Ventilation system

Abstract

The present invention discloses a ventilation system (1) for ventilating a patient (7) with respiratory gas, comprising a ventilator (2), a nebulising device (4), a control device (3) and an output device (5), wherein the control device (3) is communicatively connected to the ventilator (2), the nebulising device (4) and the output device (5), wherein the output device (5) is designed to present data from the ventilator (2), the nebulising device (4) and / or the control device (3) and / or to process inputs of an operator, wherein the control device (3) is designed to control the nebulising device (4) on the basis of at least one ventilation parameter for medicament delivery, and wherein the control device (3) is furthermore designed to calculate a depletion time, which indicates an expected time at which a medicament container of the nebulising device (4) runs out of medicament, on the basis of at least one depletion parameter and to output same on the output device (5).

Description

[0001] Ventilation system

[0002] The present invention relates to the field of medical technology and therein to a ventilation system for ventilating a patient, comprising a ventilator, a nebulizer, a control unit, and a display unit. In particular, the present invention relates to the interaction between the control unit and the nebulizer.

[0003] In a hospital setting, patients are often treated with other medical devices in addition to a ventilator. They may be connected to various systems simultaneously, including vital sign monitors, infusion systems, and the like. Coordinating these medical devices at the same time is complex and time-consuming. The nebulizer used in ventilation ensures the targeted delivery of aerosolized medications into the patient's airways and must therefore be integrated into the overall treatment plan in such a way that the generated aerosol is effectively inhaled and achieves the desired effect in the lungs. It is therefore essential for the operating personnel to continuously monitor the nebulizer and, in particular, its effect on the patient during ventilation to ensure precise dosing, optimal medication deposition, and safe integration into the ventilation cycle.

[0004] With conventional ventilation systems, there is hardly any way to view or adjust the parameters crucial for nebulization on the ventilator itself. Sometimes the nebulizer, which may be a mesh or vibrating membrane nebulizer, can be connected to a power supply provided by the ventilator. Some systems offer the option of switching the nebulizer on or off via the ventilator's controls. The operator is therefore aware that the nebulizer is switched on or off during active ventilation. However, further information beyond switching the nebulizer on or off is not readily available.

[0005] Nebulization devices used up to now are designed so that different medication liquids are contained in corresponding containers of the nebulization device or...

[0006] 15012 P 4981 WO are provided in the patient's own tanks. These must be replaced after each ventilation procedure. During prolonged ventilation, it may be necessary to use more than one container of medication fluid to achieve the desired effect on the patient. Consequently, it is desirable for the operating personnel to be informed, for example, when such a medication container needs to be replaced.

[0007] It is therefore the object of the present invention to provide a ventilation system that overcomes the disadvantages described above in previously used ventilation systems, enables the integration of nebulization parameters into the ventilation process, is simply structured and easy to assemble as an integrated system, and enables reliable and effective ventilation of a patient with optimized drug delivery through the nebulization device through a dynamic interaction of its components.

[0008] This problem is solved by the subject matter with the features of independent claim 1. Exemplary and advantageous embodiments are the subject of the dependent claims.

[0009] According to the invention, a ventilation system for ventilating a patient with respiratory gas is provided, comprising a ventilator, a nebulizer, a control unit, and a display unit, wherein the control unit is communicatively connected to the ventilator, the nebulizer, and the display unit. The display unit is configured to display data from the ventilator, the nebulizer, and / or the control unit and / or to process inputs from an operator. The control unit is configured to control the nebulizer for medication delivery based on at least one ventilation parameter.The control unit is further configured to calculate an idle time point, which indicates the expected idle time of a drug container in the nebulization device, based on at least one idle time parameter and to output it on the display unit.

[0010] The nebulization device can be of different types, for example a nozzle or jet nebulizer that uses compressed air or oxygen as a propellant, an ultrasonic nebulizer that generates fine particles without additional gas flow, or a vibrating nebulizer.

[0011] 15012 P 4981 WOmembrane or mesh nebulizer, which generates fine particle size with high efficiency and is suitable and optimized for use in mechanical ventilation.

