urine flow rate column 714, and the temperature column 713 are arranged in a single vertical column using characters of the same size. The display screen is even simpler than that in Figure 13.

[0088] In the screen shown in Figure 15, the oxygen partial pressure column 712, the temperature column 713, and the urine flow rate column 714 are displayed around a kidney icon 718 which schematically represents the shape of the kidney and bladder.

[0089] Graph 711 displays approximately two weeks' worth of data. The urinary oxygen partial pressure (shown by a solid line), bladder temperature (shown by a dashed line), and urine flow rate (shown by a dotted line) are all displayed as moving averages over several days. Urine flow rate is also displayed in the form of a candlestick chart, showing the lowest, highest, first, and last values ​​of the day. Since candlestick charts have been used for a long time to display stock price movements, a detailed explanation will be omitted.

[0090] Candlestick charts may also be displayed for urinary oxygen partial pressure (shown with a solid line) and bladder temperature (shown with a dashed line). It is desirable that users can easily switch the display of candlestick charts on or off. Candlestick charts allow users to easily grasp the changing trends of each measurement data.

[0091] The display in graph column 711 is illustrative. The items displayed in graph column 711 are not limited to the three items of urinary oxygen partial pressure, bladder temperature, and urine flow rate. It is desirable that users be able to appropriately set the items and display format shown in graph column 711.

[0092] The control unit 31 may change the display to one that is more likely to attract the user's attention, such as displaying the kidney icon 718 in red or making it blink, if there are items that show abnormal values.

[0093] Figure 16 is an explanatory diagram illustrating a modified version of the kidney icon 718. The control unit 31 selects and displays the kidney icon 718 according to the urine flow rate. Kidney icon 718 No. 1 is used when the urine flow rate is very low, and No. 4 is used when the urine flow rate is very high. The control unit 31 may also display the part of the urine dripping from the bladder with animation. Not only medical professionals but also visitors and the patients themselves can intuitively understand the changes in urine flow rate.

[0094] Figure 17 is an explanatory diagram showing a modified display screen. Figure 17 is an example screen for managing multiple devices with a single device. Data measured by multiple measurement systems 10 are displayed in a list format, known as tiles. Users such as nurses can view information for many patients at once. In this case, the status of each patient can be grasped at a glance by representing the status of measurement (in progress, measurement stopped, etc.) with colors and border line types.

[0095] Figure 18 is an explanatory diagram illustrating a modified example of the fluorescence measuring instrument 40. In this modified example, the light source 42 and the first connector 371, and the fluorescence detection unit 46 and the first connector 371 are directly connected by a light guide path 45. The optical fiber connector 411 and the phosphor 39 are connected by an irradiation fiber 412 and a light receiving fiber 413.

[0096] The illumination fiber 412 is connected to the light guide path 45 connected to the light source 42 via the optical fiber connector 411 and the first connector 371, and the light receiving fiber 413 is connected to the light guide path 45 connected to the fluorescence detection unit 46.

[0097] Excitation light emitted from the light source 42 irradiates the phosphor 39 via the light guide path 45 and the irradiation fiber 412. When the phosphor 39 comes into contact with urine, fluorescence is emitted according to the concentration of the target substance in the urine. In the case of fluorescence using oxygen as a quencher, fluorescence is emitted according to the oxygen concentration and oxygen partial pressure.

[0098] Fluorescence is incident on the fluorescence detection unit 46 via the light-receiving fiber 413 and the light guide path 45. The fluorescence detection unit 46 converts the fluorescence into an electrical signal. The calculation unit 47 analyzes the electrical signal and outputs the partial pressure of oxygen in urine or the oxygen concentration in urine to the bus in real time. According to this modified example, a measurement system 10 can be provided that does not use the beam splitter 43.

[0099] The illumination fiber 412 and the light-receiving fiber 413 may be bundled together to form an optical fiber 41. The optical fiber 41 is a bundle of thin fiber strands. The number of fiber strands contained in the illumination fiber 412 and the number of fiber strands contained in the light-receiving fiber 413 may be the same or different. In a fluorescence sensor 38, since the fluorescence intensity is small compared to the excitation light intensity, it is desirable to increase the number of fiber strands contained in the light-receiving fiber 413 to improve the light-receiving efficiency.

[0100] The optical fiber connector 411 and the first connector 371 may be separated into those for excitation light irradiation and those for fluorescence reception, respectively. In this case, the optical fiber 41 is a single fiber on the phosphor 39 side and branches into two on the optical fiber connector 411 side, with optical fiber connectors 411 attached to each end. A coupling may be provided at the branching point of the optical fiber 41.

[0101] Figure 19 is a flowchart illustrating the processing flow of a modified program. The program shown in Figure 19 is designed to allow the use of sensor-specific values ​​defined for each sensor 38.

[0102] Sensor eigenvalues ​​are values ​​acquired for each sensor 38 during its manufacture and are used for calculating or correcting measurement results. These sensor eigenvalues ​​are, for example, indicated on the sensor 38's packaging. Possible values ​​used include the slope of a regression line measured under specific conditions, the phase angle corresponding to oxygen concentration, and values ​​related to decay time or intensity. Corrections are made for temperature, pressure, and chloride ions; these may be obtained using actual values, or previously published mathematical formulas used for calibration may be employed. Furthermore, corrections can be performed using numerical values ​​manually entered by the user to obtain the necessary information.

[0103] The control unit 31 receives input of the sensor type via the input unit 352 (step S541). The control unit 31 receives input of the sensor eigenvalue via the input unit 352 (step S542). In step S542, the control unit 31 realizes the function of the sensor eigenvalue acquisition unit, which acquires the sensor eigenvalue.

[0104] The control unit 31 sets the sensor eigenvalue received in step S542 to the measuring instrument corresponding to the sensor type received in step S541 (step S543). Thereafter, the measuring instrument outputs measurement data measured using the sensor eigenvalue. The measuring instrument implements the function of a calibration unit that performs calibration of the sensor 38 based on the sensor eigenvalue.

[0105] The fluorescence meter 40 may also have a function for calibrating the sensor 38. For example, calibration environments with known target concentrations are prepared for two target concentrations. By measuring the sensor values ​​output from each sensor 38 in both environments, the sensor 38 can be calibrated. The calibration method for the sensor 38 is determined appropriately for each measurement system 10.

[0106] According to this embodiment, a measurement system 10 can be provided that displays parameters measured using a urinary catheter 15 in a graph using a time axis. According to this embodiment, a measurement system 10 can be provided that allows the user to easily change the time axis of the displayed graph.

[0107] The phosphor 39 may emit fluorescence in response to carbon dioxide in urine. By analyzing the fluorescence properties, the partial pressure of carbon dioxide in urine can be measured in real time. Examples of fluorescence properties used here include fluorescence intensity, decay time, and phase angle. The fluorescence emission state of the phosphor 39 may change depending on the hydrogen ion concentration of the urine. By analyzing the fluorescence properties, the hydrogen ion concentration of the urine, i.e., pH (potential of hydrogen), can be measured in real time. Examples of fluorescence properties used here include intensity, decay time, and phase angle.

[0108] The phosphor 39 may emit fluorescence in response to the concentration of any component in the urine, such as potassium, sodium, creatinine, or urea nitrogen. By analyzing the fluorescence characteristics, the concentration of components in the urine, creatinine levels, or urea nitrogen levels can be measured in real time. In addition, a phosphor 39 that emits fluorescence in response to any component in the urine may be used.

