Pesticidal compositions comprising a thiazolidine and a biological agent

Abstract

Disclosed herein are compositions comprising A) compound of Formula One (F1) or Formula Two (F2); and B) biological agent selected from the group consisting of Bacillus species, Baclovirus species, Pseudomonas species, Beauveria species, Mycobacterium species, Mycorrhizal fungi, Trichoderma species, and Metarhizium species.

Description

e. saed elrcrenet bcie* 0- - 451 5 - - - - - -* *- - - - - -* * - 0- 4* * 7 0 0 0- -ssIvo px91107* 0 01 101 op%E tonnoe itsdaereret ac6 6 2 5 5 2 6 6 7lucv e0 0- -1 3040 0 0 6- - - - - -20- - - - - -02- 0 -1 1 1 10 0 0- -clno pIxaEC * %d letocrt07 0 9 7 1 0 903 6 3 3 50 05 50 00 0 8 8 5 50 00 0 8 80 06 6 3 30000e n1 5 5 1 3 5 5 3 1 4 3 50 02 2 5 5 8 8 2 2 5 5 8 8 1 1 3 3p o 1 1 1 1x C E %fdo eevlro rertutx0707 3 7 00003 6 9 6 6 9 60 0508 5 3 50 0 05 52058300 61613361333 3 3s ni 1 1 3 6 5 1 3 1 4 1 1 4 6 2 3 2 6 2 2 1 3 8 8b oM O C %I eAglaorr07070707 30303030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 et 1 1 1 103 3 3 3vnoA C %1 eFglao0 0 0 rr0 00 0 7 7 0 00 06 6 3 3 0 0 5etn5 5 1 1 5 5 1 1 3 3 1 1 2520 00505888852520 0050588880 06161333300 101v oA CWA B -o1itaIE A77 2 13331116688 7 2 :66 66222 22111 11 656LRt1F:1 6: : 5 3531:1 2: :1 1:1:13 33311:331 111 55 55:11 5: 5757 77:2: 77 2: 76:1:2 1:122:1 1:111:1 1:16:176:1662:21:1221:11 1:111:6: 651 1: 8110 :181:6: 061 1:3 1:103:2 1:151:1B1 1 1:1 1:1 1 1 1 1AWT etalle22222 2454454454454 R Iw2.g2 2.2.2. 0000000000000 200 20202. 202. 202. 202. 0 5 0 5 0 5 0 5_ / 0 020202101 101 101 101 0. .0. .0 0. .0. . .0.0.0.0 0 0.0 0.0 0.0 0.Au 0 0 0 0 0 0 0 0 0 0 0.0 0.0 0.0 0.0 0etallRe3030909081816 6 3 3 9 9 8 816363303090908181636330309090818163633030909081816363_w3 3 0 0 0 0 11 / 00000000000000000000000000000000000000Fgu.0.0.0.0.0.0.0.0.0.0.0.0.0.0.0.0.0.0. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000.01515151 1 1 1 335 5 5 5- -3 3 3 3 3S- - - - - -TS S S S S S747BTBTBTBTBTBTB747A A A A A A A D n Dniiananrianrianrianianiania ariari tststsrtsrtsrtsrtsstst ,,s ik ,ik ,ik ,ik ,ik ,ik ,ikAs s,ns,at ein sasatatsatsatsatstsceiaf ci rur r r r r r rkuku u u u ueafue.p.k.k.k.k.kqNi ulqolil i sp p p p p.pbsubsubsubsubs sububuyollyl s,s,s s s s ss, , , , ,a mamissi si sis a nsnsnsnssinssin n nulsliu elcliilli geinigeigeigeigeigeirnirni ni ni nigni iBacBaBuhsulsliulsulsulsulsulsulsulicliclicliclicliclicli turhcs turhurhurhurhuhuls tuls tuls tuls tuls tuls tulsulcliacliclicli li lilli a a a a a a a a liclicliclicliclicliclicBaBaBacBacBacBac B B B B B B B BBaBaBaBaBaBaBaBaBaBPage 37 of 48e. saed elrcretcbisneIvoep* 0- - soxpt%Eonnoesd iae taerretc lcv0 0- - uclnoep aIxEC * %d letocrten0710595p o 1 1 8x C E %fdo eevlro rut7 3 7 309 9 9 9 3ert010 03 1 800 0 0 0 0 0 0 0 0 0 0 0 0 0 00 3 3 3s n xi 1 4 4 4 4 3 5 1 6 6b oM O C %I eAglaorr070707070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 03030303etvn1 1 1 1 1 1 1 10 o A C %1) e Fd glo0 0 70 0e arrt0 07 0 00 06 6 3 3n5 5 1 1 5 5 1 1 3 301010 005057171050552520 005058888un eit v onA Coc(oWitI772211633 33311 116565 87873338 9 47676 222 11166AaABR: 6-t1F:166:21:122:11:111:6:51 1:3133 3 11155773: 331:1: 11:5: 55:2: 72:2:13 82:7:1779:31:1839:11:191:166 6 2:6622 1115:2: 22 1: 11 5 5:55:1W1 1 1 1 1 1 1 1 1 1 1 1:1 1:1 1 1ELBetAalleTR22222222 _Iw / g0.0.0 0.0.0 0.0.0 0.0.00100101001010010100 710.7 0. 700.7 0. 700.7 0. 700.7 0.0202202202202Auetalle30309090818163633 3 9 9 8 8 6 6 3 3 9 9 8 8 6 6 3 3 9 9 8 8 6 6R_w1 / 00000 0 0 0 0 0000000001010303000000000101030300000000010103030Fgu.0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.021212121212 2 2 -- - - -1 1 1ASASASASA-SA-SA-SAS9090909 9 9 9 9 nian n n n n n n3 3 3 3 3 3 3 30 0 00000000000ritasritaritaritaritaritariar2B2B2B2B2B2B2B2BSFSFSFSFSFSFSFSF,i sk,i s,i s,i s,i st,i st,i s,S S S S S S S SimmmmmmmmAn A A A A A A Aatkatkatkatkatkak kucucucucucucucuceaeaeaeaeaeaeaeaianianianianianianianiaIsrsrsrsrsr tsar tsar tsrito iito iito iito iito i i iili toi toi toiliilpliilpliilpliilpliil il il rt rt rt rt rt rt rt rtplipli li s s s s s s s sAufoku.kukukukukukukb b b b b b b b op pp.p.p.p.p.p.p.pmymymymymymymymy po o o o o o o sispspspspspspspshsiphsihsihsihsihsihsihapapap p p p pe s s s s s s s s s s s s s s s sullullullullullullullull rororaoraoraoraorarmbaubsububububububum,s,s,s,s,s,s,s, uimruimruimruimruimruimruimru iicicicicicicicicrraoror r r rororsbabababa a a alhl ol ol ol ol ol olNsi si si si si si si siensteteteteteteteti i i ibibibibichchchchchchchceinsnsnsnsnsnsncacacacacacacacnaenaenenenenenenesgeinigeigeigeigeigeigeigbob b b b b b b PaPaPaPaPaPaPaP asnasnas s s s snanananananrnu irnirnirnirni ni ni ly oly oly oly oly oly oly olyomomomomomomomom ht uhuhuhurhurhurhuhhtst t t t t tte hte hte hte hte hte hte hteododododododododulsliulsulsulsulsususuM M M M M M M Mueuseuseuseuseuseuseusescliclicli lillillilliP P P P P P P Paac c c c cB BaBaBaBaBaBaBPage 38 of 48e. seaedrcre lbnetci0 0 - 060 0 0- - - - - 0 - - - -ssIvoepx10 * 0 0 0 0 0 050 0 0 0 0 0opt%Eonnoe ditsaereret aclcv e0 0 - 040 0 0 07 - -0 0 0 0- - - 7 - - - - ucno p 1 10 010 0 0 0 0 0laIxEC * %d letocrt0 0 0 0 0 0 en0 0757568680po 1010 001010100 100 1013344000 1013333000 10105000 0 0 0 0 0 1010101010101x C E %fdovlroeerertutx0 0927500 6800000713 300000000 7 3 300 3 0 3 3 300 00000000000s ni 1 1 1 8 8 1 1 1 1 1 3 8 1 3 5 8 8 3 1 5 1 1 1 1b o 1C M O %I eAglaorrt0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0710710 0 0 00500105000 10 050500e n1 1v oA C %1 eFglaorrt0 075756868000 1010 0 000 100 100 100 100 1013333000 1013333000 1010 0 000 0 0 0 0 1010 0 0 0e1 1 1 1vnMoB A C D -1E oiLtaI BR A:3 13 333116 8 3331116688 0 :3311 1:1 615: 558:2: 7 32:33 331311 11 55 555577 72777.0:7.6:2.0:2.2:7.0:7.6:2.0:2.2:81: 81:6:106:3:103:2:151:At F 1:1:1 1 1 1 3:3 1: 11:5: :2: 1 1 1 1 1 1 1 11 1 1 1 1TW1 1 1:1 1:1 1 1 1 1etallRe12_ .1.1.1. 000000000020 20020 20020 20020 45045 4545 4545 4545Iw / g01010101101 101 101 101 0.0Au 0.0 0.00.0 0.00.0 0.00.0 0.00. 000.00. 000.00. 000.00.0etalle3030909081816363303090908181636330309090303090903030909081816 6R_w1 / 00Fgu. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 030 0. 030 0. 000.0757575751 1 1 1 1 1-1 1811 1 1 15351 1 1 88 8 5 5 5 5 5 5S -S-S-S9-9 -3 3 3 3 3 3 3C -9C -9 - - - - - - -C - CSTSTS S S S S S7 7 7 7 7 7 7 7T T T T T T T T T T4 4 4B B B BG G G GB B B B B B B B7 7 74747474747A A A Ani ni ni niA n A n A n A n A A A A D n D D D D D D D3i131313131313131 ni ni ni niartanr itanianianianianiania 7 7 7 7 7 7 7 7 a a a asartsartsarts iar iar iar ianr ianr ianianiasrtsrtsrtsrtsrtsrtsrts TSTrSTSTSTSTSTSTSts rtrtrt ,i ,i ,i ,itststststsrtsrtsrts,is,is,is,iawawawa ,i,i,i,i,i,i,i,iI,As,s,s,s,s,s,s,sQ Q Q Q Q Q Q Qawawawawaziaziaw ziakziatkfn satksatksatk k k ksat at at atoeinceineineineineineineinianianianianianianiania aeaf cacacacacacacartzazazaza a a a r r r rsrsrsrsrsrts rts rts rts rts rts rts iaiaiaia.p.p.p.pukukukukukukukukm efefefefefefefe sauq iiuqiuqiuqiuqiuqiuqiuqilist ilist ilist ilist ilist ilist ilist il .it p.sp.p.psbsbsbsb.p.p.p.p.p.p.p.pbsbsbsbusususussbsbsbsbsbsbsbsbNlollyollyollyollyollyollyollyolbyubsubsubsubsubsubsubsus usu,su,su,s,,si,ssi,ssi,ssiussu,su,su,su,su,su,su,s,ms s s s s s s s si si si si n n n n si si si si si si si siam samamamamamamaullulsliulsusususususuiulcliullullullullullullsnsnsnsnei ei ei ei snsnsnsnsnsnsnsnaciaciaciaciaciaciacaei ei ei eignignignigni ei ei ei ei ei ei ei eiclillillillillillilliac c c c c c c B B B B B B B BgnigrnigrnigrnirrurhturhturhtughtnigrnignignignignignigniBaBaBaBaBaBaBaB uhtuhtuhtuhtsulsususuruhturhturhturhturhtur rhtuhtuht sulsliulsulsullilclilclilclicsuls s s s s s scli lullullullul ul ul ulacliclicaBa a a icicicicliclicliclicBaBaBaB B BBaBaBaBaBaBaBaBaBPage 39 of 48esaedrcrenetc0704 - -0 0- - - - - - - - -Ivoepx9 2* 0 0 0 0 0 0 0 0 0 0 %Eesdaeer tre ccvoep082071- -0 0710 0 - 0 0 0 0 0 0- - - - - -0- -0 nIxE%d letocrt0 0 0 0 0 en092759668090po 1010 000 0 0 101010101010 075756868000 1013333000 101x C E %fdo eevlo rrut07 7 6 7 60000 70 00 700000 0 0 0 0 09 4 7 7 3070 re txs ni 5 5 8 5 8 1 1 1 1 6 1 10101 2 1 5 5 3 601b oC M O %I eAglaorr090909090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 et 2 2 2 2vnoA C) %1deue Fnglo7 7 6 60 0 0 0 0 0 0 07 7 60 0 0 0itarrt0 05 5 8 801010 00101010101010 05 5 868010133330101n eo vnocA C ( M BoDit-aI A3311 336638 33 3113 111 6565 87873338899942222 11111 R: 3Et1F:133:11:111: :11 5:1:1 2:133 3 1:11555 777 32: 37: 77:3: 83:1: 91222 111LW133:11:111:5:11 5:21:1 2:21 1:1 1 1 1 1 1:1 2:1 2:11:1 1:1BAT etallRe_Iw / 1g0.1 0. 