[0012] The display unit can be integrated into one or more components of the ventilation system, preferably the ventilator, as this is typically the central device used to configure ventilation settings and display data during ventilation monitoring. However, the communicative integration of all components of the ventilation system also allows, for example, data from the nebulizer or an optional humidifier to be displayed on the unit. Input of control parameters for the nebulizer and other components via the display unit is also possible. The display unit can include several different displays and / or display types, such as a screen, LEDs, traffic light-style indicators, combinations thereof, and the like.One or more control elements, such as a display that is at least partially touch-sensitive, buttons, rotary controls, sliders, or combinations thereof, can be integrated into the display device. The display device may include elements for reproducing acoustic or haptic signals, such as speakers, buzzers, vibration elements, and the like. The display device may also be a touchscreen, thus simultaneously incorporating both display and control elements.

[0013] The control unit can be integrated into the ventilator and may include one or more processing units and / or memory. Alternatively or additionally, it can be integrated into other components, such as the display unit, or it can be designed as a separate component of the ventilation system. Communication between the components of the ventilation system can be wired and / or wireless.

[0014] By controlling the nebulizer via the control unit, medication delivery can be optimally integrated into the ventilation process, thus optimizing its effect for the patient. Data from the entire ventilation process converges in the control unit. This provides the operating personnel with immediate and comprehensive information that links the functions of the ventilator with those of the nebulizer.

[0015] 15012 P 4981 Combine the ventilation system and provide an optimized assessment basis for the ventilation curtain.

[0016] At least one ventilation parameter can be selected from a group that includes the following parameters: ventilation mode, ventilation rate, ventilation pressure, airflow, tidal volume, respiratory rate, inspiratory time (I), expiratory time (E), ratio of inspiratory time to expiratory time (I:E), flow pattern and other adjustable parameters such as clinical parameters of the patient.

[0017] The ventilation mode can include volume-controlled ventilation, pressure-controlled ventilation, adaptive support ventilation, pressure-supported spontaneous breathing, bilevel ventilation, and lung recruitment maneuvers.

[0018] Ventilation pressure determines the force with which the breathing gas is delivered into the lungs. Key pressure parameters include peak inspiratory pressure (PIP), the highest pressure reached in the airways during inspiration. PIP depends on lung compliance and airway resistance, is individually adjusted for each patient, and is typically around 15-30 cmH2O. Plateau pressure (Pplat) is the pressure at the end of inspiration, when airflow ceases, and serves as a marker for lung compliance. Positive end-expiratory pressure (PEEP) is the pressure remaining in the airways at the end of expiratory flow. PEEP prevents alveolar collapse and improves gas exchange. Typical PEEP values ​​are 5-10 cmH2O.

[0019] The tidal volume (VT) is the volume of air delivered to the lungs with each breath.

[0020] Airflow is the rate at which respiratory gases are supplied and indicates how quickly the respiratory gas flows into the lungs during inspiration. Typical airflow values ​​are approximately...

[0021] 30 - 60 l / min. Regarding the flow pattern, the airflow does not have to be constant (square wave), but can also be decelerating, i.e., high at the beginning of inspiration and then decreasing.

[0022] 15012 P 4981 WO The inspiratory time (I) is the duration of inhalation, i.e., the time spent inhaling. Normal values ​​for inspiratory time are approximately 0.8–1.2 seconds. The expiratory time (E) is the duration of exhalation, i.e., the time spent exhaling. It should be long enough to avoid air stasis. The I:E ratio (inspiratory-expiratory ratio) indicates how long inhalation takes compared to exhalation. Typical values ​​are, for example, 1:2, i.e., inhalation is half as long as exhalation, or 1:3 to 1:4 in obstructive patients.

[0023] Other ventilation parameters can be clinical parameters of the patient such as blood pressure, cardiac output, central venous pressure, metabolic parameters, pH value, heart rate, blood parameters, body temperature, body weight, age, oxygen saturation, neurological diseases, neuromuscular diseases or nutritional status.

