Firming and line-smoothing composition and use thereof in eye creams

Abstract

A firming and line-smoothing composition and the use thereof in eye creams. The firming and line-smoothing composition comprises plant extracts and a polypeptide, wherein the plant extracts comprise Butyrospermum parkii butter, Crocus sativus extract, Zingiber zerumbet extract and Matricaria chamomilla flower oil. The firming and line-smoothing composition is suitable for skin care products such as eye creams, and is mild and non-irritating.

Description

A firming and wrinkle-reducing composition and its application in eye cream Technical Field

[0001] This application relates to the field of cosmetics, such as a firming and wrinkle-reducing composition and its application in an eye cream. Background Technology

[0002] Human skin is a vital barrier that prevents the loss of water, electrolytes, and other substances from the body, and blocks the invasion of harmful external substances. The integrity of the skin barrier is crucial for maintaining skin health. The skin barrier protects the body from external environmental damage, including preventing the invasion of harmful microorganisms, chemicals, pollutants, and physical damage (such as ultraviolet radiation). The skin barrier helps maintain skin hydration, preventing excessive water loss and thus keeping the skin soft and elastic. Compared to other areas of skin, the skin around the eyes is thinner and more sensitive, with delicate subcutaneous tissue, lower collagen content, and fewer skin appendages, including sweat glands and sebaceous glands. This makes the area prone to dehydration and lack of oil, leading to wrinkles and premature aging.

[0003] Irregular lifestyles, such as frequently staying up late and overeating, can easily lead to reduced blood circulation around the eyes, resulting in a series of eye problems such as puffiness, increased wrinkles, and crow's feet. A significant cause of wrinkles is insufficient moisture in the skin of these areas. Skin needs adequate hydration to function properly for metabolism. Therefore, effective moisturizing to balance the skin's moisture and oil levels, along with the use of natural, gentle ingredients to soothe the skin, can effectively improve firmness and reduce the appearance of wrinkles around the eyes. Thus, providing a gentle cosmetic product that effectively moisturizes while also firming and reducing wrinkles is of great importance. Summary of the Invention

[0004] The following is an overview of the subject matter described in detail herein. This overview is not intended to limit the scope of the claims.

[0005] This application provides a firming and wrinkle-reducing composition and its application in an eye cream.

[0006] In a first aspect, this application provides a firming and wrinkle-reducing composition, the firming and wrinkle-reducing composition comprising plant extracts and peptides;

[0007] The plant extracts include shea butter, saffron extract, ginger extract, and chamomile oil.

[0008] In this application, plant extracts and peptides were used in combination, and it was found that the plant extract components and peptides can work synergistically to have a better effect on firming and reducing wrinkles.

[0009] Furthermore, shea butter is rich in unsaturated fatty acids, which can enhance the skin's moisturizing ability and nourish dry skin, especially skin with damaged stratum corneum. It can also regulate product fluidity, improve viscosity, and enhance the product's sensory quality and user experience. Saffron extract, a natural component extracted from saffron flowers, mainly consists of pigments, volatile oils, and various organic compounds from the petals. It has whitening, antioxidant, and moisturizing effects, effectively improving skin pigmentation and dullness, enhancing skin resistance, and delaying the skin aging process. Red ginger extract inhibits the activity of elastase and tyrosinase and promotes collagen production, exhibiting excellent anti-wrinkle and anti-aging effects. Chamomile oil, an essential oil extracted from chamomile flowers, has calming, soothing, anti-inflammatory, and antioxidant effects.

[0010] In this application, the above four specific plant extracts were used in combination, and it was found that they have a significant synergistic effect in moisturizing and firming and reducing wrinkles.

[0011] In one embodiment, the mass ratio of the plant extract to the polypeptide is (0.1-4):(0.05-5), for example, it can be 4:0.05, 4:0.1, 4:0.5, 4:1, 1:1, 4:3, 4:5, 1:2, 1:3, 1:4, 1:5, 0.5:5, 0.1:5, etc. Other specific values ​​within this range can be selected, and will not be described in detail here.

[0012] In this application, when the ratio of plant extracts and peptides used is within the specific range mentioned above, a better firming and wrinkle-reducing effect is achieved.

[0013] In one embodiment, the polypeptide comprises any one or a combination of at least two of oligopeptide-215, palmitoyl pentapeptide-4, acetyl hexapeptide-8, conopeptide, carnosine, or acetyl tetrapeptide-5.

[0014] In one embodiment, the plant extract comprises, by weight, 0.5-12 parts of shea butter, 0.01-2 parts of saffron extract, 0.1-5 parts of ginger extract and 0.1-5 parts of chamomile oil;

[0015] The "0.5-12 portions" mentioned above can be, for example, 0.5 portions, 1 portion, 1.5 portions, 2 portions, 4 portions, 5 portions, 8 portions, 10 portions, 12 portions, etc.

[0016] The aforementioned "0.01-2 portions" can be, for example, 0.01 portions, 0.05 portions, 0.1 portions, 0.15 portions, 0.2 portions, 0.5 portions, 0.8 portions, 1 portion, 1.2 portions, 1.5 portions, 1.8 portions, 2 portions, etc.;

[0017] The above "0.1-5 parts" can be, for example, 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 part, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 5 parts, etc. Other specific point values ​​within this range can be selected, which will not be elaborated here.

