Cosmetic composition comprising ferulic acid as active ingredient

Abstract

The present invention relates to a cosmetic composition containing ferulic acid, a basic amino acid, and a pH adjuster, which can suppress the decarboxylation decomposition reaction of ferulic acid, maintain the titer of ferulic acid even after long-term storage, prevent precipitation, discoloration, and reduction in efficacy, and provide a composition having excellent dosage form stability.

Description

Technical Field

[0001] The present invention relates to a cosmetic composition containing ferulic acid as an active ingredient, and specifically to a cosmetic composition containing ferulic acid, a basic amino acid, and a pH adjuster.

Background Art

[0002] Ferulic acid exhibits a broad antibacterial activity, is efficient in neutralizing reactive oxygen species, and can exhibit various effects as a topical skin agent such as antioxidant, UV protection, and skin whitening effects. Therefore, efforts have continued to develop cosmetics containing ferulic acid.

[0003] However, ferulic acid has very low solubility and low stability, so it could only be used restrictively in cosmetics. Specifically, since the pKa of ferulic acid is 4.61, there is a concern about precipitation at pH 5 or lower, and at pH 5 or higher, ferulic acid is decomposed by the decarboxylation reaction of ferulic acid, resulting in discoloration of the dosage form, reduction in titer, and reduction in the efficacy of ferulic acid.

[0004] Therefore, in order to solve the problem of precipitation of ferulic acid at pH 5 or lower, attempts have been made to add glycols and non-volatile polyols together with ferulic acid to improve solubility and storage stability. However, the content of glycols had to increase in accordance with the content of ferulic acid contained, and when glycols were used in excess, there was a concern about irritation to the skin.

[0005] Also, the pH of human skin is 5.5 - 6, but the pKa of ferulic acid is lower than this, and there was also a concern about skin irritation due to this. Therefore, from the perspective of human body safety, there was a need to develop a product that has a pH similar to that of the skin or similar to that of ordinary cosmetics while using a small amount of polyol.

[0006] At pH 5 or higher, the solubility of ferulic acid improves, reducing the amount of polyols needed and minimizing concerns about skin irritation. However, at pH 5 or higher, a decarboxylation reaction of ferulic acid occurs, causing rapid discoloration, decreased potency, and reduced efficacy of the composition, which can pose problems for cosmetic distribution.

[0007] Furthermore, conventional attempts have been made to improve the dosage form stability of ferulic acid by derivatizing it. However, while these derivatives improve dosage form stability, they do not exhibit the same skin-improving effects as ferulic acid. Therefore, instead of derivatizing ferulic acid, a strategy was needed to ensure that ferulic acid itself could be stably included in a certain content or higher. [Overview of the Initiative] [Problems that the invention aims to solve]

[0008] Against the aforementioned background, the present inventors conducted research to improve the stability of ferulic acid and, as a result, confirmed that using a basic amino acid and a pH adjuster in combination with ferulic acid prevents precipitation of ferulic acid, suppresses the decarboxylation reaction of ferulic acid, and prevents discoloration, decrease in potency, and decrease in efficacy of the composition, thereby completing the present invention.

[0009] Therefore, the present invention aims to provide a cosmetic composition that prevents discoloration, precipitation, decrease in potency and efficacy of a composition containing ferulic acid, and has excellent dosage form stability. [Means for solving the problem]

[0010] The present invention provides a cosmetic composition comprising ferulic acid; a basic amino acid; and a pH adjuster, wherein the ferulic acid content is 0.1% by weight or more relative to the total weight of the composition, and the pH is 4.0 to 6.0.

[0011] Furthermore, the present invention aims to provide a topical skin preparation containing the above-mentioned composition. [Effects of the Invention]

[0012] The present invention suppresses the decarboxylation reaction of ferulic acid, thereby maintaining the potency of ferulic acid even after long-term storage, preventing discoloration and loss of efficacy, and thus providing a composition with excellent dosage form stability.

[0013] Furthermore, this simultaneously improves the solubility of ferulic acid, reducing concerns about precipitation and preventing skin irritation. [Brief explanation of the drawing]

[0014] [Figure 1] This figure shows a photograph of the appearance of the composition according to Experimental Example 1. [Figure 2] This figure shows a photograph of the appearance of the composition in Example 3 after four weeks, as shown in Experimental Example 5. [Figure 3] This figure shows photographs of the appearance of Example 6 and Comparative Example 19 after storage at 25 degrees Celsius for 6 months, as shown in Experimental Example 6. [Modes for carrying out the invention]

[0015] The present invention will be described in detail below. However, since the present invention can be modified in various ways and may take various forms, the specific examples and descriptions described below are merely for the purpose of aiding the understanding of the invention and do not limit the invention to any particular form of disclosure. The scope of the present invention should be understood to include all modifications, equivalents, or substitutions that fall within the spirit and technical scope of the invention.

