Cleaning agent composition for oral appliances

Abstract

The present invention relates to a method for cleaning an intraoral instrument, which can spread the cleanser composition to every corner of the intraoral instrument while exhibiting excellent foaming, and a cleanser composition for an intraoral instrument. The present invention provides a cleaning composition containing a surfactant (a) having the following properties (i) and (ii): forming a foam having A method for cleaning an intraoral appliance, which comprises covering the intraoral appliance with the foam obtained. (i) Foam specific volume is 7 ml / g or more and 20 ml / g or less, (ii) Drainage rate is 1.6 ml / min or more and 6 ml / min or less

Description

[Technical Field]

[0001] The present invention relates to a method for cleaning oral appliances and a cleaning agent composition for oral appliances. [Background technology]

[0002] With the rapid aging of the population in recent years, the number of people who are forced to wear removable oral appliances such as dentures is increasing at an accelerating rate. Such oral appliances, such as dentures and orthodontic appliances, tend to retain stubborn stains such as oil and plaque that accumulate during wear. In particular, at the edges of oral appliances with complex shapes, stains are difficult to remove and remain firmly attached. Furthermore, wearing oral appliances with these stains remaining can lead to bad breath, dental caries, periodontal disease, and other problems. Therefore, keeping oral appliances clean is essential for maintaining good physical health, and meticulous daily cleaning is indispensable.

[0003] Various compositions and cleaning methods have been developed to effectively clean these oral devices. For example, Patent Document 1 discloses a cleaning agent containing lysozyme chloride, which is filled into a container that can be sprayed in a foamy form, and Patent Document 2 discloses a cleaning formulation that is distributed in the form of aerated foam. Attempts have been made to enhance the cleaning effect and shorten the cleaning time in each of these documents. Furthermore, Patent Documents 3 and 4 disclose liquid compositions containing surfactants, and describe that by housing such compositions in a container that dispenses them as foam and applying them as foam at the time of use, a rapid stain removal effect can be achieved. [Prior art documents] [Patent Documents]

[0004] [Patent Document 1] Japanese Patent Publication No. 2006-117600 [Patent Document 2] Japanese Patent Publication No. 2007-254471 [Patent Document 3] Japanese Patent Publication No. 2010-168352 [Patent Document 4] Japanese Patent Publication No. 2011-126868 [Overview of the project] [Problems that the invention aims to solve]

[0005] However, the technology described in the above-mentioned patent document may not be able to ensure sufficient foaming during use, or, due to an overemphasis on foam shape retention, the composition may not reach every corner of oral devices with complex shapes, and there is still room for improvement.

[0006] Therefore, the present invention relates to a method for cleaning oral devices and a cleaning agent composition for oral devices that can produce excellent foaming while ensuring that the cleaning agent composition reaches every corner of the oral device. [Means for solving the problem]

[0007] Therefore, the inventors conducted diligent studies to solve the above problems and have found a method for cleaning oral devices, and a cleaning agent composition for oral devices used therein, which allows the cleaning agent composition to reach every corner of the oral device while ensuring a sufficient amount of foam by forming foam with a specific foam specific volume and drainage rate using a cleaning agent composition and covering the oral device with this foam.

[0008] In other words, the present invention relates to a detergent composition containing a surfactant (a) having the following properties (i) Form a foam having (ii) and A method for cleaning oral devices, which involves covering the oral device with the resulting foam. (i) Foam specific volume is 7 ml / g or more and 20 ml / g or less, (ii) Drainage rate is 1.6 ml / min or more and 6 ml / min or less This provides...

[0009] Furthermore, the present invention relates to a cleaning agent composition containing a surfactant (a) for forming foam and coating an intraoral device with the resulting foam to clean the intraoral device, The bubbles that are formed are (i) and (ii) below: (i) Foam specific volume is 7 ml / g or more and 20 ml / g or less, (ii) Drainage rate is 1.6 ml / min or more and 6 ml / min or less The present invention provides a cleaning agent composition for oral devices having the following properties. [Effects of the Invention]

[0010] According to the present invention, when cleaning an oral appliance, by coating the oral appliance with foam that exhibits appropriate foaming and drainage properties, the composition can be thoroughly distributed to every corner of even oral appliances with complex shapes, resulting in a cleaning effect that is excellent in removing oil stains, plaque, and other dirt. [Modes for carrying out the invention]

[0011] The present invention will be described in detail below. In this specification, "intraoral appliances" refers to dental appliances that are attached to and removed in the oral cavity, such as complete dentures, partial dentures, orthodontic appliances, retainers, or mouthpieces (hereinafter collectively referred to as "dentures, etc."). Specifically, for example, a complete denture is a denture worn on an edentulous jaw and consists of artificial teeth and a denture base. On the other hand, a partial denture is a denture worn on a jaw where some teeth have been lost and consists of artificial teeth, a denture base, and abutment devices such as clasps, rests, and attachments. Orthodontic appliances, retainers, and mouthpieces have similar structures. The material of the denture base is generally a resin such as acrylic resin, and the material of the artificial teeth and abutment devices is, in addition to such resin, a metal such as titanium or ceramic.

[0012] The cleaning method of the intraoral appliance of the present invention is to form bubbles having the following properties (i) and (ii) with a cleaning agent composition containing a surfactant (a), and to coat the intraoral appliance with the obtained bubbles. This is a cleaning method of an intraoral appliance. (i) The foam specific volume is 7 ml / g or more and 20 ml / g or less. (ii) The drainage rate is 1.6 ml / min or more and 6 ml / min or less.

[0013] That is, the cleaning method of the intraoral appliance of the present invention is a method in which first, a cleaning agent composition containing a surfactant (a) (hereinafter also referred to as the cleaning agent composition in the present invention) forms bubbles having specific foam specific volume and drainage rate properties, and then the obtained bubbles are used to coat the intraoral appliance. By forming bubbles having such specific properties and coating the intraoral appliance with these bubbles, excellent foaming is exhibited, and the cleaning agent composition is applied to the intraoral appliance with rich bubbles. On the other hand, by moderately draining the liquid from the bubbles, the cleaning agent composition can reach every corner of the intraoral appliance with a complex shape, and an effective and excellent cleaning effect can be exerted. Therefore, it is possible to simply and effectively remove dirt such as oil stains and dental plaque on the intraoral appliance only by rinsing and washing away the intraoral appliance after applying the composition with water or the like, without particularly applying a physical additional force such as brushing.

