Steroids TRIZ Cases
- SAGE-718 Synthesis Route With Achiral Epimer Separation
An industrial SAGE-718 route replaces chiral CO2 chromatography with achiral epimer separation, cutting complexity and improving yield.
- Triterpenoid NR4A1 Modulators for Apoptosis in Proliferative Disease
Modulating NR4A1 with triterpenoid compounds induces apoptosis and expands treatment options for cancer and other proliferative diseases.
- Isolithocholic Acid Nasal Spray for Respiratory Cytokine Control
Direct nasal delivery of isolithocholic acid derivatives bypasses gut-lung dilution to suppress airway cytokines and neutrophil influx.
- Cholesterol Derivative Synthesis from Phytosterols with Easier Purification
Microbial phytosterol conversion improves cholesterol derivative yield and purity while avoiding animal extraction and difficult purification.