Hair care composition

Abstract

Disclosed is a hair care composition comprising an antidandruff agent selected from piroctone olamine, climbazole, ketoconazole, selenium sulfide and mixtures thereof, a copolymer comprising acrylamidopropyltrimonium chloride, and a cationic guar polymer having a molecular weight of 300,000-2,500,000 Daltons and a degree of cationic substitution of 0.05-0.4, wherein the weight ratio of the amount of copolymer to the amount of cationic guar polymer is in the range of 1:10 to 10:1.

Description

[Technical Field]

[0001] The present invention relates to a hair care composition, and more particularly to a hair care composition comprising an anti-dandruff agent and a combination of a copolymer containing acrylamidopropyltrimonium chloride and a cationic guar polymer. [Background technology]

[0002] Hair care compositions generally provide cleansing benefits, conditioning benefits, or a combination of both. Such compositions typically contain one or more cleansing surfactants that generally help cleanse the hair and scalp to remove undesirable dirt, particles, and grease.

[0003] Dandruff control is an important aspect of hair cleansing and care. The benefits of dandruff prevention have been provided by hair care compositions, including shampoos and hair conditioners. Dandruff is a problem that affects many people around the world. This condition manifests as clumps of dead skin cells shedding from the scalp. These are white and give an aesthetically unpleasant appearance. One factor contributing to dandruff is certain members of the Malassezia yeast. To combat these, anti-dandruff products contain certain anti-dandruff agents with antifungal activity, such as piroctone olamine (Octopirox®), selenium sulfide, or a combination thereof. These anti-dandruff agents remove Malassezia from the scalp (or at least reduce its levels) and treat the dandruff condition gently and effectively. Such products function as hair cleansing shampoos or hair conditioners while simultaneously reducing the causes of dandruff.

[0004] However, many anti-dandruff products do not adequately deposit anti-dandruff agents onto the scalp. These anti-dandruff agents do not adhere strongly to the scalp surface and are easily washed away during shampooing or showering, resulting in little to no anti-dandruff effect. Consequently, there is a demand for hair care compositions that improve anti-dandruff deposition and maximize the effectiveness of such agents.

[0005] The inventors unexpectedly discovered that a combination of a copolymer containing acrylamidopropyltrimonium chloride and a cationic guar polymer can increase the deposition of anti-dandruff agents while providing the desired sensory experience.

[0006] Tests and definitions Hair care composition As used herein, “hair care composition” means a composition for topical application to the hair and / or scalp of mammals, particularly humans. Such compositions can generally be classified as leave-on or rinse-off and include any product applied to the human body to improve appearance, cleansing, odor control, or overall aesthetics. The compositions of the present invention may be in the form of a liquid, lotion, cream, foam, scrub, gel, or bar. Non-limiting examples of such compositions include leave-on hair lotions, creams, and rinse-off shampoos, conditioners, shower gels, or cosmetic bars. The compositions of the present invention are preferably rinse-off compositions, particularly preferably shampoos or conditioners, and most preferably shampoos.

[0007] Cation charge density As used herein, “cation charge density” refers to the number of cation charges per unit weight of a given polymer. The cation charge density can be calculated from the degree of substitution described in International Publication No. 2013 / 011122, particularly on page 8, lines 8-17, which is incorporated herein by reference in its entirety. For example, in the case of a cationic guar polymer obtained by reaction with 2,3-epoxypropyltrimethylammonium chloride, the cation charge density can be calculated from the degree of substitution using the following formula:

[0008] Cation charge density (milliequivalent per gram (meq / g)) =

number

[0009] molecular weight As used herein, "molecular weight" refers to the weight-average molecular weight of a given polymer. The weight-average molecular weight (WAVGMW) of a given polymer is measured by size exclusion chromatography (SEC) analysis using absolute calibration (universal calibration). Polysaccharide standards pullulan and dextran were used for calibration.

[0010] others Except as in the examples, or unless otherwise expressly indicated, all figures in this specification indicating the quantities or reaction conditions of materials, the physical properties of materials and / or their use may be understood to be modified by the term “approximately”.

[0011] All quantities are based on the weight of the final hair care composition unless otherwise specified.

[0012] When clarifying any range of values, please note that any specific upper limit can be associated with any specific lower limit.