[0024] The at least one idle parameter can be selected from a group that includes: nebulizer type, nebulization rate, size of the drug reservoir in the nebulizer, drug level in the nebulizer, rate of change of the drug level, nebulization duration, power consumption of the nebulizer, ventilation rate, ventilation mode, inspiratory time (I), expiratory time (E), ratio of inspiratory time to expiratory time (I:E).

[0025] The nebulizer type is the type of nebulization device as described above, e.g. jet nebulizer or compressed air nebulizer, ultrasonic nebulizer or mesh nebulizer with vibrating membrane.

[0026] The nebulizer rate is the flow rate at which the medication is delivered into the inspiratory tube. A typical nebulizer rate is 0.2–1.0 ml / min.

[0027] The size of the medication reservoir in the nebulization device refers to the volume of the medication reservoir, i.e., the container with the medication liquid to be nebulized, and optionally its condition when the medication reservoir is installed in the nebulization device.

[0028] The medication level in the nebulizer is another idle parameter that can be measured using level sensors. The more accurate the level measurement,

[0029] The more precise the prediction of the idle time point, the better the accuracy. From several closely spaced level measurements, the rate of change of the drug level can be derived, and from this, together with other idle parameters, the idle time point or earlier times such as predetermined remaining durations in minutes or seconds can be determined, which can be displayed or announced audibly to the operating personnel.

[0030] The nebulization duration is another idle parameter and can be roughly preset for certain ventilation parameters and then continuously updated by determining and calculating further idle parameters. It is typically 5-10 minutes, but should be individually adjusted to ensure effective medication absorption.

[0031] The power consumption of the nebulizer represents another idle-time parameter, because depending on the nebulizer type, medication delivery can depend on how much power the nebulizer requires to function correctly. Standard values ​​or curves and stored profiles for specific medications can be incorporated into the calculation. The deviation of the actual values ​​from the reference curves allows conclusions to be drawn about the expected idle time of the medication container.

[0032] The respiratory rate represents the number of breaths per minute a patient receives during mechanical ventilation. It is a key parameter for controlling ventilation and influences CO2 elimination and oxygenation. The respiratory rate has a significant impact as an idle parameter. The higher the rate, the greater the amount of medication delivered per unit of time. With synchronized nebulization, i.e., when nebulization occurs only during inspiration, medication deposition in the patient is optimized. The control unit synchronizes nebulization with the respiratory cycle, including potential optimizations such as specific time offsets between the nebulizer activation and the start of inspiration, or between the nebulizer deactivation and the end of inspiration.

[0033] The ventilation mode described above can be an idle parameter, because the type of ventilation can have an influence on drug delivery.

[0034] 15012 P 4981 WO In embodiments, the idle time point is calculated based on the drug level and / or the rate of change of the drug level during an inspiration period. Several, preferably consecutive, inspiration periods can also be considered.

[0035] In a preferred embodiment, a display shows pressure, flow rate, and volume, as well as a countdown to the anticipated end of nebulization due to an empty reservoir. In this embodiment, the control unit directs the nebulizer according to predetermined settings, instructing it to nebulize only during inspiration, with an I:E ratio of 1:1. Thus, the control unit regulates the nebulizer such that it nebulizes only during inspiration, using a 1:E ratio as the ventilation parameter.

[0036] In another embodiment, the nebulizer type is detected as an idle parameter. For each nebulizer type, a specific nebulization rate is defined, such as a medication nebulization rate of 1 ml per 150 s and a reservoir size of 6 ml. The control unit then calculates the idle time point based on this data. With the specified standard volume of 6 ml, the nebulizer can nebulize continuously during both inspiration and expiration for a total duration of 900 s, or 15 minutes. With nebulization only during inspiration and a 1:1 l:E ratio, the initial 6 ml medication volume lasts twice as long, i.e., 30 minutes. The expected idle time point can be specified either as the remaining nebulization time or countdown, or as the current time plus 30 minutes.