[0018] In this application, when the proportions of each component in the plant extract are within the specific range mentioned above, it has a better firming and wrinkle-reducing effect.

[0019] The specific preparation process and source of the avocado fruit oil and chamomile oil components involved in this application are not limited. Products obtained by conventional extraction and preparation processes and regular commercially available products can be used in the scheme of this application.

[0020] The saffron extract involved in this application is not limited to a specific preparation process. When it is prepared using the following process, its synergistic effect with the other three components in firming and reducing wrinkles is more significant.

[0021] In one embodiment, the saffron extract is prepared by a method comprising the following steps:

[0022] Saffron, compound enzyme and water are mixed, ultrasonicated and filtered to obtain filtrate. The filtrate is concentrated and dried to obtain the saffron extract.

[0023] The complex enzyme comprises a combination of pectinase, β-glucanase, and flavor protease.

[0024] In this application, it was unexpectedly discovered that when using a complex enzyme solution containing pectinase, β-glucanase, and flavor protease to enzymatically extract the active substances from saffron, the combined use of the three enzymes can synergistically enhance the extraction effect, resulting in a saffron extract with higher activity and better efficacy. In addition, enzymatic hydrolysis under ultrasonic conditions can further improve the hydrolysis effect and obtain a saffron extract with even better efficacy.

[0025] In one embodiment, the mass ratio of the pectinase, β-glucanase, and flavor protease is (2-8):(1-5):(0.1-2);

[0026] Among them, the above "2-8" can be, for example, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5, 8, etc.;

[0027] The numbers "1-5" mentioned above can be, for example, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, etc.

[0028] The "0.1-2" mentioned above can be, for example, 0.1, 0.2, 0.4, 0.5, 0.6, 0.8, 1, 1.2, 1.4, 1.5, 1.6, 1.8, 2, etc. Other specific point values ​​within this range can be selected, which will not be elaborated here.

[0029] In this application, when the ratio of the three enzymes in the compound enzyme used is within the specific range mentioned above, the enzymatic extraction effect of saffron can be further improved.

[0030] In one embodiment, the amount of the compound enzyme added is 0.1‰-1‰ of the saffron mass, for example, it can be 0.1‰, 0.15‰, 0.2‰, 0.25‰, 0.3‰, 0.5‰, 0.6‰, 0.7‰, 0.8‰, 0.9‰, 1‰, etc. Other specific values ​​within this range can be selected, and will not be elaborated here.

[0031] In one embodiment, the ratio of saffron to water is 1g:(40-90)mL, for example, it can be 1g:40mL, 1g:45mL, 1g:50mL, 1g:55mL, 1g:60mL, 1g:65mL, 1g:70mL, 1g:72mL, 1g:75mL, 1g:80mL, 1g:85mL, 1g:90mL, etc. Other specific values ​​within this range can be selected, and will not be described in detail here.

[0032] In one embodiment, the power of the ultrasound is 200-400 W, such as 200 W, 250 W, 300 W, 350 W, 400 W, etc., and the enzymatic hydrolysis time is 5-30 min, such as 5 min, 7 min, 10 min, 12 min, 15 min, 20 min, 22 min, 25 min, 30 min, etc. Other specific values ​​within this range can be selected, and will not be described in detail here.

[0033] The preparation process of the red ginger extract involved in this application is not limited. When it is prepared using the following process, its synergistic effect with the other three components in firming and reducing wrinkles is more significant.

[0034] In one embodiment, the red ginger extract is prepared by a method comprising the following steps:

[0035] The red ginger was extracted by subcritical extraction, filtered to obtain a filtrate, and the filtrate was concentrated and dried to obtain the red ginger extract.

[0036] When subcritical extraction is used to extract red ginger raw materials, the extraction effect can be further improved. Compared with conventional hot water reflux extraction, the nutrients and bioactive substances in red ginger can be extracted more effectively, and the resulting extract has a better anti-wrinkle and wrinkle-reducing effect.

[0037] In one embodiment, the ratio of the red ginger to the subcritical extraction solvent is 1g:(15-40)mL, for example, it can be 1g:15mL, 1g:18mL, 1g:20mL, 1g:22mL, 1g:25mL, 1g:28mL, 1g:30mL, 1g:32mL, 1g:35mL, 1g:38mL, 1g:40mL, etc. Other specific values ​​within this range can be selected, and will not be described in detail here.

[0038] In one embodiment, the subcritical extraction temperature is 120-180℃, for example, 120℃, 125℃, 130℃, 135℃, 140℃, 145℃, 150℃, 160℃, 165℃, 170℃, 180℃, etc.; the time is 30-60 min, for example, 30 min, 35 min, 40 min, 45 min, 50 min, 55 min, 60 min. Other specific values ​​within this range can be selected, and will not be elaborated here.

[0039] Secondly, this application provides the use of the firming and wrinkle-reducing composition according to the first aspect in cosmetics;

[0040] The cosmetics include lotions, creams, toners, serums, or masks.