[0016] The "ferulic acid (4-hydroxy-3-methoxycinnamic acid)" of the present invention is a phenol compound, and its structure is as shown in Chemical Formula 1 below. Ferulic acid can exhibit antioxidant, antibacterial, skin whitening, UV protection, skin elasticity, and anti-aging effects.

[0017] [Chemistry]

[0018] Ferulic acid has very low solubility in water and is easily oxidized, so it is used restrictively in cosmetics. Thus, the present invention attempts to provide a cosmetic composition with improved dosage form stability of such ferulic acid.

[0019] The decomposition of ferulic acid begins by a decarboxylation reaction, which is accelerated at pH 5 or higher. The decarboxylation reaction of ferulic acid is shown in Reaction Formula 1 below.

[0020] [Chemistry]

[0021] The decarboxylation decomposition reaction of ferulic acid proceeds while the carboxyl functional group of ferulic acid, which is negatively charged in an aqueous solution, forms an ion pair with other positive charges. If such charge interactions can be suppressed, it is expected that the decomposition of ferulic acid can be suppressed, and thus measures were taken to increase the energy required for the decarboxylation decomposition reaction. Considering sodium or potassium ions as the above positive charges, these were not sufficient to improve the stability of ferulic acid because they were ionized well in an aqueous solution state and had low binding energy. After countless attempts, the inventors of the present invention confirmed that the stability of ferulic acid was improved when a basic amino acid was used as the cationic component, and thus the present invention was completed.

[0022] Therefore, the present invention provides a cosmetic composition containing ferulic acid; a basic amino acid; and a pH adjuster.

[0023] In one embodiment of the present invention, the content of ferulic acid may be 0.1% by weight or more relative to the weight of the total composition. Specifically, it may be 0.1 to 10% by weight, more specifically, 0.2% by weight or more, 0.3% by weight or more, 0.5% by weight or more, 0.8% by weight or more, 1% by weight or more, or 2% by weight or more, and may be 8% by weight or less, 7% by weight or less, 6% by weight or less, or 5% by weight or less.

[0024] In one embodiment of the present invention, the basic amino acid may be any basic amino acid known to those skilled in the art, preferably one or more selected from the group consisting of arginine, lysine, histidine, and carnitine, or their acids or bases, organic or mineral salts, most preferably carnitine or arginine. Basic amino acids are harmless to the human body and do not pose a concern for skin irritation even when used in large quantities, and can also improve the dosage form stability of ferulic acid. In particular, in addition to basic amino acids, the use of other components having an amine group, such as triethanolamine (TEA) and tromethamine (TRIS), can be considered for the same purpose, but basic amino acids are more preferred because triethanolamine and tromethamine pose a risk due to unreacted amines (in the case of TEA, N-nitrosodiethanolamine (NDELA), and in the case of TRIS, a secondary amine), and even if such unreacted products are not present at dangerous levels, there may still be a problem of skin irritation.

[0025] The content of the basic amino acid may vary depending on the content of ferulic acid and the pH adjuster and the pH of the composition, and is not limited as long as it is included together with ferulic acid and the pH adjuster to reach the pH range of the present invention.

[0026] In one embodiment of the present invention, the content of the basic amino acid may be 0.001 to 10% by weight relative to the weight of the total composition. Preferably, it may be 0.001 to 5% by weight, 0.01 to 3% by weight, or 0.01 to 1% by weight. When the basic amino acid is used within the above content range, the decarboxylation reaction of ferulic acid can be sufficiently suppressed, but when used in excess, there is a problem that it may induce skin irritation.

[0027] The pH of the composition may be 4.0 to 6.0. More specifically, the pH may be 4.4 to 6.0, 4.4 to 5.7, more preferably 4.4 to 5.5, 4.4 to 5.3, or 4.4 to 5.2. Such a pH can be adjusted with a pH adjuster. While increasing the pH improves the solubility of ferulic acid and reduces concerns about precipitation, it may accelerate the decomposition and titer reduction of ferulic acid, so the pH should be adjusted within an appropriate range.

