Herbicidal composition

Abstract

The present invention relates to a herbicidal composition. The present invention further relates to a suspension concentrate comprising at least one herbicide selected from the group comprising acetolactate synthase (ALS) inhibitor herbicides and at least one herbicide selected from the group comprising photosynthesis inhibitor herbicide at PS II system.

Description

[0001] HERBICIDAL COMPOSITION

[0002] Technical field

[0003] The present invention relates to a herbicidal composition. The present invention further relates to a suspension concentrate.

[0004] Background

[0005] Use of multiple crop protection pesticides is often mandated for control of a variety of pests, new herbicide combinations must be tested for interactions due to the variability among herbicides within a family and among weed species. A common practice in crop protection is tank mixing pesticides and other agrochemicals such as adjuvants, fertilizers, bio-stimulants, and plant growth regulators.

[0006] Propanil [N-(3,4-Dichlorophenyl)propanamide] is a chlorinated anilide that is used as a herbicide for the control of numerous grasses and broad-leaved weeds in rice, potatoes, and wheat crop. Propanil is a post-emergence herbicide. It is moderately soluble in water and has a low volatility.

[0007] Penoxsulam is a triazolopyrimidine sulfonamide and belongs to the ALS (acetolactate synthase) inhibitor herbicide group intended for postemergence application for selective control of grass, broadleaf, and sedge weeds.

[0008] Several pesticidal compositions have been developed over time to destroy pests and alleviate the damages they cause. These compositions are often applied to the environment in which the insects or other pests live or where their eggs are present, including the air surrounding them, the food they eat, or objects which they contact. Several of these compositions are vulnerable to chemical and physical degradation when applied to these environments. If these types of degradation occur, the pesticidal activity can be adversely affected and eventually the compositions are not stable.

[0009] A suspension concentrate is produced by dispersing insoluble solid active ingredient particles in the aqueous continuous phase. SC’s have been rampantly used due to benefits such as absence of dust, ease of use and effectiveness when compared to formulation types such as emulsifiable concentrate (EC) and wettable powder (WP) formulations. To formulate a stable SC, the active ingredient must remain insoluble under varying temperature conditions.

[0010] The smaller the particle size of the active ingredient particles in a suspension concentrate relates to a shorter residual period, which enhances the biological efficacy of the SC. Utilizing smaller particle sizes in agrochemicals enhance their overall effectiveness and minimize their environmental impact. These advantages stem from the increased surface area of active ingredients, allowing for better contact with target pests, pathogens, weeds or plants. This improved contact potential translates into a heightened ability to control pests and diseases, contributing to more successful outcomes in crop protection. Reducing particle size also leads to improved dispersion and suspension of the active ingredients in liquid formulations. This is pivotal in preventing particle agglomeration and settling, ensuring a uniform chemical distribution when sprayed. The result is a more efficient and thorough coverage of the target areas, maximizing the chemicals’ impact while reducing waste and uneven application. Additionally, smaller particles are more bioavailable and are absorbed more easily by plants or organisms, allowing for potentially reduced required dosages while still achieving the desired results. Applying agricultural chemicals in lower quantities not only enhances safety but also minimizes the risk of over-application, reducing the chances of potential environmental contamination and harmful effects on non-target species.

[0011] The preparation of suspension concentrates that are physically stable remain a challenge, as temperature fluctuations, storage conditions and handling procedures can materially affect the solubility characteristics of relatively insoluble active ingredients that have been formulated into a suspension.

[0012] Suspension concentrates of herbicidal mixtures are known to have issues relating to the particle size of actives considering storage conditions, handling procedures and transporting, thereby hindering the ultimate end goal of the herbicidal composition, i.e. efficient control of weeds.

[0013] There is a need in the art to provide a stable suspension concentrate having consistent particle size, favorable viscosity and suspensibility of particles over varying storage conditions, thus making it conducive for efficient applications in agriculture. Summary of the invention

[0014] In an aspect, the present invention provides a herbicidal composition comprising; a) at least one herbicide selected from the group comprising acetolactate synthase (ALS) inhibitor herbicides, b) at least one herbicide selected from the group comprising photosynthesis inhibitor herbicide at PS II system, and c) agrochemically acceptable excipients.

[0015] In an aspect, the present invention provides a suspension concentrate (SC) comprising; a) at least one herbicide selected from the group comprising acetolactate synthase inhibitor herbicides, b) at least one herbicide selected from the group comprising photosynthesis inhibitor herbicide at PS II system, and c) agrochemically acceptable excipients.

[0016] In another aspect, the present invention provides a suspension concentrate comprising; a) at least one herbicide selected from the group comprising acetolactate synthase inhibitor herbicides, b) at least one herbicide selected from the group comprising photosynthesis inhibitor herbicide at PS II system, c) at least one viscosity modifier comprising polymer(s), d) at least one dispersant comprising anionic surfactant(s), and e) agrochemically acceptable excipients.