[0041] Thirdly, this application provides a firming and wrinkle-reducing eye cream, wherein the firming and wrinkle-reducing eye cream comprises 0.1-10 parts by weight of the firming and wrinkle-reducing composition described in the first aspect.

[0042] The "0.1-10 portions" mentioned above can be, for example, 0.1 portions, 0.2 portions, 0.5 portions, 0.8 portions, 1 portion, 2 portions, 3 portions, 4 portions, 5 portions, 6 portions, 8 portions, 10 portions, etc.

[0043] In one embodiment, the firming and wrinkle-reducing eye cream further comprises, by weight, any one or a combination of at least two of the following: 2-30 parts of moisturizer, 2-25 parts of emulsifier, 2-15 parts of skin moisturizer, 0.1-1 part of thickener, 0.5-3 parts of skin conditioning agent, 0.0005-0.01 parts of pH adjuster, 0.1-0.5 parts of antioxidant, 0.01-0.1 parts of chelating agent, or 40-70 parts of water.

[0044] The "2-30 portions" mentioned above can be, for example, 2 portions, 5 portions, 8 portions, 10 portions, 12 portions, 15 portions, 18 portions, 20 portions, 22 portions, 25 portions, 28 portions, 30 portions, etc.

[0045] The "2-25 portions" mentioned above can be, for example, 2 portions, 5 portions, 8 portions, 10 portions, 12 portions, 15 portions, 18 portions, 20 portions, 22 portions, 25 portions, etc.

[0046] The aforementioned "2-15 portions" can be, for example, 2 portions, 3 portions, 4 portions, 5 portions, 6 portions, 7 portions, 8 portions, 9 portions, 10 portions, 11 portions, 12 portions, 13 portions, 14 portions, 15 portions, etc.

[0047] The aforementioned "0.1-1 part" can be, for example, 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part, 1 part, etc.;

[0048] The aforementioned "0.5-3 portions" can be, for example, 0.5 portions, 0.6 portions, 0.7 portions, 0.8 portions, 0.9 portions, 1 portion, 1.2 portions, 1.5 portions, 1.8 portions, 2 portions, 2.2 portions, 2.5 portions, 2.8 portions, 3 portions, etc.

[0049] The aforementioned "0.0005-0.01 parts" can be, for example, 0.0005 parts, 0.001 parts, 0.0015 parts, 0.002 parts, 0.004 parts, 0.005 parts, 0.006 parts, 0.007 parts, 0.008 parts, 0.009 parts, 0.01 parts, etc.

[0050] The aforementioned "0.1-0.5 portions" can be, for example, 0.1 portions, 0.15 portions, 0.2 portions, 0.25 portions, 0.3 portions, 0.35 portions, 0.4 portions, 0.45 portions, 0.5 portions, etc.;

[0051] The aforementioned "0.01-0.1 parts" can be, for example, 0.01 parts, 0.02 parts, 0.03 parts, 0.04 parts, 0.05 parts, 0.06 parts, 0.07 parts, 0.08 parts, 0.09 parts, 0.1 parts, etc.;

[0052] The aforementioned "40-70 portions" can be, for example, 40 portions, 42 portions, 45 portions, 48 ​​portions, 50 portions, 52 portions, 55 portions, 58 portions, 60 portions, 62 portions, 65 portions, 68 portions, 70 portions, etc. Other specific values ​​within this range can be selected, which will not be elaborated here.

[0053] In one embodiment, the humectant comprises any one or a combination of at least two of the following: polydimethylsiloxane, squalane, glycerin, β-glucan, propylene glycol, 1,2-pentanediol, 1,2-hexanediol, octyl glycol, aminomethylpropanol, hydrogenated lecithin, or saccharide isomers.

[0054] In one embodiment, the emulsifier comprises any one or a combination of at least two of the following: polyglycerol-6 distearate, polyglycerol-3 beeswaxate, cetyl alcohol, cetearyl alcohol, behenyl alcohol, acrylate / C10-30 alkanol acrylate crosspolymer, sodium stearoyl glutamate, sodium acrylate / sodium acryloyl dimethyl taurate copolymer, sorbitan oleate, or PPG-13-decyltetradecyl alcohol polyether-24.

[0055] In one embodiment, the emollient comprises any one or a combination of at least two of jojoba esters, butylene glycol dioctanoate / didecanoate, pentaerythritol tetra(ethylhexanoate), myristyl myristate, isohexadecane, or polysorbate-80.

[0056] In one embodiment, the thickener comprises any one or a combination of at least two of xanthan gum, carbomer, or ethyl cellulose.

[0057] In one embodiment, the skin conditioning agent comprises any one or a combination of at least two of the following: β-alanylhydroxyprolyl diaminobutyrate benzylamine, nicotinic acid ester, lactic acid bacteria fermentation product, or yeast fermentation product.

[0058] In one embodiment, the pH adjuster includes citric acid and / or arginine.

[0059] In one embodiment, the antioxidant includes tocopheryl acetate and / or sodium metabisulfite.