[0028] The aforementioned pH adjusting agent is a component used to minimize changes in pH and maintain it within a certain range through conjugate base / conjugate acid action, rather than simply increasing or decreasing pH like strong acids and strong bases, and may also be a pH buffering agent.

[0029] Specifically, the pH adjusting agent may be one or more selected from the group consisting of sodium citrate, potassium citrate, magnesium citrate, salicylic acid, glutamic acid, sodium phosphate, disodium phosphate, potassium phosphate, dipotassium phosphate, calcium phosphate, lactic acid, sulfuric acid, succinic acid, sodium lactate, potassium lactate, calcium lactate, and magnesium lactate. Most preferably, it may be sodium citrate.

[0030] pH adjusters not only play a role in adjusting the pH of the composition, but their functional groups, such as carboxyl groups, hydroxyl groups, or amine groups, interact with ferulic acid (e.g., through hydrogen bonding or van der Waals forces), and can suppress the decarboxylation reaction of ferulic acid, similar to basic amino acids.

[0031] Furthermore, the pH adjusting agent may further contain EDTA.

[0032] The content of the pH adjusting agent may vary depending on the content of ferulic acid and basic amino acids and the pH range of the composition, and is not limited as long as it is included together with ferulic acid and basic amino acids to reach the pH of the present invention.

[0033] In one embodiment of the present invention, the content of the pH adjuster may be 0.001 to 3% by weight relative to the weight of the total composition. More specifically, it may be 0.01 to 3% by weight, 0.1 to 2% by weight, or 0.15 to 1.5% by weight. If the pH adjuster is present in a lower amount than the above, it may not be possible to prevent the rise in pH due to the decomposition of ferulic acid, and may accelerate the decomposition and decrease in potency of ferulic acid. If the content is higher than the above, it may affect the quality of the product.

[0034] In this invention, both the pH adjuster and the basic amino acid can act as pH buffers, reducing the impact of external changes on ferulic acid compared to when only one substance is used.

[0035] In one embodiment of the present invention, the weight ratio of ferulic acid, basic amino acid, and pH adjuster may be 1:0.1 to 1.5:0.1 to 1.

[0036] The composition of the present invention may further contain water and / or a polyol.

[0037] In one embodiment of the present invention, in order to avoid stickiness or a heavy feeling, the polyol content may be 20% by weight or less, or 17.5% by weight or less, relative to the total weight of the composition. Preferably, it may be 1 to 20% by weight, or 2 to 18% by weight, or 5 to 17.5% by weight.

[0038] The polyol may contain one or more of glycerin and glycols, and the glycols may be one or more selected from the group consisting of dipropylene glycol, butylene glycol, propanediol, ethoxydiglycol, 2,3-butanediol, and 1,2-hexanediol. Preferably, considering solubility, the polyol may be propanediol and / or ethoxydiglycol.

[0039] The polyol can act as a humectant and can be used in sufficient quantities to stabilize ferulic acid within the dosage form; otherwise, precipitation of ferulic acid may occur. In the present invention, the amount of polyol can be used in amounts of approximately 0.01 to 50 times, 0.05 to 30 times, 0.1 to 20 times, or 3 to 20 times the amount of ferulic acid. If the polyol content is too high, skin irritation may occur.

[0040] In one embodiment of the present invention, the water content may be 50% by weight or more. More specifically, it may be 50 to 90% by weight, and more specifically, 50 to 80% by weight, or 60 to 80% by weight.

[0041] In one embodiment of the present invention, the cosmetic composition of the present invention may not discolor or precipitate, or maintain its potency, even when stored at 50 degrees Celsius for four weeks.

[0042] In the present invention, "potency maintenance" means that ferulic acid is hardly decomposed even when stored at 50 degrees Celsius for 4 weeks. Specifically, the degree of ferulic acid decomposition may be 10% or less, 5% or less, or not decomposed at all.

[0043] The present invention also provides a topical skin preparation comprising the aforementioned cosmetic composition.

[0044] The components included in the cosmetic composition of the present invention may include, in addition to the active ingredient, components commonly used in cosmetic compositions, such as antioxidants, stabilizers, solubilizers, vitamins, UV absorbers, preservatives, pH adjusters, dyes, pigments and fragrances, and other common auxiliary agents, as well as carriers.

[0045] The cosmetic composition of the present invention can be manufactured in any dosage form commonly produced in the industry, such as, but is not limited to, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, cleansing oils, powder foundations, emulsion foundations, wax foundations, packs, massage creams, and sprays. More specifically, it can be manufactured in the form of lotions, emulsions, softening lotions, nourishing lotions, nourishing creams, massage creams, essences, eye creams, cleansing creams, cleansing foams, cleansing waters, packs, sprays, or powders.