[0017] In yet another aspect, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) at least one viscosity modifier comprising polymer(s), d) at least one dispersant comprising anionic surfactant(s), and e) agrochemically acceptable excipients. In one aspect, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) a polymer selected from the group comprising polyvinylpyrrolidone, cellulosic polymer(s), d) an anionic surfactant selected from lignosulfonate, and e) agrochemically acceptable excipients.

[0018] In one aspect, the present invention provides a method for controlling weeds by applying at a locus of a weed a suspension concentrate comprising a) penoxsulam, b) propanil, c) a polymer selected from the group comprising polyvinylpyrrolidone, cellulosic polymer(s), d) an anionic surfactant selected from lignosulfonate, and e) agrochemically acceptable excipients.

[0019] In one more aspect, the present invention provides use of a suspension concentrate for controlling weeds, the said suspension concentrate comprising; a) penoxsulam, b) propanil, c) a polymer selected from the group comprising polyvinylpyrrolidone, cellulosic polymer(s), d) an anionic surfactant selected from lignosulfonate, and e) agrochemically acceptable excipients.

[0020] Detailed description of the invention

[0021] The present disclosure now will be described hereinafter with reference to the accompanying examples, in which embodiments of the disclosure are shown. This description is not intended to be a detailed catalogue of all the different ways in which the disclosure may be implemented, or all the features that may be added to the instant disclosure. For example, features illustrated with respect to one embodiment may be incorporated into other embodiments, and features illustrated with respect to a particular embodiment may be deleted from that embodiment. Thus, the disclosure contemplates that in some embodiments of the disclosure, any feature or combination of features set forth herein can be excluded or omitted. In addition, numerous variations and additions to the various embodiments suggested herein will be apparent to those skilled in the art in light of the instant disclosure, which do not depart from the instant disclosure. Hence, the following descriptions are intended to illustrate some particular embodiments of the disclosure, and not to exhaustively specify all permutations, combinations and variations thereof.

[0022] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the disclosure, suitable methods and materials are described herein.

[0023] “About” or “approximately” as used herein is inclusive of the stated value and means within an acceptable range of deviation for the particular value as determined by one of ordinary skill in the art, considering the measurement in question and the error associated with measurement of the particular quantity (i.e., the limitations of the measurement system). For example, “about” can mean within one or more standard deviations, or within ± 10% or ± 5% of the stated value.

[0024] Recitation of ranges of values are merely intended to serve as a shorthand method of referring individually to each separate value falling within the range, unless otherwise indicated herein, and each separate value is incorporated into the specification as if it were individually recited herein. The endpoints of all ranges are included within the range and independently combinable. As used herein, all numerical values or numerical ranges include integers within such ranges and fractions of the values or the integers within ranges unless the context clearly indicates otherwise. Thus, for example, reference to a range of 90-100%, includes 91%, 92%, 93%, 94%, 95%, 95%, 97%, etc., as well as 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc., and so forth. All methods described herein can be performed in a suitable order unless otherwise indicated herein or otherwise clearly contradicted by context.

[0025] The use of the terms “a”, “an” and “the” and similar referents (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The terms first, second etc., as used herein are not meant to denote any particular ordering, but simply for convenience to denote a plurality of, for example, layers.

[0026] The terms “comprising”, “having”, “including”, and “containing” are to be construed as open-ended terms (i.e., meaning “including, but not limited to”) unless otherwise noted. “About” or “approximately” as used herein is inclusive of the stated value and means within an acceptable range of deviation for the particular value as determined by one of ordinary skill in the art, considering the measurement in question and the error associated with measurement of the particular quantity (i.e., the limitations of the measurement system). For example, “about” can mean within one or more standard deviations, or within ±10% or ±5% of the stated value.

[0027] The use of any and all examples, or exemplary language (e.g., “such as”), is intended merely to better illustrate the disclosure and does not pose a limitation on the scope of the disclosure unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the disclosure as used herein.

[0028] While the disclosure has been described with reference to an exemplary embodiment, it will be understood by those skilled in the art that various changes may be made, and equivalents may be substituted for elements thereof without departing from the scope of the disclosure. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the disclosure without departing from the essential scope thereof. Therefore, it is intended that the disclosure is not limited to the particular embodiment disclosed as the best mode contemplated for carrying out this disclosure, but that the disclosure will include all embodiments falling within the scope of the appended claims. The expression of various quantities in terms of “%” or “% w / w” means the percentage by weight of the total solution or composition unless otherwise specified.

[0029] The term ‘herbicide’ as used herein denotes a compound which controls or modifies the growth of undesired weeds / plants.

[0030] The term ‘stable’ referred to herein refers to chemical and / or physical stabilization of the active ingredients in the composition and desired suspensibility and dispersibility of the composition by maintaining homogeneity of the components that impart longer shelf life.

[0031] The term AHS refer to Accelerated heat stability (AHS), wherein experimental studies are carried out to determine the stability of the composition after 14 days of preparing the said composition at a temperature of 54°C.