[0060] In one embodiment, the chelating agent comprises disodium EDTA and / or sodium citrate.

[0061] Compared with related technologies, this application has the following advantages:

[0062] This application combines peptides and plant extracts to synergistically promote the firming and wrinkle-reducing effects of the composition. Furthermore, it utilizes four specific plant extracts: shea butter, saffron extract, red ginger extract, and chamomile oil. It was found that these four components can interact and positively influence each other, resulting in a synergistic effect on moisturizing and firming wrinkle reduction that is difficult for those skilled in the art to predict, thereby further enhancing the product's moisturizing and anti-wrinkle efficacy.

[0063] After reading and understanding the detailed description, other aspects can be understood. Detailed Implementation

[0064] To further illustrate the technical means and effects adopted in this application, the following describes the technical solution of this application in conjunction with optional embodiments of this application, but this application is not limited to the scope of the embodiments.

[0065] The following information pertains to the following products: avocado oil (Cetiol® SB 45) from Foshan Xin'an Chemical Trading Co., Ltd., with stearyl palmitate as the key active ingredient; chamomile oil (German chamomile oil) from Feike Company, with α-azapine alcohol as the key active ingredient; complex peptides (oligopeptide-215 + palmitoyl pentapeptide-4 + acetyl hexapeptide-8 + conopodeptide + carnosine) from Shenzhen Weiqi Technology Co., Ltd.; acetyl tetrapeptide-5 from Guangzhou Boyan Chemical Technology Co., Ltd.; pectinase from Shanghai Maclean Biochemical Technology Co., Ltd. (M6346); β-glucosidase from Shanghai Aladdin Biochemical Technology Co., Ltd. (G755171); and flavor protease from Shanghai Maclean Biochemical Technology Co., Ltd. (F861436). The mixed fermentation products (lactic acid bacteria fermentation products + yeast fermentation products) were sourced from Tibicosecret® products of Guangdong Marubi Biotechnology Co., Ltd.; the sugar isomers were sourced from PENTAVITIN products of Guangzhou Runpei Chemical Co., Ltd.

[0066] The weight percentages of the complex peptides, acetyl tetrapeptide-5, related commercially available plant extracts, sugar isomers, and mixed fermentation products mentioned below are based on the actual content of the active ingredients contained in the commercially available raw materials. The commercially available raw materials may also selectively contain any one or a combination of at least two of the following: solvents, humectants, thickeners, fillers, diluents, stabilizers, pH adjusters, antibacterial agents, antioxidants, or impurities within permissible limits.

[0067] Preparation Example 1

[0068] This preparation example provides a saffron extract, which is prepared by the following method:

[0069] (1) After freeze-drying and grinding saffron, mix it with compound enzyme and water. The amount of compound enzyme added is 0.5‰ of the mass of saffron. The material-liquid ratio of saffron to water is 1g:60mL. The compound enzyme consists of pectinase, β-glucanase and flavor protease in a mass ratio of 5:2:1. The mixture is subjected to ultrasonic enzymatic hydrolysis at a constant temperature of 50℃. The ultrasonic conditions are 300 W for 25 min.

[0070] (2) After the ultrasonic extract is filtered, the filtrate is collected, the residue is mixed with water, and the ultrasonic extraction process in step (1) and the filtration step in step (2) are repeated once. The filtrates are collected and combined, and then freeze-dried to obtain saffron extract.

[0071] This preparation example also provides a red ginger extract, prepared by the following method:

[0072] The pulverized red ginger was extracted at 150℃ with water as the extractant at a material-to-liquid ratio of 1g:30mL for 40 min using subcritical extraction. The filtrate was then filtered, concentrated under reduced pressure to remove solvent, and freeze-dried to obtain the red ginger extract.

[0073] Preparation Example 2

[0074] This preparation example provides a saffron extract, which is prepared by the following method:

[0075] (1) After freeze-drying and grinding saffron, mix it with compound enzyme and water. The amount of compound enzyme added is 0.25‰ of the mass of saffron. The material-liquid ratio of saffron to water is 1g:40mL. The compound enzyme consists of pectinase, β-glucanase and flavor protease in a mass ratio of 2:4.5:1.8. The mixture is subjected to ultrasonic enzymatic hydrolysis at a constant temperature of 55℃. The ultrasonic conditions are 350 W for 10 min.

[0076] (2) After the ultrasonic extract is filtered, the filtrate is collected, the residue is mixed with water, and the ultrasonic extraction process in step (1) and the filtration step in step (2) are repeated once. The filtrates are collected and combined, and then freeze-dried to obtain saffron extract.

[0077] This preparation example also provides a red ginger extract, prepared by the following method:

[0078] The pulverized red ginger was extracted at 160℃ with water as the extractant at a material-to-liquid ratio of 1g:35mL for 35 min. The extract was then filtered to obtain the filtrate, which was concentrated under reduced pressure to remove solvent, and then freeze-dried to obtain the red ginger extract.