[0046] Each of the components described above that are included in the cosmetic composition according to the present invention may preferably be included in the cosmetic composition according to the present invention in a manner that does not exceed the maximum amount of use specified in the regulations related to "cosmetic use and authorization" established by each national government.

[0047] In another embodiment, the present invention provides a method for producing a cosmetic composition containing ferulic acid, comprising the step of mixing ferulic acid with a basic amino acid and a pH adjuster to produce a cosmetic composition having a pH of 4.0 to 6.0.

[0048] In the above manufacturing method, the ferulic acid content may be 0.1% by weight or more relative to the total weight of the composition.

[0049] In the above manufacturing method, polyol and / or water may be further mixed.

[0050] The above manufacturing method may further include a step of heating the mixture of the basic amino acid and pH adjuster to 40-70 degrees Celsius.

[0051] The above manufacturing method may be for producing a cosmetic composition in which ferulic acid does not substantially precipitate, discolor, and / or decrease in potency. Specifically, it may be for producing a cosmetic composition in which ferulic acid does not substantially precipitate, discolor, and / or decrease in potency even when stored at 50 degrees Celsius for 4 weeks.

[0052] In the above manufacturing method, ferulic acid, basic amino acids, pH adjusters, and cosmetic compositions can be applied as described above.

[0053] In another embodiment, the present invention provides basic amino acids and pH adjusters for the production of cosmetic compositions containing ferulic acid that are substantially free from precipitation, discoloration, and / or loss of potency of ferulic acid.

[0054] In the aforementioned applications, ferulic acid, basic amino acids, pH adjusters, and cosmetic compositions can be applied as described above.

[0055] In the present invention, "substantially absent" can mean that even after storage at 50 degrees Celsius for four weeks, precipitation, discoloration, and / or reduction in potency of ferulic acid do not occur, or the degree of decomposition of ferulic acid is 10% or less, or 5% or less.

[0056] The present invention will be described in detail below with reference to the following experimental examples. However, the following experimental examples are merely illustrative of the present invention, and the content of the present invention is not limited by these examples. Furthermore, these experimental examples are for the sole purpose of aiding understanding of the present invention, and therefore, in no sense are the scope of the present invention limited by them. [Examples]

[0057] In this example, the stability of ferulic acid was confirmed based on pH (Experimental Example 1), the stability of ferulic acid due to the cationic component used to stabilize it (Experimental Example 2), the type of amino acid (Experimental Example 3), and the content of the pH adjuster (Experimental Example 4). As a result, compositions according to the present invention were prepared as shown in Experimental Examples 5 and 6, and dosage form stability and potency analysis were performed.

[0058] <Dosage Form Stability Evaluation> The stability of the dosage forms was confirmed for the compositions produced in each of the experiments described below. Specifically, the compositions produced in each experiment were stored for 4 weeks at 25°C, 50°C, and -15°C, or stored for 8 hours under exposure conditions (sunlight), and then evaluated for discoloration and precipitation according to the following criteria. 1. Discoloration O: No color change, or difficult to perceive. △: The color change is perceptible, but not to the extent that it affects preference. X: The color change is so bad that it negatively impacts the taste. 2. Precipitation O: No precipitation X: Precipitation is observed.

[0059] Experimental Example 1. Observation of the pH stability of ferulic acid. According to the compositions shown in Table 1 below, the mixtures were heated and mixed at 50°C, and then cooled to produce the compositions of Comparative Examples 1 to 5, which have the following compositions.

[0060] [Table 1]

[0061] The above-mentioned <Dosage Form Stability Evaluation> was performed on the compositions of Comparative Examples 1 to 5 that were manufactured, and the results are shown in Tables 2 and 3.

[0062] [Table 2]

[0063] [Table 3]

[0064] Table 3 shows that precipitation occurs under freezing conditions when the pH is low (Comparative Examples 1 and 2), and Table 2 shows that discoloration occurs when exposed to high temperatures or light when the pH is high (Comparative Examples 2-5). In other words, it was confirmed that the decomposition of ferulic acid accelerates over time when the pH is 4 or higher, and that it is necessary to suppress the decomposition of ferulic acid.