[0013] To avoid misunderstanding, the term "comprising" is intended to mean "including," but not necessarily "consisting of" or "composed of." In other words, the listed steps or options do not need to be exhaustive.

[0014] Notwithstanding the fact that the claims may appear to be non-multiple dependent or non-repeating, the disclosures of the present invention as presented herein should be considered to encompass all embodiments as multiple dependents of each other.

[0015] When features are disclosed with respect to a particular aspect of the present invention (e.g., a composition of the present invention), such disclosure should be considered to be applicable by analogy to any other aspect of the present invention (e.g., a method of the present invention).

Prior Art Documents

Patent Documents

[0016]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0017] In a first aspect, the present invention relates to a hair care composition comprising: (a) an anti-dandruff agent selected from piroctone olamine, climbazole, ketoconazole, selenium sulfide, and mixtures thereof; (b) a copolymer comprising acrylamidopropyltrimonium chloride; (c) a cationic guar polymer having a molecular weight of 300,000 to 2,500,000 daltons and a cationic substitution degree of 0.05 to 0.4, and the composition is targeted, wherein the weight ratio of the amount of the copolymer to the amount of the cationic guar polymer is in the range of 1:10 to 10:1. The composition is targeted, wherein the weight ratio of the amount of the copolymer to the amount of the cationic guar polymer is in the range of 1:10 to 10:1.

[0018] In a second aspect, the present invention is directed to a non-therapeutic method of depositing an anti-dandruff agent on the scalp, the method comprising applying a hair care composition according to any embodiment of the first aspect of the present invention to the surface of an individual's scalp. This method is preferably for non-therapeutic benefits.

[0019] In a third aspect, the present invention relates to the use of a combination of an acrylamidopropyltrimonium chloride / acrylamide copolymer and a cationic guar polymer to increase the deposition of an anti-dandruff agent on the scalp.

[0020] All other aspects of the present invention will become more readily apparent upon consideration of the following detailed description and examples. [Modes for carrying out the invention]

[0021] A copolymer containing acrylamidopropyltrimonium chloride A copolymer suitable for use in the compositions of the present invention comprises acrylamidopropyltrimonium chloride. Preferably, the copolymer also comprises acrylamide in addition to acrylamidopropyltrimonium chloride. A particularly preferred copolymer is a copolymer of acrylamidopropyltrimonium chloride and acrylamide.

[0022] The copolymer according to the present invention preferably has a charge density of 1.0 to 3.0 milliequivalents / gram (meq / g), more preferably 1.1 to 2.5 meq / g, even more preferably 1.2 to 2.5 meq / g, and most preferably 1.3 to 2.5 meq / g. The copolymer preferably has a molecular weight of 100,000 to 3,000,000 grams / mol (g / mol), more preferably 500,000 to 2,800,000 g / mol, even more preferably 800,000 to 2,500,000 g / mol, and most preferably 1,000,000 to 2,500,000 g / mol. An example of a suitable copolymer is commercially available from Ashland under the trade name N-Hance SP-100 (registered trademark). N-Hance SP-100 (registered trademark) has a charge density of 1.8 to 2.2 meq / g and a molecular weight of 1,800,000 to 2,200,000 g / mol.

[0023] The hair care composition of the present invention typically contains the copolymer in an amount comprising 0.001 to 2%, more preferably 0.01 to 1%, even more preferably 0.01 to 0.8%, most preferably 0.05 to 0.5%, and all ranges encompassed therein, based on the total weight of the hair care composition.

[0024] Cationic guar polymer The composition also includes a cation-modified guar polymer having a molecular weight of 300,000 to 2,500,000 daltons and a degree of cation substitution of 0.05 to 0.4.

[0025] The cation-modified guar polymer preferably has a molecular weight of 1,000,000 to 2,300,000 daltons, more preferably 1,000,000 to 1,500,000 daltons.

[0026] The cationic guar polymer preferably has a degree of cationic substitution of 0.1 to 0.3, more preferably 0.16 to 0.2.

[0027] The cation-modified guar polymer most preferably has a molecular weight of 1,000,000 to 1,500,000 daltons and a degree of cation substitution (DS) of 0.16 to 0.20. This DS value corresponds to a charge density of 0.85 to 1.05.