[0037] In another embodiment, the nebulizer type and power consumption of the nebulization device are known. It is documented that the nebulization device nebulizes a quantity of 1 ml in a duration of 150 s with a power consumption of 8 W and a quantity of 1 ml in a duration of 300 s with a power consumption of 7.5 W. With a volume or reservoir size of 6 ml, an I:E ratio of 1:1 (i.e., nebulization only during inspiration), and a power consumption of 7.5 W, the total nebulization duration is 60 minutes.

[0038] 15012 P 4981 WO In a further embodiment, the nebulizer type is known and it is documented that the nebulizing device nebulizes 1 ml per 150 s with a power consumption of 8 W. With a ventilation parameter I:E ratio of 1 :3, the nebulization lasts a total of 60 minutes.

[0039] In another embodiment, the ventilation parameter is set to 1:1 as an I:E ratio. An optical sensor is located in the reservoir, which allows the control unit to calculate, after nebulization has begun, that there is a consumption of 1 ml per 150 seconds. This results in a nebulization duration of 30 minutes with a medication reservoir size of 6 ml.

[0040] The at least one idle parameter can include actually measured and / or stored values ​​or data. The stored data can include empirical values ​​for patients with similar physiological characteristics, standard curves for specific medications, previous ventilation procedures for the same patient, or information about nebulizers of the same or different types used in the past. The control unit is configured to relate the actually measured values ​​to the stored data and / or compare them to relative or absolute threshold values.

[0041] In some embodiments, the ventilation system may include a humidification unit for humidifying the breathing gas, which is communicatively connected to the control unit. A humidification unit, or breathing air humidifier, in a ventilation system serves to warm and humidify the inhaled air to protect the airways and prevent secretion retention and airway irritation. The control unit may be configured to consider actual and / or stored data associated with the humidification unit when calculating the idle time of the nebulizer. The information relevant to humidification, acquired by one or more sensors in the ventilation system, may be displayed on the display unit alongside the ventilation parameters and / or idle parameters.

[0042] In certain embodiments, the nebulizing device may have at least one sensor configured to measure the fill level of medication liquid.

[0043] 15012 P 4981 WOsen. Possible sensors include a capacitive sensor, a resistance sensor, a weight sensor, an ultrasonic sensor, and an optical sensor. Capacitive level sensors measure the change in capacitance between two electrodes as the liquid in the nebulizer changes. Liquids have a different dielectric constant than air, which allows the sensor to detect the fill level. Optical level sensors work by using light refraction or reflection, with an infrared or laser beam striking the liquid surface. Changes in the reflection pattern indicate the fill level. They operate without contact and therefore do not affect medication quality. Optical level sensors are well-suited for mesh nebulizers. Ultrasonic level sensors send an ultrasonic signal into the liquid. The time it takes for the signal to reflect indicates the fill level. Resistance sensors, or...Conductivity-based level sensors utilize the electrical conductivity of the liquid. Two electrodes are positioned at different heights. When the liquid no longer touches the upper sensor, a low level is detected. These sensors are primarily used in jet nebulizers. Other possible sensors in nebulization systems include flow sensors, pressure sensors, temperature and humidity sensors, optical sensors, spectroscopic sensors, and capnography sensors (CO2 sensors). They ensure that the correct medication is delivered, detect leaks or blockages, reduce medication loss, and optimize medication deposition.

[0044] In further embodiments, the display device can include a display of at least one of the following indicators: medication level in the nebulizer, elapsed nebulization time, remaining nebulization time, and idle time point. These indicators represent the corresponding idle parameters, with certain values ​​being extremely important for the operating personnel. With certain combinations of values, the operating personnel may need to act very quickly to ensure the smoothest possible continuation of the ventilation process.

[0045] In certain embodiments, the control unit and / or the display unit is configured to output an electrical, optical, acoustic, or haptic alarm signal. The alarm signal can indicate an actual value or a change value of an idle parameter or a combination of specific idle parameters. Alarm systems in mechanical ventilation are essential for the early detection of critical changes in lung mechanical properties and for timely intervention.