[0109] The phosphor 39 may change its luminescence state depending on the temperature. By analyzing the fluorescence properties, the temperature of the urine can be measured in real time. In other words, the phosphor 39 may be used in the temperature sensor 388.

[0110] The phosphor 39 may change its luminescence state depending on the flow rate of the urine it comes into contact with. By analyzing the fluorescence, the urine flow rate can be measured in real time. In other words, the phosphor 39 may be used in the flow sensor 389.

[0111] The phosphor 39 may change its luminescence state depending on the pressure. For example, by placing the phosphor 39 inside the bladder and analyzing the fluorescence, the bladder pressure can be measured in real time. In other words, the phosphor 39 may be used as a bladder pressure sensor.

[0112] The measurement system 10 may include a sensor 38 capable of measuring the perfusion state around the urethra. An example of such a sensor 38 is a sensor 38 that analyzes the absorption wavelength specific to oxygenated hemoglobin. The measurement system 10 may also include two or more fluorescent sensors 381 having a phosphor 39 that reacts to oxygen in urine, and two or more temperature sensors 388. The fluorescent sensor 381 having a phosphor 39 that reacts to oxygen in urine is an example of the oxygen sensor in this embodiment. The measurement system 10 may also include a sensor 38 capable of measuring the blood flow velocity around the urethra.

[0113] The measuring device 30 may include a second measuring unit that measures arbitrary parameters such as urine specific gravity, bladder pressure, or perfusion state around the urethra, based on information obtained from a sensor 38 positioned in a location that does not come into contact with urine. By including the second measuring unit, a measuring device 30 can be provided that measures multiple parameters in parallel.

[0114] The measurement system 10 does not necessarily have to include a temperature sensor 388 and a temperature measuring instrument 368. The measurement system 10 does not necessarily have to include a flow sensor 389 and a flow measuring instrument 369.

[0115] [Embodiment 2] Figure 20 is an explanatory diagram illustrating the configuration of the fluorescence meter 40 of Embodiment 2. The fluorescence meter 40 of this embodiment can detect abnormalities in the measurement data of oxygen partial pressure in urine. Parts common to Embodiment 1 will not be explained.

[0116] The fluorescence meter 40 of this embodiment comprises one light source 42 and two fluorescence detection units 46, a first fluorescence detection unit 461 and a second fluorescence detection unit 462. A first calculation unit 471 is connected to the first fluorescence detection unit 461. The first fluorescence detection unit 461 is connected to a first connector 371 via a light guide path 45. A second calculation unit 472 is connected to the second fluorescence detection unit 462. The second fluorescence detection unit 462 is connected to a second connector 372 via a light guide path 45. The light source 42 is connected to a third connector 373 via a light guide path 45.

[0117] Two fluorescent sensors 381 are connected to a fluorescence measuring instrument 40. One fluorescent sensor 381 has a first phosphor 391. The other fluorescent sensor 381 has a second phosphor 392. Both the first phosphor 391 and the second phosphor 392 are phosphors 39 made of the same fluorescent material that emits fluorescence in response to the partial pressure of oxygen in urine.

[0118] A fluorescent sensor 381 having a first phosphor 391 is positioned near the side hole 151 and comes into contact with the urine in the bladder. This fluorescent sensor 381 is an example of a first sensor positioned inside the bladder. A fluorescent sensor 381 having a second phosphor 392 is positioned, for example, near the urination funnel 154 or inside the bag 171, and comes into contact with the urine that has been drawn out of the patient's body. This fluorescent sensor 381 is an example of a second sensor positioned outside the body.

[0119] The first phosphor 391 is connected to the optical fiber connector 411 via a light-receiving fiber 413. The second phosphor 392 is connected to the optical fiber connector 411 via a light-receiving fiber 413. Both the first phosphor 391 and the second phosphor 392 are connected to the same optical fiber connector 411 via a bifurcated irradiation fiber 412.

[0120] Excitation light emitted from the light source 42 irradiates the first phosphor 391 and the second phosphor 392 via the light guide path 45 and the irradiation fiber 412. When the first phosphor 391 and the second phosphor 392 come into contact with urine, fluorescence is emitted according to the partial pressure or oxygen concentration of oxygen in the urine.

[0121] The fluorescence emitted by the first phosphor 391 is incident on the first fluorescence detection unit 461 via the light-receiving fiber 413 and the light guide path 45. The first fluorescence detection unit 461 converts the fluorescence into an electrical signal. The first calculation unit 471 analyzes the electrical signal and outputs the partial pressure of oxygen in urine or oxygen concentration to the bus in real time.

[0122] The fluorescence emitted by the second phosphor 392 is incident on the second fluorescence detection unit 462 via the light-receiving fiber 413 and the light guide path 45. The second fluorescence detection unit 462 converts the fluorescence into an electrical signal. The second calculation unit 472 analyzes the electrical signal and outputs the partial pressure of oxygen in urine or oxygen concentration to the bus in real time.

[0123] Figures 21 and 22 are explanatory diagrams illustrating a method for detecting abnormalities in measurement results. Figure 21 is a schematic graph showing the time changes in urinary oxygen partial pressure in the bladder, urinary oxygen partial pressure outside the body, and urine flow rate. The horizontal axis of Figure 21 represents time. The vertical axis of Figure 21 represents urinary oxygen partial pressure and urine flow rate. Since this is a schematic diagram, the units for each axis are omitted.

[0124] The thick solid line shows the time change in urinary oxygen partial pressure measured in the bladder. The thin solid line shows the time change in urinary oxygen partial pressure measured outside the body. The dashed line shows the time change in urine flow rate. From time t1 to time t2, and from time t3 onward, the trends in urinary oxygen partial pressure in the bladder and urinary oxygen partial pressure outside the body are almost identical. However, from time t2 to time t3, urinary oxygen partial pressure is decreasing, while extravesical oxygen partial pressure is increasing. During this period, urine flow rate is low.

[0125] For example, oxygen may be consumed by substances in the urine, causing the partial pressure of oxygen in the urine to decrease. This phenomenon is more likely to occur in urine that has been left standing for a while. For example, if the urine is in an environment where oxygen from the atmosphere dissolves before it is measured, the partial pressure of oxygen in the urine may increase. In either case, the data that should be measured is not being measured. Therefore, as shown in Figure 21, if the trend of the measurement results differs depending on where the sensor 38 is placed, the reliability of the measurement data is low.

[0126] Figure 22 is a schematic graph illustrating the relationship between urinary oxygen partial pressure measured in the bladder and urinary oxygen partial pressure measured outside the body. The vertical axis represents the urinary oxygen partial pressure in the bladder measured using the first phosphor 391. The horizontal axis represents the urinary oxygen partial pressure outside the body measured using the second phosphor 392. As this is a schematic diagram, the units for each axis are omitted.

[0127] Each black circle represents measurement data taken approximately simultaneously. The thin solid line represents a regression line calculated, for example, by the least squares method. In Figure 22, the trends in urinary oxygen partial pressure in the bladder and urinary oxygen partial pressure outside the body coincide, and the slope of the regression line is positive. If a graph similar to Figure 22 is created using data from time t2 to time t3 in Figure 21, the slope of the regression line will be negative.

[0128] The slope of the regression line calculated using several sets of measurement data from the most recent reading can be used as an indicator of the reliability of the latest urinary oxygen partial pressure. The control unit 31 may display an indicator of reliability along with both urinary oxygen partial pressures. The control unit 31 may also display an indicator of reliability along with one of the urinary oxygen partial pressures. If only one is displayed, it is desirable to display the urinary oxygen partial pressure in the bladder. The control unit 31 may change the color or font size of the urinary oxygen partial pressure in the bladder depending on the indicator. For example, if the reliability is low, the control unit 31 will display the urinary oxygen partial pressure in a lighter color or smaller font.