[0014] In the cleaning method of the present invention, the bubbles formed with the cleaning agent composition containing the surfactant (a) have the property that (i) the foam specific volume is 7 ml / g or more and 20 ml / g or less. By having such properties when the bubbles are placed on the intraoral appliance, excellent foaming can be exhibited to ensure a sufficient amount of bubbles, and the bubble shape can be stably maintained without being affected by the thinning or deformation of the bubbles that may occur due to the drainage that progresses after placement. On the other hand, by moderately draining the liquid from the bubbles, the cleaning agent composition can reach every corner of the intraoral appliance with a complex shape, and an effective and excellent cleaning effect can be exerted.

[0015] The foam specific volume (i) of the foam formed in this invention ensures excellent foaming and sufficient foam volume. From this viewpoint, the specific volume (i) of the foam formed in the present invention is such that, as described later, an appropriate drainage rate (ii) is ensured. From this point, it is 20 ml / g or less, preferably 19 ml / g or less, more preferably 18 ml / g or less, and even more preferably 17 ml / g or less. The foam specific volume (i) of the foam formed in the present invention is 7 ml / g or more and 20 ml / g or less, preferably The concentration is 8 to 19 ml / g, more preferably 9 to 18 ml / g, and even more preferably 10 to 17 ml / g.

[0016] In this invention, "Foam specific volume (i)" means the foam volume (ml) per gram of foam. Specifically, it is a value calculated by measuring the foam volume when 15g of foam formed by the detergent composition is collected.

[0017] Furthermore, in the cleaning method of the present invention, the foam formed by the detergent composition containing surfactant (a) has the property of having a drainage rate of 1.6 ml / min or more and 6 ml / min or less. Here, "drainage" means the downward flow of the liquid detergent composition that occurs within the foam film of the formed foam due to the influence of gravity. Because the foam formed in the present invention has such properties, when such foam is placed on an intraoral device, sufficient foam volume and a stable foam shape are ensured by the foam specific volume (i) described above. However, because it exhibits an appropriate drainage rate, the cleaning agent composition, which has been liquefied by the drainage, can reach every corner of the oral appliance.

[0018] In the present invention, the drainage rate (ii) of the foam formed is 1.6 ml / min or more, preferably 1.9 ml / min or more, more preferably 2 ml / min or more, and even more preferably 2.1 ml / min or more, from the viewpoint of quickly distributing the cleaning agent composition to every corner of the oral appliance. Furthermore, in the present invention, the drainage rate (ii) of the foam formed is 6 ml / min or less, preferably 5 ml / min or less, more preferably 4 ml / min or less, and even more preferably 3 ml / min or less, from the viewpoint of effectively suppressing the collapse of the formed foam and maintaining a sufficient amount of foam. And, in the present invention, the drainage rate (ii) of the foam formed is 1.6 ml / min or more and 6 ml / min or less, preferably 1.9 to 5 ml / min, more preferably 2 to 4 ml / min, and even more preferably 2.1 to 3 ml / min.

[0019] In this invention, "drainage rate (ii)" means the volume (ml) of drainage liquid discharged from the foam per minute. Specifically, it is the value obtained by putting foam formed by the detergent composition into a 200 ml cylinder and measuring the time from immediately after the addition until the drainage liquid reaches a height of 10 ml.

[0020] In the cleaning method for oral devices of the present invention, the properties of the foam specific volume (i) and drainage rate (ii) are as described above. After forming foam containing the specified properties, the oral appliance is covered with the resulting foam. This ensures that a sufficient amount of foam is applied to the oral appliance while allowing the drainage solution to quickly reach every corner of the appliance, resulting in an excellent cleaning effect.

[0021] The time for covering the oral appliance with foam is preferably 1 minute or more, more preferably 2 minutes or more, and even more preferably 3 minutes or more, from the viewpoint of fully enjoying the excellent cleaning effect. Furthermore, the time for covering the oral appliance with foam depends on the foam specific volume (i) and the drainage rate (ii) From the viewpoint of fully exhibiting the effect of foam having the properties of ), the duration is preferably 30 minutes or less, more preferably 20 minutes or less, and even more preferably 10 minutes or less. The time for covering the oral appliance with foam is preferably 1 minute or more and 30 minutes or less, more preferably 2 to 20 minutes, and even more preferably 3 to 10 minutes.

[0022] The amount of foam covering the oral appliance shall have the properties of the foam specific volume (i) and drainage rate (ii) described above. From the perspective of fully utilizing the effect of the foam and enjoying the excellent cleaning effect, the surface area of ​​the oral appliance should be 1 cm². 2 Preferably, the amount is 0.05 g or more per unit, and more preferably 0. The amount is 0.7g or more, more preferably 0.1g or more, more preferably 3.5g or less, more preferably 3.2g or less, and even more preferably 3g or less.

[0023] In the method for cleaning an oral appliance of the present invention, the specific volume (i) of the foam formed and the drainage rate When covering an oral device with foam having properties of degree (ii), it is preferable to first place the oral device on a foam holder having an opening on its upper surface and comprising a mounting surface and a peripheral wall, and then cover the oral device with foam. A foam holder having an opening on its upper surface and comprising a mounting surface and a peripheral wall can have any shape that can hold both an intraoral instrument and foam. The peripheral wall may have a shape that gradually changes angle as it rises, or a shape that rises at a constant angle. Specifically, for example, it may be cup-shaped, bowl-shaped, or plate-shaped, or an intraoral instrument carrying case may be used as a foam holder as is. Furthermore, as the foam retainer, a part of the container in which the cleaning agent composition is contained or an accessory of the container may serve as the foam retainer. Specifically, a cap portion attached to the container in which the cleaning agent composition is contained for preventing leakage of the content may have a function as a foam retainer. Thus, if a part of the container in which the cleaning agent composition is contained or an accessory of the container serves as the foam retainer, it is convenient for the user to carry, and it is possible to easily increase the frequency of use and expand the usage scenarios.

