Pharmaceutical preparations
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- ROHTO PHARM CO LTD
- Filing Date
- 2021-05-28
- Publication Date
- 2026-06-17
AI Technical Summary
Conventional gastrointestinal drugs containing sodium-based antacids and belladonna extract are not suitable for the elderly or those with reduced physical strength, as they can raise blood pressure and cause anticholinergic effects, and their formulation stability is impaired when these components are excluded.
Formulating gastrointestinal medications with calcium-based and magnesium-based antacids, along with digestive enzymes, to improve stability in formulations that exclude sodium-based antacids and belladonna extract, enhancing adhesion, hygroscopicity, and turbidity in aqueous media.
The formulation achieves improved stability, preventing adhesion, hygroscopicity, and turbidity issues, ensuring effective absorption and maintaining the quality of the active ingredients, making it suitable for the elderly and those with underlying health conditions.
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