[0129] Figure 23 is a flowchart illustrating the processing flow of the program in Embodiment 2. The program in Figure 23 is executed in place of the program described using Figure 6.

[0130] The control unit 31 displays a graph on the touch panel 35 (step S521). The control unit 31 reads data from the measurement value DB 51 and updates the graph (step S522). The control unit 31 calculates the slope of the regression line, as explained using Figure 22, based on the most recent few data points (step S561).

[0131] The control unit 31 determines whether the slope of the regression line is negative (step S562). If it determines that it is negative (YES in step S562), the control unit 31 notifies that the reliability of the measurement value is low (step S563). The notification is made, for example, by display on the touch panel 35 or by voice output from the measuring device 30. The control unit 31 may also send the notification to the nurse station or the like via a network such as HIS.

[0132] If it is determined that the result is not negative (NO in step S562), or after the completion of step S563, the control unit 31 determines whether or not it has received an operation from the user (step S523). The subsequent processing is the same as the processing flow explained using Figure 6, so the explanation is omitted.

[0133] In step S562, if the control unit 31 detects a change in the slope of the regression line, it may proceed to step S563. This provides a measurement system 10 that can detect abnormalities in the measurement data early.

[0134] According to this embodiment, a measurement system 10 that displays the reliability of measurement data can be provided. Users can make appropriate decisions without being misled by data with low reliability. Users may take necessary measures to improve reliability, such as correcting the position of the sensor 38, if the reliability is low.

[0135] According to this embodiment, a measurement system 10 can be provided that measures the partial pressure of oxygen in urine at two locations using a single light source 42. The parameters measured at each of the two locations are not limited to the partial pressure of oxygen in urine. Any parameter may be measured at the two locations.

[0136] Different fluorescent materials may be used for the first phosphor 391 and the second phosphor 392. A measurement system 10 can be provided that acquires two types of measurement data using one light source 42. The two fluorescent sensors 381 may be placed close together or at different locations.

[0137] In this case, the excitation light emitted by the light source 42 includes both the wavelength that excites the first phosphor 391 and the wavelength that excites the second phosphor 392. If the wavelength of one excitation light and the wavelength of the other fluorescence are close together, the excitation light and fluorescence can be separated by using an appropriate optical filter.

[0138] [Embodiment 3] This embodiment relates to a measurement system 10 that displays an index calculated based on measured parameters. Parts common to Embodiment 1 will not be described.

[0139] Figure 24 is an explanatory diagram illustrating the record layout of the indicator database. The indicator database is a database that records the relationship between the bed ID, patient ID, indicator name, calculation date and time, and the indicator.

[0140] The indicator database has a bed ID field, a patient ID field, an indicator name field, a calculation date and time field, and an indicator field. The bed ID field records the bed ID uniquely assigned to the bed. The patient ID field records the patient ID uniquely assigned to the patient.

[0141] The index name field records the index name. In Figure 24, the index name is "Estimated Renal Tissue Oxygen Partial Pressure". The calculation date and time field records the date and time the index was calculated. The calculation date and time field may also record the measurement date and time of the most recently measured parameter among the multiple parameters used to calculate the index. The index field records the index calculated based on multiple parameters.

[0142] The "estimated renal tissue oxygen partial pressure" shown in Figure 24 is the partial oxygen pressure within the kidney calculated based on parameters such as the partial oxygen pressure in urine measured in the bladder, etc. The formula for calculating the estimated renal tissue oxygen partial pressure is determined in advance based on data measured in a large number of subjects or animals. The estimated renal tissue oxygen partial pressure may also be output by a machine learning model that takes the patient's attributes such as age and sex, and the measured parameters as input and outputs the estimated renal tissue oxygen partial pressure. "Estimated renal tissue oxygen partial pressure" is an example of an index calculated based on measured parameters.

[0143] The indicator may be the dissolved oxygen concentration dissolved in the urine. Since the method for calculating the dissolved oxygen concentration based on the partial pressure of oxygen in urine is well known, a detailed explanation is omitted. The control unit 31 may calculate and display any indicator defined by the user. The control unit 31 may calculate and display multiple indicators in parallel. The control unit 31 may change the indicator to be calculated depending on the item for which measurement data has been obtained.

[0144] Figure 25 is a flowchart illustrating the processing flow of the program in Embodiment 3. The program in Figure 25 is executed in place of the program described using Figure 6.

[0145] The control unit 31 displays a graph on the touch panel 35 (step S521). The control unit 31 calculates an index based on a predetermined definition (step S581). If the number of data points recorded in the measurement value DB 51 is insufficient and the index cannot be calculated, the control unit 31 waits until the required number of data points are recorded in the measurement value DB 51.

[0146] The control unit 31 creates a new record in the indicator DB and records the calculated indicator and the calculation date and time (step S582). The subsequent processing is the same as the processing flow explained using Figure 6, so the explanation is omitted.

[0147] In step S522, the control unit 31 may read data from the indicator DB and display or update a graph related to the indicator.

[0148] Figure 26 is an explanatory diagram showing an example of the display screen of Embodiment 3. In Figure 26, the renal indicators column 715 and the estimated renal tissue oxygen partial pressure column 719 are added to the modified screen of Embodiment 1 described using Figure 14.

[0149] The estimated kidney tissue oxygen partial pressure column 719 displays the estimated kidney tissue oxygen partial pressure mentioned above. The kidney indicator column displays indicators related to the state of the kidneys, determined based on the parameters measured using each sensor 38. After the control unit 31 calculates the indicators based on a predetermined calculation formula, it displays the results, ranked as "A+", "A", "A-", "B+", "B", "B-", etc., in the kidney indicator column 715. The downward arrow at the far right of the kidney indicator column 715 indicates that the indicator is showing a downward trend.

[0150] As shown in the renal indicator column 715, by displaying ranked indicators, we can provide a measurement system 10 that allows users to intuitively check the overall assessment results using multiple parameters.

[0151] Figure 27 is an explanatory diagram showing an example of the display screen of Embodiment 3. In Figure 27, a renal indicator section 715 is added to the modified screen of Embodiment 1 described using Figure 13. The graph section 711 in Figure 27 includes a candlestick chart, as described using Figure 15, and a bar graph representing an arbitrary indicator. When using candlestick charts and line graphs, the user can easily grasp the trend of the indicator. When using bar graphs, the user can easily grasp the total amount per unit time. It is desirable that the user can appropriately change the format of the graph section 711 depending on the purpose of using the measurement system 10.

[0152] Figure 28 is an explanatory diagram showing an example of the display screen of Embodiment 3. In Figure 28, the oxygen partial pressure column 712, the urine flow rate column 714, and the renal indicator column 715 are displayed in a so-called tile format at the top of the screen. A kidney icon 718 is displayed in the center of the screen.

[0153] The control unit 31 determines the display format of the kidney icon 718 based on an arbitrary indicator or parameter, such as a renal index. For example, the control unit 31 displays the kidney icon 718 in blue if the renal index is rank A, in black if the renal index is rank B, and in red if the renal index is rank C.

[0154] The indicator calculated by the control unit 31 may be the rate of urine flow per unit body weight or the mass rate of oxygen flowing through the indwelling bladder catheter 15 per unit body weight. The indicator calculated by the control unit 31 may be the rate of urine flow per unit body surface area or the mass rate of oxygen flowing through the indwelling bladder catheter 15 per unit body surface area. The patient's body surface area is calculated, for example, based on the patient's height and weight. The control unit 31 implements the function of a rate calculation unit that calculates these rates.