[0024] The area of the placement surface of the foam retainer is preferably 5 cm 2 or more, more preferably 7 cm 2 or more, preferably 80 cm 2 or less, more preferably 60 cm 2 or less. Also, the height from the placement surface of such a foam retainer is preferably 0.5 cm or more, more preferably 1.5 cm or more, from the viewpoint of being able to well cover the intraoral appliance placed with foam, and preferably 20 cm or less, more preferably 15 cm or less, from the viewpoint of being able to easily perform the operation of covering the intraoral appliance placed with foam. Furthermore, the internal volume of such a foam retainer is preferably 5 cm 3 or more, more preferably 20 cm 3 or more, preferably 700 cm 3 or less and more preferably 500 cm 3 or less. The material of the foam retainer is preferably made of glass, plastic, metal, or clay such as pottery or porcelain from the viewpoint of effectively preventing foam residue during rinsing after cleaning.

[0025] In the cleaning method of the present invention, it is preferable to rinse the cleaning agent composition by covering the oral device with the formed foam and then rinsing the oral device with water. Alternatively, if the oral device is placed on the foam holder beforehand and then covered with foam, rinsing the oral device while it is still on the foam holder, and if necessary, gently shaking the foam holder with the oral device still on it, and repeating this process multiple times, will remove the cleaning agent. The composition may be washed away. Thus, with the cleaning method of the present invention, simply rinsing the oral appliance with water without requiring any additional physical force can thoroughly remove oily stains, plaque, and other substances that have firmly adhered to the oral appliance while washing away the coating foam. This reduces the burden on elderly users and makes it easier to increase the frequency of use. Furthermore, in the cleaning method of the present invention, it is preferable to rinse the oral appliance with water after covering it with the formed foam, without applying any additional physical force with a toothbrush or other cleaning tool. This makes it possible to remove oily stains, plaque, and other dirt from the oral appliance in a simple and effective manner.

[0026] In the cleaning method of the present invention, foam having the above-mentioned foam specific volume (i) and drainage velocity (ii) is From the viewpoint of effective foam formation, it is preferable to fill the cleaning composition containing the above-mentioned surfactant (a) into a container equipped with a foam-forming mechanism and to form foam by spraying or discharging from the container. A container equipped with a foam-forming mechanism is a container that can form foam by spraying or discharging the contents filled in the container from a nozzle or discharge port to the outside of the container via the foam-forming mechanism. Examples of containers equipped with such a foam-forming mechanism include trigger-type spray containers and pump-type dispenser containers.

[0027] A trigger-type spray container comprises a container body for filling with contents, a trigger which is a foam-forming mechanism, and a discharge part such as a sprayer. When the trigger is pulled during use, the contents are sprayed out from the nozzle (discharge port) of the sprayer, and foam is formed. Such a trigger-type spray container may be a direct-pressure type or a pressurized type. A pump-type dispenser container comprises a container body for filling with contents, a tube or nozzle, and a foam-forming mechanism such as a mesh inside these components. When used, pressing the dispenser or a part of the container causes the contents to be dispensed from the outlet and foam to form. In the cleaning method of the present invention, among these containers, the foam specific volume (i) and drainage rate (ii) From the viewpoint of effectively forming foam having the properties described above, it is preferable to use a trigger-type spray container.

[0028] When a trigger-type spray container is used in the cleaning method of the present invention, the above foam specific volume (i) and discharge From the viewpoint of effectively forming bubbles having the properties of liquid velocity (ii), it is desirable to set the spray diameter at a spray distance of 20 cm to preferably 2 cm or more, more preferably 3 cm or more, preferably 10 cm or less, and more preferably 8 cm or less. Furthermore, in a trigger-type spray container, the spray force of the detergent composition, which is the contents, is determined from the viewpoint of effectively forming foam having the properties of foam specific volume (i) and drainage velocity (ii) as described above, by the spray distance 2 It is desirable to set the jet force at 0 cm to preferably 1 g·f or more, more preferably 3 g·f or more, preferably 10 g·f or less, and more preferably 8 g·f or less.

[0029] Furthermore, in a dispenser equipped with a pump-type dispenser container, from the viewpoint of effectively forming foam having the above-mentioned foam specific volume (i) and drainage velocity (ii), per press Preferably, the device is designed to dispense a quantitative amount of the detergent composition, which is the contents, in an amount of 0.2 g or more, more preferably 0.3 g or more, more preferably 10 g or less, and more preferably 5 g or less. Furthermore, if the foam-forming mechanism contained within the dispenser is a mesh, from the viewpoint of effectively forming foam having the above-mentioned foam specific volume (i) and drainage velocity (ii), such mesh The coarseness is preferably 50 to 400 mesh (number of meshes per inch), more preferably 80 to 200 mesh, and the number of meshes is preferably 2 to 3, more preferably 1 to 2.

[0030] Furthermore, in the cleaning method of the present invention, if a foam holder for holding an intraoral device is used in combination, the intraoral device should be placed on the foam holder beforehand, and then the cleaning composition should be sprayed or discharged from a container equipped with a foam-forming mechanism toward the intraoral device. In this case, if the cap attached to the container equipped with a foam-forming mechanism is used as a foam holder, the oral device can be placed on the removed cap, and then the cleaning composition can be sprayed or discharged from the container equipped with the foam-forming mechanism towards the oral device, thus realizing an even simpler method.

[0031] The cleaning agent composition used in the cleaning method of the present invention is a cleaning agent composition for oral appliances containing a surfactant (a). This provides the properties of foam specific volume (i) and drainage rate (ii). The formation of foam having the above properties (hereinafter also referred to as "the above properties") can be achieved. Examples of such component (a) include one or more selected from anionic surfactants (a1), amphoteric surfactants (a2), and nonionic surfactants (a3).

[0032] Specifically, anionic surfactants (a1) include one or more selected from alkyl sulfate esters such as lauryl sulfate, myristyl sulfate, palmityl sulfate, stearyl sulfate, octyl sulfate, and caprylic sulfate; alkyl sulfonates such as alkylbenzene sulfonates, α-olefin sulfonates, and hydroxyalkane sulfonates; acyl amino acid salts such as acyl glutamates and acyl sarcosine salts; N-methyl long-chain acyl taurate salts such as lauryl methyl taurate; fatty acid salts such as oleates and laurates; alkyl phosphates such as alkyl phosphates; fatty acid ester salts of higher fatty acids and isethionic acid; and polyoxyethylene monoalkyl phosphates. In particular, from the viewpoint of enabling the formation of foam having the above-mentioned properties and ensuring excellent cleaning effect, it is preferable that the substance be one or more selected from alkyl sulfate ester salts and acyl amino acid salts.