[0079] Preparation Example 3

[0080] This preparation example provides a saffron extract, which is prepared by the following method:

[0081] (1) After freeze-drying and grinding saffron, it is mixed with compound enzyme and water. The amount of compound enzyme added is 0.8‰ of the mass of saffron. The material-liquid ratio of saffron to water is 1g:80mL. The compound enzyme consists of pectinase, β-glucanase and flavor protease in a mass ratio of 7:1:0.2. The mixture is subjected to ultrasonic enzymatic hydrolysis at a constant temperature of 55℃. The ultrasonic conditions are 240 W for 28 min.

[0082] (2) After the ultrasonic extract is filtered, the filtrate is collected, the residue is mixed with water, and the ultrasonic extraction process in step (1) and the filtration step in step (2) are repeated once. The filtrates are collected and combined, and then freeze-dried to obtain saffron extract.

[0083] This preparation example also provides a red ginger extract, prepared by the following method:

[0084] The pulverized red ginger was extracted at 130℃ with water as the extractant at a material-to-liquid ratio of 1g:15mL for 50 min. The extract was then filtered to obtain the filtrate, which was concentrated under reduced pressure to remove solvent, and then freeze-dried to obtain the red ginger extract.

[0085] Preparation Example 4

[0086] This preparation example provides a saffron extract, which uses saffron freeze-dried and ground from Preparation Example 1. The only difference between this preparation method and Preparation Example 1 is the enzyme composition in the complex enzyme. The difference is that it does not contain pectinase, and the reduced amount of pectinase is proportionally allocated to β-glucosidase and flavor protease. Other processing techniques and related parameters are the same as in Preparation Example 1.

[0087] Preparation Example 5

[0088] This preparation example provides a saffron extract, which uses saffron freeze-dried and ground from Preparation Example 1. The only difference between this preparation method and Preparation Example 1 is the enzyme composition in the complex enzyme. The difference is that it does not contain β-glucosidase, and the reduced amount of β-glucosidase is proportionally allocated to pectinase and flavor protease. Other processing techniques and related parameters are the same as in Preparation Example 1.

[0089] Preparation Example 6

[0090] This preparation example provides a saffron extract, which uses saffron freeze-dried and ground from Preparation Example 1. The only difference between this preparation method and Preparation Example 1 is the enzyme composition in the complex enzyme. The difference is that it does not contain flavor protease, and its reduced amount is allocated to pectinase and β-glucosidase in proportion. Other processing techniques and related parameters are the same as in Preparation Example 1.

[0091] Preparation Example 7

[0092] This preparation example provides a red ginger extract, which is prepared by the following method:

[0093] After crushing and sieving the red ginger, it was mixed with water at a ratio of 1g:15mL and extracted by reflux for 3.5 hours. The filtrate was then filtered through filter paper, concentrated, and freeze-dried to obtain the red ginger extract.

[0094] Example 1

[0095] This embodiment provides a firming and wrinkle-reducing composition, which, by weight, consists of 6 parts of shea butter, 1 part of saffron extract (Preparation Example 1), 2 parts of ginger extract (Preparation Example 1), 2 parts of chamomile oil, 2 parts of complex peptide (oligopeptide-215 + palmitoyl pentapeptide-4 + acetyl hexapeptide-8 + conopeptide + carnosine) and 6 parts of acetyl tetrapeptide-5.

[0096] Example 2

[0097] This embodiment provides a firming and wrinkle-reducing composition, which, by weight, consists of 2 parts of shea butter, 1.5 parts of saffron extract (Preparation Example 2), 5 parts of ginger extract (Preparation Example 2), 2.5 parts of chamomile oil, 0.5 parts of complex peptide (oligopeptide-215 + palmitoyl pentapeptide-4 + acetyl hexapeptide-8 + conopeptide + carnosine) and 4 parts of acetyl tetrapeptide-5.

[0098] Example 3

[0099] This embodiment provides a firming and wrinkle-reducing composition, which, by weight, consists of 10 parts of shea butter, 0.1 parts of saffron extract (Preparation Example 3), 1 part of ginger extract (Preparation Example 3), 0.9 parts of chamomile oil, 4 parts of complex peptides (oligopeptide-215 + palmitoyl pentapeptide-4 + acetyl hexapeptide-8 + conopeptide + carnosine) and 7 parts of acetyl tetrapeptide-5.

[0100] Example 4

[0101] This embodiment provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that the saffron extract used (Preparation Example 1) is replaced with an equal amount of saffron extract (Preparation Example 4).

[0102] Example 5

[0103] This embodiment provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that the saffron extract used (Preparation Example 1) is replaced with an equal amount of saffron extract (Preparation Example 5).

[0104] Example 6

[0105] This embodiment provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that the saffron extract used (Preparation Example 1) is replaced with an equal amount of saffron extract (Preparation Example 6).

[0106] Example 7

[0107] This embodiment provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that the red ginger extract (Preparation Example 1) is replaced with an equal amount of red ginger extract (Preparation Example 7).

[0108] Comparative Example 1

[0109] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain shea butter, and the reduced amount of shea butter is proportionally distributed among the three components: saffron extract, red ginger extract, and chamomile oil.

[0110] Comparative Example 2

[0111] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain saffron extract, and its reduced proportion is proportionally allocated to the three components: shea butter, red ginger extract, and chamomile oil.