[0155] According to this embodiment, a measurement system 10 can be provided that displays various indicators to support the user's decision-making.

[0156] [Embodiment 4] This embodiment relates to a measurement system 10 that works in conjunction with various devices. Parts common to Embodiment 1 will not be described.

[0157] Figure 29 is an explanatory diagram showing an example of the display screen of Embodiment 4. Figure 29 is an example of the screen displayed by the control unit 31 when the user instructs the display of the device selection screen. A list of devices that can be connected to the measuring device 30 via HIS, etc., is displayed. A device selection button 727 is displayed to the left of the name of each device. The user can select the device to connect via the device selection button 727. In Figure 29, all displayed devices are selected.

[0158] Figure 30 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 30, a renal indicator column 715 is added to the screen of the modified embodiment 1 described using Figure 14. The renal indicator column 715 in Figure 30 displays the renal oxygen supply-excretion ratio.

[0159] The renal oxygen supply-excretion ratio is calculated using the following formula. Renal oxygen supply-excretion ratio = Urine oxygen mass rate / Arterial blood oxygen content × Cardiac output

[0160] The urinary oxygen mass rate can be calculated using a known calculation method based on the urinary oxygen concentration and the urine flow rate. As mentioned above, the urinary oxygen concentration can be calculated using a known calculation method based on the urinary oxygen partial pressure. The control unit 31 acquires arterial blood oxygen content and cardiac output from the pulmonary artery catheter 194 or a blood gas monitoring device (not shown in the illustration). In other words, the control unit 31 functions as a pulmonary artery catheter data acquisition unit that acquires data measured using the pulmonary artery catheter 194.

[0161] The renal oxygen supply-excretion ratio is dimensionless. By using milligrams / min for the urinary oxygen mass rate, milligrams / deciliter for the arterial blood oxygen content, and liters / min for cardiac output, a measurement system 10 can be provided that makes it easy for the user to understand the fluctuations in the renal oxygen supply-excretion ratio.

[0162] The renal oxygen supply-excretion ratio in patients undergoing extracorporeal circulation is calculated using the following formula. Renal oxygen supply-excretion ratio = Urine oxygen mass rate / Arterial blood oxygen content × Pump flow rate

[0163] The control unit 31 acquires the pump flow rate from the extracorporeal circulation device 193. By using liters / minute as the unit for the pump flow rate, similar to the unit for cardiac output described above, a measurement system 10 can be provided that makes it easy for the user to understand the fluctuations in the renal oxygen supply-excretion ratio.

[0164] The renal oxygen supply-excretion ratio is an example of an indicator used to estimate the oxygen supply and demand state of the kidneys. By calculating the renal oxygen supply-excretion ratio, the control unit 31 realizes the function of an oxygen supply and demand estimation unit that estimates the oxygen supply and demand state of the kidneys.

[0165] The control unit 31 may determine the oxygen supply and demand status of the kidney based on the data measured using the pulmonary artery catheter 194 and the data measured using the sensor 38. The control unit 31 implements the function of an oxygen supply and demand monitoring unit that grasps the oxygen supply and demand status of the kidney.

[0166] The control unit 31 may display the renal oxygen excretion rate in the renal indicator column 715. The renal oxygen excretion rate indicates the amount of oxygen dissolved in the urine and excreted by the kidneys, and is calculated by the following formula. Renal oxygen excretion rate = urinary oxygen concentration × urine flow rate

[0167] By using milligrams / milliliter as the unit for urinary oxygen concentration and milliliters / minute as the unit for urine flow rate, a measurement system 10 can be provided that makes it easy for users to understand the fluctuations in renal oxygen excretion rate.

[0168] The control unit 31 may display the central renal oxygen partial pressure ratio in the renal indicator column 715. The renal oxygen partial pressure ratio is calculated by the following formula. Central renal oxygen partial pressure ratio = urinary oxygen concentration / arterial blood oxygen content

[0169] By using milligrams / liter for urinary oxygen concentration and milligrams / deciliter for arterial blood oxygen content, a measurement system 10 can be provided that makes it easy for users to understand the fluctuations in the central renal oxygen partial pressure ratio.

[0170] The control unit 31 may display the renal oxygen supply-excretion ratio during extracorporeal circulation in the renal indicator column 715. The renal oxygen supply-excretion ratio during extracorporeal circulation indicates the ratio of the amount of oxygen delivered from the extracorporeal circulation device 193 during extracorporeal circulation to the aforementioned renal oxygen excretion rate. The amount of oxygen delivered from the extracorporeal circulation device 193 is obtained from the extracorporeal circulation device 193.

[0171] Figure 31 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 31, the screen of the modified example of Embodiment 1 described using Figure 13 has a mode field 736 and an other device field 737 added to it.

[0172] The mode column 736 displays the name of the mode, which is determined for each screen layout or each setting of the measuring device 30. In Figure 31, it is indicated that this is the "Surgical Mode," which is suitable for use during surgery.

[0173] The "Other Equipment" section 737 displays various data obtained from devices such as the vital signs measuring device 191, along with their abbreviations. The data displayed in the "Other Equipment" section 737 includes, for example, the amount of blood stored, the amount of fluid infused, the amount of blood loss, the amount of blood transfused, the perfusion flow rate, or the perfusion pressure obtained from the extracorporeal circulation device 193 during extracorporeal circulation. The control unit 31 implements the function of the extracorporeal circulation data acquisition unit, which acquires this data from the extracorporeal circulation device 193. The extracorporeal circulation data acquisition unit is an example of an external data acquisition unit.

[0174] The data displayed in the "Other Devices" section 737 includes, for example, the partial pressure of oxygen in circulating blood, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess. The control unit 31 implements the function of a circulating blood data acquisition unit that acquires this data from devices such as the vital signs measuring device 191. The circulating blood data acquisition unit is an example of an external data acquisition unit.

[0175] As shown in the example screen in Figure 31, users can avoid the hassle of checking the screens of devices located in various places.

[0176] Figure 32 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 32, the oxygen partial pressure column 712, the temperature column 713, and the urine flow rate column 714 are displayed along with an overview of the progress of the surgery.

[0177] The downward-pointing arrow in the center of the screen shown in Figure 32 indicates the passage of time. The completion of key surgical steps is indicated by the white circles, which represent event indicators 716. To the left of each event indicator 716, an abbreviation or icon indicating the content of the event is displayed.

[0178] The control unit 31 displays the event indicator 716 based on information obtained from a surgical management system or the like that records the progress of the surgery. The control unit 31 may also display the event indicator 716 based on user instructions given for each event that occurs.

[0179] The latest measurement indicator 717, indicated by a black circle, shows the timing of the most recent measurement taken by the measuring device 30. The date and time of the latest measurement are displayed to the left of the latest measurement indicator 717. Users can view data at any given time by sliding the black circle on the time axis to understand the patient's condition.

[0180] Figure 33 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 33, the event indicator 716 is superimposed on the graph section 711 of the screen described using Figure 26. The event indicator 716 indicates the type of event that occurred by shapes such as a black inverted triangle, a white inverted triangle, and a black circle.