[0028] The cationic guar polymer is preferably guar hydroxypropyltrimonium chloride. The guar polymer mainly contains galactomannan polymer chains. This polymer is available in various molecular weights and degrees of cationic substitution depending on the degree of hydrolysis and cationization of the guar.

[0029] Generally, in cationic polysaccharide polymers, the hydroxyl groups of the unmodified monomeric sugar ring units are the sites for cationic substitution. The degree of substitution (DS) is typically in the range of 0–3, due to the fact that most polysaccharide monomeric sugar units have an average of three hydroxyl groups available for substitution. In addition to DS, the cationic charge on the polymer can also be quantified as the cationic charge density. DS has been measured by various methods in the past. For example, the cationic charge density of a polymer is sometimes calculated based on the nitrogen content measured via the Kjeldahl method under a chemical test of nitrogen measurement, as described in the United States Pharmacopeia, and expressed in milliequivalents per gram (meq). However, the cationic charge density of the polymer in this invention is calculated from the degree of substitution measured by 1H NMR in a solvent mixture of deuterium oxide (D2O) and deuterium chloride (DCl).

[0030] In many cases, comparing DS obtained from 1H NMR measurements with DS obtained from the Kjeldahl method is not advisable due to the fact that the two methods are affected by different factors.

[0031] Within the wide range of molecular weights available for guar, the cationic guar used in this invention has a molecular weight that is considered "medium." Within the wide range of charge densities, the above range used in this invention is considered "medium." The cationic modified guar deposited polymer is present in the composition in an amount of preferably 0.001 to 2% by weight, more preferably 0.01 to 1% by weight, 0.04 to 0.5% by weight, and more preferably 0.08 to 0.25% by weight.

[0032] The ratio of the amount of copolymer to the amount of cationic guar polymer in the composition of the present invention is in the range of 1:10 to 10:1, preferably 1:5 to 5:1, and more preferably 1:3 to 3:1.

[0033] Dandruff control The hair care composition contains an anti-dandruff agent, which is a compound that is active against dandruff, is typically an antibacterial agent, and preferably an antifungal agent. Suitable anti-dandruff agents that can be used in the present invention are selected from piroctone olamine (Octopirox®), crimbazole, ketoconazole, selenium sulfide, and mixtures thereof. In preferred embodiments, the anti-dandruff agent is selected from piroctone olamine (Octopirox®) and crimbazole. In particularly preferred embodiments, the anti-dandruff agent is piroctone olamine.

[0034] Typically, the hair care composition of the present invention typically contains an anti-dandruff agent in an amount comprising 0.01 to 10%, more preferably 0.01 to 5%, even more preferably 0.05 to 2%, most preferably 0.05 to 1.5%, and all ranges encompassed therein, based on the total weight of the hair care composition.

[0035] The combination of the copolymer of the present invention and a cationic guar polymer has been found to unexpectedly increase the deposition of the anti-dandruff agent. The composition preferably contains the copolymer and the anti-dandruff agent in a weight ratio of 1:10 to 1:1, preferably 1:5 to 1:1, and most preferably 1:4 to 1:1.5.

[0036] The pH of the composition is preferably 4.0 or higher, and more preferably in the range of 4.0 to 7.0.

[0037] The hair care composition preferably includes other cationic polymers in addition to the copolymer. Suitable cationic polymers may be homopolymers or formed from two or more monomers. The molecular weight of the polymer is generally between 5,000 and 10,000,000 g / mol, typically at least 10,000 g / mol, preferably 100,000 to 2,000,000 g / mol. The polymer has cationic nitrogen-containing groups such as quaternary ammonium or protonated amino groups, or mixtures thereof. Cationic nitrogen-containing groups are generally present as substituents on some of the total monomer units of the cationic polymer. Therefore, if the polymer is not a homopolymer, it may contain spacer non-cationic monomer units. The ratio of cationic monomer units to non-cationic monomer units is selected to obtain a polymer with a cationic charge density within the required range.

