Muscular Disorder TRIZ Cases
- Stapled Cell-Penetrating Peptides for Oligonucleotide Delivery
Stapled cell-penetrating peptides conjugate to oligonucleotides via bi-functional linkers, reducing toxicity while maintaining cellular uptake.
- D-beta-hydroxybutyrate Ester for Muscle Preservation
D-beta-hydroxybutyrate ester reduces muscle glycogen loss and protein breakdown during intense exercise.
- Fibrosis Stabilization via Multi-Target Pathway Inhibition
Agents stabilize fibrosis by inhibiting matrix remodeling while promoting physiological wound healing.
- Anti-pro/latent-myostatin Antibodies for Muscle Atrophy
Antibodies bind pro/latent Myostatin to block activation, avoiding side effects from broader TGFβ pathway inhibition.