[0181] Arrows extending to the right from event indicator 716, indicated by black and white inverted triangles, indicate that the event is ongoing. Event indicator 716, indicated by a black circle, has no arrow extending because it ended quickly. Events include blood transfusions, medication administration, interventions, timing of data extraction, initiation and termination of extracorporeal circulation during surgery, insertion and removal of pulmonary artery catheter 194, and use of ventilator 192. Users can check what kind of event it was by touching event indicator 716. For example, if the event was medication administration, a pop-up will display brief information such as the prescription of the administered medication.

[0182] The measurement system 10, illustrated in Figures 32 and 33, allows the user to view the parameters measured by the measuring device 30 along with the overall flow of the surgery.

[0183] Figure 34 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 34, a lung icon 751, a heart icon 752, and a kidney icon 718 are displayed on the screen described using Figure 28. At the bottom of the screen, there is a notification area 74 indicating a high risk of developing AKI (Acute Kidney Injury) and a notification area 74 indicating a moderate risk of developing ARDS (Acute Respiratory Distress Syndrome).

[0184] The control unit 31 highlights the icons indicating organs closely related to the risk displayed in the notification area 74 by coloring or flashing them.

[0185] The control unit 31 determines the AKI risk and ARDS risk based on indicators calculated using parameters measured by, for example, the sensor 38 and data acquired from other devices, and displays the notification area 74 if the risk is high. The control unit 31 may also display information acquired from other devices in the notification area 74, etc.

[0186] Figure 35 is an explanatory diagram showing an example of the display screen of Embodiment 4. In Figure 35, the heart icon 752 and the kidney icon 718 are displayed on the screen described using Figure 28. The values ​​of SaO2 (Arterial Oxygen Saturation) and SvO2 (mix Venous Oxygen Saturation) are displayed to the left and right of the heart icon 752. The oxygen excretion rate described in Figure 30 and the renal oxygen supply-excretion ratio described in Figure 26 are displayed to the left and right of the kidney icon 718.

[0187] At the bottom of the screen, there is a notification section 74 indicating a high risk of AKI, and another notification section 74 recommending intravenous fluids or a blood transfusion, stating, "Consider the type of intravenous fluid. A blood transfusion may be effective."

[0188] The control unit 31 determines the AKI risk and recommended actions based on indicators calculated using, for example, parameters measured by the sensor 38 and data acquired from other devices, and displays the notification area 74. The control unit 31 may also display information acquired from other devices in the notification area 74, etc.

[0189] The control unit 31 may, for example, acquire diuretic administration data from the drug administration device 196 and determine changes in urine flow rate or changes in oxygen partial pressure in the urine associated with diuretic administration. The control unit 31 may also estimate the state of renal function based on changes in urine flow rate or changes in oxygen partial pressure in the urine. In this case, the control unit 31 implements the functions of a diuretic data acquisition unit that acquires diuretic administration data, and a renal function estimation unit that estimates renal function based on changes in urine flow rate or changes in oxygen partial pressure in the urine associated with diuretic administration. The diuretic data acquisition unit is an example of a drug administration data acquisition unit.

[0190] The control unit 31 may also be equipped with functions to support various tests, such as tests related to diuretic responsiveness or tests related to fluid responsiveness. A test related to diuretic responsiveness will be explained as an example. The user administers a predetermined amount of a diuretic, such as furosemide, to the patient.

[0191] The control unit 31 obtains the time the diuretic was administered from the drug administration device 196. The control unit 31 displays the urine flow rate and urinary oxygen partial pressure within a predetermined time period from the time the diuretic was administered on the display unit 351 in a manner that allows comparison with data from before the diuretic was administered. The control unit 31 may also display the urinary oxygen partial pressure on the display unit 351 along with the urine flow rate.

[0192] The user can check the change in urine flow rate due to diuretics, i.e., the patient's diuretic responsiveness. For example, if the urine volume after administration of a diuretic is below the standard volume, the user may suspect that renal dysfunction is progressing. The control unit 31 may display the standard volume along with the patient's urine flow rate on the display unit 351 to support the user's judgment. The user can check the load that the diuretic has placed on the renal parenchyma based on the change in urinary oxygen partial pressure. Thus, a measuring device 30 that supports the examination of diuretic responsiveness can be provided.

[0193] The control unit 31 may display a diuretic effect evaluation index calculated by the following formula. Diuretic efficacy indicator = Urine flow rate × Elapsed time / Diuretic dosage

[0194] In the above formula, the elapsed time indicates the time elapsed after diuretic administration. By using milliliters / minute as the unit for urine flow rate, minutes as the unit for elapsed time, and milligrams as the unit for diuretic dose, a measurement system 10 can be provided that makes it easy for the user to understand the changes in the renal oxygen supply-excretion ratio.

[0195] The control unit 31 may display the second diuretic effect evaluation index calculated by the following formula. Second diuretic efficacy evaluation index = urinary oxygen mass rate / diuretic efficacy evaluation index

[0196] The second diuretic efficacy indicator is dimensionless. By using milligrams / min as the unit for the urinary oxygen mass rate and milliliters / milligram as the unit for the diuretic efficacy indicator, a measurement system 10 can be provided that makes it easy for the user to understand the fluctuations in the renal oxygen supply-excretion ratio.

[0197] The control unit 31 may display the sodium excretion rate calculated by the following formula. Sodium excretion rate = Urinary sodium concentration × Urine flow rate

[0198] By using milligrams / milliliter as the unit for urinary sodium concentration and milliliters / minute as the unit for urine flow rate, a measurement system 10 can be provided that makes it easy for users to understand fluctuations in the sodium excretion rate.

[0199] The control unit 31 may determine the patient's fluid balance based on parameters measured using the sensor 38 and data acquired from other devices. The control unit 31 implements the functions of the fluid balance determination unit.

[0200] The control unit 31 may output data predicting the risk of renal function decline within an arbitrary period, such as within 7 days post-surgery or within 90 days post-surgery, based on parameters measured using the sensor 38 and data acquired from other devices. In this case, the control unit 31 implements the function of a renal function decline risk prediction unit.

[0201] The control unit 31 may output a predicted value regarding the future level of increase in serum creatinine levels based on parameters measured using the sensor 38 and data acquired from other devices. In this case, the control unit 31 implements the function of a serum creatinine prediction unit.

[0202] The control unit 31 may display treatment guidelines for the patient based on parameters measured using the sensor 38, data acquired from other devices, and disease-specific guidelines.

[0203] The control unit 31 may calculate and display a recommended value for the inhaled oxygen concentration based on the parameters measured using the sensor 38 and the inhaled oxygen concentration data obtained from the ventilator 192. In this case, the control unit 31 implements the functions of the inhaled oxygen concentration data acquisition unit.

[0204] [Embodiment 5] This embodiment relates to a fluorescence measuring instrument 40 that receives fluorescence emitted from two types of phosphors 39 via a single optical fiber 41. Parts common to Embodiment 3 will not be described.

[0205] Figure 36 is an explanatory diagram illustrating the configuration of the fluorescence meter 40 of Embodiment 5. The fluorescence meter 40 of this embodiment comprises one light source 42, a beam splitter 43, a second beam splitter 44, and two fluorescence detection units 46, a first fluorescence detection unit 461 and a second fluorescence detection unit 462. The first fluorescence detection unit 461 and the second fluorescence detection unit 462 are connected to the same calculation unit 47.

[0206] The light source 42 is connected to the beam splitter 43 via the light guide path 45. The beam splitter 43 is connected to the first connector 371 via the light guide path 45. The second beam splitter 44 is connected to the beam splitter 43 via the light guide path 45.

