An anti-contamination kit for detecting IgM antibodies and a sealing method thereof

By designing the lifting, pulling and clamping components of the anti-contamination test kit, the position of the test tube is stabilized, the contamination problem caused by test tube shaking is solved, and the safe storage and convenient operation of antibodies are achieved.

CN116812330BActive Publication Date: 2025-09-12ZHENJIANG JINTAI MEDICAL LAB CO LTD
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Patent Information

Application Number
CN202310885921.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-07-19
Publication Date
2025-09-12
Estimated Expiration
2043-07-19

AI Technical Summary

Technical Problem

When storing serum samples, the test tubes are easily shaken and broken, increasing the risk of IgM antibody contamination.

Method used

An anti-contamination test kit is designed, which includes a test kit body, a cover, a lifting component, a pulling component and a clamping component. Through the synergistic effect of these components, the position of the test tube is stabilized to avoid shaking and breakage.

Benefits of technology

It improves the stability of the test tube during storage, prevents antibody contamination, facilitates the removal and sealing of the test tube, and reduces the risk of breakage.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the technical field of antibody storage, and specifically to an anti-contamination test kit for detecting IgM antibodies and a sealing method thereof, comprising: a test kit body, on which a cover plate is rotatably mounted; a loading assembly, which comprises a No. 1 support plate and a No. 2 support plate; a lifting assembly, which can drive the No. 1 support plate and the No. 2 support plate to move toward the upper part of the test kit body when the cover plate is opened; a pulling assembly, which is arranged between the No. 1 support plate and the No. 2 support plate, and can move the No. 2 support plate toward the No. 1 support plate when the No. 1 support plate rises to a high point of its travel; a clamping assembly, which is arranged between the No. 1 support plate and the test kit body, and is connected to an arc-shaped rubber piece, and can drive the arc-shaped rubber piece to abut against a test tube inserted between the No. 1 support plate and the No. 2 support plate when the No. 1 support plate descends to a low point of its travel, so as to prevent the test tube from shaking in the test kit and breaking.
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Description

Technical Field

[0001] The present invention relates to the technical field of antibody storage, in particular to an anti-pollution kit for detecting IgM antibodies and a sealing method thereof. Background Art

[0002] IgM antibodies have powerful bactericidal, complement activation, immune regulation, and agglutination properties, and are also involved in the pathological processes of certain autoimmune diseases and hypersensitivity reactions. The most commonly used methods for measuring IgM antibody levels in serum are single-way immunodiffusion and immunoturbidimetry, but the latter has gradually replaced the former.

[0003] After obtaining the serum sample, the sample needs to be stored, and serum samples are generally obtained in large quantities. When storing, the serum sample needs to be placed in a test tube first, and the test tube is placed in a test kit for storage. In order to improve the stability of the test tube in the test kit, a test tube rack needs to be set in the test kit. In order to facilitate the insertion of the test tube, the placement hole on the test tube rack is generally larger than the diameter of the test tube. Although this facilitates the insertion of the test tube, it also causes the test tube to shake easily in the test tube rack, and there is a risk of the test tube breaking and causing IgM antibody contamination. Summary of the Invention

[0004] The object of the present invention is to provide an anti-contamination kit for detecting IgM antibodies and a sealing method thereof, so as to solve the problems raised in the above background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] An anti-contamination kit for detecting IgM antibodies, comprising:

[0007] a reagent kit body, on which a cover plate is rotatably mounted;

[0008] A loading assembly is disposed in the reagent kit body, and the loading assembly includes a first support plate and a second support plate;

[0009] a lifting assembly connected to the rotating shaft of the first support plate and the cover plate, wherein when the cover plate is opened, the lifting assembly can drive the first support plate and the second support plate to move toward the upper part of the reagent box body;

[0010] a pulling assembly, disposed between the first support plate and the second support plate, wherein the pulling assembly is capable of causing the second support plate to move toward the first support plate when the first support plate rises to a high point of travel;

[0011] The clamping assembly is arranged between the No. 1 support plate and the test kit body. The clamping assembly is connected to an arc-shaped rubber part, and the clamping assembly can drive the arc-shaped rubber part to abut the test tube inserted between the No. 1 support plate and the No. 2 support plate when the No. 1 support plate descends to the low point of the stroke.

