Passaging of cells
The use of cellulose nanofibers as a support matrix for adherent cells in industrial-scale culturing eliminates the need for detachment during passaging, enhancing scalability and reducing contamination, thus improving cell production efficiency.
WO2026132129A1 Publication Date: 2026-06-25CELLEVATE AB
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Patent Information
- Application Number
- PCT/EP2025/087842
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-12-20
- Filing Date
- 2025-12-17
- Publication Date
- 2026-06-25
AI Technical Summary
Technical Problem
The process of passaging adherent cells in industrial-scale cell culturing is labor-intensive, time-consuming, and prone to contamination due to the need for enzymatic or mechanical detachment from the support matrix, which complicates scalability and productivity.
Method used
A method utilizing cellulose nanofibers as a support matrix that allows direct transfer of attached cells to a new culture vessel without detachment, ensuring cell viability and reducing contamination risks.
Benefits of technology
This method significantly reduces production time and contamination risks while maintaining healthy cell proliferation, enabling high-throughput and scalable cell production.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention relates to a methodology for simple passaging of cells during cell culturing. The method is easily applicable to industrial scale cell culturing and requires no detachment of adherent cells from the support matrix upon passaging.
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