[0112] Comparative Example 3

[0113] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain red ginger extract, and its reduced proportions are distributed proportionally to the three components: shea butter, saffron extract, and chamomile oil.

[0114] Comparative Example 4

[0115] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain chamomile oil, and its reduced proportions are distributed proportionally to the three components: shea butter, saffron extract, and red ginger extract.

[0116] Comparative Example 5

[0117] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain complex peptides and acetyl tetrapeptide-5, and the reduced amounts of these two components are proportionally distributed to four plant extract components: shea butter, saffron extract, red ginger extract, and chamomile oil.

[0118] Comparative Example 6

[0119] This comparative example provides a firming and wrinkle-reducing composition, which differs from Example 1 only in that it does not contain four plant extracts: shea butter, saffron extract, red ginger extract, and chamomile oil, and the reduced amounts of these four extracts are proportionally allocated to the two components, complex peptide and acetyl tetrapeptide-5.

[0120] Application Example 1

[0121] This application example provides a firming and wrinkle-reducing eye cream with the following formula:

[0122]

[0123] Its preparation method is as follows:

[0124] (1) Add the first moisturizer, the first emulsifier, the first skin moisturizer, the antioxidant and the firming and wrinkle-reducing composition (shea butter) to the oil phase pot, stir and heat to 75°C, and keep warm for 10 min.

[0125] (2) Add the second humectant, the second emulsifier, the thickener, the chelating agent (disodium ETDA) and some water to the aqueous phase pot, stir and heat to 80°C, and keep warm for 10 min.

[0126] (3) After the heat preservation is completed, the mixture in the water phase pot and the oil phase pot is pumped into the emulsification pot. After homogenization at 2500 rpm for 8 min, aminomethylpropanol, some water, sodium acrylate / sodium acryloyl dimethyl taurate copolymer, isohexadecane, polysorbate-80, and sorbitan oleate are added. After homogenization at 2000 rpm for 8 min, the temperature is lowered to 45℃, the remaining raw material components are added, and the mixture is stirred at 500 rpm for 10 min to prepare the eye cream product.

[0127] Application Example 2-7

[0128] This application example provides six firming and wrinkle-reducing eye creams. The only difference between the formulation and the application example is that the composition prepared in Example 1 is replaced with an equal amount of the composition prepared in Examples 2-7. Other ingredients and contents remain unchanged, and the preparation method is the same as in Application Example 1.

[0129] Comparative Application Examples 1-6

[0130] This comparative application example provides six firming and wrinkle-reducing eye creams. The only difference between the formulation and the application example is that the composition prepared in Example 1 is replaced with an equal amount of the composition prepared in Comparative Examples 1-6. Other ingredients and contents remain unchanged, and the preparation method is the same as in Application Example 1.

[0131] Test Example 1

[0132] Matrix efficacy testing and screening

[0133] (1) Healthy Chinese women with a facial lactic acid stinging test (LAST) score >3, dry, rough, dull, and loose facial skin, sensitive and red facial skin, and obvious nasolabial folds, under-eye wrinkles, crow's feet wrinkles, and tear trough wrinkles were selected. All subjects had no allergic diseases, no history of allergies to cosmetics or other topical preparations, and were habitually using basic moisturizing toners and lotions / creams daily. A total of 78 subjects were selected, aged 35-60 years, with a mean age of 46.3 ± 5.6 years. The subjects were divided into 13 groups of 6 people each. After arriving at the laboratory, the subjects cleansed their faces with facial cleanser, sat quietly for 30 minutes, and underwent a half-face test. After applying the product and massaging until absorbed, the skin was tested again after 30 minutes. Statistical analysis was performed on the changes in skin before and after the tests to obtain the rate of change.

[0134] (2) The test items include:

[0135] The Corneometer CM 825 (Courage & Khazaka, Germany) is used to test the moisture content of the stratum corneum of the skin.

[0136] The Cutometer MPA580 (Courage & Khazaka, Germany) is used to test skin elasticity and firmness.

[0137] (3) The firming and wrinkle-reducing compositions of Examples 1-7 and Comparative Examples 1-6 were dissolved in pure water to make the concentration of the composition in each group of samples 5%, and tested. The test environment was 20°C and 50% humidity, which met the requirements of the design scheme. Improvement / enhancement after using the product (%) = (data after use - data before use) / data before use × 100%; the results are shown in Table 1:

[0138]

[0139] The data in the table shows that:

[0140] (1) As can be seen from Examples 1 to 3, the firming and wrinkle-reducing composition provided in this application has significant moisturizing and firming effects, with Example 1 showing the best effect.

[0141] (2) By comparing Example 1 with Examples 4-6, it can be seen that the saffron extract in this application is extracted by enzymatic hydrolysis using a complex enzyme composed of three enzymes: pectinase, β-glucanase and flavor protease. The three enzymes can work together to promote the hydrolysis effect, further improve the extraction effect of the relevant active ingredients in saffron, and obtain a saffron extract with better effect.