[0038] Suitable cationic polymers include, for example, copolymers of vinyl monomers having cationic amines or quaternary ammonium functional groups with water-soluble spacer monomers such as (meth)acrylamide, alkyl and dialkyl(meth)acrylamide, alkyl(meth)acrylate, vinylcaprolactone, and vinylpyrrolidine. The alkyl and dialkyl-substituted monomers preferably have C1-C7 alkyl groups, more preferably C1-C3 alkyl groups. Other suitable spacers include vinyl esters, vinyl alcohols, maleic anhydride, propylene glycol, and ethylene glycol.

[0039] Preferably, the cationic polymer is a cationic polysaccharide polymer such as cationic guar, cationic starch, and cationic cellulose. Preferably, such a cationic polysaccharide polymer has a molecular weight of 100,000 g / mol to 2,300,000 g / mol, more preferably 150,000 g / mol to 2,000,000 g / mol. Such a cationic polysaccharide polymer preferably has a cationic charge density of 0.1 to 4 meq / g.

[0040] Cationic polysaccharide polymers suitable for use in the compositions of the present invention include the general formula: A-O-[R ,

[0042] , 3 , , 4 , , ,

[0041] -N + (R 2 )(R 3 )(R 4 )X - wherein A is an anhydroglucose residue such as a starch or cellulose anhydroglucose residue. Examples include those represented by the formula. R 1 is an alkylene group, oxyalkylene group, polyoxyalkylene group, hydroxyalkylene group, or a combination thereof. R 2 , R 3 and R 4 independently represent an alkyl group, aryl group, alkylaryl group, arylalkyl group, alkoxyalkyl group or alkoxyaryl group, and each group contains up to about 18 carbon atoms. The total number of carbon atoms in each cationic moiety (i.e., the total of the carbon atoms of R 2 , R 3 and R 4 ) is preferably about 20 or less, and X is an anionic counterion.

[0041] Cationic cellulose is available from Amerchol Corp. (Edison, NJ) as salts of hydroxyethyl cellulose reacted with trimethylammonium-substituted epoxides, called Polyquaternium 10 in the industry (CTFA), from the Polymer JR(trademark) and LR(trademark) series of polymers. Another type of cationic cellulose includes quaternary ammonium salt polymers of hydroxyethyl cellulose reacted with lauryldimethylammonium-substituted epoxides, called Polyquaternium 24 in the industry (CTFA). These materials are available from Amerchol Corp. (Edison, NJ) under the trade name Polymer LM-200.

[0042] ​Other suitable cationic polysaccharide polymers include quaternary nitrogen-containing cellulose ethers (e.g., as described in U.S. Patent No. 3,962,418) and copolymers of etherified cellulose and starch (e.g., as described in U.S. Patent No. 3,958,581).

[0043] When used, the cationic polymer is generally present in the hair care composition of the present invention in an amount including 0.001 to 1% by weight, more preferably 0.01 to 0.5% by weight, most preferably 0.03 to 0.3% by weight, and all ranges encompassed therein, based on the total weight of the hair care composition.

[0044] The hair care composition may further contain conditioning agents to provide conditioning benefits. Preferably, the hair care composition has an average droplet diameter (D) of less than 15 microns, preferably less than 10 microns, more preferably less than 5 microns, and most preferably less than 3 microns. 3,2 The dispersion droplets contain a water-insoluble conditioning agent having the average droplet diameter (D) of the water-insoluble conditioning agent. 3,2 ) may also be measured by laser light scattering techniques, for example, using a 2600D Particle Sizer from Malvern Instruments.

[0045] The water-insoluble conditioning agent may include a non-silicone conditioning agent containing a non-silicone oil or fatty material such as hydrocarbon oils, fatty esters, and mixtures thereof. Preferably, the water-insoluble conditioning agent is an emulsified silicone oil.

[0046] Suitable silicones include polydiorganosiloxanes, particularly polydimethylsiloxane having the CTFA name dimethicone. Furthermore, polydimethylsiloxane having the CTFA name dimethiconol and a hydroxyl-terminated group is particularly suitable for use in the compositions of the present invention (especially shampoos and conditioners). Silicone gums with a slight degree of crosslinking, for example as described in International Publication No. 96 / 31188, are also suitable for use in the compositions of the present invention. Preferably, the silicone oil contains dimethicone, dimethiconol, or a mixture thereof.