[0032] Particle size is typically defined as a log-normal distribution with a median diameter or d50- that is 50% of the particles measured are less than the median value and 50% are greater than the median value. The term "particle size distribution" as used herein refers to the relative percentages by weight or volume of each of the different size fractions of a particulate matter. The term "median particle size", "median diameter of particles", "d50", as used herein refers to the median or 50% quantile of a particle size distribution. The term "d50" hence defines a size where 50 volume percent of the particles have sizes less than the value given.

[0033] The terms “ambient temperature” and “room temperature” as utilized herein shall generally mean any suitable temperature found in a laboratory or other working quarter, and is generally not below about 15°C nor above about 30° C.

[0034] The physicochemical studies of the compositions / formulation is performed according to the CIPAC standard method.

[0035] The term ‘herbicidally effective amount’ indicates the quantity of such a compound or combination of such compounds which is capable of controlling or modifying effect on the growth of harmful plants / undesired vegetation / weeds. Controlling effects include all deviation from natural development, for example: killing, retardation, leaf burn, albinism, dwarfism, etc. The terms “plants” and “vegetation” include, but are not limited to, germinant seeds, emerging seedlings, plants emerging from vegetative propagules, and established vegetation.

[0036] The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

[0037] As used herein, the term ‘pre-emergence’ refers to the time point before seedlings emerge from the ground. When any herbicide is applied at the pre-emergence stage, it prevents establishment of the germinated weed seedlings.

[0038] As used herein, the term ‘post-emergence’ refers to the time point after seedlings emerge from the ground. When any herbicide is applied at post-emergence stage, it prevents growth of the germinated weed seedlings.

[0039] The terms "undesirable vegetation", "harmful plants", "unwanted plants", "weeds" and "weed species", as used herein, are synonyms.

[0040] The term “control” provides includes control of the weed, as well as protecting a plant, a portion of the plant, or a plant seed from attack or invasion by said weed.

[0041] The term “locus” as used herein shall denote the vicinity of a desired crop in which weed control, typically selective weed control is desired. The locus includes the vicinity of desired crop plants wherein the weed infestation has either emerged or is yet to emerge.

[0042] Each of the aspects described above may have one or more embodiments.

[0043] Each of the embodiments described hereinafter may apply to one or all of the aspects described hereinabove. These embodiments are intended to be read as being preferred features of one or all of the aspects described hereinabove. Each of the embodiments described hereinafter applies to each of the aspects described hereinabove individually.

[0044] The present invention provides a herbicidal suspension concentrate (SC) formulation comprising an acetolactate synthase (ALS) inhibitor herbicides and photosynthesis inhibitor herbicide. The present inventors have attempted to provide a smaller particle size of the active ingredient particles in the said SC which results in the enhanced biological efficacy of the SC. Utilizing smaller particle sizes in the present invention was shown to enhance their overall effectiveness and minimize their environmental impact. These advantages stem from the increased surface area of active ingredients, allowing for better contact with target pests, pathogens, weeds or plants. This improved contact potential translates into a heightened ability to control pests and diseases, contributing to more successful outcomes in crop protection.

[0045] In an embodiment, the present invention provides a herbicidal composition comprising; a) at least one herbicide selected from the group comprising acetolactate synthase (ALS) inhibitor herbicides, b) at least one herbicide selected from the group comprising photosynthesis inhibitor herbicide at PS II system, and c) agrochemically acceptable excipients.

[0046] In an embodiment, the present invention provides a suspension concentrate (SC) comprising; a) at least one herbicide selected from the group comprising acetolactate synthase (ALS) inhibitor herbicides, b) at least one herbicide selected from the group comprising photosynthesis inhibitor at PS II system, and c) agrochemically acceptable excipients.

[0047] In an embodiment, the present invention provides a suspension concentrate comprising; a) at least one herbicide selected from the group comprising acetolactate synthase (ALS) inhibitor herbicides comprising triazolopyrimidines, b) at least one herbicide selected from the group comprising photosynthesis inhibitor herbicides at PS II system comprising amides, c) at least one viscosity modifier selected from the group comprising polymer(s), d) at least one dispersant comprising anionic surfactant(s), and e) agrochemically acceptable excipients. In an embodiment, the present invention provides an acetolactate synthase (ALS) inhibitor herbicide selected from the group comprising triazolopyrimidines.

[0048] In an embodiment, the present invention provides triazolopyrimidines selected from the group comprising penoxsulam and pyroxsulam.

[0049] In an embodiment, the present invention provides triazolopyrimidines comprising penoxsulam.

[0050] In an embodiment, the present invention provides a photosynthesis inhibitor herbicide at PS II system comprising amides.

[0051] In an embodiment, the present invention provides amides comprising propanil and chloranocryl / dicry I.

[0052] In an embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) at least one viscosity modifier selected from the group comprising polymer(s), d) at least one dispersant comprising anionic surfactant(s), and e) agrochemically acceptable excipients.

[0053] In an embodiment, the anionic surfactant is a sulfonate type of surfactant, which is a lignosulfonate. The lignosulfonate may, for example, be calcium lignosulfonate, sodium lignosulfonate, sodium alkyl naphthalene sulphonate, sodium alkyl naphthalene sulphonate formaldehyde condensate, potassium lignosulfonate, magnesium lignosulfonate or ammonium lignosulfonate.