100.1 0. 100.1 0. 100.1 0.00100101001010010100 710.7 0. 700.7 0. 700.7 0. 700.7 0.0202202Auetall 3 3 9 9 8 8Re 0 0 0 06 6 3 3 9 9 8 8 6 6 3 3 9 9 8 8 6 6 3 3 9 9_w1 / 00Fgu. 000. 000. 010 0. 01 3 3 0 0 0 0 1 1 3 3 0 0 0 0 1 1 3 3 0 0 0 00 0. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000. 000.021212121212 2 2 -- - -1 1 1A A A- - - -Sn S SASASASASAS9 9 9 9 i 3 3 3 3 3 4 5 60 0 0 0anritans ritans ritans ritans ritans ritans ritasr2tsB2SB2SB2SB2SB2SB2SB20 0 0 0SBS S S SSF F F F,i,i,i,i,i,i,i,immmmmmmmAn A A Akatkatkatkatkatkatkatkat uciuIsrsrsrsrsrsrsrsr tco iui tco iui tco iui tco iui tco iui tco iui tco ieai eli toili ai elpli ai elpli ai elpli ai elpli ai elpli ai elpli ai ilpl anir itanr itanr itartpss ss ss sAufoku.kukukukukukukbmbmbmbmbmbmbmb opopopopopopopopihihihsihep.sp.p.p.p.p.p.p ym bsbsbsbsbsbsbsbsysysysysym sysys susus s s s s s paausum m llilliulliulliulliulliulliulli r paor par parrorororN,susususususususi,ssi,ssi,ssi,ssi, , , irussississis e imt ruc e imt ruc e imt ruc e imt rumumucacacacacacacacac e itrce itrce itrcet bibibibibibibibiolholholholhcnenenenenenenenecs c c cneingeineineineineineineiababababababababa a a a a a a aasnnasnasaigrnu igrnh tu igrnhu igrnu igrnu igrnu igrnu iorluy olht y oly ololololol P P P P P P P P o ononos ththththththte hte ht yeht yeht yeht yeht yehtm eom dom dom dodulsliulsulsulsulsususuM M M M M M M MueuseuseusescliclicliclilclillilliP P P Paa a ac c cB B B BaBaBaBaBPage 40 of 48e.seaedrcre lbnetci* *- - 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2 - -n vo p 2Ix%Eesdaereretccvoep- 61- -nIxE%d letocrtn32 9 4eo 7 3 9pxC E %fdovlroeerertut0885218sn xib oC M O %I eAglaorr006 6 etvnoA CWCT1d %ne Faglaorr32 4 4etn7 3 9W Av oFA C - I2A:E1LF00BoAit0055025366T a: 2651R2:t1 1:1:1W e)tlaleRw_ / i0 0 0 0Ia5 5 5 5Agu(e)tlalew 2 _0882 R / i0 0 31 a0.0F gu0.0 00.0.0(iiniiniiniiIa a anaAcfelcelcelcel oemumumumumilla iilclillilliiciiciicNtre trtritrVeVeVeV seicWW e WW pASFAFCTCTPage 43 of 48e.seaedrcre lnet bc7 - - - - - 3 1 - 1 - 1 1 - 1 00i7ssIvoep* * 0 0 0 7 4 - 7 9 * * 0 0 0ox6 1 1 1 9 3 933 6pEt%onnoesd itaereret ac7 3cv e1030 0 0- - - - -70l1- 5- 61617 4- - 61337 8 0 0 030 0uclno p 3 aIxEC * %d letocrten0 00505000 po 1017474252575750909547681153969544381139290 00505000 101x C E %fdo eevlro rertutx 71038050000 64926464644600 280 7 4 60000 704 400000 00 30000s ni 1 1 1 5 1 3 6 1 1 1 3 3 1 1 5 8 1 1b oM O C %I eAglaorr0 0 0 0 0 06etn464646464646464710571057105710710710 0 0 0 0 0 0 voA C %1 eFglaorr0 00et 505000 1012 211110202282843431 1292943431 129290 00505000 101vnoA C oitaI 0 RA:0 00000000 0000000000 00 000000000000000000 000000t1F0 050 000:050 05 00 000 0000 00 00 000 05 00 00 00 0000 00 00 000 00 00 0000 00 00 000000 00 000000:5:1 5: :1 5:10505: 05 5:1 5: :1 5: 0505: 05 5:5: 0505: 05 5: 05: 05: 05 5: 05:5:1 5:W1 1 1:1 5:1 1:1 1 1:1 5:1 1:1 1 1:1 5:1 1:1 1 1 1:1 1 1 1etallRe_0000000000 0 0 0000000000000 0 0 Iw / g1010101010 010 0 0 0000000000000 0 0 0 0 0u1 1 1 1 1 1 1 1 101 101 101 101 101 101 1 1 1 1 1 1A etallRe202_w / 002 2 0. 000 0 2.0.0.0. 22 0002 .00020200000002 22 22 22 20. 000 0 2.0.0.0. 200.000000 0 2. 00.0.0.0. 200.0 02020 2 2 20202020 2 2000. 00.0.0.0.0 0.00000 0.0.0.0.1 g0 0. .0 0 0 0 0 0. .0 0 0 0F u 0 0 0 0 0 0 0 0 0 0 0 07575757575751 151515151 1 88 8 8 8 8-1 3 3 3 35352 2 2 2 2 2 S -1S-1S-1S-1S-S-S-S-S-S-3S- 1-1-1-1-1-1- 747 7 7 7 7T T T T T T T T T T TST ASASASASASAS74D747474747 B B B B B B BABABABABnD3 3 3 3 3 3 3 3A A A A A An n n nABnAnn ianr ianr ianr ianr ianr iarianD n D n D n D n17171717171 1 1 nianianianianianiaiar iar iar iar iar iar tstststststsritasritaritaritarita 7 7 7rtT T T T T T T Trts rts rtrtrtrttstststststs,ik ,ik ,ik ,ik ,ik ,ikI,s s s s sS S S S S S S S,i ,is,is,is,is,i,iA s, k ,ik ,ik ,ik ,ik ,ikatsatsatsatsatsatsfns,ns,ns, ,nsnsnQ n Q n Q n Q n Q n Q Q Qawawawawawawatsatsatsatsatsatsrurururururuoeicei ei ei ei eiiaiaiaiaianianiania aeaziaziaziaziazazrurururururuk.k.k.k.k.k.f caf caf caf cacarts rts rts rts rts rts rts rtsa a a aiaia k.k.k.k.k.k.pspspspspspsmeaueqi ueuefuefueusilsilsilsilsilsilsilsil .p.p.p.p.p.p pspspspspspsbubububub blqilqilqilqilqil itb itb itb itb itb itb itb its s s s s sbb b b b b b bubububub b s s s sususNolyol ol ol ol ol usususususususus usususususus s,s,s,su,su,s,,si,si,si,si,si,simymymymymy ,ms s s s s s s s si,si,si,si,si,si sississississississnsensensensensenas a a a a aullulsliulsusususuiulcliulliulliulliulliulliullisnsnsnsnsnsn nacacacacacacacaeiclilclilclilclilcliB B B B B B B Bgei ei ei ei ei einnignignignignignigeinnigeingein nigigigigigeiggeigeignirnirnirnirnirnirrnirnirnirnirniruhu u u u uaa a a aca rurururururu u u u u u uthththththt BB B B B Bhthththththththththththtsus s s s ssuls s s s s sliulcliul ul ul ul uls s s s sllcliclicliclicliulcliulcliulcliulcliulcl iulicliulcliulcliulcliulcliccaBaBaBa a aa a a a a a aBaBaBa a aB B BB B B B B B B B BPage 44 of 48e. saed elrcrenet bce 7Ivo px1815- 768 120i114- 22* * 080 18162120 0 *33* 00176330 0- - 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- - 258832- 98113566179 -88 - 98- - - -04236972 - -64 1 -21 - -nIvo px2 1 2 1 3 1 4 4 1 5 1%Eesdaereretccv ep51- - - -7115 - 4 7 7956133- 24- 21- - - - 23619363- - 715- 52- -noIxE%d letocrten 22221515153131223334142222311122221131753504049218 80424211122221525p ox C E %fdo eevlro rutertx 8 5 8 3 6 9 4 7 7 8 9 1 7 4 5 0s ni 3 1 3 3 4 1 2 244 4 2 8924461460152 1 433821482744453528261074 3 2b oC M O %I eAglaorrt0 0 0 0 0 0 0 0415 1 0 0 6 3 0 0 3 6215 0 0 2 5 0 1 0 3 4 3 0 0 0 2 evnoA C %1 eFglaorr 2 2 1 1 1 3 3 2 2 0 0 2 28 82 28 81 1 0 08 8 8 80 08 82 2 1 1et 2 2 5 5 5 1 1 2 2 4 4 2 2 2 2 5 5 4 4 4 4 2 2 5 5vnoA C oitaI RA:5287 80.3.6.87 9 029138 t1 6: ::2:0. 001: 01: 01: 01: 0 10. 1.1: 0101 2 10 0215.2 F1 10:01:1 0:1 :13:14:13:1 1 1 0:1.0:1 1:1 1 1:1 1 1:1 1 1:1 0: 0:111 1:1:1 1:1:1:1:1 1:14:14:1 0:1:1W1e)tdaeRe4 2 6 6 2 3 2 5 01_ s / 8250505050 5 5.50505 0 503 0 Ii.a0.1010408.1.3.0.3210373 15 211 52121 52121 52121 5221.12121 52121 521210321 521.032652Agu(e)tdaeRe5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 _s / i212121212121212121212121212121212121212121212121212 2 2 2 2 2 2 2 2 21 a1 1 1 1 1 1 1 1 1 1F gu()0) ) 000067607677571 1 T85181535CTCTC -S-S-3S- 2 2 S1-1A- C (C0(C10( 5 10145 B47T T T TB47 747 BAB B B SAA A An Si ni9393m 7 7 3 3 SS SZ umu 9 92 22 2 87878787eFZFD D3131 ni ni nianiaartasrtsA A3535rara niania5F5F BSBS -T-T-T-Tse B B Bnnsn Ii ni niBIBIBararanrita 7 7 arrtT t artrtSTS s,s, srt,i s,,i,iH H ikakaG n GInRIPR hPphyp rthyhsrtas ni nimmnaararucuceai eaiianr ianr ianr iarIeliAs eli ts MIMIMIstsss,s,Q Qiaia kfaransnsnsn ni niwwatksa ttsts isruruar itasrtP Piuiuk k tsts itsniania net netpopommo iit llillitstststsb oibpopom m m mobrbSo S Sei ei ei ei ae mdododcacacararaziaziruruk.k.a artrt.f caftstsA A k.k.psps nainaisr.rp pueuemmp pununununasaavaA A nnnnysys susuai ai ai aimaulm lirullialalalfr ososos efueueue squq ilist il .it p.spspspbsb bsbusus ssasa nainv aeaeusaismumu soso rubrb muim llu illizrzrzrzricacaahahahahNipisp is is is qilqililo ilobubu bubu usus,s,s b b s sci ciroszonenene oloroyolylyly s ss,s, ,m mrs,s isisairair abab nerebibi a a a aanas sui uitctcnenemmmm AziAciaf cie af cafmamamamsaulsliulsissisisisneineievevaueclicn n neineig g uau irae irririoesusumozi zi a a a a ruerererefmuf hra hra bol bol P Pdodododoqi ueusulqolilqolil lsliulsulsolcliacliulacli a aeiacaB Bgeinig g gnirnir eaevuvummarnu irniurnu iruhi aiteteyhyhhchchchchuhtuhB B as t seaBe ololrB G GarsI asIM Mtete iriririrM MT T T Tymya mymB B B Bhthst t t ssusa aul u l ulsullilcliulsliulsulliulclicliclicacBaBcliacliacaaBaBaBaBB B BPage 47 of 48esa dercreetcnIvoep0 - 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[0069] One aspect disclosed herein is the use of the active compound combinations disclosed herein as a plant-strengthening agent.

