Oligonucleotide labeling processing device

JP7871898B2Active Publication Date: 2026-06-09SHIMADZU SEISAKUSHO LTD

Patent Information

Authority / Receiving Office
JP Β· JP
Patent Type
Patents
Current Assignee / Owner
SHIMADZU SEISAKUSHO LTD
Filing Date
2022-12-01
Publication Date
2026-06-09

Smart Images

  • Figure 0007871898000001
    Figure 0007871898000001
  • Figure 0007871898000002
    Figure 0007871898000002
Patent Text Reader

Abstract

An oligonucleotide display processing device according to the present invention comprises: an input reception unit (34) that receives input of base information, sugar information, and phosphate group information of each of a plurality of nucleotides forming a target oligonucleotide, and arrangement information of the plurality of nucleotides; a storage unit (35) having pre-stored therein labels which each include at least one of a character or a symbol, and which are base labels corresponding to the base information, sugar labels corresponding to the sugar information, and phosphate group labels corresponding to the phosphate group information; an extraction unit (45) that extracts, from the storage unit, base labels, sugar labels, and phosphate group labels respectively corresponding to the base information, the sugar information, and the phosphate group information received by the input reception unit; and an output unit (46) that arranges, on the basis of the arrangement information of each of the nucleotides, the base labels, the sugar labels, and the phosphate group labels of the plurality of nucleotides extracted by the extraction unit, and disposes and displays, on a display unit (24), the base labels, the sugar labels, and the phosphate group labels of the respective nucleotides such that base labels of adjacent nucleotides are arranged side by side. The present invention enables easy understanding of the structure of oligonucleotides.
Need to check novelty before this filing date? Find Prior Art

Claims

1. A storage unit in which labels containing letters and symbols corresponding to the bases, sugars, and phosphate groups of multiple types of nucleotides, as well as sugar modifications, are pre-stored, including base labels, sugar labels, phosphate group labels, and labels indicating sugar modifications. An input receiving unit that receives input of base information including the type of base and whether or not modifications are present in each of the multiple nucleotides constituting the oligonucleotide to be processed, sugar information including the type of sugar and whether or not modifications are present in the sugar, phosphate group information including the type of phosphate group and whether or not modifications are present in the phosphate group, and sequence information of the multiple nucleotides, An extraction unit extracts from the storage unit base labels, sugar labels, labels indicating sugar modification, and phosphate group labels corresponding to the base information, sugar information, and phosphate group information of the plurality of nucleotides received by the input receiving unit, respectively. The extraction unit arranges the base label, sugar label, sugar modification label, and phosphate group label of each of the plurality of nucleotides extracted by the extraction unit according to the sequence information for each nucleotide, and displays the base label, sugar label, phosphate group label, and sugar modification label of each nucleotide on the display unit, with the base labels of adjacent nucleotides aligned. It has, An oligonucleotide labeling apparatus, wherein for each nucleotide, a base label is placed at a first relative position to a sugar label, a phosphate group label is placed at a second relative position different from the first relative position, and a label indicating sugar modification is placed at a third relative position different from the first and second relative positions, at a position different from the direction in which the phosphate group of the adjacent nucleotide is located.

2. The oligonucleotide display apparatus according to claim 1, wherein the output unit arranges the base labels of adjacent nucleotides in a horizontal direction, and the base label, sugar label, and phosphate group label of each nucleotide in order from top to bottom.

3. The oligonucleotide display apparatus according to claim 1, wherein at least one of the base label, the sugar label, and the phosphate group label includes a figure.

4. The oligonucleotide display apparatus according to claim 1, wherein at least one of the letters and symbols is arranged inside a predetermined figure, and the predetermined figure is different from the base label, the sugar label, and the phosphate group label.

5. A program that causes a computer to function as an oligonucleotide display processing device according to any one of claims 1 to 4.