[0033] Examples of amphoteric surfactants (a2) include one or more selected from alkylamine oxides such as lauryldimethylamine oxide; acetate betaines such as lauryldimethylaminoacetic acid betaine; imidazolinium betaines such as 2-alkyl-N-carboxymethyl-N-hydroxyethyl-N-imidazolium betaine; alkyl sulfobetaines such as lauryl sulfobetaine and lauryl hydroxysulfobetaine; coconut oil fatty acid amide alkyl betaines such as coconut oil fatty acid amidopropyl betaine; and long-chain alkylimidazoline betaine salts such as N-alkyl-1-hydroxyethylimidazoline betaine sodium. In particular, from the viewpoint of enabling the formation of foam having the above properties and ensuring excellent cleaning effect, one or more selected from alkylamine oxide, lauryl hydroxysulfobetaine, coconut oil fatty acid amide alkylbetaine, and alkyl sulfobetaine are preferred, with alkylamine oxide being more preferred.

[0034] Examples of nonionic surfactants (a3) ​​include one or more selected from polyoxyethylene hydrogenated castor oil; sucrose fatty acid esters; sorbitan fatty acid esters; glycerin fatty acid esters such as monostearate glyceride; alkyl glucosides; polyglycerin fatty acid esters such as monostearate decaglyceride and monomyristate decaglyceride; polyoxyethylene alkylphenyl ethers such as polyoxyethylene monoalkyl (or alkenyl) ethers, polyoxyethylene polyoxypropylene copolymers, and polyoxyethylene nonylphenyl ethers; fatty acid alkanolamides such as coconut oil fatty acid diethanolamide; and polyethylene glycol fatty acid esters. In particular, it enables the formation of foam having the above properties and ensures the exhibition of excellent cleaning effect. From this perspective, polyoxyethylene monoalkyl (or alkenyl) ethers or polyoxyethylene polyoxypropylene copolymers are preferred, and polyoxyethylene monoalkyl (or alkenyl) ethers are more preferred.

[0035] These components (a) are preferably one or more selected from anionic surfactants (a1) and amphoteric surfactants (a2), from the viewpoint of enabling the formation of foam having the above properties and ensuring excellent cleaning effect, and it is also preferable to use anionic surfactants (a1) and amphoteric surfactants (a2) in combination, and more preferably one or more selected from alkyl sulfate ester salts, acyl amino acid salts, and alkylamine oxides, and even more preferably one or more selected from alkyl sulfate ester salts and alkylamine oxides.

[0036] The amount of component (a) enables the formation of foam having the above-mentioned properties (i) and provides excellent foaming. From the viewpoint of ensuring sufficient foam volume through the expression of the foam, the content of component (a) in the cleaning agent composition for oral devices of the present invention is preferably 0.05% by mass or more, more preferably 0.15% by mass or more, even more preferably 0.5% by mass or more, and even more preferably 0.7% by mass or more. Furthermore, from the viewpoint of enabling the formation of foam having the above-mentioned properties (ii) and ensuring that the cleaning effect is fully exerted to every corner of the oral device, the content of component (a) in the cleaning agent composition for oral devices of the present invention is preferably 20% by mass or less, more preferably 15% by mass or less, even more preferably 5% by mass or less, and even more preferably 3% by mass or less. And the content of component (a) in the cleaning agent composition for oral devices of the present invention is preferably 0.05 to 20% by mass, more preferably 0.15 to 15% by mass, even more preferably 0.5 to 5% by mass, and even more preferably 0.7 to 3% by mass.

[0037] The cleaning agent composition for oral devices of the present invention may further contain a hydroxyl group-containing compound (b) having a ClogP value of -3 or more and 1.4 or less, and a mass-average molecular weight of 35 or more and 800 or less. By including such component (b), the formation of foam having the above properties can be effectively promoted together with component (a).

[0038] Here, the "logP value" is the logarithm of the 1-octanol / water partition coefficient of a compound. It represents the ratio of the equilibrium concentrations of the solute in each solvent at the partition equilibrium when the compound is dissolved as a solute in a two-phase solvent system of 1-octanol and water, and is generally expressed in the form of the logarithm "logP" with respect to base 10. In other words, the logP value is an indicator of lipophilicity (hydrophobicity); the higher the value, the more hydrophobic the compound, and the lower the value, the more hydrophilic it is. LogP values ​​can be obtained from sources such as Daylight Chemical Information Systems, Inc. (Daylight CIS). While logP values ​​listed in available databases can be used as measured values, they can also be calculated using programs such as "CLOGP" (Daylight CIS) or EPI Suite (registered trademark, version 4.11). In the program "CLOGP", calculations are performed using the fragment approach of Hansch, Leo. The calculated logP (ClogP) value is output along with any measured logP values, if available. The fragment approach described above is based on the chemical structure of the compound and takes into account the number of atoms and the type of chemical bonds (A. Leo, Comprehensive Medicinal Chemistry, Vol.4, C.Hansch, PGSammens, JBTaylor and CARamsden.Eds., P.295, Pergamon Press, 1990). This ClogP value is currently the most common and reliable estimate, and in this invention, "ClogP value" refers to this value.

[0039] The ClogP value of component (b) is -3 or higher, preferably -2.8 or higher, more preferably -2.6 or higher, even more preferably -2.5 or higher, and 1.4 or lower. It is preferably 1.37 or less, more preferably 1.35 or less, and even more preferably 1.3 or less.

[0040] Furthermore, the mass-average molecular weight of component (b) is 35 or more, preferably 37 or more, more preferably 40 or more, even more preferably 43 or more, and 800 or less, preferably 700 or less, even more preferably 600 or less, and even more preferably 500 or less. In this invention, "mass-average molecular weight" (Mw) refers to the value obtained by gel permeation chromatography (using chloroform solvent, a calibration curve defined with linear polystyrene as the standard, and a refractive index detector).

[0041] Specifically, such component (b) may include one or more selected from ethanol, glycerin, propylene glycol, butylene glycol, dipropylene glycol, ethylene glycol, diethylene glycol monobutyl ether, benzyl alcohol, and phenoxyethanol. In particular, from the viewpoint of forming foam having the above properties well, one or more selected from ethanol, propylene glycol, butylene glycol, dipropylene glycol, ethylene glycol, diethylene glycol monobutyl ether, benzyl alcohol, and phenoxyethanol is preferred, one or more selected from diethylene glycol monobutyl ether, benzyl alcohol, and phenoxyethanol is more preferred, and phenoxyethanol is even more preferred.