[0070] Another aspect is the use of the active compound combinations disclosed herein for treatment of a transgenic plant.

[0071] Another aspect is the use of the active compound combinations disclosed herein for treatment of seed.

[0072] Another aspect disclosed herein is a seed coated with active compound combinations according disclosed herein.

[0073] Disclosed herein are also methods of using the disclosed compositions to control, prevent, combat, or eliminate a pest or a pest infestation. Such methods comprise the step of applying the compositions disclosed herein to a pest, to a locus of a pest, to a place where a pest inhabits, a site of a pest infestation, a plant susceptible to a pest attack, or to a pest’s food supply. In some aspects, disclosed herein is method of applying the compositions disclosed herein to a crop or a plant susceptible to a pest infestation. In some aspects, the method of combating or controlling a pest comprises applying the compositions disclosed herein to the site of infestation.

[0074] The compositions disclosed herein can be applied in a manner known in the agrochemical technology. For example, as the compositions disclosed herein comprise components A and B, they can be applied simultaneously or sequentially. In some aspects, a formulation comprising component A and a formulation comprising component B can be applied simultaneously or sequentially. In some instances, a formulation comprising both A and B can be applied. In these instances, a formulation comprising component A and a formulation comprising component B can be mixed together, and the mixed formulation / mixture can be applied.

[0075] Another aspect disclosed herein is a seed treatment formulation comprising the pesticidal compositions disclosed throughout this specification. In some other aspects, disclosed herein is a plant propagule treated with the disclosed pesticidal compositions. The plant propagule is selected from the group consisting of shoots, branches, seeds, leaves, roots and tubers. In some aspect, the plant propagule is a seed. In some aspect, disclosed herein is a seed coated with a pesticidal composition disclosed herein. “Coating” in this context means applying, dusting, spraying, substantially covering a seed with a composition disclosed herein. “Treating a seed ” and “coating a seed” can be used interchangeably throughout this disclosure. In someother aspects, disclosed herein is a composition comprising pesticidal compositions disclosed throughout this specification and a seed.