[0012] As a further solution of the present invention: the first support plate is provided with a plurality of through holes, and the second support plate is provided with a plurality of supporting bases matching the through holes;

[0013] A plurality of No. 1 guide rods are diagonally arranged on the No. 2 support plate, and the engaging sliding portion arranged on the No. 1 support plate can slide on the No. 1 guide rod.

[0014] As a further embodiment of the present invention, the pulling assembly includes a deflection rod rotatably connected to the second support plate, a first pulley rotatably mounted on one end of the deflection rod away from the second support plate, and the first pulley is capable of rolling in a first horizontal groove formed on a side of the first support plate;

[0015] The pulling assembly further includes an abutment structure provided between the side wall of the reagent box body and the deflection rod.

[0016] As a further solution of the present invention: the abutment structure includes a second pulley rotatably mounted on the deflection rod and an inclined baffle arranged on the side wall of the reagent box body, and the second pulley can drive the deflection rod to rotate under the obstruction of the inclined baffle.

[0017] As a further embodiment of the present invention, the lifting assembly includes an incomplete gear coaxially fixedly connected to the rotating shaft of the cover plate, the incomplete gear is adapted to be rotatably mounted on the reagent box body, and the rotating shaft of the complete gear passes through the reagent box body and is connected to a bevel gear set disposed within the reagent box body;

[0018] The lifting assembly further includes a driven structure disposed between the first support plate and the reagent box body, and the driven structure is connected to the bevel gear set via a belt.

[0019] As a further solution of the present invention: the driven structure includes a turntable rotatably mounted in the reagent box body, and a third pulley is rotatably mounted at an eccentric position of the turntable;

[0020] The driven structure further comprises a connecting member fixedly connected to the first support plate, a lifting groove body is formed on the connecting member, and the third pulley can roll in the lifting groove body.

[0021] As a further solution of the present invention: the lifting trough body includes a No. 2 horizontal trough and a groove provided on the connecting member, and the groove is connected to one end of the No. 2 horizontal trough.

[0022] As a further embodiment of the present invention, the clamping assembly includes an abutment member slidably disposed on the first support plate, the abutment member being fixedly connected to the arc-shaped rubber member, and two protruding shafts being symmetrically disposed on both sides of the abutment member, the protruding shafts being adapted to guide plates disposed on the side walls of the reagent box body;

[0023] The guide plate includes an inclined plate and a vertical plate;

[0024] The clamping assembly further includes an elastic structure connecting the abutment member and the first support plate.

[0025] As a further solution of the present invention: the elastic structure includes a retardation groove provided on the side of the first support plate and a retardation block provided on the abutment member, and the retardation block is capable of sliding in the retardation groove;

[0026] A transverse shaft slidably connected to the hysteresis block is installed in the hysteresis groove. A cylindrical spring is sleeved on the transverse shaft. One end of the cylindrical spring is connected to the inner wall of the hysteresis groove, and the other end is connected to the hysteresis block.

[0027] A method for sealing IgM antibodies using the kit comprises the following steps:

[0028] Step 1: Open the cover, place the solution containing IgM antibody into the test tube, and seal the end of the test tube with a sterile rubber stopper;

[0029] Step 2: Place the blocked test tubes into the through holes one by one, and make the bottoms of the test tubes contact the supporting base;

[0030] Step 3: After the through-holes and the supporting base are filled with test tubes, close the cover;

[0031] Step 4: During the closing process of the cover, the cover drives the No. 1 support plate and the No. 2 support plate toward the interior of the reagent box body through the lifting assembly. At the same time, the No. 2 support plate moves away from the No. 1 support plate under the action of the pulling assembly, and the No. 1 support plate moves to a position close to the top of the test tube;

[0032] Step 5: Continue to close the cover until the No. 1 support plate and the No. 2 support plate descend to the end of their travel. The clamping assembly moves, driving the arc-shaped rubber part close to the top of the test tube and abutting against the top of the test tube until the cover is completely closed and the seal is completed.

[0033] Compared with the prior art, the present invention has the following beneficial effects:

[0034] The lifting assembly is provided to avoid interference between the test tube and the cover, and to make the No. 1 support plate, the No. 2 support plate and the cover more stable when the cover is fully opened, so that the position of the test tube is more stable when taking the test tube. On the other hand, when the cover is fully opened, the test tube will protrude from the reagent box body, making it easier for the tester to take it, and avoiding the test tube being completely placed inside the reagent box body, which makes it inconvenient for the tester to take it, resulting in unstable taking and then the test tube breaking.

