A dissolving microneedle patch integrates an insoluble microfiber network in its substrate to create a drug reservoir for high-capacity delivery.
Integrating a planar glucose sensor into the infusion set reduces insertion sites and complexity while maintaining portable fluid delivery.
An ingestible pill uses a gas-generating patch that expands against the intestinal wall, ensuring consistent medication release through hollow needles.
Localized depressed surfaces prevent step formation during pattern transfer, improving microneedle array precision and productivity.
Heat-generating microneedles shorten lag time and increase release rates by accelerating dissolution, resolving interrupted delivery caused by short dwell times.
Segmentation and dynamic control principles stabilize bioavailability by enabling variable administration rates through a segmented microneedle array.
A touch-actuated micropump uses a phase-change fluid chamber to deflect a membrane and pump drug compounds through a needle into the vascular system.
A microneedle sheet uses water-soluble polysaccharide to provide bending resistance.
Flexible polymer cover secured by a gasketed cincture seals the handheld device interior.
Transcutaneous multimodal delivery device uses dissolvable microneedles to penetrate burn eschar and release therapeutic agents directly into the wound bed.
Vacuum adsorption stabilizes electroforms during resin injection, resolving fixation instability and deformation issues in mold manufacturing.
Recessed receiving sections in microneedle projections store freeze-dried drugs to increase capacity without reducing piercing strength.
A glucose sensor switches measurement potentials to adapt electron transfer pathways.
A tubular microneedle applicator uses a freely movable cap to release a piston against spring bias, enabling compact device construction.
A microneedle casting system uses a porous membrane to deliver liquid under vacuum pressure for precise mold replication.
An adhesive member with rigidity of 1.3 MPa•mm4 or more resists skin elasticity, preventing microneedle floating and ensuring stable drug delivery.
Optimizing the ratio of supporting surface area to projection length minimizes skin deformation while maintaining piercing reliability.