[0046] 15012 P 4981 WO to take action. Electrical alarm signals include digital signals that can be sent to external monitoring systems, networks, or control units. This enables automatic integration into clinical monitoring systems through direct forwarding to central monitors or remote monitoring, e.g., in intensive care units. Together with the recording and analysis of previous data, trend monitoring of specific ventilation parameters becomes possible. This analytical data can be combined, for example, with artificial intelligence (AI) and decision support systems, resulting in automatic adjustment of ventilation. Finally, electrical signals do not represent a noise burden for operating personnel and can still be displayed on screens. Optical alarm signals, such as...LED displays, color graphics in displays, or color-coded alarms improve rapid recognition for staff, especially in noisy environments. Color coding allows for prioritization, e.g., traffic light colors (green = normal, yellow = warning, red = emergency). Visual alarm signals can be combined with other alarm systems, which reinforces the perception of the warning signals. The effects of audible alarm signals, i.e., tones or voice announcements, are immediately perceptible, even without visual contact. This can be particularly important for intensive care units with multiple patients. Furthermore, prioritization is possible due to different tones for varying levels of severity. Signal tones also increase reaction speed and can thus lead to the immediate attention of medical staff. Mechanical vibrations or haptic / tactile feedback, e.g.,Wristbands or smart devices are particularly well-suited for individual alerts to caregivers or doctors, as the signals can be discreetly sent to mobile devices (smartwatches, pagers). This is ideal in environments where audible alarms would be disruptive. It provides immediate, personal notification, which is especially helpful for mobile care teams.

[0047] In one embodiment, the data from the ventilator and the nebulizer can be displayed side-by-side on the display unit. This is advantageous for the operating personnel compared to previous systems where the nebulizer data was not visible at all, or only parts of it, on a display unit located separately from the ventilator.

[0048] 15012 P 4981 WOIn embodiments, the display unit includes controls that can be activated by an operator to operate the nebulizer. In some cases, considering certain data on the display unit, it may be useful to directly influence the nebulizer curtain, for example, when medication delivery has ceased due to a lack of active ingredient and a canister needs to be replaced. Based on the displayed data, the operator can then decide whether only the nebulization needs to be interrupted or whether other adjustments are necessary.

[0049] It is pointed out that in this disclosure, when an element is described as "connected to" or "coupled with" or "electrically coupled with" another element, the element may be directly connected or coupled, or there may be intermediate elements.

[0050] The terms "memory" or "memory device," as used herein, refer to a non-volatile, computer-readable storage medium capable of storing program instructions, machine code, or programming code for execution by one or more processors. References to "memory" or "memory device" are to be understood as referring to one or more memories or storage devices. Memory may, for example, be multiple memories within the same system. However, memory may also be multiple memories distributed across multiple systems or computer devices.

[0051] A "controller" or "control device," as the term is used herein, is a computer-based device comprising hardware, software, and / or firmware for performing one or more of the process steps disclosed herein. References herein to a control device are to be construed as referring to one or more control devices. A control device may, for example, comprise one or more microcontrollers, or one or more microprocessors or processor cores. A control device may also refer to a collection of control devices or processors in a single system or be distributed across a plurality of computer systems. The term "computer" is to be interpreted, where possible, as referring to a collection or network of computers or computer devices, each comprising a processor or processors. Instructions of a computer program may be issued by a plurality of

[0052] 15012 P 4981 WO control units or processors that are present in the same computer or that are distributed across multiple computers. In particular, by specifying the idle time parameters, the expected idle time of the nebulizer can be predicted as accurately as possible. This enables the operating personnel to react to the expected idle time and take appropriate steps, such as adjusting and / or interrupting nebulization and / or ventilation, changing a ventilation mode and / or a ventilation parameter, and / or seeking medical advice early.

[0053] Further advantages and features of the present invention will be described below with reference to the accompanying drawings.

[0054] Fig. 1 is a schematic representation of an embodiment of the ventilation system according to the invention.

[0055] Fig. 2 is a schematic representation of a display device of a ventilation system according to Fig. 1.