[0035] By providing a pulling assembly, when the No. 1 support plate and the No. 2 support plate are in the reagent box body, the No. 1 support plate is at the upper end of the test tube, so that the two ends of the test tube are limited, making the test tube more stable. At the same time, when the No. 1 support plate and the No. 2 support plate move upward, the test tube will move toward the No. 1 support plate under the drive of the No. 2 support plate, so that the No. 1 support plate is in the middle position of the test tube, so that when the tester takes the test tube, there is a larger position for taking it, and it is avoided that the test tube is not easy to take or even broken due to the test tube being too small. The convenience of taking is further improved and the antibody contamination due to the broken test tube is avoided.

[0036] By setting up the clamping assembly, when the No. 1 support plate and the No. 2 support plate move to the end of the stroke, the abutment piece can drive the arc-shaped rubber piece to abut against the test tube, thereby improving the strength of the fixation inside the test tube, and avoiding the test tube from shaking due to unstable clamping when the test tube is stored in the reagent box body, and eventually leading to breakage and antibody contamination. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 A schematic structural diagram of an embodiment of an anti-contamination kit for detecting IgM antibodies;

[0038] Figure 2 A schematic diagram of the structure of a clamping component and a pulling component in one embodiment of an anti-contamination kit for detecting IgM antibodies;

[0039] Figure 3 An exploded view of a clamping assembly in one embodiment of an anti-contamination kit for detecting IgM antibodies;

[0040] Figure 4 for Figure 3 A magnified view of the structure at point A;

[0041] Figure 5 An exploded view of a pulling component in one embodiment of an anti-contamination kit for detecting IgM antibodies;

[0042] Figure 6 A schematic structural diagram of a lifting assembly in one embodiment of an anti-contamination kit for detecting IgM antibodies;

[0043] Figure 7 A schematic structural diagram of a connector and a lifting tank in one embodiment of an anti-contamination kit for detecting IgM antibodies;

[0044] In the figure: 1. Test kit body; 2. Cover plate; 3. Support plate No. 1; 4. Support plate No. 2; 5. Through hole; 6. Support base; 7. Guide rod No. 1; 8. Engaging sliding part; 9. Horizontal groove No. 1; 10. Pulley No. 1; 11. Deflection rod; 12. Pulley No. 2; 13. Oblique baffle; 14. Delay groove; 15. Horizontal axis; 16. Column spring; 17. Abutment; 1701. Delay Block; 18. Protruding shaft; 1901. Inclined plate; 1902. Vertical plate; 19. Guide plate; 20. Arc-shaped rubber piece; 21. Incomplete gear; 22. Complete gear; 23. Bevel gear set; 24. Belt; 25. Turntable; 26. Pulley No. 3; 27. Vertical plate; 28. Guide rod No. 2; 29. ​​Connector; 30. Lifting trough; 3001. Horizontal trough No. 2; 3002. Groove. DETAILED DESCRIPTION

[0045] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0046] In addition, when an element in the present invention is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. When an element is referred to as being "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only implementation method.

[0047] See also Figures 1 to 7 In an embodiment of the present invention, an anti-contamination kit for detecting IgM antibodies includes: a kit body 1, a loading component, a lifting component, a pulling component and a clamping component.

[0048] A cover plate 2 is rotatably mounted on the reagent kit body 1;

[0049] The loading assembly is arranged in the reagent box body 1, and the loading assembly includes a No. 1 support plate 3 and a No. 2 support plate 4. The No. 1 support plate 3 is provided with a plurality of through holes 5, and the No. 2 support plate 4 is provided with a plurality of supporting bases 6 matching the through holes 5. The No. 2 support plate 4 is provided with a plurality of No. 1 guide rods 7 diagonally, and the interlocking sliding portion 8 provided on the No. 1 support plate 3 can slide on the No. 1 guide rod 7;

[0050] The lifting assembly is connected to the rotating shaft of the first support plate 3 and the cover plate 2. When the cover plate 2 is opened, the lifting assembly can drive the first support plate 3 and the second support plate 4 to move toward the upper part of the reagent box body 1;

[0051] The lifting assembly includes an incomplete gear 21 coaxially fixedly connected to the rotating shaft of the cover plate 2, and the incomplete gear 21 is adapted to a complete gear 22 rotatably mounted on the reagent box body 1. The rotating shaft of the complete gear 22 passes through the reagent box body 1 and is connected to a bevel gear set 23 provided in the reagent box body 1;