[0054] Other non-limiting examples of suitable anionic surfactants include any conventional anionic surfactant. This may include a sulfate detersive surfactant, for e.g., alkoxylated and / or non-alkoxylated alkyl sulfate materials, and / or sulfonic detersive surfactants, e.g., alkyl benzene sulfonates. Suitable anionic surfactants may be derived from renewable resources, waste, petroleum, or mixtures thereof. Suitable anionic surfactants may be linear, partially branched, branched, or mixtures thereof. In one embodiment, the viscosity modifiers or thickeners or rheology modifier suitable for use in the present invention include, but are not limited to, polyvinylpyrrolidone, cellulosic polymers, microcrystalline cellulose, microfibri Hated cellulose, hydroxy propyl methyl cellulose, hydroxyethyl cellulose, magnesium aluminum silicate, attapulgite clay, hydrophilic fumed silica, aluminum oxide, xanthan gum or mixtures thereof

[0055] In another embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) a polymer selected from the group comprising polyvinylpyrrolidone and cellulosic polymers, d) an anionic surfactant selected from lignosulfonates, and e) agrochemically acceptable excipients.

[0056] In a preferred embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) microcrystalline cellulose, d) lignosulfonate, and e) agrochemically acceptable excipients.

[0057] In another preferred embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) microfibri Hated cellulose, d) lignosulfonate, and e) agrochemically acceptable excipients. In another preferred embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) polyvinylpyrrolidone and microcrystalline cellulose, d) lignosulfonate, and e) agrochemically acceptable excipients.

[0058] In another preferred embodiment, the present invention provides a suspension concentrate comprising; a) penoxsulam, b) propanil, c) polyvinylpyrrolidone and microfibri Hated cellulose, d) lignosulfonate, and e) agrochemically acceptable excipients.

[0059] In an embodiment, the present invention provides an ALS inhibitor herbicide in a concentration ranging from 0.5% w / w to 2% w / w of the composition.

[0060] In an embodiment, the present invention provides triazolopyrimidines in a concentration ranging from 0.5% w / w to 2% w / w of the composition.

[0061] In an embodiment, the present invention provides penoxsulam in a concentration ranging from 0.5% w / w to 2% w / w of the composition.

[0062] In an embodiment, the present invention provides penoxsulam in a concentration of 1% w / w of the composition.

[0063] In an embodiment, the present invention provides penoxsulam in a concentration of 0.94 % w / w of the composition.

[0064] In an embodiment, the present invention provides pyroxsulam in a concentration ranging from 0.5% w / w to 2% w / w of the composition.

[0065] In an embodiment, the present invention provides pyroxsulam in a concentration of 1% w / w of the composition. In an embodiment, the present invention provides photosynthesis inhibitor herbicide in a concentration ranging from 1% w / w to 50% w / w of the composition.

[0066] In an embodiment, the present invention provides photosynthesis inhibitor herbicide in a concentration ranging from 10% w / w to 40% w / w of the composition.

[0067] In an embodiment, the present invention provides a photosynthesis inhibitor herbicide in a concentration ranging from 20% w / w to 40% w / w of the composition.

[0068] In an embodiment, the present invention provides a photosynthesis inhibitor herbicide in a concentration of 36% w / w of the composition.

[0069] In an embodiment, the present invention provides amides in a concentration ranging from 1% w / w to 50% w / w of the composition.

[0070] In an embodiment, the present invention provides amides in a concentration ranging from 10% w / w to 40% w / w of the composition.

[0071] In an embodiment, the present invention provides amides in a concentration ranging from 20% w / w to 40% w / w of the composition.

[0072] In an embodiment, the present invention provides amides in a concentration of 36% w / w of the composition.

[0073] In an embodiment, the present invention provides propanil in a concentration ranging from 1% w / w to 50% w / w of the composition.

[0074] In an embodiment, the present invention provides propanil in a concentration ranging from 10% w / w to 40% w / w of the composition.

[0075] In an embodiment, the present invention provides propanil in a concentration ranging from 20% w / w to 40% w / w of the composition.

[0076] In an embodiment, the present invention provides propanil in a concentration of 36% w / w of the composition.

[0077] In an embodiment, the ratio of the viscosity modifier and dispersant is ranging from 1:20 to 20:1.

[0078] In an embodiment, the ratio of the viscosity modifier and dispersant is ranging from 1:15 to 15:1.

[0079] In an embodiment, the ratio of the viscosity modifier and dispersant is ranging from 1:10 to 10:1. In an embodiment, the ratio of the viscosity modifier and dispersant is ranging from

[0080] 1:5 to 5:1.

[0081] In an embodiment, the ratio of the viscosity modifier and dispersant is ranging from

[0082] 1:3 to 3:1.

[0083] In an embodiment, the ratio of the polymer and anionic surfactant is ranging from

[0084] 1:20 to 20:1.

[0085] In an embodiment, the ratio of the polymer and anionic surfactant is ranging from

[0086] 1:15 to 15:1.