[0076] In another aspect, disclosed herein is a use of pesticidial compositions disclosed herein to prevent, combat, eliminate, suppress, or retard a pest, a pest population. Such use comprises the application of the pesticidal composition to the locus where the pest inhabits, site of infestation, a plant or a crop susceptible to a pest attack, a pest food supply or a pest itself.

[0077] In light of the above disclosure, following further details are provided:

[0078] dl. A pesticidal composition comprising:

[0079] A) a compound of Formula One (Fl); and

[0080] B) a biological agent (B) selected from the group consisting of Bacillus species, Baclovirus species, Pseudomonas species, Beauveria species, Mycobacterium species, Mycorrhizal fungi, Trichoderma species, and Metarhizium species.

[0081] d2. The pesticidal composition according dl, further comprising an active compound selected from the group consisting of insecticides, fungicides, and nematicides.

[0082] d3. The pesticidal composition according to d2, wherein the active compound is selected from the group consisting of azoxystrobin, copper hydroxide, difenoconazole, ethaboxam, fludioxonil, fluopyram, fluoxastrobin, fluxapyroxad, inpyrfluxam, ipconazole, isoflucypram, mefenoxam, mefentrifluconazole, metalaxyl, myclobutanil, oxathiapiprolin, picoxystrobin, propi conazole, prothiaconazole, pydiflumetofen, pyroclostrobin, sedaxane, tebuconazole, thiabendazole, thiram, titriconazole and trifloxystrobin.

[0083] d4. The pesticidal composition of d2, wherein the active compound is selected from the group consisting of abamectin, acetamiprid, benzpyrimoxan, bifenthrin, chlorantraniliprole, chlorfenapyr, cyantraniliprole, cyclobutrifluram, dimepropyridaz, fipronil, flonicamid, fluoxapiprolin, flupyradifurone, flupyrimin, fluxametamide, imidacloprid, indoxacarb, isocycloseram, / a Ma-cyhalothrin, methoxyfenozide, pymetrozine, pyriproxyfen, spidoxamat, spinetoram, spinosad, spiropidion, spirotetramat, sulfoxaflor, thiamethoxam, and triflumezopyrim.

[0084] d5. The pesticidal composition according to dl -d4, wherein the Bacillus species is selected from the group consisting of Bacillus thuringiensis, Bacillus amyloliquifaciens, Bacillus subtilis, Bacillus firmus, Bacillus pumilus, Bacillus sphaericus,

[0085] d6. The pesticidal composition according to dl-d5, wherein the Bacillus species isBacillus thuringiensis var. kurstaki, Bacillus thuringiensis var. tenebrionis, or Bacillus thuringiensis var. aizawai.

[0086] d7. The pesticidal composition according to dl-d5, wherein the Bacillus species isBacillus amyloliquifaciens var. PTA4838.

[0087] d8. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) cyclobutrifluram.

[0088] d9. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) isocycloseram.

[0089] dlO. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) ipconazole.

[0090] dl l. The pesticidal composition according d2, comprising A) F 1 ; B) Bacillus thuringiensis sp. and C) clothianidin.

[0091] dl2. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) inpyrfluxam.

[0092] dl 3. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) ethaboxam.

[0093] dl4. The pesticidal composition according d2, comprising A) Fl; B) Bacillus thuringiensis sp. and C) metalaxyl.

[0094] dl 5. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) cyclobutrifluram.

[0095] dl 6. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens. and C) isocycloseram.

[0096] dl7. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) ipconazole.

[0097] dl 8. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) clothianidin.

[0098] dl 9. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) inpyrfluxam.

[0099] d20. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) ethaboxam.

[0100] d21. The pesticidal composition according d2, comprising A) Fl; B) Bacillus amyloliquifaciens sp. and C) metalaxyl.

[0101] d22. The pesticidal composition according to dl-d5, d7, dl 5-d21 , wherein Bacillus amyloliquifaciens sp. is Bacillus amyloliquifaciens PTA 4838 or Bacillus amyloliquifaciens MBI 600.

[0102] d23. The pesticidal composition according to dl-d22, wherein ratio of A) Fl, to B) biological agent, is 1 :1 to 1 : 10000, preferably from 1 : 1 to 1:2000, preferably from 1 : 1 to 1: 1000, and more preferably from 1 : 1 to 1:500.

[0103] d24. A method of controlling or combating a pest infestation comprising applying the composition according to any of dl -d23 to the locus of the pest infestation.

[0104] d25. A method of controlling and / or combating a pest comprising applying the composition according to any of dl -d23 to a pest, to a locus of a pest, a plant susceptible to attack by a pest, sites where pest inhabits, or food supply of a pest.

[0105] d26. The method according to any of d24-d25, comprising mixing a formulation comprising A and a formulation comprising B, and applying the combined formulation according to method d25-d26.

[0106] d27. The method according to any of d24-d26, wherein components A and B are applied in a sequential manner in any order.

[0107] d28. The method according to any of d24-d26, wherein components A and B are applied simultaneously.

[0108] d29. The method according to any of d24-d28, wherein the pest is from theLepidoptera order and / or from the Coleoptera order.

[0109] d30. The method according to any of d24-d28, wherein the plant is selected from the group consisting of cereals, leguminous crops, fiber plants and vegetables.

[0110] d31. A use of the pesticidal composition according to any of d 1 -d23 to control and / or combat the pests from Lepidoptera order and / or from the Coleoptera order.

[0111] d32. A composition comprising a plant propagation material and the pesticidal composition according to any of dl -d23.

[0112] d33. The composition according d32, wherein the plant propagation material is a seed.

[0113] d34. A method of using the composition according to any of dl-d23 comprising providing the composition by coating a seed with the composition or by applying the composition in conjunction with the seeds, or prior to, or after the time of seeding.

[0114] d35. A seed coated with the composition according to any of dl-d23.

[0115] d36. A seed treatment composition comprising the composition according to any of dl-d24.

[0116] Following further details are related to the compound of Formula Two (F2):

[0117] d37. A pesticidal composition comprising:

[0118] A) a compound of Formula Two (F2); and

[0119] B) a biological agent (B) selected from the group consisting of Bacillus species, Baclovirus species, Pseudomonas species, Beauveria species, Mycobacterium species, Mycorrhizal fungi, Trichoderma species, and Metarhizium species.

[0120] d38. The pesticidal composition according d37, further comprising an active compound selected from the group consisting of insecticides, fungicides, and nematicides.

[0121] d39. The pesticidal composition according to d38, wherein the active compound is selected from the group consisting of azoxystrobin, copper hydroxide, difenoconazole, ethaboxam, fludioxonil, fluopyram, fluoxastrobin, fluxapyroxad, inpyrfluxam, ipconazole, isoflucypram, mefenoxam, mefentrifluconazole, metalaxyl, myclobutanil, oxathiapiprolin, picoxystrobin, propi conazole, prothiaconazole, pydiflumetofen, pyroclostrobin, sedaxane, tebuconazole, thiabendazole, thiram, titriconazole and trifloxystrobin.

[0122] d40. The pesticidal composition of d38, wherein the active compound is selected from the group consisting of abamectin, acetamiprid, benzpyrimoxan, bifenthrin, chlorantraniliprole, chlorfenapyr, cyantraniliprole, cyclobutrifluram, dimepropyridaz, fipronil, flonicamid, fluoxapiprolin, flupyradifurone, flupyrimin, fluxametamide, imidacloprid, indoxacarb, isocycloseram, / a Mcz-cyhalothrin, methoxyfenozide, pymetrozine, pyriproxyfen, spidoxamat, spinetoram, spinosad, spiropidion, spirotetramat, sulfoxaflor, thiamethoxam, and triflumezopyrim.

[0123] d41. The pesticidal composition according to d37-d40, wherein the Bacillus species is selected from the group consisting of Bacillus thuringiensis, Bacillus amyloliquifaciens, Bacillus subtilis, Bacillus firmus, Bacillus pumilus, and Bacillus sphaericus,

[0124] d42. The pesticidal composition according to d37-d40, wherein the Bacillus species is Bacillus thuringiensis var. kurstaki, Bacillus thuringiensis var. tenebrionis, or Bacillus thuringiensis var. aizawai.

[0125] d43. The pesticidal composition according to d37-d40, wherein the Bacillus species is Bacillus amyloliquifaciens var. PTA4838.

[0126] d44. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) cyclobutrifluram.

[0127] d45. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) isocycloseram.

[0128] d46. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) ipconazole.

[0129] d47. The pesticidal composition according d38 comprising A) F2; B) Bacillus thuringiensis sp. and C) clothianidin.

[0130] d48. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) inpyrfluxam.

[0131] d49. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) ethaboxam.

[0132] d50. The pesticidal composition according d38, comprising A) F2; B) Bacillus thuringiensis sp. and C) metalaxyl.

[0133] d51. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp. and C) cyclobutrifluram.

[0134] d52. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens. and C) isocycloseram.

[0135] d53. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp.and C) ipconazole.

[0136] d54. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp.and C) clothianidin.

[0137] d55. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp. and C) inpyrfluxam.

[0138] d56. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp. and C) ethaboxam.

[0139] d57. The pesticidal composition according d38, comprising A) F2; B) Bacillus amyloliquifaciens sp. and C) metalaxyl.