[0056] Figure 1 shows a ventilation system 1 comprising a ventilator 2, a control unit 3, a nebulizer 4, a display unit 5, and a ventilation circuit 15, or breathing tube system with flexible tubes, which connects the ventilation system 1 to a patient 7. The ventilation circuit 15 comprises an inspiratory tube 6 and an expiratory tube 8, which are connected to each other at a Y-connector 9. The Y-connector 9 represents the patient interface to the patient 7. A tracheal tube is arranged at the third end of the Y-connector 9, through which respiratory gas is inspired into and exhaled from the patient's lungs. In the embodiment of the ventilation system 1 shown here, the inspiratory tube 6 is interrupted by the connection of an optional humidification unit 11.The humidification unit 11 serves to warm and humidify the breathing gas in order to protect the airways and prevent secretion retention and airway irritation. Furthermore, a filter 10 is arranged near the ventilator 2 at the end of the expiratory tube 8.

[0057] In the embodiment shown here, the display unit 5 is integrated into the ventilator 2, as is the control unit 3. In other embodiments, it is possible-

[0058] 15012 P 4981 WOlieh that the display device 5 is part of another component of the ventilation system 1 or is designed as a separate element. Similarly, the control device 3 can also be designed as a separate element or be part of another component of the ventilation system 1.

[0059] The nebulizer 4 is located in the first section of the inspiratory tube 6, close to the ventilator 2 and, in the direction of the breathing gas, just before the humidifier 11. A mesh nebulizer or vibrating membrane nebulizer is preferably used as the nebulizer 4, which generates fine droplets of liquid, also called aerosols, from a liquid medication or drug substance. Ultrasonic or jet nebulizers can also be used. Since the nebulizer 4 is communicatively coupled to the ventilator 2, the parameters for configuring the nebulizer 4 can be entered directly on the ventilator 2. The nebulizer 4 is equipped with sensors of the type mentioned above (not shown), which provide data regarding the nebulization status, especially the medication level.Other possible sensors in the nebulization device 4 can be flow sensors, pressure sensors, temperature and humidity sensors, optical sensors, spectroscopy sensors and capnography sensors (CO2 sensors).

[0060] The ventilation system 1 is controlled via inputs and settings on the ventilator 2, in particular via the display unit 5, which is shown in Fig.

[0061] 2 will be explained in more detail. In principle, it is possible to distribute the display and control elements of the ventilator 2 and the other components of the ventilation system 1 across several devices. For reasons of practicality and time, it is preferable for medical personnel to control the entire ventilation system 1 from a single display and control unit, in this case integrated into the ventilator 2.

[0062] Fig. 2 shows an embodiment of a display device 5 as it may be configured in the ventilation system 1 according to the invention. The display device 5 comprises a display 12 on which at least one display element 13 and / or at least one control element 14 may be arranged. For example, the display 12 is a touch-sensitive display. Alternatively or additionally, the display device 5 may have other display or control elements such as buttons, sliders, rotary controls, LEDs, and the like.

[0063] 15012 P 4981 WO It is also possible that the display unit includes 5 interfaces or connections for connecting to other input or output devices.

[0064] The ventilation modes and other ventilation parameters can be set on the display unit 5. Stored ventilation and patient data can also be selected and adjusted via corresponding selection elements, allowing an operator to control and monitor the entire ventilation process via the display unit 5 and, if necessary, forward recorded data. The control unit 3 is designed so that the control of the ventilation process and the forwarding of ventilation data can be carried out essentially automatically.

[0065] The display unit 5 is specifically designed to simultaneously and in real time show the idle parameters of the nebulizer unit 4, in addition to the set data such as ventilation mode and other parameters. This allows the operating personnel to immediately draw conclusions about the idle time of the medication in the nebulizer unit 4 based on the displayed data and to act accordingly. For example, a traffic light-like display with the colors red, orange, and green can indicate the trend of an idle parameter. In conjunction with the ventilation mode display, medical personnel can deduce whether the selected ventilation strategy is still appropriate or needs to be changed or discontinued. The information displayed on the display unit 5 thus illustrates, for example, how nebulization affects the patient in combination with specific ventilation modes.Changes in idle parameters can also be visualized and compared, for example, with standard curves or historical data from the ventilation of other or the same patient.