[0047] Suitable emulsified silicones for use in the hair care compositions of the present invention are available as preformed silicone emulsions from silicone suppliers such as Dow Corning and GE Silicone. The use of such preformed silicone emulsions is preferred because the processing and control of silicone particle size are easy. Such preformed silicone emulsions typically further contain a suitable emulsifier and can be prepared by a chemical emulsification process such as emulsion polymerization, or by mechanical emulsification using a high-shear mixer. Examples of suitable preformed silicone emulsions include DC1785, DC1788, and DC7128, all available from Dow Corning. These are dimethiconol / dimethicone emulsions.

[0048] Another classification of silicones that can be used is functionalized silicones, such as amino-functional silicones, which means silicones containing at least one primary, secondary, or tertiary amine group or a quaternary ammonium group. A suitable example of an amino-functional silicone is a polysiloxane having the CTFA name "amodimethicone".

[0049] The water-insoluble conditioning agent is generally present in the hair care composition of the present invention in an amount of 0.05 to 15%, preferably 0.1 to 10%, more preferably 0.5 to 8%, most preferably 1 to 5%, and all ranges encompassed thereto, based on the total weight of the hair care composition.

[0050] In a preferred embodiment, the hair care composition is a shampoo. Therefore, in a preferred embodiment, the composition contains a cleansing surfactant. Non-limiting examples of preferred anionic cleansing surfactants include alkyl sulfates, alkyl ether sulfates, alkaryl sulfonates, alkanoyl isethionates, alkyl succinates, alkyl sulfosuccinates, alkyl ether sulfosuccinates, N-alkyl sarcosinates, alkyl phosphates, alkyl ether phosphates and alkyl ether carboxylic acids and their salts, particularly their sodium, magnesium, ammonium and mono-, di- and triethanolamine salts. The alkyl and acyl groups generally contain 8 to 18 carbon atoms, preferably 10 to 16, and may be unsaturated. Alkyl ether sulfates, alkyl ether sulfosuccinates, alkyl ether phosphates and alkyl ether carboxylic acids and their salts may contain 1 to 20 ethylene oxide or propylene oxide units per molecule. Typical anionic cleaning surfactants used in the compositions of the present invention include, but are not limited to, sodium oleylsuccinate, ammonium lauryl sulfosuccinate, sodium lauryl sulfate, sodium lauryl ether sulfate, sodium lauryl ether sulfosuccinate, ammonium lauryl sulfate, sodium dodecylbenzenesulfonate, triethanolamine dodecylbenzenesulfonate, sodium cocoyl isethionate, sodium lauryl isethionate, lauryl ether carboxylic acid, sodium N-lauryl sarcosinate, or mixtures thereof. Preferred anionic cleaning surfactants are alkyl sulfates and alkyl ether sulfates. Preferred alkyl sulfates are C 8-18 Alkyl sulfate, more preferably C 12-18The surfactant is an alkyl sulfate, preferably in the form of a salt with a solubilizing cation such as sodium, potassium, ammonium, or substituted ammonium. Examples include sodium lauryl sulfate (SLS) or sodium dodecyl sulfate (SDS). It is particularly preferable that the anionic cleaning surfactant is an alkyl ether sulfate. A preferred alkyl ether sulfate is of the formula: RO(CH2CH2O) n SO3M, in the formula, is an alkyl or alkenyl having 8 to 18 (preferably 12 to 18) carbon atoms, n is a number having an average value of at least 0.5, preferably between 1 and 3, more preferably between 2 and 3, and M is a solubilizing cation such as sodium, potassium, ammonium, or substituted ammonium. One example is sodium lauryl ether sulfate (SLES). A preferred alkyl ether sulfate is sodium lauryl ether sulfate having an average ethoxylation degree of 0.5 to 3, preferably 1 to 3, more preferably 2 to 3.

[0051] Anionic cleansing surfactants are typically present in the hair care composition of the present invention at a level of 0.5 to 45%, more preferably 1.5 to 35%, most preferably 5 to 20%, and all ranges encompassed thereto, based on the total weight of the hair care composition.