[0140] d58. The pesticidal composition according to d37-d41, , d51 -d57, wherein Bacillus amyloliquifaciens sp. is Bacillus amyloliquifaciens PTA 4838 or Bacillus amyloliquifaciens MBI 600.

[0141] d59. The pesticidal composition according to d37-d58, wherein ratio of A) F2, to B) biological agent, is 1 :1 to 1 : 10000, preferably from 1 : 1 to 1:2000, preferably from 1 : 1 to 1: 1000, and more preferably from 1 : 1 to 1:500.

[0142] d60. A method of controlling or combating a pest infestation comprising applying the composition according to any of d37-d59 to the locus of the pest infestation.

[0143] d61. A method of controlling and / or combating a pest comprising applying the composition according to any of d37-d59 to a pest, to a locus of a pest, a plant susceptible to attach by a pest, sites where pest inhabits, or food supply of a pest.

[0144] d62. The method according to any of d60-d61, comprising mixing a formulation comprising A and a formulation comprising B, and applying the combined formulation according to method d60-d61.

[0145] d63. The method according to any of d60-d62, wherein components A and B are applied in a sequential manner in any order.

[0146] d64. The method according to any of d60-d62, wherein components A and B are applied simultaneously.

[0147] d65. The method according to any of d60-d64, wherein the pest is from theLepidoptera order and / or from the Coleoptera order.

[0148] d66. The method according to any of d60-d64, wherein the plant is selected from the group consisting of cereals, leguminous crops, fiber plants and vegetables.

[0149] d67. A use of the pesticidal composition according to any of d37-d59 to control and / or combat the pests from Lepidoptera order and / or from the Coleoptera order.

[0150] d68. A composition comprising a plant propagation material and the pesticidal composition according to any of d37-d59.

[0151] d69. The composition according to d68, wherein the plant propagation material is a seed.

[0152] d70. A method of using the composition according to any of d37-d59 comprising providing the composition by coating a seed with the composition or by applying the composition in conjunction with the seeds, or prior to, or after the time of seeding.

[0153] d71. A seed coated with the composition according to any of d37-d59.

[0154] d73. A seed treatment composition comprising the composition according to any of d38-d61.BIOLOGICAL ASSAYS

[0155] The following bioassays were conducted against sweet potato whitefly (Bemisia tabaci), fall armyworm (Spodoptera frugiperdd), diamondback moth (Plutella xylostella), beet army worm (Spodoptera exigud), tobacco cutworm (Spodoptera litura), and Western com rootworm (Diabrotica virgifera virgiferd) which are good indicator species for a broad global range of agricultural pests for many agriculturally important plant species. The results with these indicator species show the broad usefulness of various pesticides (also referred to as active ingredients) mixed with molecules of Formula One in controlling pest insects.

[0156] Bioassay 1: Fall Armyworm (FAW, Spodoptera frugiperda), Diamondback Moth (DBM, Plutella xylostella), and Beet Armyworm (BAW, Spodoptera exigua).

[0157] This series of bioassays was conducted against three key lepidopteran pests: fall armyworm (FAW), diamondback moth (DBM), and beet armyworm (BAW). These species serve as reliable indicator organisms for evaluating the efficacy of insecticides across a broad spectrum of agricultural pests. The results obtained from these bioassays demonstrate the broadspectrum potential of various active ingredients, particularly when formulated with molecules from Formula One, in effectively controlling these economically significant insect pests.

[0158] Formula One (Fl) testing solutions were prepared at concentrations of 0.0003, 0.0009, 0.0018, and 0.0036 pg active ingredient (ugai) per 20 pL for each species. The concentrations of the active ingredient varied depending on the specific material tested.

[0159] The following procedure describes the test method. An artificial lepidopteran diet (Multispecies Lepidopteran Diet, Southland Products) was dispensed into 96-well plates. Each well received 20 pL of the test solution, evenly covering the diet surface. A water-only control (diluent check) was included on each plate for reference. Each treatment was replicated 5-6 times per species. After the surface dried, 5 - 6 first instar larva was placed in each well andcovered with a clear, perforated lid. Test trays were held at approximately 26°C and ambient relative humidity until evaluation. Larval survival was assessed after 5 days for BAW, and after 7 days for FAW and DBM. The percentage of pest control was calculated using Abbott’s correction formula (W. S. Abbott, J. Econ. Entomol. 18, 1925, pp. 265-267):

[0160] Corrected % Control = (l-(Y / X))*100

[0161] where X = No. of live larvae on solvent check and Y = No. of live larvae on treated diet. In Table B4 the “Expected % Control” was calculated using the method described in Colby S. R., Weeds, 1967, 15, 20-22. The results are shown in Table 1 below.

[0162] Bioassay 2: Fall armyworm (FAW, Spodoptera frugiperda), and Tobacco Cutworm (TCW, Spodoptera litura).

[0163] This set of bioassays targeted fall armyworm (FAW) and tobacco cutworm (TCW), two important lepidopteran pests that serve as effective indicator species for evaluating insecticide performance across a wide range of agricultural pests. The results highlight the broadspectrum efficacy of various active ingredients, particularly when combined with molecules from Formula One, in controlling these and potentially other pest species.

[0164] Fl testing solutions concentrations for FAW and TCW ranged from 0.002 - 0.032 ugai / 20uL. The active ingredient test solution concentration was 50 ugai / well. The following procedure describes the test method. An artificial lepidopteran diet (Multispecies Lepidopteran Diet, Southland Products) was distributed in 128-cell white plastic bioassay tray and air dried. 30 pL of test solution was pipetted onto the well; covering the diet surface. A reference diluent water only check was present. Each treatment was replicated 32 times for each species. After the surface dried one second instar larva was placed on top of the diet in each cell and covered with a clear perforated lid. Test trays were held at approximately 25-26 °C and ambient relative humidity prior to grading. After three and five days, the number of live larvae were recorded from each cell and percent control was measured using Abbott’s correction formula. (W. S.Abbott, J. Econ. Entomol. 18 (1925), pp. 265-267) as follows:

[0165] Corrected % Control = (l-(Y / X))*100

[0166] where X = No. of live larvae on solvent check and Y = No. of live larvae on treated diet.

[0167] In Table 2 the five day evaluation of the “Expected % Control” was calculated using the method described in Colby S. R., Weeds, 1967, 15, 20-22.

[0168] Bioassay 3 and 4 : Western Corn Rootworm (WCR, Diabrotica virgifera virgifera)

[0169] The western corn rootworm (WCR) is one of the most economically damaging beetle pests (Order: Coleoptera) in North America and Europe. It attacks corn roots annually, with larval feeding early in the season impairing plant development and compromising structural integrity. This damage often results in reduced yields and plant lodging. WCR serves as a representative model for evaluating control measures against soil-dwelling pests that target plant root systems and seeds.The following procedure outlines the WCR diet-based bioassay method. An artificial diet (based on an internal Corteva Agriscience-Pioneer formulation) was dispensed into the wells of a 96-well plate and allowed to dry. Each well then received 30 pL of test solution, evenly covering the diet surface. A reference control (diluent only) was included on each plate. Each treatment was replicated five times. Once the surface dried, 5-7 first-instar larvae were placed in each well and covered with a clear perforated lid. The test trays were maintained at approximately 26 °C and ambient relative humidity until evaluation. After five days, the number of wells with live larvae were recorded, and percent control was calculated using Abbot’s correction formula. (W. S. Abbott, J. Econ. Entomol. 18 (1925), pp. 265-267) as follows:

[0170] Corrected % Control = (l-(Y / X))*100

[0171] where X = No. of wells with live larvae on solvent check and Y = No. of wells with live larvae on treated diet. The results are shown in Table 3 below.

[0172] A soil-based bioassay was also conducted to evaluate the efficacy of test solutions against western corn rootworm (WCR). Corn seeds were placed at the bottom of holes in pots filled with steam-pasteurized soil, and 100 pL of the test solution was applied directly over each seed. The Fl testing solution concentration for WCR resulted in 125 pgai being deposited over the seed. WCR eggs, suspended in a 0.08% agar solution, were introduced into four evenly spaced holes surrounding the seed placement site. The plants were then grown in a greenhouse at 25 °C for 13 days. After the growth period, roots were carefully removed from the soil, washed, and dried for biomass analysis. Dry root weights were recorded and compared to both infested and un-infested untreated controls. The mean percent control provided by each test solution was calculated using the following formula:

[0173] Percent Control = 100 ((A- B) / (C-B)).

[0174] Equation 1. Percent Control: A (the infested test material); B (infested untreated check); and C (un-infested untreated check) plant. The results are indicated in Table 4 below.

[0175] Bioassay 5 : Sweet Potato Whitefly (SPW, Bemisia tabaci).