[0042] From the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibiting of an excellent cleaning effect, the content of component (b) in the cleaning agent composition for oral devices of the present invention is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, even more preferably 0.5% by mass or more, and even more preferably 0.6% by mass or more. Furthermore, from the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibiting of an excellent cleaning effect, the content of component (b) in the cleaning agent composition for oral devices of the present invention is preferably 30% by mass or less, more preferably 15% by mass or less, even more preferably 9% by mass or less, and even more preferably 7% by mass or less. And, from the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibiting of an excellent cleaning effect, the content of component (b) in the cleaning agent composition for oral devices of the present invention is preferably 0.1% by mass or more and 30% by mass or less, more preferably 0.3 to 15% by mass, even more preferably 0.5 to 9% by mass, and even more preferably 0.6 to 7% by mass.

[0043] In the cleaning agent composition for oral appliances of the present invention, the mass ratio ((b) / (a)) of the content of component (b) to the content of component (a) is preferably 0.01 or more, more preferably 0.05 or more, even more preferably 0.1 or more, preferably 30 or less, more preferably 15 or less, even more preferably 8 or less, and even more preferably 4 or less, from the viewpoint of enabling the formation of foam having the above properties and exhibiting an excellent cleaning effect.

[0044] The cleaning agent composition for oral devices of the present invention preferably further contains an aromatic compound (c) having a ClogP value of 1.5 or more and 4.0 or less, and a mass-average molecular weight of 90 or more and 500 or less. By including such component (c), in combination with component (b), the formation of foam having the above properties can be further facilitated.

[0045] The ClogP value of component (c) is 1.5 or higher, preferably 1.6 or higher, more preferably 1.7 or higher, even more preferably 1.75 or higher, and 4.0 or lower, preferably 3.9 or lower, more preferably 3.8 or lower, and even more preferably 3.7 or lower.

[0046] Furthermore, the mass-average molecular weight of component (c) is 90 or more, preferably 110 or more, more preferably 120 or more, even more preferably 130 or more, and 500 or less, preferably 400 or less, more preferably 300 or less, and even more preferably 200 or less.

[0047] Specifically, such component (c) may be one or more selected from alkyl parahydroxybenzoate, isopropylmethylphenol, and parachloromethacresol. In particular, from the viewpoint of forming foam having the above properties well, one or more selected from alkyl parahydroxybenzoate and isopropylmethylphenol are preferred, and isopropylmethylphenol is more preferred.

[0048] From the viewpoint of enabling the formation of foam having the above properties in combination with component (b) and exhibiting an excellent cleaning effect, the content of component (c) in the cleaning agent composition for oral devices of the present invention is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and even more preferably 0.08% by mass or more. Furthermore, from the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibiting of an excellent cleaning effect, the content of component (c) in the cleaning agent composition for oral devices of the present invention is preferably 1% by mass or less, more preferably 0.8% by mass or less, and even more preferably 0.5% by mass or less. And, from the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibiting of an excellent cleaning effect, the content of component (c) in the cleaning agent composition for oral devices of the present invention is preferably 0.01% by mass or more and 1% by mass or less, more preferably 0.05 to 0.8% by mass, and even more preferably 0.08 to 0.5% by mass.

[0049] From the viewpoint of further enhancing the cleaning effect, the cleaning agent composition for oral devices of the present invention preferably further contains polyphosphate or a salt thereof (d). Specifically, such component (d) includes pyrophosphate, tripolyphosphate, tetrapolyphosphate, metaphosphate, and salts thereof.

[0050] From the viewpoint of effectively enhancing the cleaning effect, the content of component (d) in the cleaning agent composition for oral devices of the present invention is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, and even more preferably 0.2% by mass or more. Furthermore, from the viewpoint of enabling the formation of foam having the above properties and ensuring the exhibition of an excellent cleaning effect, the content of component (d) in the cleaning agent composition for oral devices of the present invention is preferably 5% by mass or less, more preferably 4% by mass or less, and even more preferably 3% by mass or less. And, the content of component (d) in the cleaning agent composition for oral devices of the present invention is preferably 0.01% by mass or more and 5% by mass or less, more preferably 0.1 to 4% by mass, and even more preferably 0.2 to 3% by mass.

[0051] The cleaning agent composition for oral devices of the present invention preferably further contains an anionic homopolymer or copolymer (e). The anionic homopolymer or copolymer is a homopolymer or copolymer containing structural units derived from anionic monomers, and by including such component (e), an even better cleaning effect can be achieved. Component (e) may be a homopolymer consisting of structural units derived from only one anionic monomer, a copolymer consisting of structural units derived from two or more anionic monomers, or a copolymer consisting of structural units derived from anionic monomers and structural units derived from monomers other than anionic monomers.

[0052] The mass-average molecular weight of component (e) is preferably 2000 or more, more preferably 5000 or more, and even more preferably 8000 or more, from the viewpoint of effectively enhancing the cleaning effect. Furthermore, more preferably it is 10,000 or more. Also, the mass-average molecular weight of component (e) is preferably 500,000 or less, more preferably 350,000 or less, even more preferably 200,000 or less, and especially preferably 100,000 or less, from the viewpoint of ensuring good solubility or dispersibility of each component. And, the mass-average molecular weight of component (e) is preferably 2,000 or more and 500,000 or less, more preferably 5,000 to 350,000, even more preferably 8,000 to 200,000, and especially preferably 10,000 to 100,000.

[0053] From the viewpoint of greatly contributing to the exhibiting of a cleaning effect, the constituent units of component (e) that are derived from an anionic monomer (e1) having a carboxyl group, a sulfo group, or a phosphate group are preferably constituent units that are derived from an anionic monomer (e1). Specifically, the monomer (e1) that constitutes component (e) can be one or more selected from acrylic acid, methacrylic acid, itaconic acid, maleic acid, fumaric acid, sulfonic acid, styrene sulfonic acid, methacryloyloxyalkyl sulfonic acid, methacrylamidoalkyl sulfonic acid, acryloyloxyalkyl phosphate, and monomers obtained by substituting some of these with anhydrides or alkyl groups, and sugar-derived monomers such as glycopyranose in which a carboxymethyl group is bonded to some of the hydroxyl group. In particular, it is preferable that the monomer does not contain an aromatic ring or alicyclic ring in its molecular structure, and it is more preferable that it is one or more selected from acrylic acid, methacrylic acid, maleic acid, and sulfonic acid.