[0066] The subject matter of the present invention is a ventilation system that enables the integration of nebulization parameters into the ventilation process, is simply structured and easy to assemble as an integrated system, and enables reliable and effective ventilation of a patient with optimized drug delivery through the nebulization device through a dynamic interaction of its components.

[0067] 15012 P 4981 WOList of reference marks:

[0068] 1 ventilation system

[0069] 2 ventilators

[0070] 3 Control unit

[0071] 4. Nebulizing device 5. Display device

[0072] 6 Inspiration hose

[0073] 7 patients

[0074] 8 Expiration tube 9 Y-piece

[0075] 10 filters

[0076] 11 Humidification unit 12 Display

[0077] 13 Display element

[0078] 14 Control element

[0079] 15. Ventilation circuit

[0080] 15012 P 4981 WO

Claims

Claims 1. Ventilation system (1) for ventilating a patient (7) with respiratory gas, comprising a ventilator (2), a nebulizer (4), a control unit (3) and a display unit (5), wherein the control unit (3) is communicatively connected to the ventilator (2), the nebulizer (4) and the display unit (5), wherein the display device (5) is configured to display data from the ventilator (2), the nebulizer (4) and / or the control device (3) and / or to process inputs from an operator, wherein the control unit (3) is configured to control the nebulization unit (4) for drug delivery on the basis of at least one ventilation parameter, and wherein the control device (3) is further configured to calculate an idle time point, which indicates the expected idle time of a drug container in the nebulization device (4), on the basis of at least one idle time parameter and to output it on the display device (5).

2. Ventilation system (1) according to claim 1, characterized in that the at least one ventilation parameter is selected from a group comprising: Ventilation mode, Ventilation rate, Ventilation pressure, Airflow, Tidal volume Respiratory rate Inspiration time (I), Expiry time (E), 15012 P 4981 WO ratio of inspiration time to expiration time (I: E), River shape.

3. Ventilation system (1) according to one of the preceding claims, characterized in that the at least one idle parameter is selected from a group comprising: Nebulizer type Nebulization rate, Size of the drug reservoir in the nebulizer (4), drug level in the nebulizer (4), Rate of change in drug fill level, Nebulization duration, Power consumption of the nebulizing device (4), Ventilation rate, Ventilation mode, Time for inspiration, Expiration time, and ratio of inspiration time to expiry time (l:E).

4. Ventilation system (1) according to claim 3, characterized in that the idle time point is calculated based on the drug level and / or the rate of change of the drug level during an inspiration time.

5. Ventilation system (1) according to claim 3, characterized in that the at least one idle parameter comprises actually measured and / or stored values.

6. Respiratory system (1) according to one of the preceding claims, characterized in that it has a humidification device (11) for humidifying the respiratory gas, which is communicatively connected to the control device (4).

7. Ventilation system (1) according to claim 6, characterized in that the control device (3) is configured to actually calculate the idle time point. 15012 P 4981 WOliehe and / or stored data taken into account that are assigned to the humidification device (11).

8. Ventilation system (1) according to one of the preceding claims, characterized in that the nebulization device (4) has at least one sensor selected from the group comprising a capacitive sensor, a resistance sensor, a weight sensor, an ultrasonic sensor or an optical sensor.

9. Ventilation system (1) according to one of the preceding claims, characterized in that the display device (5) has a display of at least one of the following display elements (13): Medication level in the nebulizer (4), Expired nebulization time, remaining nebulization time, Idle time point.

10. Ventilation system (1) according to one of the preceding claims, characterized in that the control device (3) and / or the display device (5) is configured to output an electrical, optical, acoustic or haptic alarm signal.

11. Ventilation system (1) according to one of the preceding claims, characterized in that the data of the ventilator (2) and the nebulization device (4) are displayed side by side on the display device (5).

12. Ventilation system according to one of the preceding claims, characterized in that the display device (5) comprises operating elements (14) which can be activated by an operator to actuate the nebulization device (4). 15012 P 4981 WO

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