Stabilized formutations.containing anti-pcsk9 antibodies
PK201200498A0Active Publication Date: 2012-09-05REGENERON PHARMACEUTICALS INC
Patent Information
- Authority / Receiving Office
- PK · PK
- Patent Type
- Applications
- Current Assignee / Owner
- REGENERON PHARMACEUTICALS INC
- Filing Date
- 2012-07-26
- Publication Date
- 2012-09-05
Abstract
The present invention provides pharmaceutical formulation comprising a human antibody that specifically binds to human proprotein convertase subtilisin / kexin type 9 (PCSK9). The formulation may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulation o f the present invention exhibits a substantial degree o f antibody stability after storage for several months.
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