[0054] From the viewpoint of effectively ensuring excellent cleaning effect, the content of anionic monomer-derived constituent units in 100% by mass of all constituent units of component (e) is preferably 15% by mass or more, more preferably 35% by mass or more, even more preferably 50% by mass or more, and preferably 100% by mass or less.

[0055] Component (e) specifically includes, for example, one or more selected from acrylic acid homopolymer, methacrylic acid homopolymer, crosslinked acrylic acid homopolymer, acrylic acid / maleic acid copolymer, acrylic acid / methacrylic acid copolymer, acrylic acid / sulfonic acid copolymer, vinyl acetate / maleic acid copolymer, phosphinic acid / acrylic acid copolymer, carboxymethylcellulose, xanthan gum, gellan gum, alginic acid, carrageenan, pectin, and hyaluronic acid. Among these, from the viewpoint of exhibiting excellent cleaning effect, one or more selected from acrylic acid homopolymer, acrylic acid / maleic acid copolymer, acrylic acid / methacrylic acid copolymer, and acrylic acid / sulfonic acid copolymer are preferred, one or more selected from acrylic acid / maleic acid copolymer and acrylic acid / sulfonic acid copolymer are more preferred, and acrylic acid / maleic acid copolymer is even more preferred.

[0056] Furthermore, the mass ratio (acrylic acid / maleic acid) of constituent units derived from acrylic acid monomers to constituent units derived from maleic acid monomers that constitute the acrylic acid / maleic acid copolymer is preferably 0.01 to 99, more preferably 0.05 to 50, even more preferably 0.1 to 10, and even more preferably 0.1 to 5.

[0057] From the viewpoint of effectively enhancing the cleaning effect, the content of component (e) in the cleaning agent composition for oral devices of the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, and even more preferably 0.5% by mass or more. Furthermore, from the viewpoint of ensuring good solubility or dispersibility of each component and effectively maintaining the above-mentioned properties of the foam, the content of component (e) in the cleaning agent composition for oral devices of the present invention is preferably 8% by mass or less, more preferably 5% by mass or less, and even more preferably 3% by mass or less. Furthermore, the content of component (e) in the cleaning agent composition for oral devices of the present invention is preferably 0.05 to 8% by mass, more preferably 0.1 to 5% by mass, and even more preferably 0 It is 0.5 to 3% by mass.

[0058] The cleaning agent composition for oral devices of the present invention preferably contains water, from the viewpoint of good dispersion or dissolution of each of the above components, the foam formed exhibits the above properties, and the diffusibility of the cleaning agent composition for oral devices after application to oral devices.

[0059] The water content in the oral appliance cleaning agent composition of the present invention is preferably more than 50% by mass, more preferably 56% by mass or more, even more preferably 60% by mass or more, preferably 99% by mass or less, more preferably 98.5% by mass or less, and even more preferably 98% by mass or less. In this invention, "water" refers to the total water content in the oral appliance cleaning agent composition, including not only purified water directly blended into the composition, but also the water contained in each of the blended components. Furthermore, while "water" in this invention includes water that is pre-blended in the oral appliance cleaning agent composition, if this is not the case, for example, if the composition is diluted with water or dissolved in water before use, it also includes the water used for such dilution or dissolution.

[0060] The cleaning agent composition for oral devices of the present invention may further contain a pH adjuster. This allows for the formation of foam having the above-mentioned properties and the maintenance of a pH that is effective in exhibiting excellent cleaning effects.

[0061] Examples of pH adjusting agents include, specifically, one or more selected from carbonates and bicarbonates; hydroxides; inorganic acids such as hydrochloric acid, sulfuric acid, and nitric acid or their salts; and organic acids such as citric acid, malic acid, lactic acid, tartaric acid, and succinic acid or their salts. Among these, one or more selected from carbonates, bicarbonates, and hydroxides are preferred, one or more selected from sodium carbonate, sodium bicarbonate, sodium sesquicarbonate, sodium hydroxide, potassium carbonate, potassium bicarbonate, potassium sesquicarbonate, and potassium hydroxide are more preferred, and one or more selected from potassium carbonate, potassium bicarbonate, potassium sesquicarbonate, sodium hydroxide, and potassium hydroxide are even more preferred. In this case, the content of the pH adjusting agent is preferably 0.1 to 60% by mass, more preferably 0.1 to 20% by mass, even more preferably 0.15 to 10% by mass, and even more preferably 0.2 to 5% by mass, in the oral appliance cleaning agent composition of the present invention, from the viewpoint of stabilizing the pH of the oral appliance cleaning agent composition of the present invention.

[0062] The cleaning agent composition for oral devices of the present invention may contain, in addition to the above-mentioned components, other components such as anti-inflammatory agents and preservatives; fragrances, pigments, dyes, bleaching agents, enzymes, etc., to the extent that they do not impair the effects of the present invention.

[0063] The pH of the oral appliance cleaning agent composition of the present invention at 25°C is preferably 4.8 or higher, more preferably 5.2 or higher, even more preferably 5.6 or higher, even more preferably 6.2 or higher, even more preferably 8 or higher, preferably 14 or lower, more preferably 13 or lower, even more preferably 12 or lower, and even more preferably 11 or lower, from the viewpoint of effectively enhancing the rapid cleaning effect by the foam having the above-mentioned properties that is formed.

[0064] Furthermore, the present invention relates to the following components (a)~(b): (a) Surfactants: 0.05% by mass or more and 20% by mass or less (b) Hydroxyl group-containing compounds having a ClogP value of -3 or more and 1.4 or less, and a mass-average molecular weight of 35 or more and 800 or less. It contains and the mass ratio of the content of component (b) to the content of component (a) is ((b) / (a)). The present invention provides a cleaning agent composition for oral devices, which cleans oral devices in the form of foam, having a concentration of 0.01 to 30.