[0207] The first fluorescence detection unit 461 and the second fluorescence detection unit 462 are each connected to the second beam splitter 44 via a light guide path 45. The second beam splitter 44 is a dichroic beam splitter that optically separates the incident light based on its wavelength.

[0208] Two fluorescence sensors 381 are connected to the fluorescence measuring instrument 40. One fluorescence sensor 381 has a first phosphor 391. The other fluorescence sensor 381 has a second phosphor 392. The first phosphor 391 and the second phosphor 392 react to different components in the urine, emitting fluorescence at different wavelengths.

[0209] The two fluorescent sensors 381 may be placed close together or far apart. One fluorescent sensor 381 may contain a first phosphor 391 and a second phosphor 392.

[0210] The light source 42 emits excitation light that excites both the first phosphor 391 and the second phosphor 392. The excitation light emitted from the light source 42 irradiates the first phosphor 391 and the second phosphor 392 via the light guide path 45, beam splitter 43, and optical fiber 41. The first phosphor 391 and the second phosphor 392 each emit fluorescence when they come into contact with urine.

[0211] Fluorescence is incident on the beam splitter 43 via the optical fiber 41 and the light guide path 45. The beam splitter 43 directs the fluorescence into the light guide path 45 connected to the second beam splitter 44. The second beam splitter 44 separates the fluorescence from the fluorescence emitted by the first phosphor 391 and the remaining light. The fluorescence emitted by the first phosphor 391 is incident on the first fluorescence detection unit 461, and the remaining light is incident on the second fluorescence detection unit 462. The second beam splitter 44 functions as a spectrometer that spectrally analyzes the fluorescence acquired from multiple fluorescence sensors 381.

[0212] The first fluorescence detection unit 461 and the second fluorescence detection unit 462 convert the incident light into electrical signals. The calculation unit 47 analyzes the electrical signals and calculates the measurement items corresponding to each fluorescence sensor 381. The calculation unit 47 also functions as an analysis unit, analyzing each spectrally separated fluorescence based on a predetermined algorithm.

[0213] [Embodiment 6] This embodiment relates to a configuration in which the measuring device 30 of this embodiment is realized by operating a program 97 recorded on a portable recording medium 96. Figure 37 is an explanatory diagram illustrating the configuration of the measuring device 30 of Embodiment 6.

[0214] The measuring device 30 in this embodiment includes a reading unit 37. The program 97 is recorded on a portable recording medium 96. The control unit 31 reads the program 97 via the reading unit 37 and saves it to the auxiliary storage device 33. The control unit 31 may also read the program 97 stored in a semiconductor memory 98, such as a flash memory, implemented within the measuring device 30. Furthermore, the control unit 31 may download the program 97 from another server computer (not shown) connected via a communication unit 34 and a network (not shown) and save it to the auxiliary storage device 33.

[0215] Program 97 is installed as the control program for the measuring device 30, loaded into the main memory 32, and executed.

[0216] [Embodiment 7] Figure 38 is a functional block diagram of the measurement system 10 of Embodiment 7. The measurement system 10 comprises a sensor 38 and a measuring device 30. The sensor 38 is positioned to be in contact with the urine being collected by the catheter 15.

[0217] The measuring device 30 comprises a sensor data acquisition unit 81, a measuring unit 82, a display unit 83, and a reception unit 84. The sensor data acquisition unit 81 acquires sensor data from the sensor 38. The measuring unit 82 sequentially measures parameters related to urine based on the sensor data acquired by the sensor data acquisition unit 81. The display unit 83 displays the parameters in a graph using a time axis. The reception unit 84 receives instructions to change the time axis.

[0218] The technical features (constituent elements) described in each embodiment are combinable with each other, and by combining them, new technical features can be formed. The embodiments disclosed herein should be considered in all respects to be illustrative and not restrictive. The scope of the invention is indicated by the claims, not in the sense described above, and all modifications within the meaning and scope equivalent to the claims are intended to be included. [Explanation of Symbols]

[0219] 10 Measurement Systems 15. Indwelling urinary catheter (catheter) 151 Side hole 152 Balloons 153 Shaft 154 Urination funnel 17 Urine collection bag 171 Bags 172 Urine collection tube 191 Vital signs measuring device 192 Respirator 193 Extracorporeal circulation device 194 Pulmonary artery catheter 195 Left ventricular catheter 196 Drug administration device 197 Atmospheric barometer 30 Measuring device 31 Control Unit 32 Main storage 33 Auxiliary storage device 34 Communications Department 35 Touch Panel 351 Display section 352 Input section 368 Temperature measuring device 369 Flow meter 37 Reading Unit 371 First connector 372 Second connector 373 Third connector 378 Temperature sensor connector 379 Flow Sensor Connector 38 sensors 381 Fluorescence Sensor 388 Temperature Sensor 389 Flow Sensor 39. Phosphors 391 First Phosphor 392 Second Phosphor 40 Fluorescence Measuring Instruments 41 Optical Fiber 411 Fiber Optic Connector 412 Irradiation fiber 413 Light-receiving fiber 42 Light source 43 Beam Splitter 44. Second beam splitter 45 Light guide 46 Fluorescence detection unit 461 First fluorescence detection unit 462 Second Fluorescence Detection Unit 47 Calculation Section 471 First Calculation Unit 472 Second Calculation Unit 51 Measurement Value Database 711 Graph section 712 Oxygen Partial Pressure Column 713 Temperature field 714 Urine flow field 715 Renal index column 716 Event Indicators 717 Latest measurement indicators 718 Kidney icon 719 Estimated kidney tissue oxygen partial pressure column 721 Menu display button 722 Time axis change button (reception area) 724 Menu Selection Button 725 ID reading button 726 Patient Information Retrieval Button 727 Select connected device button 731 Patient Information Section 732 Date and time column 733 Attending physician column 734 Entry time column 735 Measurement Information Section 736 Mode section 737 Other equipment column 74 Notification column 751 Lung icon 752 Heart icon 81 Sensor data acquisition unit 82 Measuring part 83 Display section 84 Reception Department 96 Portable recording media 97 Programs 98 Semiconductor memory

Claims

1. A measuring unit sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with the urine being collected via a catheter, A display unit that displays the aforementioned parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, It includes an external data acquisition unit that acquires data measured using a ventilator, an extracorporeal circulation device, a pulmonary artery catheter, or a left ventricular catheter, The display unit displays the data acquired by the external data acquisition unit, along with a graph displaying the parameters. When the receiving unit receives a change instruction regarding the time axis, the external data acquisition unit acquires data corresponding to the range of the time axis that has been changed based on the change instruction. Measuring device.

2. A patient information acquisition unit that acquires at least one of the following: age, sex, weight, serum creatinine level, or urea nitrogen level, A serum creatinine prediction unit predicts the future level of increase in serum creatinine levels based on the data acquired by the patient information acquisition unit and the data acquired by the external data acquisition unit. The measuring device according to claim 1, comprising:

3. A measuring unit sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with the urine being collected via a catheter, A display unit that displays the aforementioned parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, An extracorporeal circulation data acquisition unit that acquires at least one of the following during extracorporeal circulation: blood storage volume, fluid infusion volume, blood loss volume, blood transfusion volume, perfusion flow rate, or perfusion pressure. A circulating blood data acquisition unit that acquires at least one of the following from circulating blood: partial pressure of oxygen, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess. The system includes an oxygen supply and demand estimation unit that estimates the oxygen supply and demand state of the kidney based on the data acquired by the extracorporeal circulation data acquisition unit, the data acquired by the circulating blood data acquisition unit, and the parameters. When the reception unit receives a change instruction regarding the time axis, the extracorporeal circulation data acquisition unit and the circulating blood data acquisition unit acquire data corresponding to the changed range of the time axis based on the change instruction. Measuring device.