[0052] The lifting assembly also includes a driven structure provided between the No. 1 support plate 3 and the reagent box body 1, the driven structure is connected to the bevel gear set 23 via a belt 24, the bevel gear set 23 includes a No. 1 bevel gear and a No. 2 bevel gear rotatably mounted on the reagent box body 1 and meshing with each other, the No. 1 bevel gear is coaxially fixedly connected to the full gear 22, the No. 2 bevel gear is connected to the driven structure via a belt 24, the driven structure includes a turntable 25 rotatably mounted in the reagent box body 1, and a No. 3 pulley 26 is rotatably mounted at an eccentric position of the turntable 25;

[0053] The driven structure further includes a connecting member 29 fixedly connected to the first support plate 3, and a lifting trough 30 is formed on the connecting member 29. The third pulley 26 can roll in the lifting trough 30, wherein the lifting trough 30 includes a second horizontal groove 3001 and a groove 3002 provided on the connecting member 29, and the groove 3002 is connected to one end of the second horizontal groove 3001;

[0054] Furthermore, a vertical plate 27 is fixed to one side of the No. 1 support plate 3 , and the vertical plate 27 is slidably connected to a No. 2 guide rod 28 provided on the reagent box body 1 .

[0055] When in use, the cover 2 is opened to make its rotating shaft drive the incomplete gear 21 to rotate, wherein the upper part of the incomplete gear 21 has teeth and the lower part has no teeth. During the first 90° process of opening the cover 2, the toothed part of the incomplete gear 21 is separated from the complete gear 22, and the complete gear 22 rotates. At this time, the No. 1 support plate 3 and the No. 2 support plate 4 are inside the reagent box body 1 to avoid interference between the test tube and the cover 2. When the cover 2 is opened from 90° to 180°, the toothed part of the incomplete gear 21 will mesh with the complete gear 22 and drive the complete gear 22 to rotate. At this time, the complete gear 22 will drive the turntable 25 to rotate through the bevel gear set 23 and the belt 24. In the initial state, the axis connecting the No. 3 pulley 26 and the turntable 25 is horizontal. When the turntable 25 rotates, the No. 3 pulley 26 will make a circular motion and move along the No. 2 pulley. The horizontal slot 3001 moves in the length direction until the turntable 25 follows the full gear 22 to rotate 90 degrees, so that the axis line connecting the No. 3 pulley 26 and the turntable 25 is in a vertical state. At this time, the No. 3 pulley 26 moves to the end of the No. 2 horizontal slot 3001. Under the stopper at the end of the No. 2 horizontal slot 3001, the turntable 25 stops rotating, thereby fixing the position of the cover plate 2, improving the position stability of the cover plate 2, and when the No. 3 pulley 26 moves to the end of the No. 2 horizontal slot 3001, the No. 3 pulley 26 will enter the groove 3002, and the center line connecting the No. 3 pulley 26 and the turntable 25 remains in a vertical state, avoiding the turntable 25 from rotating in the opposite direction due to the total weight of the No. 1 support plate 3, the No. 2 support plate 4 and the test tube inserted therebetween, thereby further improving the stability of the No. 1 support plate 3, the No. 2 support plate 4 and the cover plate 2 when the cover plate 2 is fully opened;

[0056] Secondly, when the turntable 25 rotates 90°, the connecting piece 29 will move upward, driving the No. 1 support plate 3 to move upward, so that the test tubes on the No. 1 support plate 3 and the No. 2 support plate 4 protrude from the reagent kit body 1, thereby making it convenient for the test personnel to take them, and avoiding the test tubes being completely placed inside the reagent kit body 1, making it inconvenient for the test personnel to take them, resulting in unstable taking and then the test tubes being broken.

[0057] Through the above arrangement, on the one hand, interference between the test tube and the cover 2 is avoided, and when the cover 2 is fully opened, the No. 1 support plate 3, the No. 2 support plate 4 and the cover 2 are more stable, so that the position of the test tube is more stable during the process of taking the test tube. On the other hand, when the cover 2 is fully opened, the test tube will protrude from the reagent box body 1, so that it is convenient for the tester to take it, and avoid the test tube being completely placed inside the reagent box body 1, which makes it inconvenient for the tester to take it, resulting in unstable taking and then the test tube breaking.