[0065] With regard to the embodiments described above, the present invention further discloses the following methods for cleaning oral devices and cleaning compositions for oral devices. [1] A detergent composition containing a surfactant (a) having the following properties (i) and (ii): It forms bubbles, A method for cleaning oral devices, comprising covering the oral device with the resulting foam. (i) Foam specific volume is 7 ml / g or more and 20 ml / g or less, (ii) Drainage rate is 1.6 ml / min or more and 6 ml / min or less [2] The specific volume (i) of the foam formed is preferably 8 ml / g or more, and more preferably A method for cleaning the oral appliance described in [1] above, wherein the concentration is 9 ml / g or more, more preferably 10 ml / g or more, more preferably 19 ml / g or less, more preferably 18 ml / g or less, and even more preferably 17 ml / g or less. [3] A method for cleaning an oral device according to [1] or [2] above, wherein the drainage rate (ii) of the foam formed is preferably 1.9 ml / min or more, more preferably 2 ml / min or more, even more preferably 2.1 ml / min or more, preferably 5 ml / min or less, more preferably 4 ml / min or less, and even more preferably 3 ml / min or less.

[0066] [4] A method for cleaning an oral appliance according to any one of the above [1] to [3], wherein the time for covering the oral appliance with foam is preferably 1 minute or more, more preferably 2 minutes or more, even more preferably 3 minutes or more, preferably 30 minutes or less, more preferably 20 minutes or less, and even more preferably 10 minutes or less. [5] The amount of foam covering the oral appliance is equal to the surface area of ​​the oral appliance per 1 cm². 2 Around there, A method for cleaning any one of the above [1] to [4] oral appliances, wherein the amount is preferably 0.05 g or more, more preferably 0.07 g or more, even more preferably 0.1 g or more, preferably 3.5 g or less, more preferably 3.2 g or less, and even more preferably 3 g or less. [6] A method for cleaning an oral device according to any one of the above [1] to [5], wherein the oral device is covered with the formed foam and then rinsed with water to wash away the cleaning agent composition, or, after covering the oral device with the formed foam, the oral device is rinsed with water to wash away the composition without applying any physical force.

[0067] [7] A method for cleaning an oral device according to any one of the above [1] to [6], wherein a cleaning composition containing a surfactant (a) is filled into a container equipped with a foam-forming mechanism, and foam is formed by spraying or discharging from the container, and the container equipped with the foam-forming mechanism is preferably a trigger-type spray container or a pump-type dispenser container. [8] In a trigger-type spray container, it is desirable to set the spray diameter at a spray distance of 20 cm to preferably 2 cm or more, more preferably 3 cm or more, more preferably 10 cm or less, and more preferably 8 cm or less, and the spray force at a spray distance of 20 cm to preferably 1 g·f or more, more preferably 3 g·f or more, more preferably 10 g·f or less, and more preferably 8 g·f or less, for the cleaning method of an intraoral device as described in [7] above. [9] Component (a) is one or more selected from anionic surfactants (a1), amphoteric surfactants (a2), and nonionic surfactants (a3), with a preference for one or more selected from anionic surfactants (a1) and amphoteric surfactants (a2), or a preference for a combination of anionic surfactants (a1) and amphoteric surfactants (a2), more preferably one or more selected from alkyl sulfate esters, acyl amino acid salts, and alkylamine oxides, and even more preferably one or more selected from alkyl sulfate esters and alkylamine oxides, any of the above [1] to [8]. Method for cleaning oral appliances (1).

[0068]

[10] A cleaning agent composition containing a surfactant (a) for forming foam and covering an oral appliance with the foam to clean the oral appliance, The bubbles that are formed are (i) and (ii) below: (i) Foam specific volume is 7 ml / g or more and 20 ml / g or less, (ii) Drainage rate is 1.6 ml / min or more and 6 ml / min or less A cleaning agent composition for oral appliances having the following properties.

[11] The cleaning agent composition for oral devices according to

[10] above, wherein the content of component (a) is preferably 0.05% by mass or more, more preferably 0.15% by mass or more, even more preferably 0.5% by mass or more, even more preferably 0.7% by mass or more, preferably 20% by mass or less, more preferably 15% by mass or less, even more preferably 5% by mass or less, and even more preferably 3% by mass or less.

[12] The cleaning agent composition for oral devices according to

[10] or

[11] above, further comprising a hydroxyl group-containing compound (b) having a ClogP value of -3 or more and 1.4 or less and a mass average molecular weight of 35 or more and 800 or less, wherein the ClogP value is preferably -2.8 or more, more preferably -2.6 or more, even more preferably -2.5 or more, preferably 1.37 or less, more preferably 1.35 or less, and even more preferably 1.3 or less.

[13] A cleaning agent composition for oral devices according to any one of

[10] to

[12] above, wherein the content of component (b) is preferably 0.1% by mass or more, more preferably 0.3% by mass or more, even more preferably 0.5% by mass or more, even more preferably 0.6% by mass or more, preferably 30% by mass or less, more preferably 15% by mass or less, even more preferably 9% by mass or less, and even more preferably 7% by mass or less.

[14] The oral appliance cleaning composition according to

[12] or

[13] above, wherein the mass ratio ((b) / (a)) of the content of component (b) to the content of component (a) is preferably 0.01 or more, more preferably 0.05 or more, even more preferably 0.1 or more, preferably 30 or less, more preferably 15 or less, even more preferably 8 or less, and even more preferably 4 or less.

[0069]

[15] A cleaning agent composition for oral devices according to any one of the above

[10] to

[14] , further containing an aromatic compound (c) having a ClogP value of 1.5 or more and 4.0 or less and a mass average molecular weight of 90 or more and 500 or less, wherein the ClogP value is preferably 1.6 or more, more preferably 1.7 or more, even more preferably 1.75 or more, preferably 3.9 or less, more preferably 3.8 or less, and even more preferably 3.7 or less.

[16] The cleaning agent composition for oral devices according to

[15] above, wherein the content of component (c) is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, even more preferably 0.08% by mass or more, preferably 1% by mass or less, more preferably 0.8% by mass or less, and even more preferably 0.5% by mass or less. [Examples]

[0070] The present invention will be described in detail below based on examples. Unless otherwise specified in the table, the content of each component is expressed in mass percent.

[0071] [Examples 1-20, Comparative Examples 1-4] Each of the components listed in Table 1 was mixed to prepare a cleaning agent composition for each oral appliance. The obtained cleaning agent compositions for oral appliances were filled into a trigger-type spray container (spray diameter: 5 cm at a spray distance of 20 cm, spray force: 5 g·f), and each was evaluated according to the method described below. The results are shown in Tables 1 and 2.

