Cosmetic composition for skin barrier improvement and skin regeneration, containing rose-derived DNA as active ingredient
The extraction of high molecular weight PDRN from roses addresses the limitations of animal and plant-derived DNA, providing effective skin regeneration and barrier improvement in vegan cosmetics.
Patent Information
- Application Number
- PCT/KR2024/012702
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-06-28
- Filing Date
- 2024-09-06
- Publication Date
- 2026-01-02
AI Technical Summary
Existing methods for extracting DNA from animal sources, such as salmon semen, are not suitable for vegan or cruelty-free cosmetics, and existing plant-derived DNA extraction methods result in low molecular weight DNA with significant damage and impurities, losing their functional efficacy.
A method for extracting high molecular weight polydeoxyribonucleotide (PDRN) from rose plants by using a specific extraction process involving buffer solution, maturation, heating, impurity removal, and purification steps to obtain PDRN with minimal damage, suitable for vegan and cruelty-free cosmetics.
The rose-derived PDRN maintains high molecular weight and functionality, exhibiting superior skin regeneration, wrinkle improvement, elasticity enhancement, and skin barrier restoration effects, with reduced melanin expression, ROS scavenging ability, and increased collagen and filaggrin expression.