[0052] The compositions according to the present invention may be made milder by preferably further containing co-surfactants such as amphoteric surfactants and zwitterionic surfactants. Preferred examples include alkylamine oxides, alkyl betaines, alkylamidopropyl betaines, alkyl sulfobetaines (sultaines), alkyl amphoacetates, alkyl amphopropionates, and alkylamidopropyl hydroxysultaines, where the alkyl group has 8 to 19 carbon atoms. Preferably, the co-surfactant is a betaine surfactant. Cocamidopropyl betaine (CAPB) is particularly preferred.

[0053] When used, the co-surfactant typically constitutes 0.1 to 15% by weight, more preferably 0.5 to 8% by weight, and most preferably 0.5 to 4% by weight of the hair care composition, based on the total weight of the hair care composition, and includes all ranges encompassed therein.

[0054] Preferably, the composition of the present invention further comprises a suspending agent. Suitable suspending agents are selected from polyacrylic acid, crosslinked polymers of acrylic acid, copolymers of acrylic acid and hydrophobic monomers, copolymers of carboxylic acid-containing monomers and acrylic acid esters, crosslinked copolymers of acrylic acid and acrylate esters, heteropolysaccharide gums, and crystalline long-chain acyl derivatives. The long-chain acyl derivatives are preferably selected from ethylene glycol stearate, fatty acid alkanolamides having 16 to 22 carbon atoms, and mixtures thereof. Ethylene glycol distearate and polyethylene glycol 3-distearate are preferred long-chain acyl derivatives because they impart a pearly luster to the composition. Polyacrylic acid is commercially available as Carbopol 420, Carbopol 488, or Carbopol 493. Polymers of acrylic acid crosslinked with polyfunctional agents may also be used. These are commercially available as Carbopol 910, Carbopol 934, Carbopol 941, and Carbopol 980. A suitable copolymer of a carboxylic acid-containing monomer and an acrylic acid ester is Carbopol 1342. All Carbopol® materials are available from Goodrich.

[0055] Suitable crosslinking polymers for acrylic acid and acrylate esters are Pemulen TR1 or Pemulen TR2. A suitable heteropolysaccharide gum is xanthan gum, which is available, for example, as Kelzan mu.

[0056] A mixture of any of the above suspending agents may be used. Preferably, it is a mixture of a crosslinked polymer of acrylic acid and a crystalline long-chain acyl derivative.

[0057] The suspending agent is generally present in the hair care composition of the present invention in an amount of 0.1 to 10%, more preferably 0.2 to 6%, most preferably 0.3 to 4%, and all ranges encompassed thereto, based on the total weight of the hair care composition.

[0058] Furthermore, preservatives may be incorporated into the hair care composition of the present invention to protect against the growth of potentially harmful microorganisms. Conventional and suitable preservatives include alkyl esters of parahydroxybenzoic acid, hydantoin derivatives, propionates, and various quaternary ammonium compounds. Exemplary and non-limiting examples of the types of preservatives that may be used in the present invention include, for example, phenoxyethanol, sodium salicylate, methylparaben, butylparaben, propylparaben, diazolidinyl urea, sodium dehydroacetate, benzyl alcohol, sodium benzoate, iodide propynyl butylcarbamate, caprylyl glycol, disodium EDTA, or mixtures thereof. In particularly preferred embodiments, the preservative is sodium benzoate, phenoxyethanol, sodium salicylate, or a mixture thereof. The preservative is preferably used in an amount of 0.01 to 2% by weight of the hair care composition.

[0059] The hair care composition of the present invention may contain other components common in the art to enhance its physical properties and performance. Suitable components include, but are not limited to, fragrances, dyes and pigments, pH adjusters, pearlescent or opaque agents, viscosity modifiers, thickeners, and natural hair nutrients such as plant and fruit extracts, sugar derivatives and amino acids.

[0060] Method and Use The present invention also provides a method for depositing an anti-dandruff agent on the scalp, comprising the steps of applying a hair care composition described in any of the prior claims to the surface of an individual's scalp, and subsequently rinsing the surface with water. The anti-dandruff agent is selected from piroctone olamine, crimbazole, ketoconazole, selenium sulfide, and mixtures thereof. Piroctone olamine is preferred as the anti-dandruff agent. This method is essentially non-therapeutic. Preferably, it is for cosmetic purposes.