[0072] 《Foam ratio》 15 g of foam formed by spraying each oral appliance cleaning agent composition filled in a trigger-type spray container was placed into a 200 ml graduated cylinder (Nikko Hansen Co., Ltd., material: PMMA, manufacturer model number: 30-0106-55), and the foam volume (ml) was measured. Based on the obtained value, the foam specific volume (ml / g) was calculated. The measurement temperature was 25°C.

[0073] Drainage rate 15g of foam formed by spraying each oral appliance cleaning agent composition, which was filled into a trigger-type spray container, was poured into a 200ml cylinder (manufactured by Nikko Hansen, material: polymethyl methacrylate, manufacturer model number: 30-0106-55). The time from immediately after pouring until the drainage reached a height of 10ml was measured, and the drainage rate (ml / min) was calculated based on the obtained value. The measurement temperature was 25°C.

[0074] Cleaning effectiveness (visual assessment) Model stains (by Sudan III) on a whiteboard (1cm square) made of polymethyl methacrylate resin. 0.1 ml of red-colored rapeseed oil was uniformly applied and placed on the bottom of the beaker. Next, 3 g of foam formed by spraying each oral appliance cleaning agent composition, which was filled into a trigger-type spray bottle, three times from the top of the beaker was placed on top and left to stand for 5 minutes. After the whiteboards were left to stand, they were removed and rinsed with water. The amount of dirt remaining on the surface of the whiteboards was visually inspected and evaluated according to the following criteria, and the average value obtained by two panelists was used as an indicator for evaluating the cleaning effect. 1: Almost no dirt remains on the whiteboard surface. 2: More than 75% of the dirt on the whiteboard surface was removed. 3: More than 50% of the whiteboard surface was stained.

[0075] Cleaning effectiveness (average dirt residue rate (%)) Model stains (by Sudan III) on a whiteboard (1cm square) made of polymethyl methacrylate resin. 0.1 ml of red-colored rapeseed oil was applied uniformly. Next, the white board coated with this model stain was placed on the bottom of a beaker. Then, from the top of the beaker, three sprays of each oral appliance cleaning agent composition, filled in a trigger-type spray bottle, were applied to form 3 g of foam. This foam was placed on top to cover the model stain and left to stand for 5 minutes. After the model had settled, the whiteboard covered in foam and stained with dirt was removed and rinsed with water. Then, it was placed on a stand with the side that still had dirt facing upwards, and photographed with a fixed camera (DR-5, Nikon). Next, the captured image was separated into RGB using analysis software (WinROOF version 6.6). The images were then separated into RGB components and binarized. The percentage of remaining dirt on the whiteboard was calculated from the proportion of the binarized images. The threshold for binarization was set between a lower limit of 50 and an upper limit of 160. This procedure was repeated for three whiteboards, and the average value was taken as the average percentage of remaining dirt.

[0076] [Table 1]

[0077] [Table 2]

[0078] Examples of formulations for the cleaning agent composition for oral devices of the present invention are shown below. The foam specific volume and drainage rate were determined by the same method as described above. These cleaning compositions for oral devices can be filled into a container equipped with a foam-forming mechanism and then used, for example, in the following cleaning methods. • A method in which a complete denture is placed in a cup, and then a cleaning composition is sprayed or dispensed onto the oral appliance to coat it with foam, and then rinsed with water. A method of placing a partial denture inside a cap attached to a container containing a cleaning agent composition, spraying or dispensing the cleaning composition towards the oral appliance to coat the oral appliance with foam, and then rinsing with water.

[0079] [Table 3]

[0080] [Prescription Example 9] TIFF0007867939000004.tif77170

[0081] [Prescription Example 10] TIFF0007867939000005.tif69170

[0082] [Prescription Example 11] TIFF0007867939000006.tif62170

[0083] [Prescription Example 12] TIFF0007867939000007.tif76170

[0084] [Prescription Example 13] TIFF0007867939000008.tif61170

[0085] [Prescription Example 14] TIFF0007867939000009.tif69170

Claims

1. A cleaning agent composition for cleaning oral devices by forming foam and coating the oral devices with the resulting foam, Surfactant (a) is present in an amount of 0.05% by mass or more and 20% by mass or less, A hydroxyl group-containing compound (b) having a ClogP value of -3 or more and 1.4 or less, and a mass-average molecular weight of 35 or more and 800 or less, in an amount of 0.1% to 9% by mass. Contains, The mass ratio ((b) / (a)) of the content of the hydroxyl group-containing compound (b) to the content of the surfactant (a) is 0.8 or more and 8.8 or less. Component (a) is one or more anionic surfactants selected from alkyl sulfate salts, alkyl sulfonates, acyl amino acid salts, N-methyl long-chain acyl taurine salts, and fatty acid salts (a1), one or more amphoteric surfactants selected from alkylamine oxides, betaine acetate, imidazolinium betaine, alkyl sulfobetaine, and coconut oil fatty acid amide alkyl betaine (a2), and one or more nonionic surfactants selected from glycerin fatty acid esters, alkyl glucosides, polyglycerin fatty acid esters, and polyoxyethylene alkylphenyl ethers (a3). A cleaning agent composition for oral devices, wherein component (b) is one or more selected from propylene glycol, butylene glycol, dipropylene glycol, ethylene glycol, diethylene glycol monobutyl ether, benzyl alcohol, and phenoxyethanol.

2. Furthermore, the cleaning agent composition for oral devices according to claim 1, further comprising one or more aromatic compounds (c) selected from alkyl parahydroxybenzoate and isopropylmethylphenol.

3. The cleaning agent composition for oral appliances according to claim 1 or 2, wherein the content of component (c) is 0.01% by mass or more and 1% by mass or less.

4. A cleaning agent composition for oral devices according to any one of claims 1 to 3, wherein component (a) is one or more selected from anionic surfactants (a1) and amphoteric surfactants (a2).

5. The cleaning agent composition for oral devices according to claim 4, wherein component (a) is one or more selected from alkyl sulfate ester salts, acyl amino acid salts, and alkylamine oxides.

6. A cleaning agent composition for oral devices according to any one of claims 1 to 5, which is filled into a trigger-type spray container or a pump-type dispenser container.

Images