[0058] See also Figure 1 、 Figure 2 、 Figure 3 、 Figure 5、 Figure 6 The pulling assembly is arranged between the first support plate 3 and the second support plate 4, and the pulling assembly can move the second support plate 4 toward the first support plate 3 when the first support plate 3 rises to the highest point of the stroke;

[0059] The pulling assembly includes a deflection rod 11 rotatably connected to the second support plate 4, and a first pulley 10 is rotatably mounted on one end of the deflection rod 11 away from the second support plate 4. The first pulley 10 can roll in a first horizontal groove 9 formed on the side of the first support plate 3;

[0060] The pulling assembly also includes an abutment structure arranged between the side wall of the reagent box body 1 and the deflection rod 11, and the abutment structure includes a second pulley 12 rotatably mounted on the deflection rod 11 and an inclined baffle 13 arranged on the side wall of the reagent box body 1. The second pulley 12 can drive the deflection rod 11 to rotate under the obstruction of the inclined baffle 13.

[0061] When the No. 1 support plate 3 rises, it will drive the No. 2 support plate 4 connected thereto to move upward. At this time, under the action of the gravity of the No. 2 support plate 4, the deflection rod 11 is in a vertical state, and the No. 1 pulley 10 on the deflection rod 11 is at the end of the No. 1 horizontal groove 9. When the No. 1 support plate 3 and the No. 2 support plate 4 move to the end of the stroke, the No. 2 pulley 12 on the deflection rod 11 will abut against the inclined baffle 13. At this time, under the guidance of the inclined baffle 13, the deflection rod 11 will rotate, causing the No. 1 pulley 10 to do a circular motion. When the No. 1 pulley 10 does a circular motion, the No. 1 pulley 10 will move along the length direction of the No. 1 horizontal groove 9, and the No. 2 support plate 4 will move toward the No. 1 support plate 3, so as to move the test tube whose bottom is in contact with the No. 2 support plate 4 toward the upper part of the No. 1 support plate 3, and after the No. 1 support plate 3 and the No. 2 support plate 4 rise to the highest point of the stroke, the No. 1 support plate 3 is in the middle position of the test tube, and the length of the test tube protruding from the No. 1 support plate 3 is longer, so that when the tester takes the test tube, the position for taking is larger, and it is avoided that the test tube is inconvenient to take due to the too small taking part of the test tube or even the test tube is broken due to unstable taking.

[0062] Through the above arrangement, when the No. 1 support plate 3 and the No. 2 support plate 4 are in the reagent box body 1, the No. 1 support plate 3 is at the upper end of the test tube, so that the two ends of the test tube are limited, making the test tube more stable. At the same time, when the No. 1 support plate 3 and the No. 2 support plate 4 move upward, the test tube will move toward the No. 1 support plate 3 under the drive of the No. 2 support plate 4, so that the No. 1 support plate 3 is in the middle position of the test tube, so that when the tester takes the test tube, the position for taking is larger, and it is avoided that the test tube is too small to take the test tube, which causes inconvenience in taking or even the test tube is broken due to unstable taking, further improving the convenience of taking, and avoiding the contamination of antibodies due to the breakage of the test tube.

[0063] See also Figures 2 to 4 The clamping assembly is arranged between the first support plate 3 and the reagent box body 1, and the clamping assembly is connected to an arc-shaped rubber member 20. When the first support plate 3 is lowered to the lowest point of the stroke, the clamping assembly can drive the arc-shaped rubber member 20 to abut against the test tube inserted between the first support plate 3 and the second support plate 4;

[0064] The clamping assembly includes an abutment member 17 slidably disposed on the first support plate 3, the abutment member 17 is fixedly connected to the arc-shaped rubber member 20, and two protruding shafts 18 are symmetrically disposed on both sides of the abutment member 17, and the protruding shafts 18 are adapted to the guide plates 19 disposed on the side walls of the reagent box body 1;

[0065] The guide plate 19 includes an inclined plate 1901 and a vertical plate 1902;

[0066] The clamping assembly further includes an elastic structure connecting the abutment member 17 and the first support plate 3. The elastic structure includes a retardation groove 14 provided on the side of the first support plate 3 and a retardation block 1701 provided on the abutment member 17. The retardation block 1701 is capable of sliding in the retardation groove 14.