[0061] The present invention also provides the use of a combination of acrylamidopropyltrimonium chloride / acrylamide copolymer and cationic guar polymer to increase the deposition of an anti-dandruff agent on the scalp, the anti-dandruff agent being selected from piroctone olamine, crimbazole, ketoconazole, selenium sulfide, and mixtures thereof. The cationic guar polymer preferably has a molecular weight of 300,000 to 2,500,000 daltons and a degree of cationic substitution of 0.05 to 0.4. The anti-dandruff agent is preferably piroctone olamine. This use is essentially non-therapeutic and preferably essentially cosmetic.

[0062] Usage The compositions of the present invention are primarily intended for topical application to at least a portion of the scalp and / or hair of an individual, and are either rinse-off or leave-on compositions, preferably rinse-off compositions such as shampoos.

[0063] If the composition is a shampoo, the composition is applied topically to the hair and then massaged into the hair and scalp. Next, it is rinsed with water and the hair is dried.

[0064] The present invention is further illustrated by the following non-limiting embodiments, and unless otherwise specified, all percentages cited are based on total weight.

[0065] The examples are intended to illustrate the present invention and are not intended to limit the present invention to those examples themselves.

[0066] [Examples] [Example 1] This embodiment demonstrates that the combination of copolymer and cationic guar polymer can affect the deposition of anti-dandruff agents on the scalp. All components are expressed as active ingredient levels by weight percentage of the total formulation. [Table 1] method Approximately 0.2 grams of the test sample was collected on artificial skin (VITRO-SKIN from the IMS testing group). This was diluted with 1.8 mL of water and rubbed in with a plastic stick for 30 seconds. Then, the surface of the artificial skin was rinsed twice with water: first with 4 mL of water for 30 seconds, and then again with 4 mL of water for 30 seconds. (10.75 cm on the skin) 2 The deposition of piroctone olamine on the plate was measured using high-performance liquid chromatography (HPLC).

[0067] result The average deposition amounts (from five such experiments) are summarized in Table 2 (the error represents the standard deviation of the double measurements). [Table 2] Sample 1, which included a combination of copolymer and cationic guar polymer, showed significantly better (p<0.05) piroctone olamine deposition compared to Sample A (which contained only cationic guar polymer).

[0068] [Example 2] This example demonstrates that a desired sensory experience can be achieved through a combination of copolymers and cationic guar polymers. The compositions were prepared according to the formulations detailed in Table 3. All components are expressed as active ingredient levels by weight percentage of the total formulation. [Table 3] method This embodiment demonstrates, through sensory evaluation, that the performance of the shampoo according to the present invention has been improved.

[0069] In the beauty salon trial, the samples were tested on 36 female subjects. Before the trial, the subjects were assessed as having similar hair types (e.g., normal hair, dry hair, oily hair, etc.). For the given trial, 18 subjects with normal hair and 18 subjects with dry hair were selected. The evaluation was performed by trained beauticians with good sensitivity. The evaluation method was a paired comparison, in which half of the head was washed with sample B and the other half of the head was washed with sample 2.

[0070] result Hairdressers were asked to evaluate participants' hair against various standard attributes. The results showed that shampoo 2 was significantly higher (at least within a 95% confidence interval) in the following attributes.

[0071] Foam characteristics: - Foaming speed - Overall hair foaming - Abundance of foam The results show that sample 2, which contains both copolymer and cationic guar polymer, can improve the sensory experience, particularly the perception related to foaming / bubbling, compared to sample B, which contains only copolymer.

[0072] [Example 3] This example demonstrated that the ratio of copolymer to cationic guar polymer can affect the deposition of anti-dandruff agents on the scalp. The compositions were prepared according to the formulations detailed in Table 4. All components are expressed as active ingredient levels by weight percentage of the total formulation. [Table 4] method The same deposition evaluation method as disclosed in Example 1 was used.

[0073] result The average deposition amounts (from five such experiments) are summarized in Table 5. [Table 5] Samples 3 and 4, which contained copolymers and cationic guar polymers having ratios within the scope of the present invention, showed better deposition of piroctone olamine compared to sample C (which had ratios outside the scope of the present invention).

[0074] [Example 4] This example demonstrates that the ratio of copolymer to cationic guar polymer can affect the perceptual experience during application. The compositions were prepared according to the formulations detailed in Table 6. All components are expressed as active ingredient levels by weight percentage of the total formulation. [Table 6] method The performance disclosed in Example 2 was evaluated using sensory evaluation.