[0176] The sweet potato whitefly (Bemisia tabaci), commonly referred to as SPW, is a serious pest that poses a significant threat to cotton production. In addition to cotton, SPW affects a wide range of vegetable crops — including melons, cole crops, tomatoes, and head lettuce — as well as various ornamental plants. SPW inflicts damage through two primary mechanisms: direct feeding and virus transmission. As a sap-feeding insect, SPW extracts vital nutrients from plant tissues, leading to symptoms such as stunted growth, defoliation, reduced yields, and boll shed in cotton. Furthermore, SPW excretes large amounts of honeydew, which promotes the growth of sooty mold on foliage, impairing photosynthesis and overall plant health. Beyond physical damage, SPW serves as a vector for several plant viruses, including cotton leaf crumple virus and tomato yellow leaf curl virus, compounding its impact on crop productivity and quality.

[0177] Stock solutions were prepared using d-water as a diluent for Formula One (Fl) as well as for each of the active ingredients individually. All stock solutions were prepared at twice the targeted concentration needed for testing. Stock solutions were further diluted at a 1 : 1 ratio with the addition of water, or the other Stock solution of the active ingredients to obtain Test solution concentrations and mixtures presented in the Tables 5 below.

[0178] When Bemisia tabaci were present at the crawler stage on infested cotton plants grown in pots, test solutions were applied to five plants using a turntable sprayer calibrated to deliver 1,000 L / ha. Following treatment, the plants were maintained in a controlled environment room at approximately 25°C with ambient relative humidity until evaluation. Nine days posttreatment, efficacy was assessed by counting the number of developed third to fourth instar nymphs per plant under a microscope. Percent control was measured based on the untreated check using Abbott’s correction formula (W. S. Abbott, J. Econ. Entomol. 18 (1925), pp. 265— 267) as follows:

[0179] Corrected % Control = (l-(Y / X))*100

[0180] where X = No. of live nymphs on solvent check plants and Y = No. of live nymphs on treated plants. In Table 5 the “Expected % Control” was calculated using the method described in Colby S. R., Weeds, 1967, 15, 20-22.

[0181] Formulations

[0182] A pesticide may not be suitable for application in its pure form. It is usually necessary to add other substances so that the pesticide may be used at the required concentration and in an appropriate form, permitting ease of application, handling, transportation, storage, and maximum pesticide activity. Thus, pesticides are formulated into, for example, baits, concentrated emulsions, dusts, emulsifiable concentrates, fumigants, gels, granules, microencapsulations, seed treatments, suspension concentrates, suspoemulsions, tablets, water soluble liquids, water dispersible granules, dry flowables, wettable powders, or ultra-low volume solutions.

[0183] Pesticides are applied most often as aqueous suspensions or emulsions prepared from concentrated formulations of such pesticides. Such water-soluble, water-suspendable, or emulsifiable formulations are either solids, usually known as wettable powders, water dispersible granules, liquids usually known as emulsifiable concentrates, or aqueous suspensions. Wettable powders, which may be compacted to form water dispersible granules, comprise an intimate mixture of the pesticide, a carrier, and surfactants. The concentration of the pesticide is usually from about 10% to about 90% by weight. The carrier is usually selected from among the attapulgite clays, the montmorillonite clays, the diatomaceous earths, or the purified silicates. Effective surfactants, comprising from about 0.5% to about 10% of the wettable powder, are found among sulfonated lignins, condensed naphthalenesulfonates, naphthalenesulfonates, alkylbenzenesulfonates, alkyl sulfates, and non-ionic surfactants such as ethylene oxide adducts of alkyl phenols.

[0184] Emulsifiable concentrates of pesticides comprise a convenient concentration of a pesticide, such as from about 50 to about 500 grams per liter of liquid dissolved in a carrier that is either a water miscible solvent or a mixture of water-immiscible organic solvent and emulsifiers. Useful organic solvents include aromatics, especially xylenes and petroleum fractions, especially the high-boiling naphthalenic and olefinic portions of petroleum such as heavy aromatic naphtha. Other organic solvents may also be used, such as the terpenic solvents including rosin derivatives, aliphatic ketones such as cyclohexanone, and complex alcohols such as 2-ethoxy ethanol. Suitable emulsifiers for emulsifiable concentrates are selected from conventional anionic and non-ionic surfactants.

[0185] Aqueous suspensions comprise suspensions of water-insoluble pesticides dispersed in an aqueous carrier at a concentration in the range from about 5% to about 50% by weight.Suspensions are prepared by finely grinding the pesticide and vigorously mixing it into a carrier comprised of water and surfactants. Ingredients, such as inorganic salts and synthetic or natural gums may, also be added to increase the density and viscosity of the aqueous carrier. It is often most effective to grind and mix the pesticide at the same time by preparing the aqueous mixture and homogenizing it in an implement such as a sand mill, ball mill, or piston-type homogenizer. The pesticide in suspension might be microencapsulated in plastic polymer.

[0186] Oil dispersions (OD) comprise suspensions of organic solvent-insoluble pesticides finely dispersed in a mixture of organic solvent and emulsifiers at a concentration in the range from about 2% to about 50% by weight. One or more pesticides might be dissolved in the organic solvent. Useful organic solvents include aromatics, especially xylenes and petroleum fractions, especially the high-boiling naphthalenic and olefinic portions of petroleum such as heavy aromatic naphtha. Other solvents may include vegetable oils, seed oils, and esters of vegetable and seed oils. Suitable emulsifiers for oil dispersions are selected from conventional anionic and non-ionic surfactants. Thickeners or gelling agents are added in the formulation of oil dispersions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets.

[0187] Pesticides may also be applied as granular compositions that are particularly useful for applications to the soil. Granular compositions usually contain from about 0.5% to about 10% by weight of the pesticide, dispersed in a carrier that comprises clay or a similar substance. Such compositions are usually prepared by dissolving the pesticide in a suitable solvent and applying it to a granular carrier, which has been pre-formed to the appropriate particle size, in the range of from about 0.5 mm to about 3 mm. Such compositions may also be formulated by making a dough or paste of the carrier and molecule, and then crushing and drying to obtain the desired granular particle size. Another form of granules is a water emulsifiable granule (EG). It is a formulation consisting of granules to be applied as a conventional oil-in-water emulsion of the active ingredient(s), either solubilized or diluted in an organic solvent, after disintegration and dissolution in water. Water emulsifiable granules comprise one or several active ingredient(s), either solubilized or diluted in a suitable organic solvent that is (are) absorbed in a water-soluble polymeric shell or some other type of soluble or insoluble matrix.

[0188] Dusts containing a pesticide are prepared by intimately mixing the pesticide in powdered form with a suitable dusty agricultural carrier, such as kaolin clay, ground volcanicrock, and the like. Dusts can suitably contain from about 1% to about 10% of the pesticide. Dusts may be applied as a seed dressing or as a foliage application with a dust blower machine.

[0189] It is equally practical to apply a pesticide in the form of a solution in an appropriate organic solvent, usually petroleum oil, such as the spray oils, which are widely used in agricultural chemistry.

[0190] Pesticides can also be applied in the form of an aerosol composition. In such compositions, the pesticide is dissolved or dispersed in a carrier, which is a pressure-generating propellant mixture. The aerosol composition is packaged in a container from which the mixture is dispensed through an atomizing valve.

[0191] Pesticide baits are formed when the pesticide is mixed with food or an attractant or both. When the pests eat the bait, they also consume the pesticide. Baits may take the form of granules, gels, flowable powders, liquids, or solids. Baits may be used in pest harborages.

[0192] Fumigants are pesticides that have a relatively high vapor pressure and hence can exist as a gas in sufficient concentrations to kill pests in soil or enclosed spaces. The toxicity of the fumigant is proportional to its concentration and the exposure time. They are characterized by a good capacity for diffusion and act by penetrating the pest’ s respiratory system or being absorbed through the pest’s cuticle. Fumigants are applied to control stored product pests under gas proof sheets, in gas sealed rooms or buildings, or in special chambers.

[0193] Pesticides may be microencapsulated by suspending the pesticide particles or droplets in plastic polymers of various types. By altering the chemistry of the polymer or by changing factors in the processing, microcapsules may be formed of various sizes, solubility, wall thicknesses, and degrees of penetrability. These factors govern the speed with which the active ingredient within is released, which in turn, affects the residual performance, speed of action, and odor of the product. The microcapsules might be formulated as suspension concentrates or water dispersible granules.

[0194] Oil solution concentrates are made by dissolving pesticide in a solvent that will hold the pesticide in solution. Oil solutions of a pesticide usually provide faster knockdown and kill of pests than other formulations due to the solvents themselves having pesticidal action and the dissolution of the waxy covering of the integument increasing the speed of uptake of the pesticide. Other advantages of oil solutions include better storage stability, better penetration of crevices, and better adhesion to greasy surfaces.

[0195] Another embodiment is an oil-in-water emulsion, wherein the emulsion comprises oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase, wherein each oily globule comprises at least one molecule which is agriculturally active, and is individually coated with a monolamellar or oligolamellar layer comprising: (1) at least one non-ionic lipophilic surface-active agent, (2) at least one non-ionic hydrophilic surface-active agent, and (3) at least one ionic surface-active agent, wherein the globules having a mean particle diameter of less than 800 nanometers.