[0142] (3) By comparing Example 1 and Example 7, it can be seen that the red ginger extract prepared by subcritical extraction in this application has better effect than the red ginger extract prepared by traditional heating and reflux.

[0143] (4) By comparing Example 1 with Comparative Examples 1-4, it can be seen that when Comparative Examples 1-4 do not contain any of the four components of shea butter, saffron extract, red ginger extract and chamomile oil, the effects of the prepared composition on moisturizing and skin firming are worse than those of Example 1. It can be seen that the combination of four components of shea butter, saffron extract, red ginger extract and chamomile oil in this application can work together to enhance the skin condition.

[0144] (5) By comparing Example 1 with Comparative Examples 5-6, it can be seen that the combination of polypeptide and plant extract components in this application can synergistically enhance the moisturizing and firming effects of the product.

[0145] Test Example 2

[0146] Eye cream efficacy test

[0147] (1) Healthy Chinese women with a facial lactic acid stinging test (LAST) score >3, dry, rough, dull, and loose facial skin, sensitive and red facial skin, and obvious nasolabial folds, under-eye wrinkles, crow's feet wrinkles, and tear trough wrinkles were selected. All subjects had no allergic diseases, no history of allergies to cosmetics or other topical preparations, and were accustomed to using basic moisturizing toners and lotions / creams daily. A total of 78 subjects were selected, with an age range of 35-60 years and a mean age of 46.3±5.6 years. The subjects were divided into 13 groups of 6 people each.

[0148] (2) After cleansing and applying toner each night, the subjects applied an appropriate amount of eye cream evenly around the eyes, gently dotting it onto the skin around the eyes and nasolabial folds. Using the crystal massage head, they gently massaged the eye area from the inside out and from the bottom up until absorbed. This was done once daily for 28 consecutive days. The changes in the skin before and after treatment were statistically analyzed to obtain the rate of change.

[0149] (3) The test items include:

[0150] The Corneometer CM 825 is used to test the moisture content of the stratum corneum of the skin.

[0151] The Cutometer MPA580 skin elasticity tester measures skin elasticity (R2) and firmness (F4).

[0152] The Mexameter MX18 skin melanin and hemoglobin analyzer measures the content of hemoglobin and melanin in the skin.

[0153] The Glossymeter GL 200 is used to test skin gloss.

[0154] The Evaskin-S5 rapid optical imaging system for skin testing the roughness of under-eye wrinkles.

[0155] (3) The test products were the eye cream products prepared in Application Examples 1-7 and Comparative Application Examples 1-6. The test environment was 20℃ and 50% humidity, which met the requirements of the design. The improvement / enhancement after using the product (%) = (data after use - data before use) / data before use × 100%. The results are shown in Table 2.

[0156]

[0157] The data in the table shows that the combination of peptides and plant extracts in this application can synergistically enhance the product's soothing, moisturizing, firming, and wrinkle-reducing effects. Furthermore, the use of four plant extracts—shea butter, saffron extract, ginger extract, and chamomile oil—also demonstrates a synergistic effect in soothing, moisturizing, firming, and wrinkle-reducing properties.

[0158] Test Example 3

[0159] Eye cream product wrinkle reduction effect test

[0160] (1) The inclusion criteria and product usage methods for the subjects were the same as those in test case 2. The Evaskin-S5 skin rapid optical imaging system was used to test and record the improvement effects of each line on the nasolabial folds, tear troughs, under-eye wrinkles and crow's feet.

[0161] (2) The test product was the eye cream product prepared in Application Example 1. The test environment was 20℃ and 50% humidity, which met the requirements of the design scheme. Improvement / enhancement after using the product (%) = (data after use - data before use) / data before use × 100%. The results are shown in Table 3.

[0162]

[0163] The data in the table shows that the eye cream product prepared in this application has excellent anti-wrinkle effect. The combination of peptides and four specific plant extracts makes the product have a good effect on reducing various wrinkles and has excellent firming effect.

[0164] Test Example 4

[0165] Product safety testing

[0166] Thirty-five women and thirty-five men were selected according to the inclusion criteria to participate in the trial, and randomly divided into seven groups (five men and five women in each group) to receive the trial. An appropriate amount of sample was placed in the drug compartment of the test strip. The test strip containing the sample was then applied to the flexor surface of the subject's forearm using medical tape, and left for 24 hours. Thirty minutes after removing the test strip, and after the indentation disappeared, the skin reaction was observed. For those with negative results, re-observation was conducted at 24 hours and 48 hours after the trial, and the skin reaction results were recorded. The grading criteria for the degree of reaction are shown in the table below.

[0167]

[0168] The results showed that the products prepared in Examples 1-7 all exhibited negative reactions at 24 h and 48 h after the test, with no irritation or erythema. Therefore, the eye cream product prepared in this application is non-irritating to the skin and showed no positive reaction, proving that the product is highly safe, has low irritation, and is relatively mild.

[0169] The applicant declares that this application illustrates the technical solution of this application through the above embodiments, but this application is not limited to the above embodiments, that is, it does not mean that this application must rely on the above embodiments to be implemented. Those skilled in the art should understand that any improvements to this application, equivalent substitutions of the raw materials of this application's products, addition of auxiliary components, selection of specific methods, etc., all fall within the protection scope and disclosure scope of this application.