[0065] Experimental Example 2. Observation of the stability of ferulic acid due to cationic components. According to the compositions shown in Table 4 below, the mixtures were heated and mixed at 50°C, then cooled to produce the compositions of Comparative Examples 6 to 9, which have the following compositions. Arginine, tromethamine, NaOH, and KOH were added in appropriate amounts to adjust the pH to 5.

[0066] [Table 4]

[0067] The above-mentioned <Dosage Form Stability Evaluation> was performed on the compositions of Comparative Examples 6 to 9 that were manufactured, and the results are shown in Tables 5 and 6.

[0068] [Table 5]

[0069] [Table 6]

[0070] As shown in Tables 5 and 6 above, no significant difference in the stability of ferulic acid was observed in Comparative Examples 6 to 9. However, slight discoloration was confirmed at high temperatures (50 degrees Celsius for 4 weeks). Furthermore, similar to Comparative Example 3, no precipitation was confirmed in all of Comparative Examples 6 to 9 under freezing conditions at pH 5. Therefore, it was confirmed that basic amino acids can be used as components to stabilize ferulic acid instead of other potentially hazardous components such as tromethamine and strong bases such as KOH and NaOH.

[0071] Experimental Example 3. Observation of the stability of ferulic acid depending on the type of amino acid. According to the compositions shown in Table 7 below, the mixtures were heated and mixed at 50°C, and then cooled to produce the compositions of Comparative Examples 10 to 13, which have the following compositions.

[0072] [Table 7]

[0073] The above-mentioned <Dosage Form Stability Evaluation> was performed on the compositions of Comparative Examples 10 to 13 that were manufactured, and the results are shown in Tables 8 and 9.

[0074] [Table 8]

[0075] [Table 9]

[0076] As shown in Tables 8 and 9 above, Comparative Examples 10 and 11, which used arginine and carnitine, respectively, among the basic amino acids, were confirmed to have excellent dosage form stability. In Comparative Example 12, which used aspartic acid, one of the acidic amino acids, the contribution of ferulic acid to stabilization could not be confirmed because it did not dissolve during the manufacturing process. In Comparative Example 13, which used serine, one of the neutral amino acids, the pH could not be raised above 4 even when an excess amount was added, resulting in the problem of precipitation.

[0077] Experimental Example 4. Observation of Stability Based on pH Adjuster Content According to the compositions shown in Table 10 below, the mixtures were heated and mixed at 50°C, and then cooled to produce the compositions of Comparative Examples 14 to 18, which have the following compositions.

[0078] [Table 10]

[0079] The above-mentioned <Dosage Form Stability Evaluation> was performed on the compositions of Comparative Examples 14 to 18 that were manufactured, and the results are shown in Tables 11 and 12.

[0080] [Table 11]

[0081] [Table 12]

[0082] Comparative Examples 14 and 15, which contained 0.1% and 0.2% by weight of sodium citrate and had pH values ​​of 4.3 and 4.6, respectively, showed ferulic acid precipitation under freezing conditions. However, Comparative Examples 16-18, which contained 0.5%, 0.8%, and 1.0% by weight of sodium citrate and had pH values ​​adjusted to 5.2-5.7, were confirmed to be stable under freezing conditions. However, Comparative Examples 16-18 had the problem of partial discoloration under exposure conditions.

[0083] Experimental Example 5. Observation of the stability of the composition according to the present invention. According to the compositions in Table 13 below, the mixtures were heated and mixed at 50°C, then cooled to produce the compositions of Examples 1 to 5 having the following compositions.

[0084] [Table 13]

[0085] The above-mentioned <Dosage Form Stability Evaluation> was performed on the compositions of Examples 1 to 5 that were manufactured, and the results are shown in Tables 14 and 15.

[0086] [Table 14]

[0087] [Table 15]

[0088] Based on the results obtained from Experimental Examples 1-4 regarding amine components and pH adjusters, the composition of this embodiment was manufactured. Although slight differences in stability were observed depending on the pH, it was confirmed that the composition exhibited excellent overall dosage form stability.

[0089] Experimental Example 6. Observation of the stability of emulsion formulations. According to Table 16 below, the aqueous phase (raw materials 1-9) was mixed and heated to 50°C, and the polymer phase (raw materials 10-12) was mixed and maintained at 50°C. The oil phase (raw materials 13 and 14) was also mixed and heated to 50°C. The aqueous and polymer phases were mixed using a homomixer at 5000 rpm for 5 minutes, after which the oil phase was added and stirred further at 5000 rpm for 5 minutes. The mixture was then cooled to 30°C.