4. A measuring unit sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with the urine being collected via a catheter, A display unit that displays the aforementioned parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, A pulmonary artery catheter data acquisition unit that acquires at least one of arterial blood oxygen content, cardiac output, or arterial blood oxygen saturation measured using a pulmonary artery catheter, The system includes an oxygen supply and demand assessment unit that assesses the oxygen supply and demand status of the kidney based on the data acquired by the pulmonary artery catheter data acquisition unit and the parameters, When the reception unit receives a change instruction regarding the time axis, the pulmonary artery catheter data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measuring device.

5. A measuring unit sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with the urine being collected via a catheter, A display unit that displays the aforementioned parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, A drug administration data acquisition unit that acquires data from a drug administration device, The system includes a fluid balance determination unit that determines the fluid balance based on the data acquired by the drug administration data acquisition unit and the parameters, When the reception unit receives a change instruction regarding the time axis, the drug administration data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measuring device.

6. The aforementioned parameters include urine flow rate or partial pressure of oxygen in urine. The drug administration data acquisition unit includes a diuretic data acquisition unit that acquires diuretic administration data. The system includes a renal function estimation unit that estimates renal function based on changes in urine flow rate or changes in the partial pressure of oxygen in the urine associated with diuretic administration, which are determined based on the diuretic administration data acquired by the diuretic data acquisition unit. The measuring device according to claim 5.

7. A measuring unit sequentially measures parameters related to urine based on information obtained from sensors positioned to come into contact with the urine being collected via a catheter, A display unit that displays the aforementioned parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, It includes an inhaled oxygen concentration data acquisition unit that acquires inhaled oxygen concentration data, Based on the inhaled oxygen concentration data acquired by the inhaled oxygen concentration data acquisition unit and the parameters, a recommended value for the inhaled oxygen concentration is calculated. When the reception unit receives a change instruction regarding the time axis, the inhaled oxygen concentration data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measuring device.

8. The aforementioned parameters include at least one of the following: urine flow rate, partial pressure of oxygen in urine, partial pressure of carbon dioxide, temperature, potassium concentration in urine, sodium concentration, hydrogen ion concentration index, or creatinine value. A measuring device according to any one of claims 1 to 7.

9. The aforementioned parameters include the partial pressure of oxygen in urine, The measurement unit includes a correction unit that corrects the partial pressure of oxygen in the urine measured by the measurement unit using at least one of atmospheric pressure, bladder pressure, temperature, or chloride concentration in the urine. A measuring device according to any one of claims 1 to 8.

10. The measurement unit includes an optical flow sensor, an ultrasonic flow sensor, a thermal flow sensor, or a flow rate measuring unit that measures urine flow rate based on changes in the weight of the catheterized urine. A measuring device according to any one of claims 1 to 9.

11. The system includes a second measuring unit that measures at least one of the following based on information obtained from a sensor positioned in a location that does not come into contact with the urine being drawn in by the catheter: urine specific gravity, intrabladder pressure, blood flow velocity around the urethra, or urine flow rate. A measuring device according to any one of claims 1 to 10.

12. The system includes a rate calculation unit that calculates the rate of urine flow per unit body weight, the rate of urine flow per unit body surface area, the mass rate of oxygen flowing through the catheter per unit body weight, or the mass rate of oxygen flowing through the catheter per unit body surface area. A measuring device according to any one of claims 1 to 11.

13. The sensor includes a first sensor located inside the bladder and a second sensor located outside the body. A measuring device according to any one of claims 1 to 12.

14. The sensor includes two or more oxygen sensors and two or more temperature sensors. A measuring device according to any one of claims 1 to 13.

15. The sensor includes a fluorescent sensor having a phosphor that emits fluorescence corresponding to a predetermined measurement item. The aforementioned fluorescence sensors are multiple in number. Each of the aforementioned fluorescent sensors is equipped with a single fluorescence detection unit that detects the fluorescence emitted from the phosphor. A measuring device according to any one of claims 1 to 14.

16. The sensor includes a fluorescent sensor having a phosphor that emits fluorescence corresponding to a predetermined measurement item when it comes into contact with urine. The aforementioned fluorescence sensors are multiple in number. A spectrometer that spectrally analyzes the fluorescence emitted by each of the multiple fluorescent sensors, An analysis unit analyzes each fluorescence spectrally separated by the aforementioned spectrometer based on a predetermined algorithm. A measuring device according to any one of claims 1 to 14, comprising:

17. A patient information acquisition unit that acquires at least one of the following: age, sex, weight, serum creatinine level, or urea nitrogen level, Based on the data acquired by the patient information acquisition unit and the parameters, a renal function decline risk prediction unit predicts the risk of renal function decline within 7 days or 90 days post-surgery. A measuring device according to any one of claims 1 to 16, comprising:

18. The display unit displays a graph showing the parameters, along with treatment guidelines based on those parameters. A measuring device according to any one of claims 1 to 17.

19. A sensor eigenvalue acquisition unit that acquires sensor eigenvalues ​​that are uniquely defined for the aforementioned sensor, The system includes a calibration unit that performs calibration of the sensor based on the sensor's eigenvalues. A measuring device according to any one of claims 1 to 18.

20. In a measurement system comprising a sensor and a measuring device, The sensor is positioned to be in contact with the urine being drawn in by the catheter. The measuring device is, A sensor data acquisition unit that acquires sensor data from the aforementioned sensor, A measurement unit sequentially measures parameters related to urine based on the sensor data acquired by the aforementioned sensor data acquisition unit, A display unit that displays the parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, It includes an external data acquisition unit that acquires data measured using a ventilator, an extracorporeal circulation device, a pulmonary artery catheter, or a left ventricular catheter, The display unit displays the data acquired by the external data acquisition unit, along with a graph displaying the parameters. When the receiving unit receives a change instruction regarding the time axis, the external data acquisition unit acquires data corresponding to the range of the time axis that has been changed based on the change instruction. Measurement system.

21. In a measurement system comprising a sensor and a measuring device, The sensor is positioned to be in contact with the urine being drawn in by the catheter. The measuring device is, A sensor data acquisition unit that acquires sensor data from the aforementioned sensor, A measurement unit sequentially measures parameters related to urine based on the sensor data acquired by the aforementioned sensor data acquisition unit, A display unit that displays the parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, An extracorporeal circulation data acquisition unit that acquires at least one of the following during extracorporeal circulation: blood storage volume, fluid infusion volume, blood loss volume, blood transfusion volume, perfusion flow rate, or perfusion pressure. A circulating blood data acquisition unit that acquires at least one of the following from circulating blood: partial pressure of oxygen, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess. The system includes an oxygen supply and demand estimation unit that estimates the oxygen supply and demand state of the kidney based on the data acquired by the extracorporeal circulation data acquisition unit, the data acquired by the circulating blood data acquisition unit, and the parameters. When the reception unit receives a change instruction regarding the time axis, the extracorporeal circulation data acquisition unit and the circulating blood data acquisition unit acquire data corresponding to the changed range of the time axis based on the change instruction. Measurement system.