[0170] The optional embodiments of this application have been described in detail above. However, this application is not limited to the specific details of the above embodiments. Within the scope of the technical concept of this application, various simple modifications can be made to the technical solution of this application, and these simple modifications all fall within the protection scope of this application.

[0171] It should also be noted that the various specific technical features described in the above embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, this application will not describe the various possible combinations separately.

Claims

A firming and wrinkle-reducing composition comprising plant extracts and peptides; The plant extracts include shea butter, saffron extract, ginger extract, and chamomile oil. According to claim 1, the firming and wrinkle-reducing composition, wherein, The mass ratio of the plant extract to the polypeptide is (0.1-4):(0.05-5). The firming and wrinkle-reducing composition according to claim 1 or 2, wherein, The polypeptide includes any one or a combination of at least two of the following: oligopeptide-215, palmitoyl pentapeptide-4, acetyl hexapeptide-8, conopeptide, carnosine, or acetyl tetrapeptide-5. According to claim 1, the firming and wrinkle-reducing composition, wherein, The plant extracts, by weight, include 0.5-12 parts of shea butter, 0.01-2 parts of saffron extract, 0.1-5 parts of ginger extract, and 0.1-5 parts of chamomile oil. The firming and wrinkle-reducing composition according to any one of claims 1-4, wherein, The saffron extract is prepared by a method comprising the following steps: Saffron, compound enzyme and water are mixed, ultrasonicated and filtered to obtain filtrate. The filtrate is concentrated and dried to obtain the saffron extract. The complex enzyme comprises a combination of pectinase, β-glucanase, and flavor protease. According to claim 5, the firming and wrinkle-reducing composition, wherein, The mass ratio of pectinase, β-glucanase and flavor protease is (2-8):(1-5):(0.1-2). The firming and wrinkle-reducing composition according to claim 5 or 6, wherein, The amount of the compound enzyme added is 0.1‰-1‰ of the saffron mass. The firming and wrinkle-reducing composition according to any one of claims 5-7, wherein, The ratio of saffron to water is 1g:(40-90)mL. The firming and wrinkle-reducing composition according to claim 1 or 4, wherein, The red ginger extract is prepared by a method comprising the following steps: The red ginger was extracted using subcritical extraction, filtered to obtain a filtrate, and then concentrated and dried to obtain the red ginger extract. The application of a firming and wrinkle-reducing composition according to any one of claims 1-9 in cosmetics; The cosmetics include lotions, creams, toners, serums, or masks. A firming and wrinkle-reducing eye cream, in which... The firming and wrinkle-reducing eye cream comprises 0.1-10 parts by weight of the firming and wrinkle-reducing composition according to any one of claims 1-9. According to claim 11, the firming and wrinkle-reducing eye cream, wherein, The firming and wrinkle-reducing eye cream further comprises, by weight, any one or a combination of at least two of the following: 2-30 parts moisturizer, 2-25 parts emulsifier, 2-15 parts skin moisturizer, 0.1-1 part thickener, 0.5-3 parts skin conditioning agent, 0.0005-0.01 parts pH adjuster, 0.1-0.5 parts antioxidant, 0.01-0.1 parts chelating agent, or 40-70 parts water. According to claim 12, the firming and wrinkle-reducing eye cream, wherein, The humectant includes any one or a combination of at least two of the following: polydimethylsiloxane, squalane, glycerin, β-glucan, propylene glycol, 1,2-pentanediol, 1,2-hexanediol, caprylyl glycol, aminomethylpropanol, hydrogenated lecithin, or saccharide isomers. The firming and wrinkle-reducing eye cream according to claim 12 or 13, wherein, The emulsifier comprises any one or a combination of at least two of the following: polyglycerol-6 distearate, polyglycerol-3 beeswaxate, cetyl alcohol, cetearyl alcohol, behenyl alcohol, acrylate / C10-30 alkanol acrylate crosspolymer, sodium stearoyl glutamate, sodium acrylate / sodium acryloyl dimethyl taurate copolymer, sorbitan oleate, or PPG-13-decyltetradecyl alcohol polyether-24. The firming and wrinkle-reducing eye cream according to any one of claims 12-14, wherein, The emollients include any one or a combination of at least two of the following: jojoba esters, butylene glycol dioctanoate / didecanoate, pentaerythritol tetra(ethylhexanoate), myristyl myristate, isohexadecane, or polysorbate-80. Optionally, the thickener includes any one or a combination of at least two of xanthan gum, carbomer, or ethyl cellulose; Optionally, the skin conditioning agent includes any one or a combination of at least two of the following: β-alanylhydroxyprolyl diaminobutyrate benzylamine, nicotinic acid ester, lactic acid bacteria fermentation product, or yeast fermentation product; Optionally, the pH adjuster includes citric acid and / or arginine; Optionally, the antioxidant includes tocopheryl acetate and / or sodium metabisulfite; Optionally, the chelating agent includes disodium EDTA and / or sodium citrate.

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