[0196] Other Formulation Components

[0197] Generally, when the compositions disclosed herein are used in a formulation, such formulation can also contain other components. These components include, but are not limited to, (this is a non-exhaustive and non-mutually exclusive list) wetters, spreaders, stickers, penetrants, buffers, sequestering agents, drift reduction agents, compatibility agents, anti-foam agents, cleaning agents, and emulsifiers. A few components are described forthwith.

[0198] A wetting agent is a substance that when added to a liquid increases the spreading or penetration power of the liquid by reducing the interfacial tension between the liquid and the surface on which it is spreading. Wetting agents are used for two main functions in agrochemical formulations: during processing and manufacture to increase the rate of wetting of powders in water to make concentrates for soluble liquids or suspension concentrates; and during mixing of a product with water in a spray tank to reduce the wetting time of wettable powders and to improve the penetration of water into water-dispersible granules. Examples of wetting agents used in wettable powder, suspension concentrate, and water-dispersible granule formulations are sodium lauryl sulfate, sodium dioctyl sulfosuccinate, alkyl phenol ethoxylates, and aliphatic alcohol ethoxylates.

[0199] A dispersing agent is a substance that adsorbs onto the surface of particles, helps to preserve the state of dispersion of the particles, and prevents them from reaggregating. Dispersing agents are added to agrochemical formulations to facilitate dispersion and suspension during manufacture, and to ensure the particles redisperse into water in a spray tank. They are widely used in wettable powders, suspension concentrates, and water-dispersible granules. Surfactants that are used as dispersing agents have the ability to adsorb strongly onto a particle surface and provide a charged or steric barrier to reaggregation of particles. The most commonly used surfactants are anionic, non-ionic, or mixtures of the two types. For wettable powderformulations, the most common dispersing agents are sodium lignosulfonates. For suspension concentrates, very good adsorption and stabilization are obtained using polyelectrolytes, such as sodium-naphthalene-sulfonate-formaldehyde-condensates. Tristyrylphenol ethoxylate phosphate esters are also used. Non-ionics such as alkylarylethylene oxide condensates and EO- PO block copolymers are sometimes combined with anionics as dispersing agents for suspension concentrates. In recent years, new types of very high molecular weight polymeric surfactants have been developed as dispersing agents. These have very long hydrophobic ‘backbones’ and a large number of ethylene oxide chains forming the ‘teeth’ of a ‘comb’ surfactant. These high molecular weight polymers can give very good long-term stability to suspension concentrates because the hydrophobic backbones have many anchoring points onto the particle surfaces. Examples of dispersing agents used in agrochemical formulations are: sodium lignosulfonates, sodium naphthalene sulfonate formaldehyde condensates, tristyrylphenol-ethoxylate-phosphate- esters, aliphatic alcohol ethoxylates, alkyl ethoxylates, EO-PO block copolymers, and graft copolymers.

[0200] An emulsifying agent is a substance that stabilizes a suspension of droplets of one liquid phase in another liquid phase. Without the emulsifying agent, the two liquids would separate into two immiscible liquid phases. The most commonly used emulsifier blends contain an alkylphenol or an aliphatic alcohol with twelve or more ethylene oxide units and the oilsoluble calcium salt of dodecylbenzenesulfonic acid. A range of hydrophile— lipophile balance (“HLB”) values from about 8 to about 18 will normally provide good, stable emulsions. Emulsion stability can sometimes be improved by the addition of a small amount of an EO-PO block copolymer surfactant.

[0201] A solubilizing agent is a surfactant that will form micelles in water at concentrations above the critical micelle concentration. The micelles are then able to dissolve or solubilize water-insoluble materials inside the hydrophobic part of the micelle. The types of surfactants usually used for solubilization are non-ionics, sorbitan monooleates, sorbitan monooleate ethoxylates, and methyl oleate esters.

[0202] Surfactants are sometimes used, either alone or with other additives such as mineral or vegetable oils as adjuvants to spray-tank mixes to improve the biological performance of the pesticide on the target. The types of surfactants used for bioenhancement depend generally onthe nature and mode of action of the pesticide. However, they are often non-ionics such as: alkyl ethoxylates, linear aliphatic alcohol ethoxylates, and aliphatic amine ethoxylates.

[0203] A carrier or diluent in an agricultural formulation is a material added to the pesticide to give a product of the required strength. Carriers are usually materials with high absorptive capacities, while diluents are usually materials with low absorptive capacities. Carriers and diluents are used in the formulation of dusts, wettable powders, granules, and water-dispersible granules.

[0204] Organic solvents are used mainly in the formulation of emulsifiable concentrates, oil- in-water emulsions, suspoemulsions, oil dispersions, and ultra-low volume formulations, and to a lesser extent, granular formulations. Sometimes mixtures of solvents are used. The first main groups of solvents are aliphatic paraffinic oils such as kerosene or refined paraffins. The second main group (and the most common) comprises the aromatic solvents such as xylene and higher molecular weight fractions of C9 and CIO aromatic solvents. Chlorinated hydrocarbons are useful as cosolvents to prevent crystallization of pesticides when the formulation is emulsified into water. Alcohols are sometimes used as cosolvents to increase solvent power. Other solvents may include vegetable oils, seed oils, and esters of vegetable and seed oils.

[0205] Thickeners or gelling agents are used mainly in the formulation of suspension concentrates, oil dispersions, emulsions and suspoemulsions to modify the rheology or flow properties of the liquid and to prevent separation and settling of the dispersed particles or droplets. Thickening, gelling, and anti-settling agents generally fall into two categories, namely water-insoluble particulates and water-soluble polymers. It is possible to produce suspension concentrate and oil dispersion formulations using clays and silicas. Examples of these types of materials, include, but are not limited to, montmorillonite, bentonite, magnesium aluminum silicate, and attapulgite. Water-soluble polysaccharides in water-based suspension concentrates have been used as thickening-gelling agents for many years. The types of polysaccharides most commonly used are natural extracts of seeds and seaweeds or are synthetic derivatives of cellulose. Examples of these types of materials include, but are not limited to, guar gum, locust bean gum, carrageenam, alginates, methyl cellulose, sodium carboxymethyl cellulose (SCMC), and hydroxyethyl cellulose (HEC). Other types of anti-settling agents are based on modified starches, polyacrylates, polyvinyl alcohol, and polyethylene oxide. Another good anti-settling agent is xanthan gum.

[0206] Microorganisms can cause spoilage of formulated products. Therefore, preservation agents are used to eliminate or reduce their effect. Examples of such agents include, but are not limited to: propionic acid and its sodium salt, sorbic acid and its sodium or potassium salts, benzoic acid and its sodium salt, -hydroxybenzoic acid sodium salt, methyl p- hydroxybenzoate, and l,2-benzisothiazolin-3-one (BIT).

[0207] The presence of surfactants often causes water-based formulations to foam during mixing operations in production and in application through a spray tank. In order to reduce the tendency to foam, anti-foam agents are often added either during the production stage or before filling into bottles. Generally, there are two types of anti-foam agents, namely silicones and non-silicones. Silicones are usually aqueous emulsions of dimethyl polysiloxane, while the nonsilicone anti-foam agents are water-insoluble oils, such as octanol and nonanol, or silica. In both cases, the function of the anti-foam agent is to displace the surfactant from the air-water interface.

[0208] “Green” agents (e.g., adjuvants, surfactants, solvents) can reduce the overall environmental footprint of crop protection formulations. Green agents are biodegradable and generally derived from natural and / or sustainable sources, e.g. plant and animal sources. Specific examples are: vegetable oils, seed oils, and esters thereof, also alkoxylated alkyl polyglucosides.

[0209] Applications

[0210] Compositions disclosed herein may be applied to any locus. Particular loci to apply such molecules include loci where alfalfa, almonds, apples, barley, beans, canola, com, cotton, crucifers, flowers, fodder species (Rye Grass, Sudan Grass, Tall Fescue, Kentucky Blue Grass, and Clover), fruits, lettuce, oats, oil seed crops, oranges, peanuts, pears, peppers, potatoes, rice, sorghum, soybeans, strawberries, sugarcane, sugarbeets, sunflowers, tobacco, tomatoes, wheat (for example, Hard Red Winter Wheat, Soft Red Winter Wheat, White Winter Wheat, Hard Red Spring Wheat, and Durum Spring Wheat), and other valuable crops are growing or the seeds thereof are going to be planted.

[0211] Compositions disclosed herein may also be applied where plants, such as crops, are growing and where there are low levels (even no actual presence) of pests that can commercially damage such plants. Applying such molecules in such locus is to benefit the plants being grown in such locus. Such benefits, may include, but are not limited to: helping the plant grow a better root system; helping the plant better withstand stressful growing conditions; improving the healthof a plant; improving the yield of a plant (e.g. increased biomass and / or increased content of valuable ingredients); improving the vigor of a plant (e.g. improved plant growth and / or greener leaves); improving the quality of a plant e.g. improved content or composition of certain ingredients); and improving the tolerance to abiotic and / or biotic stress of the plant.

[0212] Compositions disclosed herein may be applied with ammonium sulfate when growing various plants as this may provide additional benefits.