[0067] A transverse shaft 15 slidably connected to the hysteresis block 1701 is also installed in the hysteresis groove 14. A cylindrical spring 16 is sleeved on the transverse shaft 15. One end of the cylindrical spring 16 is connected to the inner wall of the hysteresis groove 14, and the other end is connected to the hysteresis block 1701.

[0068] When the test tubes are filled with the through holes 5 and the supporting base 6, the cover plate 2 is closed. At this time, the No. 1 support plate 3 and the No. 2 support plate 4 will move downward. During this process, the distance between the No. 1 support plate 3 and the No. 2 support plate 4 will decrease. At the same time, the test tube will move downward relative to the No. 1 support plate 3 until the No. 1 support plate 3 is at the same height as the upper end of the test tube. Then, as the No. 1 support plate 3 and the No. 2 support plate 4 continue to descend, the convex shaft 18 will abut against the inclined plate 1901, and under the drive of the inclined plate 1901, the abutment 17 moves toward the test tube, compressing the cylindrical spring 16 while making the arc-shaped rubber part 20 abut against the test tube to increase the strength of the test tube being fixed. At the same time, as the No. 1 support plate 3 and the No. 2 support plate 4 continue to move, the convex shaft 18 will slide on the vertical plate 1902 to prevent the abutment 17 from moving excessively and crushing the test tube.

[0069] Through the above arrangement, when the No. 1 support plate 3 and the No. 2 support plate 4 move to the end of the stroke, the abutment member 17 can drive the arc-shaped rubber member 20 to abut against the test tube, thereby improving the strength of the fixation inside the test tube, and avoiding the test tube from shaking due to unstable clamping when the test tube is stored in the reagent kit body 1, and eventually causing breakage and antibody contamination.

[0070] As an embodiment of the present invention, a method for sealing IgM antibodies using the kit is also proposed, comprising the following steps:

[0071] Step 1: Open the cover plate 2, place the solution containing IgM antibodies in the test tube, and seal the end of the test tube with a sterile rubber stopper;

[0072] Step 2: Place the blocked test tubes into the through holes 5 one by one, and make the bottoms of the test tubes contact the supporting base 6;

[0073] Step 3: After the through-holes 5 and the supporting base 6 are filled with test tubes, the cover 2 is closed;

[0074] Step 4: During the closing process of the cover 2, the cover 2 drives the first support plate 3 and the second support plate 4 toward the interior of the reagent box body 1 through the lifting assembly. At the same time, the pulling assembly causes the second support plate 4 to move away from the first support plate 3, and the first support plate 3 to move to a position close to the top of the test tube.

[0075] Step 5: Continue to close the cover 2. When the No. 1 support plate 3 and the No. 2 support plate 4 drop to the end of their travel, the clamping assembly moves, driving the arc-shaped rubber member 20 close to the top of the test tube and abutting against the top of the test tube until the cover 2 is completely closed and the seal is completed.

[0076] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be included therein. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0077] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A contamination-proof kit for detecting IgM antibodies, characterized in that: include: A reagent box body (1), wherein a cover plate (2) is rotatably mounted on the reagent box body (1); A loading assembly is arranged in the reagent box body (1), and the loading assembly includes a first support plate (3) and a second support plate (4); A lifting assembly connected to the rotating shaft of the first support plate (3) and the cover plate (2), wherein when the cover plate (2) is opened, the lifting assembly can drive the first support plate (3) and the second support plate (4) to move toward the upper part of the reagent box body (1); a pulling assembly, arranged between the first support plate (3) and the second support plate (4), wherein the pulling assembly is capable of causing the second support plate (4) to move toward the first support plate (3) when the first support plate (3) rises to a stroke high point; A clamping assembly is provided between the first support plate (3) and the reagent box body (1), the clamping assembly is connected to an arc-shaped rubber member (20), and the clamping assembly is capable of driving the arc-shaped rubber member (20) to abut against the test tube inserted between the first support plate (3) and the second support plate (4) when the first support plate (3) descends to the lowest point of the stroke; The first support plate (3) is provided with a plurality of through holes (5), and the second support plate (4) is provided with a plurality of supporting bases (6) matching the through holes (5); A plurality of No. 1 guide rods (7) are diagonally arranged on the No. 2 support plate (4), and the engaging sliding portion (8) arranged on the No. 1 support plate (3) is capable of sliding on the No. 1 guide rods (7); The pulling assembly comprises a deflection rod (11) rotatably connected to the second support plate (4); a first pulley (10) is rotatably mounted on one end of the deflection rod (11) away from the second support plate (4); the first pulley (10) is capable of rolling in a first horizontal groove (9) formed on the side of the first support plate (3); The pulling assembly further comprises an abutment structure provided between the side wall of the reagent box body (1) and the deflection rod (11); The abutment structure comprises a second pulley (12) rotatably mounted on the deflection rod (11) and an inclined baffle (13) provided on the side wall of the reagent box body (1); the second pulley (12) can drive the deflection rod (11) to rotate under the obstruction of the inclined baffle (13).