[0087] In an embodiment, the ratio of the polymer and anionic surfactant is ranging from

[0088] 1:10 to 10:1.

[0089] In an embodiment, the ratio of the polymer and anionic surfactant is ranging from

[0090] 1:5 to 5:1.

[0091] In an embodiment, the ratio of the polymer and anionic surfactant is ranging from

[0092] 1:3 to 3:1.

[0093] In an embodiment, the ratio of polyvinylpyrrolidone and lignosulfonate is ranging from 1:20 to 20:1.

[0094] In an embodiment, the ratio of polyvinylpyrrolidone and lignosulfonate is ranging from 1:15 to 15:1.

[0095] In an embodiment, the ratio of polyvinylpyrrolidone and lignosulfonate is ranging from 1:10 to 10:1.

[0096] In an embodiment, the ratio of polyvinylpyrrolidone and lignosulfonate is ranging from 1:5 to 5:1.

[0097] In an embodiment, the ratio of polyvinylpyrrolidone and lignosulfonate is ranging from 1:3 to 3:1.

[0098] In an embodiment, the ratio of microfibrillated cellulose and lignosulfonate is ranging from 1:10 to 10:1.

[0099] In an embodiment, the ratio of microfibrillated cellulose and lignosulfonate is ranging from 1:5 to 5:1.

[0100] In an embodiment, the ratio of microfibrillated cellulose and lignosulfonate is ranging from 1:3 to 3:1. In an embodiment, the ratio of microcrystalline cellulose and lignosulfonate is ranging from 1:10 to 10:1.

[0101] In an embodiment, the ratio of microcrystalline cellulose and lignosulfonate is ranging from 1:6 to 6:1.

[0102] In an embodiment, the ratio of microcrystalline cellulose and lignosulfonate is ranging from 1:5 to 5:1.

[0103] In an embodiment, the ratio of microcrystalline cellulose and lignosulfonate is ranging from 1:3 to 3:1.

[0104] In an embodiment, the dispersing agent is used in a concentration from about

[0105] 1% to about 10% w / w, preferably from about 1% to about 5% w / w of the total weight of the composition.

[0106] In an embodiment, lignosulfonate is used in a concentration from about 1% to about 10% w / w, preferably from about 1% to about 5% w / w of the total weight of the composition.

[0107] Rheology modifiers may be present in compositions of the present invention at a concentration from about 0.01% to about 5% w / w, preferably from about 0.01% to about 2% w / w, more preferably form about 0.01% to about 1.5 % w / w the total weight of the composition.

[0108] In an embodiment, an agrochemical composition further comprises one or more agrochemically acceptable excipient selected from surfactants, wetting agents, antifreezing agents, carriers, fillers, solvents, stabilizers, thickeners, preservatives, biocides, antifoaming agents, colorants, and other formulation aids.

[0109] In an embodiment, water may be present in compositions of the present invention at a concentration from about 0.1% to about 99% w / w, preferably from about 10% to about 80% w / w, more preferably from about 10% to about 70% w / w and even more preferably from about 10% to about 60% w / w and most preferably between about 30% to 50% w / w the total weight of the composition.

[0110] In some embodiments, the antifoaming agent is selected from polydimethylsiloxane, an emulsion of polysiloxane, silicone oil and magnesium stearate or a suitable combination thereof. Anti-foaming agents may be present in compositions of the present invention at a concentration from about 0.01% to about 1% w / w, preferably from about 0.05% to about 0.5% w / w, more preferably form about 0.2% to about 0.4% w / w and even more preferably at about 0.2% w / w of the total weight of the composition.

[0111] In some embodiments, preservatives suitable for use in the present invention include, but are not limited to, 2-bromo-2-nitro-l,3-propanediol, 5-chloro-2-methyl-4- isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one solution in water, 2-benzisothiazolin- 3-one and mixtures thereof. The preservative can be present in compositions of the present invention at a concentration from about 0.01% to about 5% w / w, preferably from about 0.1% to about 5% w / w, more preferably form about 0.1% to about 1% w / w and even more preferably at about 0.2% w / w of the total weight of the composition.

[0112] According to an embodiment, the composition according to the present disclosure may be applied either pre or post emergent. The advantage of the composition is surprisingly good residual effects, when applied in pre-emergent as well as quick knockdown when applied post emergent leading to quick control of weeds.

[0113] The compositions of the present invention may be applied in any known ways or conventional methods known to a person skilled in art. Non-limiting examples of such methods are foliar spray, basal barking, stem injection, drill and fill method, axe cut method, cut stump, cut and swab, stem scraper, wick application and so forth. The compositions of the present invention are used in the customary manner, for example by watering, spraying, atomizing, dusting or scattering.

[0114] Advantageously, the herbicidal composition of the present invention is stable and can be stored for a long period retaining its herbicidal activity and suspensibility and without forming crystals.

[0115] In an embodiment, the present invention provides active D50particle size distribution ranging from 1 to 10 microns.

[0116] In an embodiment, the present invention provides active D50particle size distribution ranging from 1 to 5 microns.