22. In a measurement system comprising a sensor and a measuring device, The sensor is positioned to be in contact with the urine being drawn in by the catheter. The measuring device is, A sensor data acquisition unit that acquires sensor data from the aforementioned sensor, A measurement unit sequentially measures parameters related to urine based on the sensor data acquired by the aforementioned sensor data acquisition unit, A display unit that displays the parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, A pulmonary artery catheter data acquisition unit that acquires at least one of arterial blood oxygen content, cardiac output, or arterial blood oxygen saturation measured using a pulmonary artery catheter, The system includes an oxygen supply and demand assessment unit that assesses the oxygen supply and demand status of the kidney based on the data acquired by the pulmonary artery catheter data acquisition unit and the parameters, When the reception unit receives a change instruction regarding the time axis, the pulmonary artery catheter data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measurement system.

23. In a measurement system comprising a sensor and a measuring device, The sensor is positioned to be in contact with the urine being drawn in by the catheter. The measuring device is, A sensor data acquisition unit that acquires sensor data from the aforementioned sensor, A measurement unit sequentially measures parameters related to urine based on the sensor data acquired by the aforementioned sensor data acquisition unit, A display unit that displays the parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, A drug administration data acquisition unit that acquires data from a drug administration device, The system includes a fluid balance determination unit that determines the fluid balance based on the data acquired by the drug administration data acquisition unit and the parameters, When the reception unit receives a change instruction regarding the time axis, the drug administration data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measurement system.

24. In a measurement system comprising a sensor and a measuring device, The sensor is positioned to be in contact with the urine being drawn in by the catheter. The measuring device is, A sensor data acquisition unit that acquires sensor data from the aforementioned sensor, A measurement unit sequentially measures parameters related to urine based on the sensor data acquired by the aforementioned sensor data acquisition unit, A display unit that displays the parameters in a graph using a time axis, A reception unit that receives change instructions regarding the aforementioned time axis, It includes an inhaled oxygen concentration data acquisition unit that acquires inhaled oxygen concentration data, Based on the inhaled oxygen concentration data acquired by the inhaled oxygen concentration data acquisition unit and the parameters, a recommended value for the inhaled oxygen concentration is calculated. When the reception unit receives a change instruction regarding the time axis, the inhaled oxygen concentration data acquisition unit acquires data corresponding to the changed range of the time axis based on the change instruction. Measurement system.

25. Information is obtained from a sensor that can come into contact with the urine being collected via a catheter. Using the acquired information, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Data is obtained using a ventilator, extracorporeal circulation device, pulmonary artery catheter, or left ventricular catheter. Along with a graph displaying the aforementioned parameters, the acquired data measured using the ventilator, the extracorporeal circulation device, the pulmonary artery catheter, or the left ventricular catheter is displayed. When a change instruction regarding the time axis is received, data measured using the ventilator, the extracorporeal circulation device, the pulmonary artery catheter, or the left ventricular catheter corresponding to the range of the time axis changed based on the change instruction is acquired. An information processing method in which a computer performs the processing.

26. Information is obtained from a sensor that can come into contact with the urine being collected via a catheter. Using the acquired information, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. During extracorporeal circulation, obtain at least one of the following: blood volume stored, fluid volume infused, blood loss, blood transfusion volume, perfusion flow rate, or perfusion pressure. Obtain at least one of the following from the circulating blood: partial pressure of oxygen, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess. Based on the data acquired during extracorporeal circulation, and at least one of the following parameters: partial pressure of oxygen in the circulating blood, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess, the oxygen supply and demand status of the kidney is estimated. When a change instruction regarding the aforementioned time axis is received, data corresponding to the range of the time axis changed based on the change instruction is acquired. An information processing method in which a computer performs the processing.

27. Information is obtained from a sensor that can come into contact with the urine being collected via a catheter. Using the acquired information, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. At least one of the following is obtained using a pulmonary artery catheter: arterial blood oxygen content, cardiac output, or arterial blood oxygen saturation. Based on the data measured using the pulmonary artery catheter and the parameters, the oxygen supply and demand status of the kidneys is determined. When a change instruction regarding the time axis is received, data measured using the pulmonary artery catheter corresponding to the range of the time axis changed based on the change instruction is acquired. An information processing method in which a computer performs the processing.

28. Information is obtained from a sensor that can come into contact with the urine being collected via a catheter. Using the acquired information, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Data is acquired from the drug administration device. Based on the data obtained from the drug administration device and the parameters, the fluid balance is determined. When a change instruction regarding the time axis is received, data corresponding to the changed range of the time axis based on the change instruction is obtained from the drug dispensing device. An information processing method in which a computer performs the processing.

29. Information is obtained from a sensor that can come into contact with the urine being collected via a catheter. Using the acquired information, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Obtain inhaled oxygen concentration data, Based on the acquired inhaled oxygen concentration data and the aforementioned parameters, a recommended value for the inhaled oxygen concentration is calculated. When a change instruction regarding the time axis is received, the inhaled oxygen concentration data corresponding to the range of the time axis changed based on the change instruction is acquired. An information processing method in which a computer performs the processing.

30. Using information acquired from the sensor, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Data is obtained using a ventilator, extracorporeal circulation device, pulmonary artery catheter, or left ventricular catheter. Along with a graph displaying the aforementioned parameters, the acquired data measured using the ventilator, the extracorporeal circulation device, the pulmonary artery catheter, or the left ventricular catheter is displayed. When a change instruction regarding the time axis is received, data measured using the ventilator, the extracorporeal circulation device, the pulmonary artery catheter, or the left ventricular catheter corresponding to the range of the time axis changed based on the change instruction is acquired. A program that instructs a computer to perform a process.

31. Using information acquired from the sensor, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. During extracorporeal circulation, obtain at least one of the following: blood volume stored, fluid volume infused, blood loss, blood transfusion volume, perfusion flow rate, or perfusion pressure. Obtain at least one of the following from the circulating blood: partial pressure of oxygen, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess. Based on the data acquired during extracorporeal circulation, and at least one of the following parameters: partial pressure of oxygen in the circulating blood, partial pressure of carbon dioxide, potassium concentration, sodium concentration, hydrogen ion concentration index, oxygen supply, oxygen saturation, hematocrit value, hemoglobin amount, oxygen consumption, plasma bicarbonate ion concentration, or base excess, the oxygen supply and demand status of the kidney is estimated. When a change instruction regarding the aforementioned time axis is received, data corresponding to the range of the time axis changed based on the change instruction is acquired. A program that instructs a computer to perform a process.

32. Using information acquired from the sensor, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. At least one of the following is obtained using a pulmonary artery catheter: arterial blood oxygen content, cardiac output, or arterial blood oxygen saturation. Based on the data measured using the pulmonary artery catheter and the parameters, the oxygen supply and demand status of the kidneys is determined. When a change instruction regarding the time axis is received, data measured using the pulmonary artery catheter corresponding to the range of the time axis changed based on the change instruction is acquired. A program that instructs a computer to perform a process.

33. Using information acquired from the sensor, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Data is acquired from the drug administration device. Based on the data obtained from the drug administration device and the parameters, the fluid balance is determined. When a change instruction regarding the time axis is received, data corresponding to the changed range of the time axis based on the change instruction is obtained from the drug dispensing device. A program that instructs a computer to perform a process.

34. Using information acquired from the sensor, parameters related to urine are measured sequentially. The parameters are displayed in a graph using a time axis. We have received a change instruction regarding the aforementioned time axis. Obtain inhaled oxygen concentration data, Based on the acquired inhaled oxygen concentration data and the aforementioned parameters, a recommended value for the inhaled oxygen concentration is calculated. When a change instruction regarding the time axis is received, the inhaled oxygen concentration data corresponding to the range of the time axis changed based on the change instruction is acquired. A program that instructs a computer to perform a process.

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