2. The anti-pollution kit for detecting IgM antibodies according to claim 1, wherein The lifting assembly comprises an incomplete gear (21) coaxially fixedly connected to the rotating shaft of the cover plate (2), the incomplete gear (21) being adapted to a complete gear (22) rotatably mounted on the reagent box body (1), the rotating shaft of the complete gear (22) passing through the reagent box body (1) and being connected to a bevel gear set (23) provided in the reagent box body (1); The lifting assembly further comprises a driven structure arranged between the first support plate (3) and the reagent box body (1), wherein the driven structure is connected to the bevel gear set (23) via a belt (24).

3. The anti-pollution kit for detecting IgM antibodies according to claim 2, wherein: The driven structure comprises a turntable (25) rotatably mounted in the reagent box body (1), and a third pulley (26) is rotatably mounted at an eccentric position of the turntable (25); The driven structure further comprises a connecting member (29) fixedly connected to the first support plate (3), a lifting trough (30) being formed on the connecting member (29), and the third pulley (26) is capable of rolling in the lifting trough (30).

4. The anti-pollution kit for detecting IgM antibodies according to claim 3, characterized in that: The lifting tank body (30) comprises a second horizontal groove (3001) and a groove (3002) provided on the connecting member (29), wherein the groove (3002) is connected to one end of the second horizontal groove (3001).

5. The anti-pollution kit for detecting IgM antibodies according to claim 1, characterized in that: The clamping assembly includes an abutment member (17) slidably arranged on the first support plate (3), the abutment member (17) is fixedly connected to the arc-shaped rubber member (20), and two convex shafts (18) are symmetrically arranged on both sides of the abutment member (17), and the convex shafts (18) are adapted to the guide plate (19) arranged on the side wall of the reagent box body (1); The guide plate (19) includes an inclined plate (1901) and a vertical plate (1902); The clamping assembly further comprises an elastic structure connecting the abutment member (17) and the first support plate (3).

6. The anti-pollution kit for detecting IgM antibodies according to claim 5, characterized in that: The elastic structure comprises a retardation groove (14) provided on the side of the first support plate (3) and a retardation block (1701) provided on the abutment member (17), wherein the retardation block (1701) is capable of sliding in the retardation groove (14); A transverse shaft (15) slidably connected to the hysteresis block (1701) is also installed in the hysteresis groove (14), and a cylindrical spring (16) is sleeved on the transverse shaft (15). One end of the cylindrical spring (16) is connected to the inner wall of the hysteresis groove (14), and the other end is connected to the hysteresis block (1701).

7. A method for sealing IgM antibodies using the kit according to claim 1, characterized in that: The following steps are involved: Step 1: Open the cover (2), place the solution containing IgM antibodies in the test tube, and seal the end of the test tube with a sterile rubber stopper; Step 2: Place the blocked test tubes in the through holes (5) in sequence, and make the bottoms of the test tubes contact the supporting base (6); Step 3: After the through-holes (5) and the supporting base (6) are filled with test tubes, the cover (2) is closed; Step 4: During the process of closing the cover (2), the cover (2) drives the No. 1 support plate (3) and the No. 2 support plate (4) to move toward the interior of the reagent box body (1) through the lifting assembly, and at the same time, under the action of the pulling assembly, the No. 2 support plate (4) moves away from the No. 1 support plate (3), and the No. 1 support plate (3) moves to a position close to the top of the test tube; Step 5: Continue closing the cover (2) until the No. 1 support plate (3) and the No. 2 support plate (4) descend to the end of their travel, and the clamping assembly actuates to drive the arc-shaped rubber member (20) close to the top of the test tube and abut against the top of the test tube until the cover (2) is completely closed and the seal is completed.

Citation Information

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