Preparation method of 6-isopropenyl-3-methyl-9-decenyl acetate and intermediates thereof
Through the nucleophilic substitution reaction of 2-methyl-2,6-heptanede compound and 3-methylpentyl nucleophilic reagent, combined with the deprotection and acetylation steps, 6-isopropenyl-3-methyl-9-decene acetate was successfully prepared, solving the problems of low safety and yield in the prior art, and achieving efficient industrial preparation.
Patent Information
- Application Number
- CN202110778909.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2021-01-28
- Filing Date
- 2021-07-09
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2041-07-09
AI Technical Summary
The prior art is difficult to efficiently and safely prepare sufficient amounts of 6-isopropenyl-3-methyl-9-decene acetate, and there are problems of using toxic, explosive reagents and low yields, making it difficult to use in industrial use.
The nucleophilic substitution reaction was carried out with 2-methyl-2,6-heptanede compound and 3-methylpentyl nucleophilic reagent to form a protected 6-isopropenyl-3-methyl-9-decene compound, and 6-isopropenyl-3-methyl-9-decene acetate was prepared by deprotection and acetylation steps, avoiding oxidation reactions and improving safety and yield.
It has achieved efficient and safe preparation of 6-isopropenyl-3-methyl-9-decene acetate, which is suitable for biological or agricultural activity testing and applications, and has solved the difficulties in industrial preparation.