[0117] In an embodiment, the present invention provides active D90particle size distribution ranging from 1 to 20 microns. In an embodiment, the present invention provides active D90particle size distribution ranging from 5 to 15 microns.

[0118] In one embodiment, the herbicidal composition of the present invention retains stability when stored at ambient temperatures. In a preferred embodiment, the herbicidal composition is stable under Accelerated heat stability (AHS) conditions, i.e. at 54°C for 14 days.

[0119] The present suspension concentrate also proves to have a consistent particle size at 14 days, AHS conditions, without significant deviation in the particle size of the actives.

[0120] In an embodiment, the present invention provides preferred compositions and methods thereof. The methods of the invention include a method of controlling weeds at a locus by applying to the locus the composition, a method of increasing yield in a crop by application of the combination or composition, or a method of improving the plant health by application at the locus of the plant the composition. The embodiments described herein describe the preferred embodiments of all these possible compositions and methods of the invention.

[0121] The present composition can be applied to the locus of the weeds, in an herbicidally effective amount.

[0122] In an embodiment, the combination of the present invention may be combined with at least another active ingredient such as those selected from but not limited to herbicide, insecticide, fungicide, biological agent, plant growth activator, fertilizers or combinations thereof.

[0123] In an embodiment, the present disclosure provides use of an herbicidal composition comprising penoxsulam and propanil for controlling weeds.

[0124] The compositions of the present invention can be applied to a locus by using conventional ground sprayers, granule applicators, watering (drenching), drip irrigation, spraying, atomizing, broadcasting, dusting, foaming, spreading-on, aerial methods of spraying, aerial methods of application, methods utilizing application using modern technologies such as, but not limited to, drones, robots and by other conventional means known to those skilled in the art. In an embodiment, the composition of the present disclosure is effective in controlling target weeds selected from Alopecurus myosuroides Huds. (blackgrass, ALOMY), Amaranthus palmed (Palmer amaranth, AMAPA) Amaranthus viddis (slender amaranth, AMAVI), Avena fatua (wild oat, AVEFA), Brachiada decumbens Stapf. or Urochloa decumbens (Stapf), Brachiada brizantha or Urochloa brizantha, Brachiada platyphylla (Groseb.) Nash or Urochloa platyphylla (broadleaf signalgrass, BRAPP), Brachiada plantaginea. or Urochloa plantaginea (alexandergrass, BRAPL), Cenchrus echinatus (southern sandbur, CENEC), Digitaria horizontalis Willd. (Jamaican crabgrass, DIGHO), Digitaria insularis (sourgrass, TRCIN), Digitaria sanguinalis (large crabgrass, DIGSA), Echinochloa crus-galli (barnyardgrass, ECHCG), Echinochloa colonum (junglerice, ECHCO), Eleusine indica Gaertn. (goosegrass, ELEIN), Lolium multiflorum Lam. (Italian ryegrass, LOLMU), Ludwigia parviflora (LUDPN), Eichhornia crassipes, Panicum dichotomiflorum Michx. (fall panicum, PANDI), Panicum miliaceum L (wild-proso millet, PANMI), Sesbania exaltata (hemp sesbania, SEBEX), Setaria faberi Herrm. (giant foxtail, SETFA), Setaria viridis (green foxtail, SETVI), Sorghum halepense (Johnsongrass, SORHA), Sorghum bicolor, Moench ssp., Arundinaceum (shattercane, SORVU), Cyperus esculentus (yellow nutsedge, CYPES), Cyperus rotundus (purple nutsedge, CYPRO), Cyperus difformis (CYPDI), Rotala indica (ROTIN) and Cyperus iria (CYPIR), Abutilon theophrasti (velvetleaf, ABUTH), Amaranthus species (pigweeds and amaranths, AMASS), Ambrosia artemisiifolia L (common ragweed, AMBEL), Ambrosia psilostachya DC. (western ragweed, AMBPS), Ambrosia trifida (giant ragweed, AMBTR), Anoda cristata (spurred anoda, ANVCR), Asclepias syriaca (common milkweed, ASCSY), Bidens pilosa (hairy beggarticks, BIDPI), Borreria species (BOISS), Borreria alata or Spermacoce alata Aubl. or Spermacoce latifolia (broadleaf buttonweed, BOILF), Pontederia vaginalis, Chenopodium album L (common lambsquarters, CHEAL), Cirsium arvense (Canada thistle, CIRAR), Commelina benghalensis (tropical spiderwort, COMBE), Datura stramonium (jimsonweed, DATST), Daucus carota (wild carrot, DAUCA), Euphorbia heterophylla (wild poinsettia, EPHHL), Euphorbia hirta or Chamaesyce hirta (garden spurge, EPHHI), Euphorbia dentata Michx. (toothed spurge, EPHDE), Erigeron bonariensis or Conyza bonariensis (hairy fleabane, ERIBO), Erigeron canadensis or Conyza canadensis (horseweed, ERICA), Conyza sumatrensis (tall fleabane, ERIFL), Helianthus annuus (common sunflower, HELAN Jacquemontia tamnifolia (smallflower morningglory, IAQTA), / pomoea hederacea (ivyleaf morningglory, IPOHE), / pomoea lacunosa (white morningglory, IPOLA), Lactuca serriola (prickly lettuce, LACSE), Portulaca oleracea (common purslane, POROL), Richardia species (pusley, RCHSS), Salsola tragus (Russian thistle, SASKR), Sida species (sida, SIDSS), Sida spinosa (prickly sida, SIDSP), Sinapis arvensis (wild mustard, SINAR), Solanum ptychanthum (eastern black nightshade, SOLPT), Tridax procumbens (coat buttons, TRQPR), Rumex dentatus (RUMDE), Xanthium strumarium (common cocklebur, XANST), Lamium purpureum (LAMPU), Stellaria media (STEME), Cyanus segetum (CENCY), or Galium aparine (GALAP).