[0075] result Hairdressers were asked to evaluate participants' hair against various standard attributes. The results showed that shampoo 5 was significantly higher (with a 99% confidence interval) in the following attributes.

[0076] Foam characteristics: - Foaming speed - Overall hair foaming - Abundance of foam The results show that sample 5, which contains a copolymer and a cationic guar polymer having a ratio within the scope of the present invention, can improve the sensory experience, particularly the perception related to foaming / bubbling, compared to sample D, which has a weight ratio of copolymer and cationic guar polymer outside the scope of the present invention.

Claims

1. A hair care composition, a) A dandruff inhibitor selected from piroctone olamine, crimbazole, ketoconazole, selenium sulfide, and mixtures thereof, b) A copolymer containing acrylamidopropyltrimonium chloride, c) A cationic guar polymer having a molecular weight of 300,000 to 2,500,000 daltons and a degree of cationic substitution of 0.05 to 0.4, A hair care composition in which the weight ratio of the amount of the copolymer to the amount of the cationic guar polymer is in the range of 1:10 to 10:

1.

2. The composition according to claim 1, wherein the anti-dandruff agent is piroctone olamine.

3. The composition according to claim 1 or 2, wherein the copolymer is acrylamidopropyltrimonium chloride / acrylamide copolymer.

4. The composition according to any one of claims 1 to 3, wherein the cationic guar polymer has a molecular weight of 1,000,000 to 2,300,000 daltons.

5. The composition according to any one of claims 1 to 4, wherein the cationic guar polymer has a degree of cationic substitution of 0.1 to 0.

3.

6. The composition according to any one of claims 1 to 5, wherein the cationic guar polymer is guar hydroxypropyltrimonium chloride.

7. The composition according to any one of claims 1 to 6, wherein the composition comprises the copolymer in an amount of 0.001 to 2% by weight of the composition.

8. The composition according to any one of claims 1 to 6, wherein the composition comprises the copolymer in an amount of 0.01 to 1% by weight of the composition.

9. The composition according to any one of claims 1 to 8, wherein the composition contains the anti-dandruff agent in an amount of 0.01 to 10% by weight of the composition.

10. The composition according to any one of claims 1 to 8, wherein the composition contains the anti-dandruff agent in an amount of 0.01 to 5% by weight of the composition.

11. The composition according to any one of claims 1 to 10, wherein the composition comprises the cationic guar polymer in an amount of 0.01 to 2% by weight of the composition.

12. The composition according to any one of claims 1 to 10, wherein the composition comprises the cationic guar polymer in an amount of 0.04 to 2% by weight of the composition.

13. The composition according to any one of claims 1 to 12, wherein the weight ratio of the amount of the copolymer to the amount of the cationic guar polymer is in the range of 1:5 to 5:

1.

14. The composition according to any one of claims 1 to 12, wherein the weight ratio of the amount of the copolymer to the amount of the cationic guar polymer is in the range of 1:3 to 3:

1.

15. The composition according to any one of claims 1 to 14, wherein the composition comprises a cleaning surfactant.

16. The composition according to claim 15, wherein the cleaning surfactant is sodium lauryl ether sulfate.

17. The composition according to any one of claims 1 to 16, wherein the composition comprises a conditioning agent.

18. The composition according to claim 17, wherein the conditioning agent is a silicone oil.

19. The composition according to claim 17, wherein the conditioning agent is dimethicone, dimethiconol, or a mixture thereof.

20. A shampoo, the composition according to any one of claims 1 to 19.

21. A non-therapeutic method for depositing an anti-dandruff agent on the scalp, comprising the steps of applying a hair care composition according to any one of claims 1 to 20 to the surface of the scalp of an individual, and subsequently rinsing the surface with water.

22. Non-therapeutic use of a combination of acrylamidopropyltrimonium chloride / acrylamide copolymer and cationic guar polymer for increasing the deposition of an anti-dandruff agent on the scalp, wherein the anti-dandruff agent is selected from piroctone olamine, crimbazole, ketoconazole, selenium sulfide and mixtures thereof.

Images