Load vessel draining system and method

Abstract

A load vessel draining system for use with a drug purification system. The system includes a load vessel, a liquid handling module coupled to the load vessel and configured to draw fluid from the load vessel, and a chase solution vessel coupled to the load vessel. A backflow mechanism is coupled to each of the chase solution vessel and the load vessel, and the backflow mechanism is configured to at least selectively prevent fluid from the load vessel from prematurely backflowing into the chase solution vessel. So configured, the chase solution from the chase solution vessel is added to the load vessel upon one or more of: (1) the load vessel reaching an empty state; or (2) pressure within the load vessel exceeding a predetermined threshold.

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