[0213] Compositions disclosed herein may be applied on, in, or around plants genetically modified to express specialized traits, such as Bacillus thuringiensis (for example, Cry 1 Ab, Cry 1 Ac, CrylFa, Cry 1 A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Abl / Cry35Abl), other insecticidal toxins, or those expressing herbicide tolerance, or those with “stacked” foreign genes expressing insecticidal toxins, herbicide tolerance, nutritionenhancement, or any other beneficial traits.

[0214] Compositions disclosed herein may be applied to the foliar and / or fruiting portions of plants to control pests. Either such molecules will come in direct contact with the pest, or the pest will consume such molecules when eating the plant or while extracting sap or other nutrients from the plant.

[0215] Compositions disclosed herein may also be applied to the soil, and when applied in this manner, root and stem feeding pests may be controlled. The roots may absorb such molecules thereby taking it up into the foliar portions of the plant to control above ground chewing and sap feeding pests.

[0216] Systemic movement of pesticides in plants may be utilized to control pests on one portion of the plant by applying (for example by spraying a locus) a molecule of Formula One to a different portion of the plant. For example, control of foliar-feeding insects may be achieved by drip irrigation or furrow application, by treating the soil with for example pre- or postplanting soil drench, or by treating the seeds of a plant before planting.

[0217] Compositions disclosed herein may be used with baits. Generally, with baits, the baits are placed in the ground where, for example, termites can come into contact with, and / or be attracted to, the bait. Baits can also be applied to a surface of a building, (horizontal, vertical, or slant surface) where, for example, ants, termites, cockroaches, and flies, can come into contact with, and / or be attracted to, the bait.

[0218] Compositions disclosed herein may be encapsulated inside or placed on the surface of a capsule. The size of the capsules can range from nanometer size (about 100-900 nanometers in diameter) to micrometer size (about 10-900 microns in diameter).

[0219] Compositions disclosed herein may be applied to eggs of pests. Because of the unique ability of the eggs of some pests to resist certain pesticides, repeated applications of such molecules may be desirable to control newly emerged larvae.

[0220] Compositions disclosed herein may be applied as seed treatments. Seed treatments may be applied to all types of seeds, including those from which plants genetically modified to express specialized traits will germinate. Representative examples include those expressing proteins toxic to invertebrate pests, such as Bacillus thuringiensis or other insecticidal toxins, those expressing herbicide tolerance, such as “Roundup Ready” seed, or those with “stacked” foreign genes expressing insecticidal toxins, herbicide tolerance, nutrition-enhancement, drought tolerance, or any other beneficial traits. Furthermore, such seed treatments with molecules of Formula One may further enhance the ability of a plant to withstand stressful growing conditions better. This results in a healthier, more vigorous plant, which can lead to higher yields at harvest time. Generally, about 1 gram of such molecules to about 500 grams per 100,000 seeds is expected to provide good benefits, amounts from about 10 grams to about 100 grams per 100,000 seeds is expected to provide better benefits, and amounts from about 25 grams to about 75 grams per 100,000 seeds is expected to provide even better benefits.

[0221] Component A (molecules of Formula One) is present in a pesticidally-effective amount in a formulation for a seed treatment, for example, in an amount of 1% to about 60% by weight, based on the total weight of the seed treatment mixture. Each compound of component B and C are present in a pesticidally-effective amount from about 1% about 60% weight, based on the total weight of the seed treatment mixture. Components A, B and C may be applied to the seed sequentially or simultaneously.

[0222] The seed treatment may include more than one active compound as component B such as compounds having further fungicidal, insecticidal, acaricidal and / or nematocidal properties. As used herein, the term “seed” means any resting stage of a plant that is physically detached from the vegetative state of a plant, and / or may be stored for a prolonged periods of time and / or can be used to regrow another individual plant of the same species. The term “resting” refers to a state where the plant retains viability, within reasonable limits, despite theabsence of light, water and / or nutrients essential for the vegetative (i.e., non-seed) state. In particular for the embodiments, the term refers to true seeds.

[0223] Compositions disclosed herein may be applied with one or more active ingredients in a soil amendment.

[0224] Compositions disclosed herein may be used for controlling endoparasites and ectoparasites in the veterinary medicine sector or in the field of non-human-animal keeping. Such molecules may be applied by oral administration in the form of, for example, tablets, capsules, drinks, granules, by dermal application in the form of, for example, dipping, spraying, pouring on, spotting on, and dusting, and by parenteral administration in the form of, for example, an injection.

[0225] Compositions disclosed herein may also be employed advantageously in livestock keeping, for example, cattle, chickens, geese, goats, pigs, sheep, and turkeys. They may also be employed advantageously in pets such as, horses, dogs, and cats. Particular pests to control would be flies, fleas, and ticks that are bothersome to such animals. Suitable formulations are administered orally to the animals with the drinking water or feed. The dosages and formulations that are suitable depend on the species.

[0226] Compositions disclosed herein may also be used for controlling parasitic worms, especially of the intestine, in the animals listed above.

[0227] Compositions disclosed herein may also be employed in therapeutic methods for human health care. Such methods include, but are limited to, oral administration in the form of, for example, tablets, capsules, drinks, granules, and by dermal application.

[0228] Compositions disclosed herein may also be applied to invasive pests. Pests around the world have been migrating to new environments (for such pests) and thereafter becoming a new invasive species in such new environment. Such molecules may also be used on such new invasive species to control them in such new environments.TABLE 1 - BAWTABLE 1 - BAW (continued)* Ccilc:ulati i f p :-:sih!,TABLE 1 - DBMru:>t possible.TABLE 1 - DBM (continued)TABLE 1 - FAW* C a leu lai possible.TABLE 1 - FAW (continued)* CcilGiikiticn notTABLE 2 - FAWandTCWTABLE 3 - CRWalculaUQYi Kui pcTABLE 3 - CRW (continued)TABLE 3 - CRW (cont)TABLE 4 CRWTABLE 5 - SPW

Claims

Claims 1. A pesticidal composition comprising: A) a compound of Formula One (F1); F F FF1 and B) a biological agent selected from the group consisting of Bacillus species, Baclovirus species, Pseudomonas species, Beauveria species, Mycobacterium species, Mycorrhizal fungi, Trichoderma species, and Metarhizium species.

2. The pesticidal composition according claim 1, further comprising an active compound selected from the group consisting of insecticides, fungicides, and nematicides.

3. The pesticidal composition according to claim 2, wherein the active compound is selected from the group consisting of azoxystrobin, copper hydroxide, difenoconazole, ethaboxam, fludioxonil, fluopyram, fluoxastrobin, fluxapyroxad, inpyrfluxam, ipconazole, isoflucypram, mefenoxam, mefentrifluconazole, metalaxyl, myclobutanil, oxathiapiprolin, picoxystrobin, propiconazole, prothiaconazole, pydiflumetofen, pyroclostrobin, sedaxane, tebuconazole, thiabendazole, thiram, titriconazole and trifloxystrobin.

4. The pesticidal composition of claim 2, wherein the active compound is selected from the group consisting of abamectin, acetamiprid, benzpyrimoxan, bifenthrin, chlorantraniliprole, chlorfenapyr, cyantraniliprole, cyclobutrifluram, dimepropyridaz, fipronil, flonicamid, fluoxapiprolin, flupyradifurone, flupyrimin, fluxametamide, imidacloprid, indoxacarb, isocycloseram, lambda-cyhalothrin, methoxyfenozide, pymetrozine, pyriproxyfen, spidoxamat, Page 34 of 48spinetoram, spinosad, spiropidion, spirotetramat, sulfoxaflor, thiamethoxam, and triflumezopyrim.

5. The pesticidal composition according to claims 1-4, wherein the Bacillus species is selected from the group consisting of Bacillus thuringiensis, Bacillus amyloliquifaciens, Bacillus subtilis, Bacillus firmus, Bacillus pumilus, Bacillus sphaericus, 6. The pesticidal composition according to claims 1-5, wherein the Bacillus species is Bacillus thuringiensis var. kurstaki, Bacillus thuringiensis var. tenebrionis, or Bacillus thuringiensis var. aizawai.

7. The pesticidal composition according to claims 1-5, wherein the Bacillus species is Bacillus amyloliquifaciens var. PTA4838.

8. The pesticidal composition according to any of the claims 1-5, wherein Bacillus amyloliquifaciens sp. is Bacillus amyloliquifaciens MBI 600.

9. The pesticidal composition according to any of the claims 1-5, wherein ratio of A) F1, to B) biological agent, is 1:1 to 1:10000, preferably from 1:1 to 1:2000, preferably from 1:1 to 1:1000, and more preferably from 1:1 to 1:

500.

10. A method of controlling and / or combating a pest comprising applying the composition according to any of the claims 1-9 to a pest, to a locus of a pest, a plant susceptible to attack by a pest, sites where pest inhabits, or food supply of a pest.

11. A composition comprising a plant propagation material and the pesticidal composition according to any of the claims 1-9.

12. The composition according claim 11, wherein the plant propagation material is a seed.

13. A method of using the composition according to any of the claims 1-9 comprising providing the composition by coating a seed with the composition or by applying the composition in conjunction with the seeds, or prior to, or after the time of seeding.

14. A seed coated with the composition according to any of the claims 1-9. Page 35 of 48

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