[0090] [Table 16] * ABIL CARE XL 80: Bis-PEG / PPG-20 / 5PEG / PPG-20 / 5 Dimethicone, MethoxyPEG / PPG-25 / 4 Dimethicone

[0091] The compositions of Example 6 and Comparative Example 19, which were manufactured, were subjected to the same method as described in the <Dosage Form Stability Evaluation>, but the evaluation at temperatures of 25°C, 50°C, and -15°C was performed by checking for discoloration after storage for 6 months, and the results are shown in Table 17.

[0092] [Table 17]

[0093] We were able to confirm that the composition of Example 6 had superior dosage form stability compared to Comparative Example 19. In particular, as shown in Figure 3, a clear difference in color was observed after storage at 25°C for 6 months, which can directly relate to product quality.

[0094] Experimental Example 7. Potency analysis of ferulic acid at different pH levels. When Comparative Examples 1, 3, and 5, prepared in Experimental Example 1, and Example 3, prepared in Experimental Example 5, were stored at 50°C for 4 weeks, the extent to which ferulic acid decreased was confirmed. Specifically, the amount of ferulic acid at the time of measurement was quantified relative to the initial ferulic acid content, and the extent to which ferulic acid decreased was evaluated. The initial ferulic acid content for Comparative Examples 1, 3, and 5 was 0.3% by weight, and for Example 3 it was 0.5% by weight.

[0095] [Table 18]

[0096] Comparative Examples 1, 3, and 5 demonstrate that when stored at 50°C for 4 weeks, ferulic acid decomposition occurs, and the decrease in potency becomes more pronounced as the pH increases.

[0097] Furthermore, although Example 3 had the same pH of 5 as Comparative Example 3, the ferulic acid content was 0.50% by weight, and since the ferulic acid was hardly decomposed, it was confirmed that the potency was not reduced at high temperatures and was stably maintained.

[0098] The degree of ferulic acid reduction was also confirmed for Example 6 and Comparative Example 19, which are emulsion formulations prepared in Experimental Example 6, and the results are shown in Table 19 below.

[0099] [Table 19]

[0100] As a result of checking the amount of ferulic acid remaining after high temperature and time, it was confirmed that the ferulic acid in Example 6 remained stable without decomposition, while decomposition of ferulic acid occurred in Comparative Example 19.

Claims

1. It contains ferulic acid, carnitine, a pH adjuster, and one or more polyols. The content of ferulic acid is 0.1% by weight or more relative to the total weight of the composition. It has a pH of 4.0 to 6.

0. A cosmetic composition wherein the content of the polyol is 0.01 to 50 times the content of ferulic acid.

2. The cosmetic composition according to claim 1, wherein the carnitine content is 0.001 to 10% by weight relative to the weight of the whole composition.

3. The cosmetic composition according to claim 1, wherein the pH adjusting agent is one or more selected from the group consisting of sodium citrate, potassium citrate, magnesium citrate, salicylic acid, glutamic acid, sodium phosphate, disodium phosphate, potassium phosphate, dipotassium phosphate, calcium phosphate, lactic acid, sulfuric acid, succinic acid, sodium lactate, potassium lactate, calcium lactate, and magnesium lactate.

4. The cosmetic composition according to claim 1, wherein the content of the pH adjuster is 0.001 to 3% by weight relative to the weight of the whole composition.

5. The cosmetic composition according to claim 1, wherein the polyol is one or more selected from the group consisting of glycerin, dipropylene glycol, butylene glycol, propanediol, ethoxydiglycol, 2,3-butanediol, and 1,2-hexanediol.

6. The cosmetic composition according to claim 1, comprising 50% by weight or more of water relative to the weight of the overall composition.

7. The cosmetic composition according to claim 1, characterized in that it does not discolor or precipitate, or maintains its potency, even when stored at 50 degrees Celsius for four weeks.

8. A topical skin preparation comprising a cosmetic composition according to any one of claims 1 to 7.

9. The process includes the step of mixing ferulic acid with carnitine, a pH adjuster, and one or more polyols to produce a cosmetic composition with a pH of 4.0 to 6.

0. A method for producing a cosmetic composition containing ferulic acid, The content of ferulic acid is 0.1% by weight or more relative to the total weight of the composition. A method for producing the polyol, wherein the content of the polyol is 0.01 to 50 times the content of ferulic acid.

10. The method for producing a cosmetic composition containing ferulic acid according to claim 9, wherein the production method is for producing a cosmetic composition in which there is substantially no precipitation, discoloration, and / or decrease in potency of ferulic acid.

Images