[0125] In an embodiment, the present invention provides a process for preparation of a suspension concentrate, the process comprising;

[0126] (a) preparing a slurry mix comprising the actives, one or more rheology modifiers, dispersing agent and other excipients followed by homogenizing the slurry mix,

[0127] (b) feeding the slurry into a bead mill and milling was continued to obtain the desired particle size, and

[0128] (c) subjecting the milled slurry to gelling which was filtered and stored.

[0129] According to an embodiment described herein, the various components of the agrochemical composition can be used individually or already partially or completely mixed with one another to prepare the composition according to the invention. It is also possible for them to be packaged and used further as combination composition such as a kit of parts.

[0130] According to an embodiment of the present disclosure, a kit-of-parts comprising an agrochemical composition is provided. The kit comprises a plurality of components, each of which components may include at least one of the ingredients of the agrochemical composition of the present disclosure.

[0131] In one embodiment described herein, the kits may include one or more, including all, components that may be used to prepare the agrochemical composition. One or more of the components may already be combined together or pre-formulated. In those embodiments where more than two components are provided in a kit, the components may already be combined together and as such are packaged in a single container such as a vial, bottle, can, pouch, bag or canister.

[0132] In other embodiments, two or more components of a kit may be packaged separately, i.e., not pre-formulated. As such, kits may include one or more separate containers such as vials, cans, bottles, pouches, bags or canisters, each container containing a separate component for the agrochemical composition.

[0133] In both forms, a component of the kit may be applied separately from or together with the further components or as a component of a combination composition according to one aspect of the embodiment for preparing the agrochemical composition according to the invention.

[0134] The present composition obtained has a superior suspensibility, better dispersibility and no sedimentation.

[0135] The invention described herein provides a method of controlling weeds thereby providing resistance management and significant control of the weeds. The invention also provides an adequate method to achieve complete control of weeds, improving yields, while targeting resistance management.

[0136] The invention shall now be described with reference to the following specific examples. It should be noted that the examples appended below illustrate rather than limit the invention and that those skilled in the art will be able to design many alternative embodiments without departing from the scope of the present invention.

[0137] EXAMPLES

[0138] Example 1: Suspension concentrate formulation of the present invention

[0139] Propanil + Penoxasulam (400 + 10 g / L SC)

[0140] Table 1:

[0141] Q.S. Quantity sufficient

[0142] Process: The required amount of water was added to a preparation vessel followed by adding the cellulose polymer and monoethylene glycol, which was stirred for 1 hour to obtain a solution. The other excipients were charged into the vessel. The technical ingredients including propanil and penoxsulam were added into the solution while stirring to form a slurry. The slurry was fed into a bead mill and milling was continued to obtain the desired particle size. The milled slurry was subjected to gelling. The gelled material was filtered and stored.

[0143] Stability of the formulation disclosed in Example 1

[0144] Table 2: Example 2: Suspension concentrate formulation of the present invention Propanil + Penoxasulam (400 + 10 g / L SC) Table 3:

[0145] Q.S. Quantity sufficient

[0146] Process: The required amount of water was added to a preparation vessel followed by adding the cellulose polymer and monoethylene glycol, which was stirred for 1 hour to obtain a solution. The other excipients were charged into the vessel. The technical ingredients including propanil and penoxsulam were added into the solution while stirring to form a slurry. The slurry was fed into a bead mill and milling was continued to obtain the desired particle size. The milled slurry was subjected to gelling. The gelled material was filtered and stored. Example 3: Suspension concentrate formulation of the present invention

[0147] Propanil + Penoxasulam (400 + 10 g / L SC)

[0148] Table 4:

[0149] Process: The required amount of water was added to a preparation vessel followed by adding the cellulose polymer and monoethylene glycol, which was stirred for 1 hour to obtain a solution. The other excipients were charged into the vessel. sThe technical ingredients including propanil and penoxsulam were added into the solution while stirring to form a slurry. The slurry was fed into a bead mill and milling was continued to obtain the desired particle size. The milled slurry was subjected to gelling. The gelled material was filtered and stored. Example 4

[0150] Comparative examples A, B, C and D were prepared to compare the stability of the said formulations to Example 1.

[0151] Table 5:

[0152] The aforementioned Examples A, B, C and D were prepared according to the process disclosed in Example 1. Example 5

[0153] The physico chemical stability of the aforementioned Examples A, B, C and D were determined at ambient conditions and at Accelerated Heat stability conditions (14 days at 54C. The results are summarized in the tables 6(A) to 6(D) below.

[0154] Table 6(A)

[0155] The formulation described in Example A used an ammonium salt of polyarylphenyl ether sulphate as the dispersant, however the said surfactant was proved not be favourable as observed from the results above. The suspensibility of propanil at AHS conditions was found to be low. The density and viscosity were not within the specified limits. The particulate size also increased considerably above the specified limits at the said AHS conditions. The aforesaid variations in the physico chemical parameters does not make the formulation of Example A conducive for application in field.

[0156] Table 6(B)

[0157] The formulation described in Example B used an EO PO Block Co-polymer as the dispersant, however the said surfactant was proved not be favourable as observed from the results above. The suspensibility of propanil at AHS conditions was found to be low. The density and viscosity were not within the specified limits. The particulate size also increased significantly at the said AHS conditions. The aforesaid variations in the physico chemical parameters, mostly the particle size of the actives does not make the formulation of Example B conducive for application in field.

[0158] Table 6(C)

[0159] The formulation described in Example C used an amine salt of polyarylphenyl ether phosphate as the dispersant, however the said surfactant was proved not be favourable as observed from the results above in table 6(C). The suspensibility of propanil at AHS conditions was found to be low. The density and viscosity were not within the specified limits. The particulate size also increased significantly at the said AHS conditions. The aforesaid variations in the physico chemical parameters, mostly the particle size of the actives does not make the formulation of Example C conducive for application in field. Table 6(D)

[0160] The formulation described in Example D used a sodium alkyl naphthalene sulfonate, formaldehyde condensate as the dispersant, however the said surfactant was proved not be favourable as observed from the results above in table 6(D). The suspensibility of propanil at AHS conditions was found to be low. The density and viscosity were not within the specified limits. The particulate size also increased significantly at the said AHS conditions. The aforesaid variations in the physico chemical parameters, mostly the particle size of the actives does not make the formulation of Example D conducive for application in field.

[0161] Example 6: Herbicidal efficacy of the present composition

[0162] Herbicidal efficacy of the composition of Example 1 was determined. The herbicide composition was determined against weeds Ludwigia parviflora (LUDPN), Cyperus difformis (CYPDI), Rotala indica (ROTIN) and Cyperus iria (CYPIR). Table 7

[0163] *The values for untreated control are an indication of the weed count / m2

[0164] The observations for the untreated control include the respective weed counts observed. Further, the observations in treatments 2 and 3 include % weed control for the formulations of Example 1 and 2, respectively. The present composition was found to effectively control weeds as observed above.

Claims

We Claim:

1. A suspension concentrate comprising; a. penoxsulam, b. propanil, c. at least one viscosity modifier selected from the group comprising polymer(s), d. at least one dispersant comprising anionic surfactant(s), and e. agrochemically acceptable excipients.

2. The suspension concentrate as claimed in claim 1, wherein propanil is used at a concentration in the range from 1% w / w to 50% w / w of the composition.

3. The suspension concentrate as claimed in claim 1, wherein penoxsulam is used at a concentration in the range from 0.5% w / w to 2% w / w.

4. The suspension concentrate as claimed in claim 1, wherein viscosity modifiers are selected from polyvinylpyrrolidone, cellulosic polymers, microcrystalline cellulose, microfibrillated cellulose, hydroxy propyl methyl cellulose, hydroxyethyl cellulose, magnesium aluminum silicate, attapulgite clay, hydrophilic fumed silica, aluminum oxide, xanthan gum or mixtures thereof.

5. The suspension concentrate as claimed in claim 4, wherein viscosity modifiers are used at a concentration in the range from about 0.01% w / w to about 5 % w / w of the total weight of the composition.

6. The suspension concentrate as claimed in claim 1, wherein the dispersant is an anionic surfactant.

7. The suspension concentrate as claimed in claim 6, wherein the anionic surfactant is selected from the group of lignosulfonates.

8. The suspension concentrate as claimed in claim 7, wherein lignosulfonates are selected from the group of calcium lignosulfonate, sodium lignosulfonate, sodium alkyl naphthalene sulphonate, sodium alkyl naphthalene sulphonate formaldehyde condensate, potassium lignosulfonate, magnesium lignosulfonate or ammonium lignosulfonate.

9. The suspension concentrate as claimed in claim 7, wherein the lignosulfonates are used at a concentration in the range from about 1% w / w to about 10% w / w of the total weight of the composition.

10. The suspension concentrate as claimed in claim 1, wherein viscosity modifiers and dispersants are combined at a ratio in the range from 1:20 to 20:1.

11. The suspension concentrate as claimed in claim 1, wherein the suspension concentrate further comprises agrochemically acceptable excipients selected from the group of surfactants, wetting agents, anti-freezing agents, carriers, fillers, solvents, stabilizers, thickeners, preservatives, biocides, antifoaming agents, colorants, and other formulation aids.

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